• 동의생리병리학회지
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• 제32권4호
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• pp.271-276
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• 2018

The purpose of pilot clinical trial is to evaluate the efficacy and safety of acupuncture therapy on TEWL(Transepidermal Water Loss) and skin hydration. A total of 36 human who visited Dongshin University Oriental Medical Center from October 2nd, 2015 to July 31st, 2016 were included in the pilot clinical trial. Acupuncture therapy was performed at Gokji(LI11) and Daechu(GV14). We observed change of TEWL(Transepidermal Water Loss), skin hydration before and after acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically significant decline($8.01{\pm}2.55{\rightarrow}6.58{\pm}1.97g/h/m2$, $7.40{\pm}2.65{\rightarrow}4.99{\pm}1.89g/h/m2$). Index of skin hydration showed statistical significance($52.83{\pm}6.53{\rightarrow}56.82{\pm}7.24$, $63.50{\pm}8.57{\rightarrow}64.96{\pm}8.48$). To evaluate the safety, vital sign check were conducted and showed no statistically significant result. And there were no severe adverse events during this study. According to the above pilot clinical trial, it is suggested acupuncture therapy were effective for skin moisturizing.

• Preventive Nutrition and Food Science
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• 제17권1호
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• pp.87-91
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• 2012

Three oat cultivars and one oat breeding line were evaluated for chemical, hydration and pasting properties. Protein, starch and ${\beta}$-glucan levels ranged 11.13~14.37, 56.37~64.86 and 3.44~4.76%, respectively. The oat cultivars Daeyang and Seonyang contained higher ${\beta}$-glucan levels of 4.76 and 4.35%. The Daeyang variety had a higher water absorption index (WAI) of 2.83~3.35 (g/g), but a lower water solubility index (WSI) of 8.67~11.08%. Daeyang and Seonyang cultivars showed higher peak and trough viscosity, but lower breakdown and setback, indicating that they easily swell, and thus could possibly provide the desirable viscosity of an oat product. The ${\beta}$-glucan levels were correlated positively with WAI, peak and trough viscosity, and negatively to WSI, breakdown and setback viscosity.

• 생약학회지
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• 제30권2호
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• pp.151-157
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• 1999

In order to find less toxic antiherpetic agents, the effect of natural quercetin on the plaque formation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction assay. Quercetin caused a concentration-dependent reduction in the plaque formation of herpesviruses. It also exhibited more potent antiherpetic activity on HSV-1 with effective concentration $(EC_{50})$ of $18.7\;{\mu}g/ml$ than on HSV-2 with $EC_{50}$ of $24.5\;{\mu}g/ml$. The combined antiherpetic effects of quercetin with nucleoside antiherpetic agents, acyclovir and vidarabine, were examined on the multiplication of these two strains of herpesviruses in Vero cells by the combination assay. The results of combination assay were evaluated by the combination index (CI) that was calculated by the multiple drug effect analysis. The combinations of quercetin with acyclovir on HSV-1 and HSV-2 showed more potent synergism with CI values of $0.19{\sim}0.89$ for 50%, 70%, 90% effective levels than those with vidarabine with CI values of $0.43{\sim}1.46$.

• The Plant Pathology Journal
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• 제25권4호
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• pp.422-428
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• 2009

Studies were conducted to identify the sources of resistance in mungbean recombinant inbred lines (RILs) in Thailand against mungbean yellow mosaic disease (MYMD). 146 mungbean RILs in $F_8$ series were evaluated in a field including resistant parent NM-10-12-1 and susceptible parent KPS 2 during summer 2008 under high inoculum pressure. The RILs were subsequently scored for disease symptom severity ratings (DSSR) using a new scale. Observations regarding DSSR and % disease index (%DI) showed that the tested RILs responded differently to the disease. A large number of RILs (132) were found highly susceptible, 12 were susceptible, 3 were tolerant and one was resistant. Overall screening results showed that three RILs, viz. line no. 30, 100 and 101 had minimum DSSR and % disease index thus they are good source of resistance to MYMD in spite of high disease pressure and can therefore be used directly as varieties to manage the disease in Thailand.

• Asian-Australasian Journal of Animal Sciences
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• 제15권3호
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• pp.321-325
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• 2002

Karyotype analysis was carried out on blood samples of 30 water buffaloes belonging to different breed groups (i.e. Philippine Carabao (PC), Indian Murrah (IM), Bulgarian Murrah (BM), "$F_1$ 50% IM-50% PC", "$F_1$ 50% BM-50% PC" and "75% IM-25% PC"), using the modified Leucocyte Culture Technique. The modal chromosome numbers of the PC, "$F_1$ 50% IM-50% PC", "$F_1$ 50% BM-50% PC", IM, BM and "75% IM-25% PC" were 2n=48, 49, 49, 50, 50 and 50, respectively. The water buffalo chromosomes are mostly acrocentric (79.67%) and the remainder submetacentric (20.33%). Results of the ordinary least square analysis showed significant breed effects (p<0.01) on other karyotypic characteristics (i.e. relative length, arm ratio and centromeric index). Significant correlation between karyotypic characteristics and some animal performance traits were also found. The significant correlation values imply that karyotypic characteristics can be used as important criteria to select potentially productive young water buffaloes. In the future, more production and reproduction traits from non-institutional herds should be included in the analysis to reveal meaningful correlations with various karyotypic characteristics.

• 한국터널지하공간학회 논문집
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• 제16권6호
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• pp.533-542
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• 2014

본 연구에서는 Gehring, CSM, NTNU 모델을 이용한 디스크 커터 수명 예측 방법과 각 모델이 가지는 특징을 살펴보았다. 디스크 커터 수명에 크게 영향을 주는 요소인 관입깊이, 암석의 일축압축강도, 마모지수의 변화가 각각의 예측 모델들에 미치는 영향을 분석하였다. 디스크 커터 수명은 1회전당 관입깊이에 선형적으로 증가하였고, 일축압축강도의 증가에 따라 감소하는 경향을 보였다. 마모지수인 CAI 값이 증가함에 따라 Gehring과 CSM 모델에서의 디스크 커터 수명은 감소하였으나, CLI 값이 증가할수록 NTNU 모델의 디스크 커터 수명은 증가하는 경향을 보였다. 그리고 실제 현장 자료를 이용하여 디스크 커터 수명을 상호 비교하였다.

• Geomechanics and Engineering
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• 제22권1호
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• pp.35-48
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• 2020

This paper provides methods for the deterministic and reliability-based design of the support pressures necessary to prevent tunnel face collapse. The deterministic method is developed by extending the use of the unique load multiplier, which is embedded within OptumG2/G3 with the intention of determining the maximum load that can be supported by a system. Both two-dimensional and three-dimensional examples are presented to illustrate the applications. The obtained solutions are validated according to those derived from the existing methods. The reliability-based method is developed by incorporating the Response Surface Method and the advanced first-order second-moment reliability method into the bisection algorithm, which continuously updates the support pressure within previously determined brackets until the difference between the computed reliability index and the user-defined value is less than a specified tolerance. Two-dimensional reliability-based support pressure is compared and validated via Monte Carlo simulations, whereas the three-dimensional solution is compared with the relationship between the support pressure and the resulting reliability index provided in the existing literature. Finally, a parametric study is carried out to investigate the influences of factors on the required support pressure.

• Asian-Australasian Journal of Animal Sciences
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• 제20권6호
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• pp.944-947
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• 2007

This study was conducted to study the effects of dietary garlic powder on laying performance, egg traits and blood serum cholesterol level of quails. A total of three hundred quails (Coturnix coturnix japonica) aged nine weeks were used. They were allocated to 3 dietary treatments. Each treatment comprised 5 replicates of 20 quails. The diets were supplemented with 0, 5 and 10 g/kg garlic powder. The experimental period lasted 21 weeks. The addition of garlic powder did not significantly affect body weight, egg production, feed consumption, feed efficiency, egg shell thickness, egg albumen index, egg yolk index and egg Haugh unit. Adding 5 and 10 g/kg garlic powder to the laying quail diets increased egg weight (p<0.01). Egg yolk cholesterol and blood serum cholesterol concentration were reduced with garlic powder supplementation. The results of this study demonstrated that garlic powder addition had a significant cholesterol-reducing effect in serum and egg yolk without adverse effects on performance and egg traits of laying quails.

• 한국물환경학회지
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• 제25권1호
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• pp.37-47
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• 2009

This study analyzes the effect of alternatives and estimates alternatives evaluation index (AEI) using PCSWMM and weighted summation method. PCSWMM considering combined sewer overflows (CSOs) in the Mokgamcheon watershed was used and effectiveness analysis of alternative was conducted to develop not only flowrate but also the pollutant of BOD and SS. Indicators of AEI are selected using sustainability evaluation concept, driver-pressure-state-impact-response (DPSIR) framework and calculated by weighted summation method. After estimating AEI, alternatives was classified into three groups G (Good), A (Acceptable) and P (Poor) grade. As a results, it is analyzed that alternatives applied to Oryucheon were G grade and those of Yeokgokcheon were P grade and the remainings were 'A' grade. This result will be effective to the integrated watershed management for sustainablility.

• Journal of Korean Biological Nursing Science
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• 제17권4호
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• pp.363-371
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• 2015

Purpose: The purpose of this study was to assess alcohol and caffeine intake and identify the impact of alcohol and caffeine intake on body mass index, alcohol use disorder, and quality of sleep among university students. Methods: This study design was accomplished with a cross sectional survey and conducted from May to June 2014. One hundred and twenty-four freshmen of E university in S city, Korea were selected and evaluated by self-administered questionnaires. Alcohol and caffeine intake were measured by self-reported recall. The data were analyzed using descriptive analysis, independent t-test, one-way ANOVA, Pearson's correlation, and multiple linear regression. Results: The average amount of alcohol intake was $175.02{\pm}219.97g$ and the proportion of freshmen who took in more than 40 g per day of alcohol was 75%. The average amount of caffeine intake was $116.79{\pm}111.14mg$. Factors influencing alcohol use disorder were dwelling type (t=2.25, p=.027) and alcohol intake (t=8.11, p<.001). And, the factor influencing quality of sleep was caffeine intake (t=3.88, p<.001). Conclusion: In order to reduce the harmful drinking of university students, preventive activities for freshmen are required and efforts on the part of the school needed.