• Title/Summary/Keyword: GL-I

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Effect of Dietary Supplementation of the Combination of Gallic and Linoleic Acid in Thigh Meat of Broilers

  • Lee, Kyung-Haeng;Jung, Samooel;Kim, Hyun-Joo;Kim, Il-Suk;Lee, Jun-Heon;Jo, Cheorun
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.11
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    • pp.1641-1648
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    • 2012
  • This study was performed to investigate the combined effect of dietary supplementation of gallic and linoleic acid (GL) on the antioxidative effect and quality of thigh meat from broilers. Broilers received 3 dietary treatments: i) commercial finisher diet (control), ii) 0.5% GL (gallic:linoleic acid = 1 M:1 M), and iii) 1.0% GL during the 22 to 36 d. The pH value of broiler thigh meat was increased by GL supplementation. Water holding capacity of the thigh meat was enhanced by the 1.0% dietary GL supplementation. Antioxidative effect (total phenolic content, DPPH radical scavenging activity, $ABTS^+$ reducing activity, reducing power, and TBARS value) in the thigh from the broilers improved significantly with 1.0% GL. Linoleic acid and docosahexaenoic acids were higher in the broilers fed both levels of dietary GL. However, volatile basic nitrogen content and microbiological quality was not shown to be different between control and treated group. Results indicate that 1.0% dietary supplementation of GL can improve the antioxidant activity of broiler thigh meat and may enhance the meat quality.

사람의 Serine palmitoryl transferase II 및 ceramidase의 promoter에 대한 연구

  • Kim, Hui-Suk;Song, Seong-Gwang;Lee, Eun-Yeol;Lee, Sang-Do;Linn, Steve;Merrill, Alfred H.
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.588-591
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    • 2000
  • Serine palmitoyl transferase(SPT) and ceramidase are the key enzymes in sphingolipid biosynthesis. To study sphingolipid metabolism, we have got the 5'-upstream regions of human serine palmitoyl transferase subunit II and acid ceramidase gene by using GenomeWalker kits(Clontech Co.). Human genomic DNA was purified from HT29, human colon canser cell line by using DNAzol. We got several bands after secondary PCR and subcloned them to T7bule vector. Human SPTII promoter which we got was 2690bp but we cut it with Bgl II and vector with Bgl II and BamH I, and subcloned 1782bp to pGL2-enhancer vector and pGL2-basic vector with luciferase reporter gene. Human acid ceramidase promoter which we got were 2028bp and 1034bp and subcloned to pGL2-enhancer vector and pGL2-basic vector. We transfected these promoters to HT29 cell and assayed luciferase activity. For measuring transfection efficiency, pRL-TK vector with seapancy luciferase reproter gene was cotransfected with these promoters.

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Design and Implementation of Free-view Player using OpenGL and Nvidia Video Codec (OpenGL과 Nvidia 영상코덱을 사용한 실시간 자유시점 재생기 설계 및 구현)

  • Gu, Dongjun;Ahn, Heejune
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2020.11a
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    • pp.263-266
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    • 2020
  • 사용자에게 본인이 원하는 시점과 시각을 선택할 수 있도록 하는 자유시점 (Free Viewpoint) MPEG-I 과제를 통하여 3DOF, 3DOF+, 6DOF의 표준을 개발 중이다. 실사 영상의 자유시점 영상을 구현하는 방법으로는 깊이정보를 사용한 렌더링 기법을 사용하는데, 이를 실시간 재생할 수 있는 시스템은 개발되지 않았다. 본 논문에서는 PC 사양에서 NVIDIA 영상 코덱과 OpenGL사용하는 rtRVSlibrary를 바탕으로, 최대 8개의 HD급 다중 뷰 영상 입력 (컬러+깊이)을 자유 시점을 실시간 생성하여 디스플레이하는 재생기를 설계 및 개발하였다. 사용자는 원하는 시점으로 상하좌우앞뒤(회전)로 자유롭게 이동할 수 있으며, 계산양과 화질 효율성을 고려하여 디코딩한 입력영상 중에 두 개의 시점을 선별하는 알고리즘을 개발하여 실시간 동작 (25fps)을 검증하였다.

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Herbal Medicines Are Activated by Intestinal Microflora

  • Kim, Dong
    • Natural Product Sciences
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    • v.8 no.2
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    • pp.35-43
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    • 2002
  • Glycosides of herbal medicines, such as glycyrrhizin, ginsenosides, kalopanaxsaponins, rutin and ponicirin, were studied regarding their metabolic fates and pharmacological actions in relation to intestinal bacteria using germ-free, gnotobiotic and conventional animals. When glycyrrhizin (GL) was orally administered, $18{\beta}-glycyrrhetinic\;acid\;(GA)$, not GL, was detected in plasma and intestinal contents of gnotobiotic and conventional rats. However, GA could not be detected in germ-free rats. When GL was incubated with human intestinal bacteria, it was directly metabolized to GA (>95%) or via $18{\beta}-glycyrrhetinic\;acid-3-{\beta}-D-glucuronide$(>5%). Orally administered GL was effective in gnotobiotic and conventional rats for liver injury induced by carbon tetrachloride, but was not effective in germ-free rats. When ginseng saponins were orally administered to human beings, compound K in the plasma was detected, but the other protopanxadiol saponins were not detected. The compound K was active for tumor metastasis and allergy. When kalopanaxsaponins were incubated with human intestinal microflora, they were metabolized to kalopanaxsaponin A, kalopanaxsaponin I and hederagenin. These metabolites were active for rheumatoid arthritis and diabetic mellitus while the other kalopanxsaponins were not. When flavonoid glycosides were orally administered to animals, aglycones and/or phenolic acids were detected in the urine. The metabolic pathways proceeded by intestinal bacteria rather than by liver or blood enzymes. These metabolites, aglycones and phenolic acids, showed antitumor, antiinflammatory and antiplatelet aggregation activities. These findings suggest that glycosides of herbal medicines are prodrugs.

On the Mechanical Properties at Low Temperatures for Steels of Ice-Class Vessels (빙해선박용 강재의 저온특성에 관한 연구)

  • Min, Dug-Ki;Shim, Chun-Sik;Shin, Dong-Wan;Cho, Sang-Rai
    • Journal of the Society of Naval Architects of Korea
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    • v.48 no.2
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    • pp.171-177
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    • 2011
  • Tensile tests were conducted at low temperatures for the steel materials which are used for outer shell of the vessels making transit through the polar regions. The selected steel materials were GL-DH32, GL-DH36 and GL-EH36. In comparison with the results at room temperature, the yield stress increases approximately by 10 to 13 percent at $-30^{\circ}C$ and by 13 to 19 percent at $-50^{\circ}C$ while the tensile strength increases about by 9 percent at $-30^{\circ}C$ and 11 to 14 percent at $-50^{\circ}C$. To obtain true stress-true strain, i.e. correct plastic hardening characteristics, Bridgman's(1952) necking correction formula was introduced taking triaxial state of stresses after onset of diffuse necking into consideration. Photographs of fractured surfaces were taken by using Scanning Electron Microscope immedately after tensile tests completed and one for GL-EH36 has been presented in this paper.

Antidiabetic Effect of Glechoma longituba (Nakai) Kupr in Diabetic Rats induced by Streptozotocin (연전초(連錢草) 추출물이 Streptozotocin으로 유발시킨 흰쥐의 당뇨에 미치는 영향)

  • Lee, Kyung-Jin;Ham, In-Hye;Bu, Young-Min;Kim, Ho-Cheol;Choi, Ho-Young
    • The Korea Journal of Herbology
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    • v.23 no.3
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    • pp.175-180
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    • 2008
  • Objecitivies : While Glechoma longituba (Nakai) Kupr(GL) has been known as a antiinflammatory, antidiabetic and antihypertension medicine in korea traditional medicine, there has been only a few researches about it in Korea. Thus, we examined antidiabetic effect of GL in diabetic rats induced by streptozotocin Methods : To verify the effects of GL on serum glucose, creatinine, BUN, total cholesterol and triglyceride through streptozotocin-induced diabetic rats, some rats were injected 1 time with 55mg/kg streptozotocin intraperitoneally to induce diabetes, and other rats were injected with buffer I.P. as control group. Results : GL extracts significantly reduced the amount of serum glucose, BUN, creatinine, and triglyceride level in diabetics rats induced by streptozotocin. Conclusions : According to above result, Glechoma longituba was expected to be applied to the treatment of diabetes mellitus.

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Identification of the Hybrid Cluster Protein, HCP, from Amitochondriate Eukaryotes and Its Phylogenetic Implications

  • Han, Kyu-Lee;Yong, Tai-Soon;Ryu, Jae-Sook;Hwang, Ui-Wook;Park, Soon-Jung
    • Journal of Microbiology and Biotechnology
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    • v.14 no.1
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    • pp.134-139
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    • 2004
  • Hybrid cluster protein (HCP) was investigated because of its unique iron-sulfur clusters, which have been found in bacteria and archaea. Here, HCP homologous proteins from the third domain, 'eukarya'(3 amitochondriate protozoans, Giardia lamblia, Entamoeba histolytica, and Trichomonas vaginalis), were identified. All three amitochondriate protozoan HCPs (GlHCP, EhHCP, and TvHCP) belonged to Class I on the basis of two key characters, the cysteine spacing, Cys-(Xaa)₂Cys(Xaa)/sub 7-8/-Cys(Xaa)/sub 5/-Cys, and the absence of N-terminal deletion characteristic to the Class III. In phylogenetic analysis performed with amino acid sequences of 3 eukaryal, 5 bacterial, and 4 archaeal HCPs, the maximum likelihood (ML) tree indicated that TvHCP was clustered with Class I HCPs, whereas the other two HCPs (GlHCP and EhHCP) formed an independent clade with a high bootstrapping value (96%) not belonging to any previously recognized HCP class. In spite of the relatively lower bootstrapping value (61%), the position of the new eukaryal GlHCP-EhHCP clade was close to Class I, including the TvHCP, and Classes II and III were closely related with each other. The finding of eukaryal HCPs would help to understand the evolutionary history of HCP.

A Design of Programmable Fragment Shader with Reduction of Memory Transfer Time (메모리 전송 효율을 개선한 programmable Fragment 쉐이더 설계)

  • Park, Tae-Ryoung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.12
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    • pp.2675-2680
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    • 2010
  • Computation steps for 3D graphic processing consist of two stages - fixed operation stage and programming required stage. Using this characteristic of 3D pipeline, a hybrid structure between graphics hardware designed by fixed structure and programmable hardware based on instructions, can handle graphic processing more efficiently. In this paper, fragment Shader is designed under this hybrid structure. It also supports OpenGL ES 2.0. Interior interface is optimized to reduce the delay of entire pipeline, which may be occurred by data I/O between the fixed hardware and the Shader. Interior register group of the Shader is designed by an interleaved structure to improve the register space and processing speed.

Prediction Model of Software Size for 4GL and Database Projects

  • Yoon, myoung-Young
    • Journal of Korea Society of Industrial Information Systems
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    • v.4 no.3
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    • pp.1-7
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    • 1999
  • An important task for any software project manager is to be able to predict and control project size. Unfortunately, there is comparatively little work that deals with the problem of building prediction methods for software size in fourth-generation languages and database projects. In this paper, we propose a new estimation method for estimating for software size based on minimum relative error(MRE) criterion. The characteristic of the proposed method is insensitive to the extreme values of the observed measures which can be obtained early in the development life cycle. In order to verify the performance of the proposed estimation method for software size in terms of both quality of fit and predictive quality, the experiments has been conducted for the dataset Ⅰ and Ⅱ, respectively. For the data set Ⅰ and Ⅱ, our proposed prediction method was shown to be superior to the traditional method LS and RLS in terms of both the quality of fit and predictive quality when applied to data obtained from actual software development projects.

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Using Arduino and Processing Graphics performance validation (아두이노와 Processing을 사용한 그래픽 성능 검증)

  • Choi, Chul-kil;Lee, Sung-jin;Lee, Kyung-mu;Choi, Byeong-yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.05a
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    • pp.975-977
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    • 2013
  • Arduino is for design based on open source prototyping platform, artist, designer, hobby activists, etc, i has been designed for all those who are interested in the environment construct. Arduino adventage you can easily create applications hardware, without deep knowledge about the hardware. Configuration of arduino using AVR microcontroller ATmage 168, software to action arduino using arduino program, MATLAB, Processing. Arduino is open source base, you can hardware production directly and using shield additionally, the arduino can be combined. Processing iis open source. You can 2D, 3D, PDF output, using P3D and OpenGL graphics. Also you can check by running a stand-alone application. Through a combination of Arduino, library support, such as sound, video, and computer vision can be expanded, this program is the Android phone and iPhone programming. In this paper, sortware was used for Processing, hardware was used for arduino MegaADK board, After making easy 2axis game, using the software and hardware verification.

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