• Journal of the Speleological Society of Korea
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• no.90
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• pp.35-56
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• 2009

The purpose of this paper is to analyze the implementation of the karst infrastructure systems for the u-cave. IT based u-cave represents spatial information derived fields, such as geographical distribution of the cave boundaries, physical configuration of the cave locations and formation characteristics of the karst history. These three aspects relate to karst infrastructure systems, cave monitoring center and spatial database implementation. In terms of the IT based u-cave infrastructure implementation systems, the u-cave depends on IT contents and spatial features. uIT contents are strongly related to IT839 strategy due to the national agenda is "u-Korea". Cave should contribute to u-cave construction through the spatial analyses methods including USN, RFID, LiDAR, ELD, and GIS technologies. For these methods various cave functions will guide to u-cave's distribution, location, and characteristics of karst. The infrastructure consists of landforms and speleothem facilities, underground related facilities, environmental protection systems, and cave planning. These six units of the cave infrastructures have spatial databases that consist of spatial configuration, such as 4-D in order to draw the spatial distribution of the limestone and lava caves. IT based u-cave system infrastructure implementation should deal with IT convergence to generate fusion affects.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.45-53
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• 2014

In this study, we analyzed the next generation ITS (C-ITS) technology trends, focusing on the national and international C-ITS projects. Based on the promotion practices of developed countries, we pointed out the lack of linkages with the existing ITS infrastructure. As a way to overcome this problem, we proposed the three-direction to enable the existing ITS infrastructure corresponding to the C-ITS. First one is developing a technique to improve the performance of the existing ITS infrastructure and automate the performance management (Performance-enhanced ITS). Second, developing active sensors or fusion sensor which along with V2X communication technology implement of an active safety driving support system (Safety-enhanced ITS). Third, we need to develop a technology that generate the new advanced traffic data by integrating the collected data from existing ITS infrastructure and nomadic device (Cloud-ITS). By improving the function of the existing ITS infrastructure for adaptation to the new V2X communication environment, we enhanced the efficiency of maintenance performance and would maximize the benefit of the introduction of C-ITS.

• Journal of Microbiology and Biotechnology
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• v.27 no.2
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• pp.335-341
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• 2017

The complexity of the bacterial recombination system is a barrier for the construction of bacterial mutants for the further functional investigation of specific genes. Several protocols have been developed to inactivate genes from the genus Pseudomonas. Those protocols are complicated and time-consuming and mostly do not enable easy construction of multiple knock-ins/outs. The current study describes a single and double crossover-recombination system using an optimized vector-free allele-exchange protocol for gene disruption and gene replacement in a single species of the family Pseudomonadaceae. The protocol is based on self-ligation (circularization) for the DNA cassette which has been obtained by overlapping polymerase chain reaction (Fusion-PCR), and carries an antibiotic resistance cassette flanked by homologous internal regions of the target locus. To establish the reproducibility of the approach, three different chromosomal genes (ncRNA31, rpoN, rpoS) were knocked-out from the root-associative bacterium Pseudomonas stutzeri A1501. The results showed that the P. stutzeri A1501 mutants, which are free of any plasmid backbone, could be obtained via a single or double crossover recombination. In order to optimize this protocol, three key factors that were found to have great effect on the efficiency of the homologous recombination were further investigated. Moreover, the modified protocol does not require further cloning steps, and it enables the construction of multiple gene knock-in/out mutants sequentially. This work provides a simple and rapid mutagenesis strategy for genome editing in P. stutzeri, which may also be applicable for other gram-negative bacteria.

• KIPS Transactions on Computer and Communication Systems
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• v.2 no.8
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• pp.357-368
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• 2013

Our society has evolved into a fully connected society in a mixed reality environment enabling various knowledge sharing / management / control / creation due to the expansion of broadband ICT infrastructure, smart devices, cloud services and social media services. Therefore cyber threats have increased with the convenience. The society of the future can cause more complex and subtle problems, if you do not have an effective response to cyber threats, due to fusion of logical space and physical space, organic connection of the smart object and the universalization of fully connected society. In this paper, we propose the strategy to build knowledge-base as the basis to actively respond to new cyber threats caused by future various environmental changes and the universalization of fully connected society.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.121-128
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• 2019

Fashion display is a part of fashion brand marketing strategy. Today, due to the improvement of consumers' aesthetics, consumers' requirements for display and decoration in fashion stores are also increasing. And color design plays an important psychological role in the display. In this study, the color design of the display is taken as the center, and the status quo, emotional characteristics, psychological and physiological functions of the color design of the display are taken care of. After analyzing specific examples through previous studies, the methods and rules of color design are explored on the basis of these studies, and the principles of color matching beauty are studied to prompt the color design that follows in the display. First, there should be some emphasis on the overall color allocation. Second, the structure of the store needs to be considered. Third, we need to emphasize scientific and reasonable color matching sequence. To sum up, judging this research is of positive significance to the later research on color design.

• Journal of the Korea Society of Computer and Information
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• v.23 no.11
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• pp.159-165
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• 2018

In this study, it is analyzed that keywords of the interest in the 4th industrial revolution for science and Technician K women's university students, areas to prioritize in the strategy of 4th industry revolution, to research compare analyze the recognition of science technology such as the most necessary education, human resource development of universities and companies in Korea and abroad according to the technology trend required in the 4th Industrial revolution era and which area to prepare for the 4th industrial revolution. The survey result shows different thoughts of science and Technician(KOFST) and the women university students. In the 1) 4th industrial revolution, the 96% of former are interested, while 60% of latter are interested. And in the most used keywords, the former group used AI(24%), Fusion new industry(21%) the most, while the latter group used AI(34%), Robot(18%). And, 3) in the strategic priority, the science technology experts are interested in education, R&D system innovation(27%), IoT, Information and Communication(26%) and the university students are interested in IoT, Information and Communication(31%), AI(28%). Finally, 4) the science technology experts thought of Autonomous Vehicle(20%), 3D Printer(7%), AI(16%) important, while the women university students thought of AI(27%), VR/Augmented Reality(17%), and Autonomous Vehicle(16%) the most necessary education. In the 4th industrial revolution, we need people with ability to solve complicated problems with creativity based on understanding and absorbing new knowledge and thinking of converged idea.

• The Journal of the Convergence on Culture Technology
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• v.5 no.1
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• pp.1-12
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• 2019

Even though Korea has lost its important modern era due to Japanese colonialism, it is in the rank of advanced nation today. It is common to think that there was no creative and innovative design activity because it was highly constrained by design activities. Is there no creative idea or innovative design in this period of design activity? As a result of analyzing the various products of modern design left in the question, I was able to find a new and unique Innovation in 10 fields. In other words, today, we can confirm that we have utilized innovative strategies in the field of design such as brand family, new sign system, modernism style, localization, star marketing, one source multi use, private brand, nature friendly, fusion and parody strategy.

• Journal of Digital Convergence
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• v.17 no.11
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• pp.105-115
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• 2019

This study was intended to analyze the effect of emotional marketing on brand awareness and purchase intention in the coffee shop and investigates how SNS usage play moderating effect roles between motional marketing and purchase intention. The results of analysis are summarized as follows. First, emotional marketing has a positive effect on purchase intention(especially, taste factor and visual facto). Second, in the analysis of the effect of emotional marketing on brand awareness, the significant influence factors were the taste factor, tactile factor, visual factor and auditory factor. Third, as a result of analyzing the effect of brand awareness on purchase intention, it was found that brand awareness had a significant positive(+) effect on purchase intention. Fourth, it was analyzed that the moderating effect of SNS usage between emotional marketing and purchasing intention is to be positive(+) influence in the all detail factors. Therefore, In the start-up stages, it may be helpful to actively use emotional marketing and SNS usage for business activation.

• Biomolecules & Therapeutics
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• v.29 no.1
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• pp.73-82
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• 2021

Hsp90 is often overexpressed with activated form in cancer cells, and many key cellular proteins are dependent upon the Hsp90 machinery (these proteins are called "client protein"). Nowadays, more client proteins and more inhibitors of Hsp90 are being discovered. Chaetocin has been identified as an inhibitor of histone methyl transferase SUV39H1. Herein, we find that Chaetocin is an inhibitor of Hsp90 which binds to the C-terminal of Hsp90α. Chaetocin inhibited a variety of Hsp90 client proteins including AMl1-ETO and BCL-ABL, the mutant fusion-protein in the K562 and HL-60 cells. SUV39H1 mediates epigenetic events in the pathophysiology of hematopoietic disorders. We found that inhibition of Hsp90 by Chaetocin and 17-AAG had ability to induce degradation of SUV39H1 through proteasome pathway. In addition, SUV39H1 interacted with Hsp90 through co-chaperone HOP. These results suggest that SUV39H1 belongs to a client protein of Hsp90. Moreover, Chaetocin was able to induce cell differentiation in the two cells in the concentration range of Hsp90 inhibition. Altogether, our results demonstrate that SUV39H1 is a new client protein of Hsp90 degradated by Chaetocin as a novel C-terminal inhibitor of Hsp90. The study establishes a new relationship of Chaetocin and SUV39H1, and paves an avenue for exploring a new strategy to target SUV39H1 by inhibition of Hsp90 in leukemia.

• Journal of Information Technology Applications and Management
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• v.28 no.3
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• pp.49-58
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• 2021

Due to the increasing interest in wellness aroused by the aging population and the pursuing feature of active old age, Korean elderly set importance on long life with their healthy condition. Following the change in the paradigm of the medical delivery system from hospital-oriented, treatment-oriented to personal-centered and self-care, Service design application of Smart Healthcare for the elderly became valuable. Smart Healthcare is a healthcare service provided through the fusion of ICT technologies including mobile/wearable devices, IoT, big data, and information technology, and it is utilized to prevent diseases managing abundant health information and living habits. As a methodology for delivering such Smart Healthcare to the elderly, Service design can be adopted. Therefore, this study would like to present the perquisites of Smart Healthcare design for the elderly through analyzing the results from in-depth interview methods between the elderly and medical staff. As a result of this study, guidelines for Service design application of health vulnerability management for the elderly utilizing smart phones were presented. Therefore, this study presented four prerequisites composed of 'high level of supplementation and ethical decision making', 'improvement of inequality in accessibility and experience', 'resolving problems in policy implementation' and 'user-friendliness' for the Smart Healthcare service design for the elderly. Overall, Service design is expected to play an innovative role in improving the quality of life for the elderly through the process of collecting and delivering information on Smart Healthcare centered on the experience of the elderly.