• Title/Summary/Keyword: GAP43

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Feasibility Study for College of Medicine Establishment in Western Region of Chungcheongnam-do (충청남도 서부권 의과대학 설립에 대한 타당성 연구)

  • Kim, Jeong-Koo;Lee, Young-Shin;Kim, Woong-Yi;Yi, Jin-Bok
    • Journal of radiological science and technology
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    • v.43 no.4
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    • pp.289-295
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    • 2020
  • This study investigated the feasibility of establishing a college of medicine in the western region of Chungnam to fill the gap in the medical doctor in charge of essential medical care in the region. Currently, the level of medical services in Chungnam is low compared to provinces across the country and in particular, 7 cities and towns, which account for 760,000 people, one-third of Chungnam's population, are located in the western regions of Chungnam. Because of this, in the event of an emergency patients, it is necessary to travel to Cheonan, Daejeon, Seoul, etc. where the regional emergency medical center is located for more than 1 hour and 30 minutes. In the case of critically ill and emergency patients transfer, it is a situation that misses the golden time and causes valuable loss of life. In order to improve the medical environment in the western region of Chungnam and improve the lives of residents in vulnerable areas of medical services, it is believed that establishing a college of medicine in the western region of Chungnam is essential.

Direct treatment on live and cancer cells & process innovation of bio-sensor using atmospheric pressure plasma system with low-temperature arc-free unit

  • Lee, Keun-Ho;Lee, Hae-Ryong;Jun, Seung-Ik;Bahn, Jae-Hoon;Baek, Seung-J.
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.43-43
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    • 2010
  • We have characterized the parametric and functional properties of live cell and cancer cell according to plasma treatment conditions using Atmospheric Pressure (AP) Plasma with uniquely designed low temperature arc-free unit. AP plasma system showed very highly efficient capabilities of reacting and interfacing directly with live and cancer cells. The parametric results with the types of gases, applied power, applied gap, and process times on cells will be presented in accordance with functional studies of the works. The growth of cancer cells is directly influenced by AP plasma exposure with evaluating plasma conditions in several human cancer cells and understanding how plasma exposure alters molecular signaling pathways. The cells exhibit a slower or faster growth rates compared with untreated cells, depending on the cell types. These results strongly support the conclusion that alterations in one or more of each gene are responsible, at least in part, for plasma-induced apoptosis in cancer cells. In addition, it also will be presented that AP plasma has an important role for the improvement of sensor performance due to excellent interface property between enzyme and metal electrode for bio sensor manufacturing process.

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A Study on the Extraction of Living SOC Deficient Areas in Small and Medium Cities Using Big Data - Focused on Iksan-si, Jeollabuk-do - (빅데이터를 활용한 중소도시의 생활SOC 결핍지역 추출 연구 - 전라북도 익산시를 중심으로 -)

  • Han, Da-Hyuck;Kim, Dong-Woo;Lee, Min-Seok
    • Journal of the Korean Institute of Rural Architecture
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    • v.22 no.4
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    • pp.43-50
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    • 2020
  • The purpose of this study is to extract deficiency areas as basic data of policies and projects in the future Living SOC introduction and planning. In order to extract living SOC deficient areas, accessibility data for living SOC and density data for main users by facility were overlapped, focusing on the living SOC indicators presented in the National Urban Regeneration Basic Policy. According to the analysis of accessibility of the Iksan-si Living SOC, the gap between deficiency in urban and township areas was large in common with the accessibility of the village and local base units. As a result of overlapping life SOC accessibility data and density data analysis of the main users by facility, areas where accessibility is weak but not inhabited by the main users of each facility were extracted. It is meaningful that more accurate deficient areas can be extracted by simultaneously utilizing the density distribution of the main users, rather than simply accessing the facilities.

Video Learning Enhances Financial Literacy: A Systematic Review Analysis of the Impact on Video Content Distribution

  • Yin Yin KHOO;Mohamad Rohieszan RAMDAN;Rohaila YUSOF;Chooi Yi WEI
    • Journal of Distribution Science
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    • v.21 no.9
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    • pp.43-53
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    • 2023
  • Purpose: This study aims to examine the demographic similarities and differences in objectives, methodology, and findings of previous studies in the context of gaining financial literacy using videos. This study employs a systematic review design. Research design, data and methodology: Based on the content analysis method, 15 articles were chosen from Scopus and Science Direct during 2015-2020. After formulating the research questions, the paper identification process, screening, eligibility, and quality appraisal are discussed in the methodology. The keywords for the advanced search included "Financial literacy," "Financial Education," and "Video". Results: The results of this study indicate the effectiveness of learning financial literacy using videos. Significant results were obtained when students interacted with the video content distribution. The findings of this study provide an overview and lead to a better understanding of the use of video in financial literacy. Conclusions: This study is important as a guide for educators in future research and practice planning. A systematic review on this topic is the research gap. Video learning was active learning that involved student-centered activities that help students engage with financial literacy. By conducting a systematic review, researchers and readers may also understand how extending an individual's financial literacy may change after financial education.

A Study on the Cause and Improvement of Crack in the Installing Structure of the Bulkhead of Aircraft (항공기 Bulkhead 체결구조의 균열 원인 및 개선에 관한 연구)

  • Choi, Hyoung Jun;Park, Sung Jae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.448-454
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    • 2020
  • This study aims to determine the cause of structural defects occurring during aircraft operations and to verify the structural integrity of the improved features. The fracture plane was analyzed to verify the characteristics of the cracks and the fatigue failure leading to the final fracture was determined by the progress of the cracks by the repeated load. During aircraft operations, the comparative analysis of the load measurement data at the cracks with the aircraft design load determined that the measured load was not at the level of 30% of the design to be capable of being damaged. A gap analysis resulted in a significant stress of approximately 32 ksi at the crack site. Pre-Load testing also confirmed that the M.S. was reduced by more than 50% from +0.71 to +0.43, resulting in a sharp increase in aircraft load and the possibility of cracking when combined. Thus, structural reinforcement and the removal of the gap for aircraft cracking sites improved the defect. Based on the structural strength analysis of the improvement features, the bulkhead has a margin of about +0.88 and the fitting feature is about +0.48 versus allowable stress. In addition, the life analysis results revealed an improvement of approximately 84000 hours.

IN VITRO MARGINAL FIT OF THE COMPUTERAIDED MILLED CERCON CROWNS

  • Chang, Jae-Yoon;Yang, Jae-Ho;Han, Jung-Suk;Lee, Jai-Bong
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.3
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    • pp.306-313
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    • 2005
  • Statement of problem. There have been many studies about marginal discrepancy of single restorations made by various systems and materials. But most of statistical inferences are not definite because of sample size, measurement number, measuring , instruments, etc. And there have been few studies about the marginal fit of Computer-aided Cercon crowns. Purpose. The purpose of this study was to compare the marginal fit of the anterior single restorations made using computer-aided milled Cercon crowns with metal-ceramic restorations and to obtain more accurate information by using a large enough sample size and by making sufficient measurements per specimen. Material and methods. The in vitro marginal discrepancies of computer-aided milled Cercon crowns and control groups (metal ceramic crowns) were evaluated and compared. The crowns were made from one extracted maxillary central incisor prepared by milling machine. 30 crowns per each system were fabricated. Measurements of a crown were recorded at 50 points that were randomly selected for marginal gap evaluation. Parametric statistical analysis was performed for the results. Results. The means and standard deviations of the marginal fit were 85$\pm$22$\mu$m for the control group and 91$\pm$15$\mu$m for the Cercon crowns. The t-test of the marginal discrepancies between Cercon crowns and metal-ceramic crowns were performed. Significant differences were not found between groups (P=0.230>.05). Based on the criterion of 120$\mu$m as the limit of clinical acceptability, the mean marginal fits of Cercon crowns and metal-ceramic crowns were acceptable. Conclusion. Within the limitations of this in vitro study, the following conclusions were drawn: 1. Mean gap dimensions and standard deviations at the marginal opening for maxillary incisal crowns were 85$\pm$22$\mu$m for the control (metal-ceramic crowns), 91$\pm$15$\mu$m for Cercon crowns. 2. The Cercon crowns showed slightly larger marginal gap discrepancy than the control but marginal gap between Computer-aided milled Cercon crowns and metal ceramic crowns did not showed significant difference (P>.05). 3. The Cercon crowns and metal ceramic crowns showed clinically acceptable marginal discrepancy.

Synthesis and Photovoltaic Properties of Alternating Conjugated Polymers Derived from Thiophene-Benzothiadiazole Block and Fluorene/Indenofluorene Units

  • Li, Jianfeng;Tong, Junfeng;Zhang, Peng;Yang, Chunyan;Chen, Dejia;Zhu, Yuancheng;Xia, Yangjun;Fan, Duowang
    • Bulletin of the Korean Chemical Society
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    • v.35 no.2
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    • pp.505-512
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    • 2014
  • A new donor-accepter-donor-accepter-donor (D-A-D-A-D) type 2,1,3-benzothiadiazole-thiophene-based acceptor unit 2,5-di(4-(5-bromo-4-octylthiophen-2-yl)-2,1,3-benzothiadiazol-7-yl)thiophene ($DTBTTBr_2$) was synthesized. Copolymerized with fluorene and indeno[1,2-b]fluorene electron-rich moieties, two alternating narrow band gap (NBG) copolymers PF-DTBTT and PIF-DTBTT were prepared. And two copolymers exhibit broad and strong absorption in the range of 300-700 nm with optical band gap of about 1.75 eV. The highest occupied molecular orbital (HOMO) energy levels vary between -5.43 and -5.52 eV and the lowest unoccupied molecular orbital (LUMO) energy levels range from -3.64 to -3.77 eV. Potential applications of the copolymers as electron donor material and $PC_{71}BM$ ([6,6]-phenyl-$C_{71}$ butyric acid methyl ester) as electron acceptors were investigated for photovoltaic solar cells (PSCs). Photovoltaic performances based on the blend of PF-DTBTT/$PC_{71}BM$ (w:w; 1:2) and PIF-DTBTT/$PC_{71}BM$ (w:w; 1:2) with devices configuration as ITO/PEDOT: PSS/blend/Ca/Al, show an incident photon-to-current conversion efficiency (IPCE) of 2.34% and 2.56% with the open circuit voltage ($V_{oc}$) of 0.87 V and 0.90 V, short circuit current density ($J_{sc}$) of $6.02mA/cm^2$ and $6.12mA/cm^2$ under an AM1.5 simulator ($100mA/cm^2$). The photocurrent responses exhibit the onset wavelength extending up to 720 nm. These results indicate that the resulted narrow band gap copolymers are viable electron donor materials for polymer solar cells.

Evaluation of MODIS-derived Evapotranspiration According to the Water Budget Analysis (물 수지 분석에 의한 MODIS 위성 기반의 증발산량 평가)

  • Lee, Yeongil;Lee, Junghun;Choi, Minha;Jung, Sungwon
    • Journal of Korea Water Resources Association
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    • v.48 no.10
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    • pp.831-843
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    • 2015
  • This study estimates MODIS-derived evapotranspiration data quality by revised RS-PM algorithm in Seolmacheon test basin. We used latent flux with eddy covariance method to evaluate MODIS-derived spatial evapotranspiration and gap-filled these data by three methods (FAO-PM, MDV and Kalman Filter) and to quantify daily evapotranspiration. Gap-filled daily evapotranspiration data was used to evaluate evapotranspiration computed by revised RS-PM algorithm derived MODIS satellite images. For the water budget analysis, we used soil moisture content that is quantified to average individual soil moisture rate observed by TDR (Time Domain Reflectometry) sensor at soil depth. The soil moisture variation is calculated in consideration from initial to final soil moisture content. According to the result of this study, evapotranspiration computed by revised RS-PM algorithm is very larger than eddy covariance data gap-filled by three methods. Also, water budget characteristics is not closed. We could analysis that MODIS-derived spatial evapotranspiration does not represent actual evapotranspiration in Seolmacheon.

Fitting accuracy of ceramic veneered Co-Cr crowns produced by different manufacturing processes

  • von Maltzahn, Nadine Freifrau;Bernhard, Florian;Kohorst, Philipp
    • The Journal of Advanced Prosthodontics
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    • v.12 no.2
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    • pp.100-106
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    • 2020
  • PURPOSE. The purpose of this in vitro study was to evaluate the fitting accuracy of single crowns made from a novel presintered Co-Cr alloy prepared with a computer-aided design and computer-aided manufacturing (CAD/CAM) technique, as compared with crowns manufactured by other digital and the conventional casting technique. Additionally, the influence of oxide layer on the fitting accuracy of specimens was tested. MATERIALS AND METHODS. A total of 40 test specimens made from Co-Cr alloy were investigated according to the fitting accuracy using a replica technique. Four different methods processing different materials were used for the manufacture of the crown copings (milling of presintered (Ceramill Sintron-group_cer_sin) or rigid alloy (Tizian NEM-group_ti_nem), selective laser melting (Ceramill NPL-group_cer_npl), and casting (Girobond NB-group_gir_nb)). The specimens were adapted to a resin model and the outer surfaces were airborne-particle abraded with aluminum oxide. After the veneering process, the fitting accuracy (absolute marginal discrepancy and internal gap) was evaluated by the replica technique in 2 steps, before removing the oxide layer from the intaglio surface of the crowns, and after removing the layer with aluminum oxide airborne-particle abrasion. Statistical analysis was performed by multifactorial analysis of variance (ANOVA) (α=.05). RESULTS. Mean absolute marginal discrepancy ranged between 20 ㎛ (group_cer_npl for specimens of Ceramill NPL) and 43 ㎛ (group_cer_sin for crowns of Ceramill Sintron) with the oxide layer and between 19 ㎛ and 28 ㎛ without the oxide layer. The internal gap varied between 33 ㎛ (group_ti_nem for test samples of Tizian NEM) and 75 ㎛ (group_gir_nb for the base material Girobond NB) with the oxide layer and between 30 ㎛ and 76 ㎛ without the oxide layer. The absolute marginal discrepancy and the internal gap were significantly influenced by the fabrication method used (P<.05). CONCLUSION. Different manufacturing techniques had a significant influence on the fitting accuracy of single crowns made from Co-Cr alloys. However, all tested crowns showed a clinically acceptable absolute marginal discrepancy and internal gap with and without oxide layer and could be recommended under clinical considerations. Especially, the new system Ceramill Sintron showed acceptable values of fitting accuracy so it can be suggested in routine clinical work.

Aberrant Expression of Cx Isoforms in the Adult Caput Epididymis exposed to Estradiol Benzoate or Flutamide at the Weaning

  • Lee, Ki-Ho
    • Development and Reproduction
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    • v.21 no.4
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    • pp.379-389
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    • 2017
  • Connexin (Cx) involves in the regulation of various physiological functions of tissue by forming a channel, a gap junction which allows direct cell-cell communication, between adjacent cells. The effect of a single subcutaneous treatment of estradiol benzoate (EB) or flutamide (Flu) at the weaning age on the expression of Cx isoforms in the adult caput epididymis was evaluated in this research. Using quantitative real-time PCR analysis, a low-dose of EB [$0.015{\mu}g/kg$ body weight (BW)] caused significant decreases of Cx30.3, Cx32, Cx40, Cx43, and Cx45 mRNA levels and no change of Cx26, Cx31, Cx31.1, Cx37 transcript levels. The treatment of a high-dose EB ($1.5{\mu}g/kg\;BW$) resulted in reduced expression of Cx30.3, Cx31, Cx43, and Cx45 but increased expression of Cx37 and Cx40. Expression of all Cx isoforms examined, except Cx31, was significantly increased by the treatment of a low-dose Flu ($500{\mu}g/kg\;BW$). However, the treatment of a high-dose Flu (5 mg/kg BW) led significant expressional suppression of Cx30.3, Cx31, Cx31.1, Cx32, Cx40, Cx43, and Cx45 but an increase of Cx37 transcript level. With the comparison of previous findings, the expression of Cx isoforms in the adult epididymis after the exposure to EB or Flu is likely differentially regulated in regional-specific and/or exposed postnatal age-specific manner.