• Title/Summary/Keyword: GEORGI

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A Pharmacognostical Study on the 'Man Byung Cho' (만병초의 생약학적 연구)

  • Park, Jong-Hee;Kim, Jin-Soo;Jeong, Ae-Yeong;Namba, Tsuneo
    • Korean Journal of Pharmacognosy
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    • v.26 no.2
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    • pp.168-174
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    • 1995
  • Korean folk medicine 'Man Byung Cho' has been used to cure abdominal pain, athlete's foot and neuralgia. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'Man Byung Cho', the leaf morphology and anatomy were examined for the Korean species of Rhododendron subgenus Hymenanthes, such as R. brachycarpum G. Don, R. brachycarpum var. rosueum Koidz. and R. aureum Georgi. The study shows that 'Man Byung Cho' is the leaf of R. brachycarpum and R. brachycarpum var. roseum.

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A Platform for RFID Security and Privacy Administration

  • Rieback, Melanie R.;Gaydadjiev, Georgi N.;Crispo, Bruno;Hofman, Rutger F.H.;Tanenbaum, Andrew S.
    • 한국정보컨버전스학회:학술대회논문집
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    • 2008.06a
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    • pp.75-86
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    • 2008
  • This paper presents the design, implementation, and evaluation of the RFID Guardian, the first-ever unified platform for RFID security and privacy administration. The RFID Guardian resembles an "RFID firewall", enabling individuals to monitor and control access to their RFID tags by combining a standard-issue RFID reader with unique RFID tag emulation capabilities. Our system provides a platform for coordinated usage of RFID security mechanisms, offering fine-grained control over RFID-based auditing, key management, access control, and authentication capabilities. We have prototyped the RFID Guardian using off-the-shelf components, and our experience has shown that active mobile devices are a valuable tool for managing the security of RFID tags in a variety of applications, including protecting low-cost tags that are unable to regulate their own usage.

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ON THE THEORY OF LORENTZ SURFACES WITH PARALLEL NORMALIZED MEAN CURVATURE VECTOR FIELD IN PSEUDO-EUCLIDEAN 4-SPACE

  • Aleksieva, Yana;Ganchev, Georgi;Milousheva, Velichka
    • Journal of the Korean Mathematical Society
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    • v.53 no.5
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    • pp.1077-1100
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    • 2016
  • We develop an invariant local theory of Lorentz surfaces in pseudo-Euclidean 4-space by use of a linear map of Weingarten type. We find a geometrically determined moving frame field at each point of the surface and obtain a system of geometric functions. We prove a fundamental existence and uniqueness theorem in terms of these functions. On any Lorentz surface with parallel normalized mean curvature vector field we introduce special geometric (canonical) parameters and prove that any such surface is determined up to a rigid motion by three invariant functions satisfying three natural partial differential equations. In this way we minimize the number of functions and the number of partial differential equations determining the surface, which solves the Lund-Regge problem for this class of surfaces.

Baicalein and Baicalin as Inhibitors of HIV-1 Integrase (면역결핍바이러스 인테그라제 억제제로서 Baicalein과 Baicalin)

  • 이민전;김미라;이용섭;신차균
    • YAKHAK HOEJI
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    • v.47 no.1
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    • pp.46-51
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    • 2003
  • Baicalein and baicalin are flavonoid compounds isolated from medicinal herb Scutellaria baicalensis Georgi (Labiatae) and have been known to possess antiviral activities. In the present study, we investigated the in vitro effects of baicalein and baicalin on the three distinctive enzymatic activities of the human immunodeficiency virus type-1 (HIV-1) integrase-endonucleolytic, integration, and disintegration activities. Both compounds inhibited the three enzymatic activities in a dose-dependent manner. The 50% inhibitory concentrations of baicalein and baicalin for endonucleolytic activities of HIV-1 integrase were 4.4$\pm$3.3 and 25.9$\pm$4.0$\mu$M, respectively. In general, baicalein exhibited nearly 6- to 10-fold stronger inhibition than baicalin for the three enzymatic activities. These data demonstrate that baicalein or baicalin can be used as a leading compound to develop anti-AIDS chemotherapeutic agents targeting to the HIV-1 integrase.

The Effects of Scutellaria baicalensis and Scutellaria baicalensis metabolite on Anxiety in the Elevated Plus-Maze in Rats

  • Jung, Ji-Wook;Ahn, Nam-Yoon;Oh, Hye-Rim;Park, Sung-Hwan;Oh, Jin-Kyung;Lee, Bo-Kyung;Kim, Dong-Hyun;Ryu, Jong-Hoon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.211.3-212
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    • 2003
  • Scutellaria baicalensis Georgi is one of the most important medicinal herbs in traditional chinese medicine. The object of this study was to determine the effects of water extracts of Scutellaria baicalensis (SB) and Scutellaria baicalensis metabolite (SBM) on the anxiolytic-like activities in the elevated plus-maze (EPM) test. The water extracts of SB (100, 200, or 400 mg/kg), and SBM (100 mg/kg) were orally administered to male SD rats for 3 day. All rats were subjected to behavioral tests for the anxiolytic activity at 3 days. (omitted)

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Taxonomic notes and distribution of Gueldenstaedtia (Chesneyinae, Fabaceae) in Mongolia

  • BAASANMUNKH, Shukherdorj;OYUNTSETSEG, Batlai;TSEGMED, Zagarjav;ILLARIONOVA, Irina D.;NYAMBAYAR, Nyamjantsan;CHOI, Hyeok Jae
    • Korean Journal of Plant Taxonomy
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    • v.52 no.1
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    • pp.64-70
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    • 2022
  • The genus Gueldenstaedtia Fisch. is small genus of Fabaceae that includes four species worldwide. Among these, G. monophylla Fisch and G. verna (Georgi) Boriss. are currently recognized as occurring in Mongolia. Here, we present our findings on G. verna from our recent field surveys in eastern Mongolia in 2020. Gueldenstaedtia monophylla is mostly distributed in the western region, whereas G. verna occurs in eastern Mongolia. The regional conservation status of both species was assessed as near threatened based on criterion B in the country. We provided descriptions, grid distribution maps, taxonomic notes and photographic illustrations of the two species based on our newly collected samples.

Antioxidant Activities of Medicinal Plant Extracts (약용식물 추출물의 항산화 효과)

  • Joo, Shin Youn
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.4
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    • pp.512-519
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    • 2013
  • The antioxidant activities of ethanolic extracts obtained from medicinal plants (Scutellaria baicalensis Georgi, Acanthopanax sessiliflorum Seeman, Pueraria lobata Ohwi, Portulaca oleracea Linne, Crataegus pinnatifida Bunge var. typica Schneider, Euonymus alatus Apterus, Hovenia dulcis Thunberg, Prunus yedoensis Matsumura, Albizzia julibrissin Durazz., Chrysanthemum indicum Linne) were evaluated for total phenolic content, total flavonoid content, DPPH radicals, nitrites, $Superoxide^-$ radicals, $ABTS^+$ radical scavenging activity, and reducing power. Antioxidant capacities were the highest in Prunus yedoensis Matsumura for DPPH radical scavenging activity ($IC_{50}$ $5.39{\mu}g/mL$), reducing power (2.72, $A_{700}$), and nitrite scavenging activity ($IC_{50}$ $167.94{\mu}g/mL$). Hovenia dulcis Thunberg and Acanthopanax sessiliflorum Seeman were effective for their nitrite scavenging activities (over 90% at 1 mg/mL). The $Superoxide^-$ radical scavenging activity of Prunus yedoensis Matsumura ($IC_{50}$ $43.39{\mu}g/mL$) was stronger than tannic acid ($IC_{50}$ $46.51{\mu}g/mL$). Five samples (Prunus yedoensis Matsumura, Acanthopanax sessiliflorum Seeman, Hovenia dulcis Thunberg, Crataegus pinnatifida Bunge var. typica Schneider, Scutellaria baicalensis Georgi) were effective for their $ABTS^+$ radical scavenging activity (more than 90% at 0.5 mg/mL). These results suggest that the ethanolic extracts of Prunus yedoensis Matsumura could be used as a functional ingredient in food products.

Effects of Baikal Skullcap (Scutellaria baicalensis Georgi) extracts on the recovery of liver function in $CCl_4$-exposed rats (황금 추출물이 $CCl_4$ 중독 쥐의 간장기능 회복에 미치는 영향)

  • Lim, Sang-Cheol
    • Korean Journal of Plant Resources
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    • v.23 no.1
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    • pp.54-59
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    • 2010
  • The objective of present study was to investigate the effect of Baikal Skullcap (Scutellaria baicalensis Georgi) extracts on recovery of liver function in $CCl_4$-exposed rats. The values of RBC, Hb and PCV did not show significant difference among all treatment groups. The counts of WBC was lower in Skullcap extracts groups than in control group. The ratio of neutrophils and eosinophiles were decreased, and the ratio of lymphocytes and monocytes were increased with increased administration of Skullcap extracts dosage. The ratio of basophils was, however, not significantly different among all treatment groups. The concentration of plasma total protein and albumin showed no significant difference among all treatment groups. The ratio of albumin/globulin was higher in Skullcap extracts groups than in control group. The activities of GOT, GPT and LDH were lower in Skullcap extracts groups, compared to control group. The liver IL-$1{\beta}$, IL-6 and TNF-$\alpha$ concentration were decreased, and IL-10 was increased in Skullcap extract groups, compared to control group. Results of this study suggested that Skullcap may alleviate liver inflammatory reaction induced by liver toxicity.

Cryopreservation of Scutellaria baicalensis Cells by Two-step Cooling Method

  • Seo, Weon-Taek;Kim, Suk-Weon;Liu, Jang-Ryol;Kim, Ik-Hwan;Park, Young-Hoon;Choe, Tae-Boo
    • Journal of Microbiology and Biotechnology
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    • v.6 no.3
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    • pp.209-212
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    • 1996
  • A two-step cooling technique has been developed for cryopreservation of suspension cultured Scutellaria baicalensis cells. Efficient regrowth of cryopreserved cells was obtained in cryoprotected cells with a mixture of 1.5 M glycerol and 0.4 M sucrose in Schenk and Hildebrandt medium without pretreatment in high osmotic medium. Optimum freezing conditions were found to be a cooling rate of $0.5^{\circ}C$ min from $4^{\circ}C$ to $-40^{\circ}C$, and then retaining samples at $-40^{\circ}C$ for 30 min prior to plunging into liquid nitrogen. A regrowth rate of approximately 95$%$ was obtained after three month storage in liquid nitrogen. Callus cultures established from the cryopreserved cells were found to produce the same patterns of flavonoid accumulation and retain their baicalin producing activity.

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Mixed double-embryo transfer: A promising approach for patients with repeated implantation failure

  • Stamenov, Georgi Stamenov;Parvanov, Dimitar Angelov;Chaushev, Todor Angelov
    • Clinical and Experimental Reproductive Medicine
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    • v.44 no.2
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    • pp.105-110
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    • 2017
  • Objective: The purpose of this study was to evaluate the efficacy of frozen mixed double-embryo transfer (MDET; the simultaneous transfer of day 3 and day 5 embryos) in comparison with frozen blastocyst double-embryo transfer (BDET; transfer of two day 5 blastocysts) in patients with repeated implantation failure (RIF). Methods: A total of 104 women with RIF who underwent frozen MDET (n = 48) or BDET (n = 56) with excellent-quality embryos were included in this retrospective analysis. All frozen embryo transfers were performed in natural cycles. The main outcome measures were the implantation rate, clinical pregnancy rate, multiple pregnancy rate, and miscarriage rate. These measures were compared between the patients who underwent MDET or BDET using the chi-square test or the Fisher exact test, as appropriate. Results: The implantation and clinical pregnancy rates were significantly higher in patients who underwent MDET than in those who underwent BDET (60.4% vs. 39.3%, p=0.03 and 52.1% vs. 30.4%, p=0.05, respectively). A significantly lower miscarriage rate was observed in the MDET group (6.9% vs. 10.7%, p=0.05). In addition, the multiple pregnancy rate was slightly, but not significantly, higher in the MDET group (27.1% vs. 25.0%). Conclusion: MDET was found to be significantly superior to double blastocyst transfer. It could be regarded as an appropriate approach to improve in vitro fertilization success rates in RIF patients.