• 제목/요약/키워드: GAP43

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Congressional Control of Bureaucracy in the United States: Ex Ante vs. Ex Post Control Mechanisms

  • Park, Hong Min
    • 미국학
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    • 제43권1호
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    • pp.115-143
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    • 2020
  • The U.S. Congress has been known to effectively control the bureaucracy. On one hand, Congress adjusts the degree of discretion provided to the bureaucracy when making agencies or legislation: ex ante control. On the other hand, it also performs the oversight activities to punish or correct undesirable behaviors of bureaucrats: ex post control. While the dynamics of each control mechanism is widely examined theoretically, few have attempted to empirically investigate this with a special attention to partisan politics in Congress. I attempt to fill this gap by measuring the two types of control mechanisms, testing theoretical assertions, and analyzing the dynamics under the two control mechanisms.

단일 복구조정활동 하에 단계적 퇴화를 가지는 단일기계 생산일정계획 (Single Machine Scheduling Problem with Step-deterioration under A Rate-modifying Activity)

  • 김병수
    • 산업경영시스템학회지
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    • 제37권3호
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    • pp.43-50
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    • 2014
  • In this paper, we deal with a single machine scheduling problems integrating with step deterioration effect and a rate-modifying activity (RMA). The scheduling problem assumes that the machine may have a single RMA and each job has the processing time of a job with deterioration is a step function of the gap between recent RMA and starting time of the job and a deteriorating date that is individual to all jobs. Based on the two scheduling phenomena, we simultaneously determine the schedule of step deteriorating jobs and the position of the RMA to minimize the makespan. To solve the problem, we propose a hybrid typed genetic algorithm compared with conventional GAs.

How Consumers Differently Perceive about Green Market Environments: Across Different Consumer Groups in Green Attitude-behaviour Dimension

  • Kim, So-Yun;Rha, Jong-Youn
    • International Journal of Human Ecology
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    • 제15권2호
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    • pp.43-57
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    • 2014
  • Consumers differ with respect to the level of green attitudes and green purchase behavious and different consumer would have different perceptions on green market environment. This study attempted to explain how consumers perceive green market environment differently across different consumer groups in attitude-behaviour dimension in green consumption. After identifying the four consumer groups based on their attitude toward green purchase and green purchase behaviours, a multinomial logistic analysis and a stepwise discriminant analysis were conducted. This study found that reliability in green market was the most critical factor that contributes to enlarge positive green consumers. Also, the role of reference persons and adequate price of green products were also found to be important to stimulate green buying. By understanding the different role of those factors in each group of consumers, this study provided group-specific implications to expand green consumers.

A GENERALIZATION OF A RESULT OF CHOA ON ANALYTIC FUNCTIONS WITH HADAMARD GAPS

  • Stevic Stevo
    • 대한수학회지
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    • 제43권3호
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    • pp.579-591
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    • 2006
  • In this paper we obtain a sufficient and necessary condition for an analytic function f on the unit ball B with Hadamard gaps, that is, for $f(z)\;=\;{\sum}^{\infty}_{k=1}\;P_{nk}(z)$ (the homogeneous polynomial expansion of f) satisfying $n_{k+1}/n_{k}{\ge}{\lambda}>1$ for all $k\;{\in}\;N$, to belong to the weighted Bergman space $$A^p_{\alpha}(B)\;=\;\{f{\mid}{\int}_{B}{\mid}f(z){\mid}^{p}(1-{\mid}z{\mid}^2)^{\alpha}dV(z) < {\infty},\;f{\in}H(B)\}$$. We find a growth estimate for the integral mean $$\({\int}_{{\partial}B}{\mid}f(r{\zeta}){\mid}^pd{\sigma}({\zeta})\)^{1/p}$$, and an estimate for the point evaluations in this class of functions. Similar results on the mixed norm space $H_{p,q,{\alpha}$(B) and weighted Bergman space on polydisc $A^p_{^{\to}_{\alpha}}(U^n)$ are also given.

Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction

  • Eltobshy, Somaia A.G.;Hussein, Abdelaziz M.;Elmileegy, Asaad A.;Askar, Mona H.;Khater, Yomna;Metias, Emile F.;Helal, Ghada M.
    • The Korean Journal of Physiology and Pharmacology
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    • 제23권3호
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    • pp.203-217
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    • 2019
  • The present study was designed to examine the effect of heme oxygenase-1 (HO-1) induction by cobalt protoporphyrin (CoPP) on the cardiac functions and morphology, electrocardiogram (ECG) changes, myocardial antioxidants (superoxide dismutase [SOD] and glutathione [GSH]), and expression of heat shock protein (Hsp) 70 and connexin 43 (Cx-43) in myocardial muscles in isoproterenol (ISO) induced myocardial infarction (MI). Thirty two adult male Sprague Dawely rats were divided into 4 groups (each 8 rats): normal control (NC) group, ISO group: received ISO at dose of 150 mg/kg body weight intraperitoneally (i.p.) for 2 successive days; ISO + Trizma group: received (ISO) and Trizma (solvent of CoPP) at dose of 5 mg/kg i.p. injection 2 days before injection of ISO, with ISO at day 0 and at day 2 after ISO injections; and ISO + CoPP group: received ISO and CoPP at a dose of 5 mg/kg dissolved in Trizma i.p. injection as Trizma. We found that, administration of ISO caused significant increase in heart rate, corrected QT interval, ST segment, cardiac enzymes (lactate dehydrogenase, creatine kinase-muscle/brain), cardiac HO-1, Hsp70 with significant attenuation in myocardial GSH, SOD, and Cx-43. On the other hand, administration of CoPP caused significant improvement in ECG parameters, cardiac enzymes, cardiac morphology; antioxidants induced by ISO with significant increase in HO-1, Cx-43, and Hsp70 expression in myocardium. In conclusions, we concluded that induction of HO-1 by CoPP ameliorates ISO-induced myocardial injury, which might be due to up-regulation of Hsp70 and gap junction protein (Cx-43).

NGS 기술 활용 돌연변이체 해석 및 연구현황 (Current status and prospects to identify mutations responsible for mutant phenotypes by using NGS technology)

  • 정유진;류호진;조용구;강권규
    • Journal of Plant Biotechnology
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    • 제43권4호
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    • pp.411-416
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    • 2016
  • NGS 기술은 전체 게놈 시퀀싱 및 reference 게놈에 alignment에 의해 돌연변이 표현형에 관련된 돌연변이 식별에 이용한다. 그러나 품종 및 계통들을 resequence 하였을 경우 기존의 reference 게놈에 구조적 변이가 보이며, reference와 맞지 않는 게놈지역에서 돌연변이들은 단순한 alignment로 찾을 수 없다. 본 리뷰에서는 NGS 기술을 이용하여 돌연변이체로부터 변이 관련 유전자를 식별하는 MutMap, MutMap-Gap 및 MutMap+ 방법을 기술하였고 지금까지의 연구현황에 대해 기술하였다. 아울러 이들 방법은 nucleotide-binding site-leucine rich repeat (NBS-LRR) 그룹들의 병 저항성 유전자와 같이 구조적 변이를 가진 유전자를 분리하는 등 유용성에 대해 고찰하였다.

새터민 청소년의 수학학습 실태 및 적응 요인 분석 (An Analysis on the State of Adjustment on Mathematical Education for Adolescent North Korean Defectors)

  • 연보라;김홍찬
    • 한국학교수학회논문집
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    • 제15권3호
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    • pp.467-486
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    • 2012
  • 본 연구는 새터민 청소년들의 수학학습 적응 실태를 파악하고 수학학습 적응에 영향을 미치는 요인들을 분석함으로써 수학학습 적응력 신장을 위한 개선방향을 찾으려는 데 그 목적이 있다. 이를 위해 새터민 대안학교에 재학 중인 새터민 학생 43명을 대상으로 12개월 동안의 참여관찰과 수학학습 적응에 관한 설문조사를 실시하였다. 새터민 청소년들은 탈북 과정 중에서 제대로 제도화된 교육과정을 받지 못함에 따라 기초 수리능력의 부족과 낮은 학력수준으로 인한 인지적 요인뿐 아니라 수학교과에 대한 자아개념, 수학교과에 대한 학습 습관, 수학불안, 수학교과 인식 등의 정의적 영역, 그리고 수업 변인 등 환경적 영역의 요인들이 수학학습 적응에 있어서 다각적으로 영향을 미침을 알 수 있었다.

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태양동기궤도 위성군 궤도 최적화에 관한 연구 (Optimization of Sun-synchronous Spacecraft Constellation Orbits)

  • 김화영;노태수;정옥철;정대원;최진행
    • 한국항공우주학회지
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    • 제43권2호
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    • pp.141-148
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    • 2015
  • 본 논문에서는 각각 독립적으로 설계된 태양동기궤도 위성에 위성군 개념을 적용하여 다중 위성의 효율적인 운영에 대한 방법론을 제시한다. 이를 위해 태양동기궤도 설계 관점을 단순히 지방시나 태양동기성을 유지하는 것에 국한하지 않고, 지상국과 영상목표물의 교신 및 관측시간등을 고려하여 위성운영의 효율성을 높이고자 한다. 위성의 효율적인 운영을 위해 위성과 단일 목표물을 고려한 새로운 운영요소(Operation Parameter)를 정의하고, 이를 이용하여 위성의 운영효율성을 판단할 수 있는 운영효율성 지표(Figure of Merit)를 정의한다. 상용 소프트웨어인 MATLAB과 STK의 연동을 통해 비선형 시뮬레이션 기반의 수치최적화 기법을 적용하여 사용자의 요구사항을 만족하는 임무궤도를 재설계함으로써 본 연구의 적용가능성을 확인하였다.

Growth Promoting Effects of Oriental Medicinal Drugs on Sciatic Nerve Regeneration in the Rat

  • Jo Hyun-Kyung;NamGung Uk;Seol In-Chan;Kim Yoon-Sik
    • 동의생리병리학회지
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    • 제19권6호
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    • pp.1666-1672
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    • 2005
  • Oriental medicinal drugs have a broad spectrum of clinical use for the cure of nervous system diseases including brain ischemic damages or neuropathies. Yet, specific drugs or drug components used in the oriental medicine in relation to none fiber regeneration are not known. In the present study, possible growth promoting effects of oriental medicinal drugs were investigated in the injured sciatic nerve system in the rat. By immunofluorescence staining, we found that Jahageo (JHG, Hominis placenta) increased Induction levels of axonal growth associated protein GAP-43 in the rat sciatic none. Small growth promoting activity was found in Golsebo (GSB, Drynariae rhizoma) and Baikhasuo (BHSO, Polygoni multiflori radix) drugs. JHG also increased cell cycle protein Cdc2 levels in the injured area of the sciatic nerves. Immunofluorescence staining indicated that induced Cdc2 protein was mostly localized in the Schwann cells in the injury area, implying that JHG activity might be related to increased Schwann cell proliferation during axonal regeneration. Moreover, levels of phospho-extracellular signal-regulated (ERK) pathway in the injured neNes were elevated by JHG treatment while levels of total ERK were unaltered. In vivo measurement of axonal regeneration using retrograde tracer showed that JHG, GSB and BHSO significantly enhanced Dil-labeled regenerating motor neurons compared with saline control. The present data suggest that oriental medicinal drugs such as JHG, GSB, and BHSO may be a useful target for developing specific drugs of axonal regeneration.

IDENTIFICATION OF TWO-DIMENSIONAL VOID PROFILE IN A LARGE SLAB GEOMETRY USING AN IMPEDANCE MEASUREMENT METHOD

  • Euh, D.J.;Kim, S.;Kim, B.D.;Park, W.M.;Kim, K.D.;Bae, J.H.;Lee, J.Y.;Yun, B.J.
    • Nuclear Engineering and Technology
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    • 제45권5호
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    • pp.613-624
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    • 2013
  • Multi-dimensional two-phase phenomena occur in many industrial applications, particularly in a nuclear reactor during steady operation or a transient period. Appropriate modeling of complicated behavior induced by a multi-dimensional flow is important for the reactor safety analysis results. SPACE, a safety analysis code for thermal hydraulic systems which is currently being developed, was designed to have the capacity of multi-dimensional two-phase thermo-dynamic phenomena induced in the various phases of a nuclear system. To validate the performance of SPACE, a two-dimensional two-phase flow test was performed with slab geometry of the test section having a scale of $1.43m{\times}1.43m{\times}0.11m$. The test section has three inlet and three outlet nozzles on the bottom and top gap walls, respectively, and two outlet nozzles installed directly on the surface of the slab. Various kinds of two-dimensional air/water flows were simulated by selecting combinations of the inlet and outlet nozzles. In this study, two-dimensional two-phase void fraction profiles were quantified by measuring the local gap impedance at 225 points. The flow conditions cover various flow regimes by controlling the flow rate at the inlet boundary. For each selected inlet and outlet nozzle combination, the water flow rate ranged from 2 to 20 kg/s, and the air flow rate ranged from 2.0 to 20 g/s, which corresponds to 0.4 to 4 m/s and 0.2 to 2.3 m/s of the superficial liquid and gas velocities based on the inlet port area, respectively.