• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.4
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• pp.271-276
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• 2018

The purpose of pilot clinical trial is to evaluate the efficacy and safety of acupuncture therapy on TEWL(Transepidermal Water Loss) and skin hydration. A total of 36 human who visited Dongshin University Oriental Medical Center from October 2nd, 2015 to July 31st, 2016 were included in the pilot clinical trial. Acupuncture therapy was performed at Gokji(LI11) and Daechu(GV14). We observed change of TEWL(Transepidermal Water Loss), skin hydration before and after acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically significant decline($8.01{\pm}2.55{\rightarrow}6.58{\pm}1.97g/h/m2$, $7.40{\pm}2.65{\rightarrow}4.99{\pm}1.89g/h/m2$). Index of skin hydration showed statistical significance($52.83{\pm}6.53{\rightarrow}56.82{\pm}7.24$, $63.50{\pm}8.57{\rightarrow}64.96{\pm}8.48$). To evaluate the safety, vital sign check were conducted and showed no statistically significant result. And there were no severe adverse events during this study. According to the above pilot clinical trial, it is suggested acupuncture therapy were effective for skin moisturizing.

• Preventive Nutrition and Food Science
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• v.17 no.1
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• pp.87-91
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• 2012

Three oat cultivars and one oat breeding line were evaluated for chemical, hydration and pasting properties. Protein, starch and ${\beta}$-glucan levels ranged 11.13~14.37, 56.37~64.86 and 3.44~4.76%, respectively. The oat cultivars Daeyang and Seonyang contained higher ${\beta}$-glucan levels of 4.76 and 4.35%. The Daeyang variety had a higher water absorption index (WAI) of 2.83~3.35 (g/g), but a lower water solubility index (WSI) of 8.67~11.08%. Daeyang and Seonyang cultivars showed higher peak and trough viscosity, but lower breakdown and setback, indicating that they easily swell, and thus could possibly provide the desirable viscosity of an oat product. The ${\beta}$-glucan levels were correlated positively with WAI, peak and trough viscosity, and negatively to WSI, breakdown and setback viscosity.

• Korean Journal of Pharmacognosy
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• v.30 no.2
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• pp.151-157
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• 1999

In order to find less toxic antiherpetic agents, the effect of natural quercetin on the plaque formation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction assay. Quercetin caused a concentration-dependent reduction in the plaque formation of herpesviruses. It also exhibited more potent antiherpetic activity on HSV-1 with effective concentration $(EC_{50})$ of $18.7\;{\mu}g/ml$ than on HSV-2 with $EC_{50}$ of $24.5\;{\mu}g/ml$. The combined antiherpetic effects of quercetin with nucleoside antiherpetic agents, acyclovir and vidarabine, were examined on the multiplication of these two strains of herpesviruses in Vero cells by the combination assay. The results of combination assay were evaluated by the combination index (CI) that was calculated by the multiple drug effect analysis. The combinations of quercetin with acyclovir on HSV-1 and HSV-2 showed more potent synergism with CI values of $0.19{\sim}0.89$ for 50%, 70%, 90% effective levels than those with vidarabine with CI values of $0.43{\sim}1.46$.

• The Plant Pathology Journal
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• v.25 no.4
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• pp.422-428
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• 2009

Studies were conducted to identify the sources of resistance in mungbean recombinant inbred lines (RILs) in Thailand against mungbean yellow mosaic disease (MYMD). 146 mungbean RILs in $F_8$ series were evaluated in a field including resistant parent NM-10-12-1 and susceptible parent KPS 2 during summer 2008 under high inoculum pressure. The RILs were subsequently scored for disease symptom severity ratings (DSSR) using a new scale. Observations regarding DSSR and % disease index (%DI) showed that the tested RILs responded differently to the disease. A large number of RILs (132) were found highly susceptible, 12 were susceptible, 3 were tolerant and one was resistant. Overall screening results showed that three RILs, viz. line no. 30, 100 and 101 had minimum DSSR and % disease index thus they are good source of resistance to MYMD in spite of high disease pressure and can therefore be used directly as varieties to manage the disease in Thailand.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.3
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• pp.321-325
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• 2002

Karyotype analysis was carried out on blood samples of 30 water buffaloes belonging to different breed groups (i.e. Philippine Carabao (PC), Indian Murrah (IM), Bulgarian Murrah (BM), "$F_1$ 50% IM-50% PC", "$F_1$ 50% BM-50% PC" and "75% IM-25% PC"), using the modified Leucocyte Culture Technique. The modal chromosome numbers of the PC, "$F_1$ 50% IM-50% PC", "$F_1$ 50% BM-50% PC", IM, BM and "75% IM-25% PC" were 2n=48, 49, 49, 50, 50 and 50, respectively. The water buffalo chromosomes are mostly acrocentric (79.67%) and the remainder submetacentric (20.33%). Results of the ordinary least square analysis showed significant breed effects (p<0.01) on other karyotypic characteristics (i.e. relative length, arm ratio and centromeric index). Significant correlation between karyotypic characteristics and some animal performance traits were also found. The significant correlation values imply that karyotypic characteristics can be used as important criteria to select potentially productive young water buffaloes. In the future, more production and reproduction traits from non-institutional herds should be included in the analysis to reveal meaningful correlations with various karyotypic characteristics.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.6
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• pp.533-542
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• 2014

In this study TBM disc cutter prediction models including Gehring, CSM and NTNU models were investigated and the characteristics of the models were examined. The influence of penetration, uniaxial compressive strength and abrasiveness index on the models was analyzed. The life of disc cutter linearly increases with penetration per revolution and decreases with increasing uniaxial compressive strength of rocks. As the abrasiveness index, CAI, increases, the life of disc cutter in Gehring and CSM model decreases. On the contrary, the life of disc cutter life in NTNU model decreases with increasing CLI. Also, comparisons of predicted disc life were made between models using actual job site data.

• Geomechanics and Engineering
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• v.22 no.1
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• pp.35-48
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• 2020

This paper provides methods for the deterministic and reliability-based design of the support pressures necessary to prevent tunnel face collapse. The deterministic method is developed by extending the use of the unique load multiplier, which is embedded within OptumG2/G3 with the intention of determining the maximum load that can be supported by a system. Both two-dimensional and three-dimensional examples are presented to illustrate the applications. The obtained solutions are validated according to those derived from the existing methods. The reliability-based method is developed by incorporating the Response Surface Method and the advanced first-order second-moment reliability method into the bisection algorithm, which continuously updates the support pressure within previously determined brackets until the difference between the computed reliability index and the user-defined value is less than a specified tolerance. Two-dimensional reliability-based support pressure is compared and validated via Monte Carlo simulations, whereas the three-dimensional solution is compared with the relationship between the support pressure and the resulting reliability index provided in the existing literature. Finally, a parametric study is carried out to investigate the influences of factors on the required support pressure.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.6
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• pp.944-947
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• 2007

This study was conducted to study the effects of dietary garlic powder on laying performance, egg traits and blood serum cholesterol level of quails. A total of three hundred quails (Coturnix coturnix japonica) aged nine weeks were used. They were allocated to 3 dietary treatments. Each treatment comprised 5 replicates of 20 quails. The diets were supplemented with 0, 5 and 10 g/kg garlic powder. The experimental period lasted 21 weeks. The addition of garlic powder did not significantly affect body weight, egg production, feed consumption, feed efficiency, egg shell thickness, egg albumen index, egg yolk index and egg Haugh unit. Adding 5 and 10 g/kg garlic powder to the laying quail diets increased egg weight (p<0.01). Egg yolk cholesterol and blood serum cholesterol concentration were reduced with garlic powder supplementation. The results of this study demonstrated that garlic powder addition had a significant cholesterol-reducing effect in serum and egg yolk without adverse effects on performance and egg traits of laying quails.

• Journal of Korean Society on Water Environment
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• v.25 no.1
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• pp.37-47
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• 2009

This study analyzes the effect of alternatives and estimates alternatives evaluation index (AEI) using PCSWMM and weighted summation method. PCSWMM considering combined sewer overflows (CSOs) in the Mokgamcheon watershed was used and effectiveness analysis of alternative was conducted to develop not only flowrate but also the pollutant of BOD and SS. Indicators of AEI are selected using sustainability evaluation concept, driver-pressure-state-impact-response (DPSIR) framework and calculated by weighted summation method. After estimating AEI, alternatives was classified into three groups G (Good), A (Acceptable) and P (Poor) grade. As a results, it is analyzed that alternatives applied to Oryucheon were G grade and those of Yeokgokcheon were P grade and the remainings were 'A' grade. This result will be effective to the integrated watershed management for sustainablility.

• Journal of Korean Biological Nursing Science
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• v.17 no.4
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• pp.363-371
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• 2015

Purpose: The purpose of this study was to assess alcohol and caffeine intake and identify the impact of alcohol and caffeine intake on body mass index, alcohol use disorder, and quality of sleep among university students. Methods: This study design was accomplished with a cross sectional survey and conducted from May to June 2014. One hundred and twenty-four freshmen of E university in S city, Korea were selected and evaluated by self-administered questionnaires. Alcohol and caffeine intake were measured by self-reported recall. The data were analyzed using descriptive analysis, independent t-test, one-way ANOVA, Pearson's correlation, and multiple linear regression. Results: The average amount of alcohol intake was $175.02{\pm}219.97g$ and the proportion of freshmen who took in more than 40 g per day of alcohol was 75%. The average amount of caffeine intake was $116.79{\pm}111.14mg$. Factors influencing alcohol use disorder were dwelling type (t=2.25, p=.027) and alcohol intake (t=8.11, p<.001). And, the factor influencing quality of sleep was caffeine intake (t=3.88, p<.001). Conclusion: In order to reduce the harmful drinking of university students, preventive activities for freshmen are required and efforts on the part of the school needed.