• Weed & Turfgrass Science
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• 제2권4호
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• pp.387-394
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• 2013

Rhizoctonia spp. 에 의한 Rhizoctonia 마름병은 잔디에서 중요한 병이며, 골프장에서 잔디의 좋은 품질을 유지하기 위하여 살균제를 사용하고 있다. 본시험은 포장에서 분리한 R. solani AG-1 IB, R. cerealis 및 R. solani AG2-2에 대한 침투성 살균제인 flutolanil, pyraclostrobine, and hexaconazole에 대하여 실내에서 상대적인 균사생장을 효과적으로 50%억제하는 $EC_{50}$농도를 결정하는 시험을 수행하였다. 각각 살균제에 대한 감수성은 3종의 Rhizoctonia균주에 대하여 5 수준의 농도를 사용하였다. 3종류의 살균제에 대한 $EC_{50}$ 값은 R. solani AG-1 IB에서 가장 낮았다. 하지만, R. solani AG2-2에 대한 살균제 감수성은 pyraclostrobine 과 flutolanil에서 평균 $EC_{50}$ 값이 0.026 ${\mu}g\;a.i.\;ml^{-1}$ 와 0.044 ${\mu}g\;a.i.\;ml^{-1}$ 로 가장 높았다. R. cerealis은 hexaconazole에서 $EC_{50}$ 값이 0.022 ${\mu}g\;a.i.\;ml^{-1}$로 가장 감수성이 낮았다. 각각의 살균제의 $EC_{50}$값을 사용하여 두 농약을 혼용한 3종의 조합에서 3종의 병원균에 대한 균사 생장억제율은 R. solani AG2-2에서 가장 높았다. 본 연구결과는 포장에서 Rhizoctonia 마름병을 방제하기 위하여 실내에서 침투성 살균제에 대한 반응을 확인할 수 있었다.

• 대한수의학회지
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• 제17권1호
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• pp.13-16
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• 1977

In order to know the current status of sensitivity of Corynebacterium renale to some antimicrobial agents of current use, the sensitivity of 37 strains isolated from urine and vaginal cavity of healthy Korean native cattle and dairy cattle was studied by agar plate dilution method, and their sensitivity according to serological types was compared. The antimicrobial agents tested were streptomycin (SM), erythromycin (EM), oxytetracycline (OT), penicillin G (PC), gentamycin (GM), kanamycin (KM), ampicillin (AP), leucomycin (LM), chloramphenicol (CM), colistin (CL), sulfadimethoxine (SDM) and sulfadiazine (SDZ). Most strains were highly sensitive to PC, GM, AP, LM and KM, and moderate to CM and OT, but resistant to SM, EM, CL, SDM and SDZ. Serological type II was more sensitive to EM, SDM and SDZ than type I and II, but more resistant to SM.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1996년도 추계학술대회 논문집
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• pp.417-420
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• 1996

We have investigated air/200ppm NO$_2$ gas-detector characteristics of using CuTBP (Copper-tetra-tert-butylphthalocyanine) chemiresistor devices. The CuTBP films were made by Langmuir-Blodgett (LB) techniques. Sensitivity, response time, recovery time, and repoducibility of the devices were measured by current-voltage characteristics. To increase sensitivity, interdigital electrode was used. It was found that a conductance G increases monotonically as the number of interdigital electrode increases, and a Sensitivity, Reproducibility is stable. As far as a current is concerned, the current when N=25 is greater than that when N=1 by 70 or so. It indicates that the number of interdigital electrodes affects the current, sensitivity and stability We have also investigated applicability of the CuTBP chemiresistor device for a gas detector.

• 약학회지
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• 제33권6호
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• pp.372-376
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• 1989

Equilibrium swelling and pH-sensitivity of a polyelectrolyte copolymer hydrogel were controlled by employing copolymers with different hydrophilic-hydrophobic balances. Model pH-sensitive hydrogels, e.g., poly(methacrylic acid), poly(methacrylic acid-co-acrylamide), poly(methacrylic acid-co-2-hydroxyethylmethacrylate), poly(methacrylic acid-co-styrene) were synthesized at various monomer compositions. As hydrophobicity of the copolymer hydrogels increased, the equilibrium swelling decreased while the pH-sensitivity increased. In the case of poly(methacrylic acid-co-acrylamide), polymer-polymer interaction significantly affected the equilibrium swelling and provided a wide range control of pH-sensitivity.

• The Plant Pathology Journal
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• 제33권6호
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• pp.589-596
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• 2017

Chemical management of dollar spot in turf may lead to the development of Sclerotinia homoeocarpa populations with reduced fungicide sensitivity. The objective of this study was to investigate resistance of S. homoeocarpa isolates to triazole fungicides and to test cross-resistance among three triazole fungicides. A total of 66 isolates of S. homoeocarpa were collected from 15 golf courses across Korea, and tested via in vitro sensitivity assay against hexaconazole, propiconazole and tebuconazole. $EC_{50}$ values of the isolates to these fungicides were distributed in the range of $0.001-1.1\;a.\;i.\;{\mu}g\;ml^{-1}$. Based on the $EC_{50}$ values, twelve representative strains were selected as sensitive isolates including control and insensitive isolates with respect to each fungicide. At a concentration of $0.1\;a.\;i.\;{\mu}g\;ml^{-1}$ for all fungicides, the selected strains were distinguished as sensitive or resistant isolates with the mycelial growth inhibition rate of 50% as the criterion. The $EC_{50}$ values of resistant strains exposed to hexaconazole, propiconazole and tebuconazole were 20-50 times, 50-70 times, and 77 times greater, respectively, than that of the control strains. Two isolates of S. homoeocarpa S0-41 and Sh14-2-1 showed sensitivity toward all the fungicides used, while two other isolates Sh7-5-1 and Sh2-1-1 showed resistance to all fungicides. Each isolate showed similar resistance to the three types of triazole fungicides, whereby cross-resistance of isolates was confirmed in the present study; all three triazole fungicide combinations displayed significant correlation coefficients equivalent to or greater than 0.8.

• 전자공학회논문지D
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• 제36D권7호
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• pp.26-33
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• 1999

4빔 브릿지형 압저항형 실리콘 가속도 센서에서 빔의 위치가 가속도 센서의 특성에 어떤 영향을 주는지 조사하기 위해서 빔의 위치가 서로 다른 3가지 형태의 가속도 센서를 FEM(finite element method)을 사용하여 해석하고, SDB(silicon direct bonding) 웨이퍼를 사용하여 RIE(reactive ion etching)와 KOH(potassium hydroxide) 애칭 공정으로 제조하였다. 세가지 형태의 가속도 센서에 대한 FEM 해석 경과, 첫 번째 공진 주파수와 Z축 감도는 세구조 모두 같게 나타났으나, 두 번째와 세 번째의 공진 주파수 및 X, Y축의 감도는 다른 것으로 나타났다. 제조된 가속도 센서의 특성을 살펴볼 때, 세 가지 형태의 센서는 비록 첫 번째 공진 주파수와 Z축 감도가 정확하게 일치하지는 않았지만, 첫 번째 공진 주파수는 1.3 ~ 1.7 KHz, Z축 감도는 5 V 인가시 180 ~ 220 lN/G, 타축감도는 1.7 ~ 2 %를 가지는 것으론 나타났다.

• 한국농공학회논문집
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• 제63권6호
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• pp.141-150
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• 2021

In order to assess the impact of climate change on irrigation reservoirs, climate exposure (EI), sensitivity (SI), and potential impact (PI) were evaluated for 1,651 reservoirs nationwide. Climate exposure and sensitivity by each reservoir were calculated using data collected from 2011 to 2020 for seven proxy variables (e.g. annual rainfall) and six proxy variables (e.g. irrigation days), respectively. The potential impact was calculated as the weighted sum of climate exposure and sensitivity, and was classified into four levels: 'Low (PI<0.4)', 'Medium (PI<0.6)', 'High (PI<0.8)', and 'Critical (PI≥0.8)'. The result showed that both the climate exposure index and the sensitivity index were on average high in Daegu and Gyeongbuk with high temperature and low rainfall. About 79.8% of irrigation reservoirs in Daegu, Gyeongbuk, and Ulsan with high climate exposure and sensitivity resulted in a 'High' level of potential impact. On the contrary, 64.5% of the study reservoirs in Gyeongnam and Gangwon showed 'Low' in potential impact. In further studies, it is required to reorganize the proxy variables and the weights in accordance with practical alternatives for improving adaptive capacity to drought, and it is expected to contribute to establishing a framework for vulnerability assessment of an irrigation reservoir.

• 농약과학회지
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• 제13권3호
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• pp.171-176
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• 2009

2008년 5~6월 사이 상주 지역 감 과수원으로부터 분리한 탄저병균(Colletotrichum gloeosporioides)의 prochloraz manganese complex, tebuconazole, mancozeb+myclobutanil, fluquinconazole+prochloraz, tebuconazole+toIyfluanid 등 총 5종의 살균제에 대한 반응을 조사하였다. 분리한 탄저병균 110균주 중 prochloraz ($250\;{\mu}g/m{\ell}$)과 tebuconazole($125{\mu}g/m{\ell}$)에 대하여 각각 97.3%와 98.2%의 균주가 91%이상의 균사생육이 억제되는 것으로 나타났다. Mancozeb + myclobutanil, fluquinconazole + prochloraz 및 tebuconazole + tolyfluanid 스테롤 생합성 저해제와 다른 약제의 합제에 대하여 91% 이상의 균사생육이 억제되는 균주의 비율은 각각 96.4, 99.1 및 96.4%로 나타났다. 공시한 약제 중 감수성이 가장 높은 약제는 fluquinconazole + prochloraz로 나타났다. Tebuconazole과 tebuconazole + tolyfluanid 약제간 r=0.85으로 약제간 교차 저항성의 위험성이 높은 것으로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.173-177
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• 2013

Backgrounds: Tanshinone IIA (TIIA), a phenanthrenequinone derivative extracted from Salvia miltiorrhiza BUNGE, has been reported to be a natural anti-cancer agent in a variety of tumor cells. However, the effect of TIIA on gastric cancer cells remains unknown. In the present study, we investigated the influence of TIIA on the malignant phenotype of SGC7901 gastric cancer cells. Methods: Cells cultured in vitro were treated with TIIA (0, 1, 5, $10{\mu}g/ml$) and after incubation for different periods, cell proliferation was measured by MTT method and cell apoptosis and cell cycling were assessed by flow cytometry (FCM). The sensitivity of SGC7901 gastric cancer cells to anticancer chemotherapy was investigated with the MTT method, while cell migration and invasion were examined by wound-healing and transwell assays, respectively. Results: TIIA (1, 5, $10{\mu}g/ml$) exerted powerful inhibitory effects on cell proliferation (P < 0.05, and P < 0.01), and this effect was time- and dose-dependent. FCM results showed that TIIA induced apoptosis of SGC7901 cells, reduced the number of cells in S phase and increased those in G0/G1 phase. TIIA also significantly increased the sensitivity of SGC7901 gastric cancer cells to ADR and Fu. Moreover, wound-healing and transwell assays showed that TIIA markedly decreased migratory and invasive abilities of SGC7901 cells. Conclusions: TIIA can reverse the malignant phenotype of SGC7901 gastric cancer cells, indicating that it may be a promising therapeutic agent.

• 한국컴퓨터정보학회논문지
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• 제15권4호
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• pp.11-18
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• 2010

Fuzzy c-means(FCM)는 퍼지 집합을 응용한 간단하지만 효율적인 클러스터링 방법 중 하나이다. FCM은 여러 응용 분야에서 성공적으로 활용되어 왔지만, 초기화와 잡음에 민감하고 볼록한 형태의 클러스터들만 다룰 수 있는 문제점이 있다. 이 논문에서는 이러한 FCM의 문제점을 해결하기 위해 전역 클러스터링(global clustering) 기법과 커널 클러스터링(kernel clustering) 기법을 결합하여 새로운 비선형 클러스터링 기법인 커널 전역 FCM(kernel global fuzzy c-means, KG-FCM)을 제안한다. 전역 클러스터링은 클러스터링의 초기화를 위한 방법 중 하나로, 순차적으로 클러스터를 하나씩 추가함으로써 초기화에 민감한 FCM의 한계를 극복할 수 있도록 해준다. FCM의 잡음 민감성과 볼록한 클러스터들만 다룰 수 있는 한계를 극복하기 위한 방법은 여러 가지가 있으며 커널 클러스터링이 그 중 하나이다. 커널 클러스터링은 사용하는 커널을 바꿈으로써 쉽게 확장이 가능하므로 이 논문에서는 커널 클러스터링을 사용하였다. 두 방법을 결합함으로써 제안한 방법은 위에서 언급한 문제점들을 해결할 수 있으며, 이는 가상 및 실제 데이터를 이용한 실험 결과를 통해 확인할 수 있다.