• Title/Summary/Keyword: GOT

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Studies on the serochemical status in dairy Holstein cows of reproductive disorder (불임유우의 혈청화학치에 관한 연구)

  • 이관복;신창호;김선희;임종목;최원식;박현기
    • Korean Journal of Veterinary Service
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    • v.20 no.2
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    • pp.177-182
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    • 1997
  • To make index on therapy or releasing from dairy holstein cows of reproductive disorder, the levels of serological sex hormones and total ALP, GOT, GPT, and serum protein were measured. The results obtained through the experiments are summarized as follows ; 1. The levels of FSH and estradiol in reproductive disorder group were significantly higher and lower than those in pregnant group and control group, respectively. (p<0.05) 2. The level of prolactin was showed mild difference in three groups and that of progesterone was reasonably higher in pregnant group with significance (p<0.05). 3. The activity of GPT was significantly higher and that of GOT was showed higher In reproductive disorder group, respectively ( p<0.05) 4. The level of total ALP was higher in reproductive disorder group, however no difference was showed between pregnant and control group. 5. The level of serum protein was followed as control, pregnant, and reproductive disorder with insignificance.

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Studies on the amino acid metabolism of young rice root (Part 3) - Effects of nitrogen, phosphorus, potassium and respiratory inhibitor on the enzyme activities of rice root - (수도근(水稻根)의 Amino산(酸) 대사(代謝)에 관한 연구 -제(第) 3 보(報) 수도근(水稻根)의 몇가지 효소(酵素)의 활성(活性)에 미치는 삼요소(三要素)및 호흡저해제(呼吸沮害劑)의 영향(影響))

  • Kim, Young Ung
    • Korean Journal of Soil Science and Fertilizer
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    • v.7 no.4
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    • pp.201-207
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    • 1974
  • Some effects of nitrogen, phosphorus, potassium and respiratory inhibitor on growth of rice plant and activity of GOT, GPT and peroxidase for the rice root were investigated. Obtained results were summarized as follows: 1. Growth of rice root and plant applied with $NO_3$-N in culture solution was generally increased in the length and weight compared with that of $NH_4$-N plot. On the other hand, the GOT, GPT and peroxidase activity was more increased in the $NH_4$-N plot than in the $NO_3$-N plot. 2. Oxidative power of ${\alpha}$-naphthylamine in rice root was stronger in the $NO_3$-N plot than in the $NH_4$-N plot. 3. When rice plant was cultured in the medium which did not supplied nitrogen, phosphorus or potassium, respectively, GOT activity was more decreased than GPT activity, while peroxidase activity was increased mostly in the potassium-free plot. 4. When rice plant was cultivated in the culture solution added respiratory inhibitor, NaF, plant height was shortened in the order of nitrogen-free > $NH_4$-H > urea-N > $NO_3$-N plot, and GOT and GPT activity was also decreased in the order of nitrogen-free > $NH_4$-N > urea-N > $NO_3$-N plot.

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Hepatotoxicity Reducing Effect of Ethanol Extracts from Fermented Youngia denticulata Houtt Kitamura in Ethanol-treated Rats (발효 이고들빼기(Youngia denticulata Houtt Kitamura) 에탄올 추출물이 알코올 투여로 손상시킨 흰쥐의 간독성 해소 효과)

  • Kim, Mee-Jung;Lee, Hyun-Koo
    • Journal of the East Asian Society of Dietary Life
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    • v.26 no.5
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    • pp.389-399
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    • 2016
  • This study was performed to investigate the hepatotoxicity reducing effect of ethanol extracts from Youngia denticulata Houtt Kitamura (YD) fermented by Aspergillus oryzae, which is well known as a Korean traditional meju microbe. Experimental rats were divided into 4 diets groups (six rats/group) (NC: normal control group, EC: ethanol supplemented control group, ENY: ethanol extracts 0.5% supplemented diets of the non-fermented YD group, EFY: ethanol extracts 0.5% supplemented diets of the fermented YD group). After feeding them for four weeks, the activities GOT and GPT in serum, contents of neutral lipid, total cholesterol, LPO and GSH, and activities of XO (O type) enzyme, SOD and GST in liver tissue were observed. Compared to the NC group, the GOT and GPT activities in the EC group were markedly increased by 87.91% and 57.02%, and the contents of neutral lipid, total cholesterol and LPO were increased by 77.51%, 18.56% and 193.86%, respectively. On the other hand, the GSH content was decreased by 29.52%. The activities of SOD and GST which are anti-oxidation-related enzymes, were decreased by 42.78% and 0.94%, respectively, compared to the NC group, but the XO (O type) enzyme activity was significantly increased by 70.83%. These results confirmed that the liver tissue and anti-oxidation system of the EC group had been damaged. Compared to the EC group, the GOT and GPT activities of the ENY and EFY groups were significantly decreased by 24.73~41.99% and 22.91~30.11%, respectively. The contents of neutral lipid, total cholesterol and LPO were decreased by 16.65~33.33%, 22.44~23.11% and 63.34~66.13%, respectively, but the GSH content was significantly increased by 24.61~35.60%. The GST activity was not significantly affected, but the SOD activity was significantly increased by 214.94~261.19%. The XO (O type) enzyme activity was significantly decreased by 40.34~51.20%. Compared to the ENY group, the GOT and GPT activities of the EFY group were significantly decreased by 22.93% and 9.34%, respectively. The plasma contents of neutral lipid, total cholesterol and LPO were decreased by 20.01%, 0.86% and 7.59%, respectively. The SOD activity was significantly increased by 21.52%, and the XO (O type) enzyme activity was decreased by 18.19%. Given decreasde TG, total cholesterol, LPO contents of liver tissue, GOT, GPT and XO activity, and increased SOD activity, these study results that ethanol extracts from fermented Youngia denticulata Houtt Kitamura may be effective in reducing hepatotoxicity.

Analysis of the Oral Health Knowledge and Practice of Teachers in Some Early Childhood Education Institutions (일부 유아교육기관 교사의 구강보건지식 및 실천정도 분석)

  • Kim, Soo-Hwa;Lim, Mi-Hee;Jung, Jae-Yeon;Hwang, Yoon-Sook;Lee, Sun-Mi
    • Journal of dental hygiene science
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    • v.10 no.5
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    • pp.379-385
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    • 2010
  • The purpose of this study was to examine the oral health knowledge and oral health practice of teachers in early childhood education institutions. The subjects in this study were 169 teachers who worked in early childhood education institutions. After a survey was conducted, the collected data were analyzed with a SPSSWIN 14.0 program. The findings of the study were as follows: 1. Concerning oral health knowledge, they got a mean of 7.97(9), 2.66(3), 2.86(5), 2.42(5) and 1.04(2) respectively in knowledge on dental caries, toothbrushing, periodontitis, fluoride and diet. Overall, they got a mean of 16.98 in 24 items, and the score corresponded to approximately 70 out of 100 points. 2. As for oral health practice, tongue cleaning(4.22) was what they did the most to take care of their oral health, and they just got 2.60 in regular dental checkup. Overall, they got about 3.11 in oral health practice. 3. Regarding relationship between general characteristics and oral health knowledge, the teachers who were in their 30s got 17.47 in overall oral health knowledge, and those with a career of five to less than 10 years got 17.50. The teachers who received college or higher education got 17.27, and the principals got 18.26. Those who had ever received education on oral health got 17.01. But the gaps between them and the others were not statistically significant. 4. As to connections between general characteristics including age and oral health practice, restricted sugar intake, regular dental checkup, the use of oral hygiene supplies, tongue cleaning and overall oral health practice were more prevailing among the older teachers, and the gaps between them and the younger teachers were statistically significant. 5. In terms of relationship between oral health knowledge and oral health practice, there was no statistically significant relationship between the two on the whole, but better oral health knowledge led to better oral health practice in each part. This study shows that various oral health education programs for the kindergarten teachers should be developed and continuous education through the programs is important to improve the knowledge of oral health and to change oral health behavior.

A STUDY ON MENTAL HEALTH STATE OF HIGH SCHOOL STUDENTS (고등학생의 정신건강 상태에 관한 연구 -SCL-90을 이용, 서울시 인문계 1 . 3학년을 중심으로-)

  • 김은주
    • Korean Journal of Health Education and Promotion
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    • v.5 no.2
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    • pp.110-141
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    • 1988
  • This study was conducted to find out the mental health state of high school students. First-year students and third-year students af liberal high schools is Seoul were subject to this study. Questionnaire of Symptom Checklist-90 and various factors was adopted for the survey. A total of 916 questionnaires was sellected for the analysis, and the results are obtained as follows; 1) The characteristics in responses to mental health scale showed that obsessive-compulsive scale score was the highest, followed by interpersonal-sensitivity, depression, hostility, and anxiety. The subject group of the students showed higher scores in nine symptom dimensions except somatization than other normal group. 2) Girl-students showed higher scores than boy-students in somatization, depression, and anxiety, whereas the opposite was true in hostility. 3) Third-year students got high scores, in somatization, anxiety and Depression. 4) Parental marriage state of the repondents showed significant differences in nine symptom dimensions of mental health. Scores of the students with parents was the lowest, followed by those of students with only mother, only father and the rest(no parents, divorced, sepaerated, step-parent) in increasing order. 5) Smoking students showed high score in obsessive-compulsive, depression, hostility, paranoid ideation, and psychoticism. Especially in hostility, they got much higher score. 6) Students with poor record at school got higher scores in every symptom dimension than those with good record at school, especially in obsessive-compulsive and depression scale. 7) Parents' attitude toward student showed significant effect on every scale. Students under over-expectation or indifference from parents were in bad mental health state. 8) Students who have advisor proved to be in better mental health state than those who never consult their personal problems with others. 9) He who has family history got higher scores in some scales. 10) Respondents who looked upon what they have learned in high school as being rather an obstacle to sound social life got high scores in all the symptom dimensions and next came those of the students who answered that there were a lot of unnecessary things in their learning. 11) Those for whom it would not quite necessary to enter college if there were little formal schooling discrimination in society got high scores in obsessive-compulsive, interpersonal sensitivity, depression, hostility, and in psychoticism, especially higher in obsessive-compulsive scale. 12) Mental health state of the students who are influenced by the social surroundings, mass media, and the home environments showed high score in 8 symptom dimensions. 13) Abnormal response frequency of this sample is as follows; 24.0% of boys, 23.8% of girls, 22.5% of the first-year students, and 26.9% of the third-year students. There were significant difference among the grades. 14) The factors of distinctive correlation between the dimensions of SCL-90 and 16 factors were the father's negative attitude and depression, negative responses on teaching contents and anxiety, and smoking and hostility. In conclusion, mental health state of liberal highschool students on the whole showed worse than other normal groups. It had close terms with relation with their parents, schoolwork, smoking, teaching contents, the social surrounding, mass media, and the home environments. Thus I believe there need not only mental health education of students, training of teachers, counceling of parents, but also changes in teaching contents, and the improvement of educational system and the social surroundings under the national support.

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A Clinical study on Pediatric Bronchial Asthma (소아천식에 대한 임상적 고찰)

  • Kim, Yun-Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.16 no.1
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    • pp.133-148
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    • 2002
  • Objective : This study was to investigate more effective oriental medical treatment for Pediatric Bronchial Asthma Method : Aroma therapy and Herbal medicine was given to 28 pediatric bronchial asthma patients(19 males and 9 females) for about 5months from the First, August 1999 The Fifth, January 2002. Results: 1. Demographic factor : The sample consisted of 28 persons among whom 19 were male, 9 were female. The age ranges from 1 year old to 6 year old. Less than 2 year old were 4 and 2-6 year old were 20. 2.Residence : Apartment and villar dwellers were 19(67.9%), Residential street divellers were 9(32.1%). 3.Age distribution at on set : 6(21.4%) fell ill befor 1 year old and 22(78.6%) fell ill after 1 year old 4. The period of illness : 9(32.2%) suffered during 1-3 year and 6(21.4%) suffered during 6 mouth-1year and 6(21.4%) suffered during more than 3 year. 5. Frequency of the symptoms : The symptoms appeared 2-3 times a year in the case of 16(57.2%), one time a year in the case of 1, 4 times a year in the case of 6(21.4%). 6. Concomitance symptoms : All experienced coughing sign, wheezing, 23(82.1%) experienced epistaxis, nose dripping, 13(46.4%) got fever, anorexia. 7. Past history of illness : 16(57.1%) got brochiolitis, brochitis, 12(42.9%) suffered pneumonia, 9(32.1%) had allergic rhinitis. 2 had allergic rhinitis, sinusitis, atopic dermatitis, bronchial asthma, 3 got atopic dermatitis, bronchial asthma and 7 had allergic rhinitis, sinusitis, bronchial asthma, 8. Family disease : In the case of family disease, 21(75%) had allergic dermatitis, 9(42.9%) had bronchial asthma, 8(38.1%) had allergic dermatitis. 9. The symptoms became very severe in the change of season in the case of 13(46.4%) and in the case of 11(39.3%), the change of season made no difference 10. Associated caused of induction symtoms : 28(100%) got sick by common cold, infectional disease, 8(28.6%) got sick by cold food, cold air 11.The kind of therapy : 15(53.6%) got oriental therapy after occidental therapy, 11(39.3%) took only oriental therapy. 12. Improvement degree of each symptoms : In the case of cough and wheeze that are the main symptoms of bronchial asthma, 78.6% and 64.3% of the patients replied < improvement > and in the case of dyspnea, tachypnea 41.7% of the patients replied . In other symptoms, all replied 13. Degree of satisfaction : 19(67.9%) replied , 2(7.1%) replied . Conclusion : Herbal medicine and aroma therapy proved to be a very effective oriental medical treatment for pediatric bronchial asthma.

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Factors Affecting the Postoperative Outcome in Adult Cardiac Surgery with Cardiopulmonary Bypass (심폐바이패스를 이용한 성인 심장수술 시 환자회복에 영향을 미치는 인자)

  • Lee, Sung-Chul;Kim, Yun-Tae;Moon, Seong-Min;Hyun, Kyung-Yae;Kim, Dae-Sik;Choi, Seok-Cheol
    • Journal of Life Science
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    • v.18 no.11
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    • pp.1493-1498
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    • 2008
  • We defined factors affecting the postoperative outcome in adult cardiac surgery with cardiopulmonary bypass (CPB). Thirty-two adult patients scheduled for elective cardiac surgery participated in this study. Levels of leukocyte, glutamic oxaloacetic transaminase (GOT), troponin-I (cTNI), interleukin-6 (IL-6), D-dimer and neuron-specific enolase (NSE) were significantly elevated, whereas platelet count declined in cardiac surgery with CPB. GOT and D-dimer levels at CPB-off each had a positive significant correlation significantly with 24 hrs-bleeding, total bleeding, mechanical ventilatory assist time, ICU stay time and length of hospitalization. BUN levels at CPB-off were directly related to total bleeding, mechanical ventilatory assist time, ICU stay time and length of hospitalization. Platelet count at CPB-off was inversely related to mechanical ventilatory assist time, ICU stay time and length of hospitalization. Creatinine concentration at CPB-off interrelated positively with mechanical ventilatory assist time and ICU stay time. NSE levels at CPB-off had a positive relationship with postoperative 24 hrs-bleeding. The length of hospitalization was prolonged proportionally to the elevation of cTNI levels in cardiac surgery. Aortic cross-clamping and total CPB times also related with increase of 24 hrs and total bleeding volumes and the length of hospitalization. IL-6 and ET-1 had no mutual relation with any postoperative outcome. These data suggest that GOT, BUN, creatinine, D-dimer and platelet levels are the most important factors affecting postoperative outcomes and patient's recovery in adult cardiac surgery with CPB.

The Effects of Selenium on Cadmium-Induced Toxicity and Lipid Peroxidation in Rat Hepatocyte Primary Culture (랫드 간세포 일차배양에서 셀레늄이 카드뮴에 의해 유도된 독성 및 지질과산화에 미치는 영향)

  • Rhim, Tae-Jin
    • Korean Journal of Environmental Agriculture
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    • v.22 no.2
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    • pp.94-99
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    • 2003
  • The objective of present study was to investigate the antioxidative and hepatoprotective effects of selenium on cadmium-induced toxicity and lipid peroxidation in rat hepatocyte primary culture. To do this, two separate experiments were conducted. In Experiment 1, primary cultures of rat hepatocytes were incubated for 6 hr in the presence of various concentrations (1, 10, 50, 100, and $500\;{\mu}M$) of cadmium chloride. Cytotoxicity and lipid peroxidation were evaluated using the MTT assay and TBARS assay, respectively. Antioxidative and hepatoprotective effects were determined by measuring the activity of GOT and GSH-Px, respectively. Cell viability was reduced and lipid peroxidation was increased by cadmium in dose-dependent manners. There was significantly negative correlation (r=-0.943, p<0.01) between cell viability and lipid peroxidation GOT activity was increased and GSH-Px activity was decreased by cadmium at the concentration of $50\;{\mu}M$. In Experiment 2, primary cultures of rat hepatocytes were incubated for 6hr in the presence of 100\;{\mu}M$ of cadmium chloride and various concentrations (0.01, 0.1 and 1 ppm) of sodium selenite to assess the effect of selenium on cadmium-induced toxicity and lipid peroxidation. Cell viability and GSH-Px activity were increased by sodium selenite at the concentration of 1 ppm Whereas, lipid peroxidation and GOT activity were reduced by 0.1 ppm of sodium selenite. These results demonstrate that selenium has an antioxidative and hepatoprotective potentials against cadmium.

Relationship of the State of Smoking to Smoking Beliefs among College Students (일부 대학생의 흡연실태와 흡연신념과의 관련성)

  • Lee, Hyun-Ok;Song, Ji-Yeon
    • Journal of dental hygiene science
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    • v.13 no.4
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    • pp.369-377
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    • 2013
  • The purpose of this study was to examine the state of smoking among college students and the relationship between their state of smoking and smoking beliefs in an effort to provide information on the development and utilization of smoking-prevention and antismoking programs geared toward stepping up the health promotion of college students. The subjects in this study were 1,696 people at 10 different universities located in North Jeolla Province. A survey was conducted from May 1 to June 1, 2012, and the collected data were analyzed. The findings of the study were as follows: 1. Smoking status was as follows: smoking was 23.7% for students with experience, the first one when smoking was the highest 42.1% in high school and a four-year duration of smoking was highest in at least 46.1%. 2. As for smoking beliefs by general characteristics, the respondents whose monthly allowance was between 300 and 390 thousand Korean won and 400 thousand Korean won or more got 1.91 (p<0.001), Concerning the relationship between smoking and oral health, the biggest group that replied there was no relationship between the two got 2.00, which was the highest score (p<0.001). 3. Regarding the links between the state of smoking and smoking belief, the respondents who answered elementary school days in the time to begin smoking got 2.66, which was the highest score, and the one who answered four out of their five close friends were smoking got 2.60, which was the highest score (p<0.05). 4. As to the relationship of smoking dependence and intention of quitting smoking, the respondents who answered they were quite dependent on smoking got 2.75 (p<0.001), which was the highest score. And the respondents who answered they had no intention to give up smoking got 2.68, which was the highest score (p<0.01).