• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.352-355
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• 2002

The purpose of this study was to investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the mortor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the somatomotor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients.

• 한국임상수의학회지
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• 제21권4호
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• pp.380-383
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• 2004

Two dogs with hindlimb paralysis were referred to the Teaching Animal Hospital of Chonbuk National University. We performed an acupuncture in two cases. Case No.1 was a 5-year-old, 3kg intact mixed breed female dog presented with hindlimb paralysis during last 3 days. Physical examinations, CBC, serum chemistry, urinalysis and radiography carried out. The diagnosis was the thoracolumbar disk disease of Tl2-Tl3 on the basis of above these tests. Acupoints selected were Lumbosacral point, GV-5(Xuan Shu), GV-20(Bai Hui), GB-30(Huan Tiao), GB-31(Feng Shi), ST-36(Zu San Li) and GB-34(Yang Ling Quan). we performed an acupuncture therapy five times at 2 days intervals for 15 minutes each time. Case No.2 was 7-year-old, 6.0kg, mixed breed male dog which was presented with the history of hindlimb paralysis since 2 months. The medical history of the patient revealed that the condition did not respond to medicinal therapy. The diagnosis was the thoracolumbar disk disease of Tl3-Ll and left patellar luxation (one or two grade). We decided to perform acupuncture in this case also and the Lumbosacral point, GV-5(Xuan Shu), GV­6(Ji Zhong), GV-7(Zhong She), GB-30(Huan Tiao), GB-31(Feng Shi), ST-36(Zu San Li), GB-34(Yang Ling Quan) were used. We performed acupuncture therapy at day 3, 6, 8 and 10 for 15 minutes each time. The response to an acupuncture therapy in two patients was good and the patients were almost recovered from hindlimb paralysis.

• Korean Journal of Acupuncture
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• 제20권3호
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• pp.9-27
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• 2003

Objectives : The aim of this study was to examine the effects of electro-acupuncture(EA) at the SP6(Sameumgyo)-GB39(Hyeonjong) on normal human EEG using power spectral analysis. Methods : EEG power spectrum exhibit site-specific and state-related differences in specific frequency bands. In this study, power spectrum was used as a measure of complexity(LAXTHA Co., KOREA). 30 channel EEG study was carried out in 20 subjects $(20\;males;\;age=21.4{\pm}0.5\;years)$. Results : In $\alpha$(alpha) band, the power values at F4 channels(p<0.05) during the SP6-GB39 acupoints treatment was significantly increased. But, the power values at Fz channel during the non-acupoint treatment was significantly decreased . In $\beta$(beta) band, the power values at Fz, FTC1, T3 channels(p<0.05) was significantly increased during the SP6-GB39 acupoints treatment. In $\delta$(delta) band, the power values at F4, C3, Cz, CP1, Pz channels(p<0.05) during SP6-GB39 acupoints treatment were significantly decreased.

• 동의생리병리학회지
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• 제19권4호
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• pp.1032-1038
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• 2005

Using the 2-channel DROS SQUID (Korea Research Institute of Standards of Science, 1999), the present study was carried out to record changes elicited in the auditory cortex by acupuncture stimulus (right GB43, Xiaxi). Needle-retention and manual needle-twitching stimulation of GB43 and SP1 were done for acquiring the brain activities changed by acupuncture. Acupoint GB43 is known to be effective for the treatment of ear-related disease, such as deafness and tinnitus, and to be suspected to be related to the auditory cortex. Auditory evoked magnetic fields were recorded from the left hemisphere of five or four subjects, in response to contralateral ear stimulation by irregularly spaced 170msec long 1kHz tone busts (Korea Research Institute of Standards of Science). The result as follows The latency and amplitude of SQUID MEG responses at the human auditory cortex changed by needle-retention condition on GB43 were 7.2msec and 1.617, respectively, which were slower and larger than those of no-acupuncture condition. The amplitude of SQUID MEG responses at the human auditory cortex changed by needle-twitching condition on GB43 was 13.517, which was larger than that of no-acupuncture condition. The change in SP1 following GB43 needle-twitching condition were not observed in latency. The amplitude changed by needle-twitching condition on SP1 was 12.2fT, which was not significant. These results suggested that auditory cortex can be affected by acupuncture stimulus, though not specific or significant because of small number of subjects.

• 대한약침학회지
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• 제8권1호
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• pp.5-11
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• 2005

Objectives : This study has been designed and performed to identify the effect of Hominis Placenta herbal acupuncture which is usually used in reducing sleep pattern disturbances. Methods : The study subjects studied included 48 patients who were admitted in hospital located in Pusan, and they were classified into 2 groups : 25 patients in the experimental group who injected Hominis Placenta herbal acupuncture and 23 patients in the control group who were treated by acupuncture. The both group injected on $GB_{20}$, $GB_{12}$ and $GB_{20}$ for 5 days without medicine. The sleep pattern disturbance score was measured by using 15 questions according to Korean Sleep Scale A(Oh, Jin Joo. Song, Mi. Soon. Kim, Shin Mi. 1998). Results & conclusions : The sleep pattern disturbance score of the experimental group who injected Hominis Placenta herbal acupuncture was significantly lower than that of the control group(t=7.00 p=.00). These results provided that Hominis Placenta herbal acupuncture of $GB_{20}$, $GB_{12}$ and HT, was effective for relieving sleep pattern disturbances, it is need mere sample's number and more treatment's duration.

• ETRI Journal
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• 제31권6호
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• pp.749-754
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• 2009

The design and performance of an InGaAs/InP transimpedance amplifier and post amplifier for 40 Gb/s receiver applications are presented. We fabricated the 40 Gb/s transimpedance amplifier and post amplifier using InGaAs/InP heterojunction bipolar transistor (HBT) technology. The developed InGaAs/InP HBTs show a cut-off frequency ($f_T$) of 129 GHz and a maximum oscillation frequency ($f_{max}$) of 175 GHz. The developed transimpedance amplifier provides a bandwidth of 33.5 GHz and a gain of 40.1 $dB{\Omega}$. A 40 Gb/s data clean eye with 146 mV amplitude of the transimpedance amplifier module is achieved. The fabricated post amplifier demonstrates a very wide bandwidth of 36 GHz and a gain of 20.2 dB. The post-amplifier module was fabricated using a Teflon PCB substrate and shows a good eye opening and an output voltage swing above 520 mV.

• Journal of Acupuncture Research
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• 제25권5호
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• pp.59-68
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• 2008

Objectives : The purpose of this study is to investigate the effects of $GB_{41}$ supplementation and $BL_{66}$ draining on changes in cerebral blood flow in normal rats. Methods : Regional cerebral blood flow(rCBF) and mean arterial blood pressure(MABP) in normal rats are observed, and those mechanisms were also investigated with pre-treatment of indomethacin(IDM) and methylene blue(MTB) each. Results : In this study, $GB_{41}$ supplementation and $BL_{66}$ draining elevated rCBF in time-dependent manner. Pre-treatment with indomethacin(IDM), an inhibitor of cyclooxygenase, inhibited increase of rCBF effectively. But pre-treatment with methylene blue(MTB), an inhibitor of guanylate cyclase, didn't affect rCBF levels. In addition, pre-treatment with IDM also decreased MABP levels. Conclusions : In conclusion, these results suggest that $GB_{41}$ supplementation and $BL_{66}$ draining is effective to increase rCBF, and the mechanisms are thought to be related to cyclooxygenase pathways.

• 암석학회지
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• 제11권1호
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• pp.1-16
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• 2002

1/5만 포천-기산리도폭에 넓게 분포하는 쥬라기의 대보화강암류는 선캠브리아기의 편마암 복합체를 관입한다. 이들은 모우드 분석결과 거의가 몬조화강암에 해당하며, 구성광물특성상 흑운모화강암(Gb), 석류석흑운모화강암(Ggb) 그리고 복운모화강암(Gtm)으로 구분된다. 주변지역의 야외조사와 K-Ar 운모류 연령해석에 의하면 Ggb가 Gb를 관입하였으며 Gtm은 가장 후기로 해석된다. 연구대상인 Gb와 Ggb는 서브알카린과 캘크알칼린 계열의 산성암류이다. $SiO_2$ 증가에 따라 주 원소의 대부분이 완만한 부의 경향을 뚜렷히 가지나, $TiO_2$, MgO 및 CaO등은 두 개의 다소 다른 선상분포를 이룬다. 이와 더불어 선상의 분포경향을 이룬 AMF, Sr대 Ba 그리고 Rb-Ba-Sr 관계 등으로 미루어, 이들은 동일마그마에서 기원되었으며 Ggb가 Gb보다 분화후기의 산물로 해석된다. Sr 대 CaO와 Sr 대 $K_2O$는 모두 정의 관계를 이루나, Sr이 알칼리장석보다 사장석의 분별결정작용에 보다 더 관여한 경향을 이룬다. 콘드라이트 값으로 표준화한 변화도에서 이들은 LREE에서 HREE로 갈수록 점진적으로 뚜렷이 결핍된다. 그러나 Ggb의 한 개 시료는 HREE가 점이적 증가경향을 이루며, 이는 석류석의 수반에 의한 것으로 해석된다. Eu 부의 이상으로 미루어 Gb에 비해 Ggb에서 사장석의 분별결정작용이 매우 강하게 일어난 것으로 보인다. (Qz+Af) 대 Op의 모우드 상관도에서 Gb는 거의가 자철석 계열에, Ggb는 모두 티탄철석 계열에 속한다. 모우드 분석과 대자율 역산에서 Gb와 Ggb의 대자율은 각각 339.3 ${\mu}SI$와 2.3 ${\mu}SI$로써 뚜렷이 구분되며, 이는 각각 자철석과 흑운모가 주도하는 것으로 분석된다 Gb와 Ggb의 $SiO_2$는 각각 높은 함량과 좁은 범위값을, $K_2O/Na_2O$는 각각 1.29와 1.27을, 그리고 A/CNK 몰비는 거의가 1.05 이상의 값을 가진다. 그 밖에 ACF도와 대자율값에서도 모두 S-형에 속하는 암석성인적 특성을 보인다.

• Nutrition Research and Practice
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• 제9권4호
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• pp.439-444
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• 2015

BACKGROUND/OBJECTIVES: This study was conducted to investigate the effects of fermented soybean (FS) extract on adipocyte differentiation and fat accumulation using cultured 3T3-L1 adipocytes. MATERIALS/METHODS: 3T3-L1 adipocytes were treated with FS and nonfermented soybean (NFS) extract during differentiation for 10 days in vitro. Oil red O staining was performed and glycerol-3-phosphate dehydrogenase (GPDH) activity was measured for analysis of fat accumulation. Expressions of adipogenic genes were measured. RESULTS: Soluble extract of soybean fermented with Aspergillus oryzae GB107 contained higher levels of low-molecular-weight protein than conventional soybean protein did. FS extract ($50{\mu}g/ml$) inhibited adipocyte differentiation and fat accumulation during differentiation of 3T3-L1 preadipocytes for 10 days in vitro. Significantly lower GPDH activity was observed in differentiated adipocytes treated with the FS extract than those treated with NFS extract. Treatment with FS extract resulted in decreased expression levels of leptin, adiponectin, and adipogenin genes, which are associated with adipogenesis. CONCLUSIONS: This report is the first to demonstrate that the water-soluble extract from FS inhibits fat accumulation and lipid storage in 3T3-L1 adipocytes. Thus, the soybean extract fermented with A. oryzae GB107 could be used to control lipid accumulation in adipocytes.

• 패션비즈니스
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• 제12권5호
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• pp.24-38
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• 2008

As an attempt to improve the seaming of clothes exported to China, this study is intended to strengthen the clothing industry in Korea by providing data on the body figures of Chinese women. Direct measurement was conducted on 193 women aged 19-24 residing in Shanghai, China. Then we classified and identified the body types and characteristics of Chinese women based on the drop values suggested by the National Standard of the People's Republic of China(GB/T 1335.2-1997). The following is a summary and conclusion of this study. 1. The following results were obtained by measuring the body sizes of women aged 19-24 living in Shanghai, China. 2. After having conducted a factor analysis on 111 body measurement items, 15 index items, and 11 calculation items, we were able to deduce a total of 6 factors. 3. We categorized the body types of 19-24 year-old women living in Shanghai, China according to the drop values suggested by GB/T 1335.2-1997 where D-type was added to Y, A, B, and C-types for a total of 5 categories. The characteristics of each body type following the body type structure factor are Y-type for slender type, A-type for standard type, B-type for slightly large type, and C-type for obese type.