• 제목/요약/키워드: Fusion Age

검색결과 280건 처리시간 0.023초

Neural Tube Defects with Abdominal Wall Defects in Sibling Dogs (복벽결손을 동반한 동복자견의 신경관결손)

  • Cho, Sung-Jin;Kim, Ok-Jin
    • Journal of Veterinary Clinics
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    • 제26권5호
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    • pp.467-471
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    • 2009
  • This report describes Neural Tube Defects (NTDs) with Abdominal Wall Defects (AWDs) on the sibling of Yorkshire terriers. The NTDs and AWDs are rare serious congenital defects. The NTDs are neurulation abnormality that results from to failed transformation of the neurual tube by the incomplete closure of the embryonic neural plate. These dysraphic states range form mild to severe according to developmental malformation that include fusion defects of skull (crania bifida; CB) and fusion defects of vertebrae (spina bifida; SB). The AWDs are genetic defects that results from to failed formation of abdominal wall and cavity. These dysraphic states are omphalocele and gastroschisis. The 12-month dam was delivered by caesarian section and 4 littermate had obvious malformations. One male dead stillbirth fetus (L1) was revealed the extruded abdominal viscera, omphalocele. One female fetus (L2) was died within 1 hour after birth with defects of abdominal muscle upper umbilicus, gastroschisis. 3rd fetus (L3) was died within 36 hours after parturition and revealed a copious dermal and vertebral defects on the midline thorax, upper SB asperta. 4th fetus (L4) is still growing well now at 6 months but at the 2 week age, appears hairy nevus on the frontal cranium and dorsal thoracic portion. The radiograph of L1 and L2 are shown decrease bony density of calvarium and L3 was shown defect of spinose processes of the T9-T13. On our knowledge, this is first report of the SB and CB in Yorkshire terrier. And also sibling of NTDs with AWDs that has not previously been reported in the dog.

Transmission of Bovine $\beta-Casein/Human$ Lactoferrin Fusion Gene in Transgenic Cattle

  • Han Yong-Mahn;Koo Deog-Bon;Park Jung-Sun;Kim Young-Hun;Lee Kea-Joung;Lee Kyung-Kwang
    • Reproductive and Developmental Biology
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    • 제29권4호
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    • pp.235-239
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    • 2005
  • This study was conducted to test whether the transgenic cattle pass the transgene to their progeny through germ cells, and whether the transgene is expressed in the mammary gland of ransgenic cows. Two male ransgenic calves were born from IVF-derived embryos injected with bovine $\beta-casein/human$ lactoferrin fusion gene and then grew up to be reproducible. Semen was collected from a transgenic bull after 18 mon of age and then frozen. Bovine oocytes matured in vitro were fertilized with spermatozoa of the transgenic bull and cultured in $50\;{\mu}L$ drops of CRlaa medium supplemented with 3 mg/mL BSA. After 48 h of culture, cleaved embryos were determined for the presence of transgenes by DNA polymerase chain reaction (PCR). Proportion of transgene positives among bovine embryos fertilized with sperm of the transgenic bull was $20.9\%$ (28/134). One of transgenic bulls did not produce transgenic sperm. Out of 34 calves produced from recipient heifers inseminated with semen of the other bull, 3 $(8.8\%)$ were transgenic animals (2 females and 1 male). Thus, one transgenic bull showed a low transmission frequency below Mendelian levels in both the IVF-derived embryos and his progeny. It was demonstrated by Southern blot that copy numbers of the transgene in the transgenic progeny enhanced about 1.8 times as compared to those of the founder bull The results demonstrate that the transgenic bull carrying human lactoferrin gene could pass his transgene to the progeny through germ cells, although he is a germ-line mosaic.

The Effects of family of Origin Experiences and Self-Differentiation on Marital Relationship and Parent-Child Relationship in the Nuclear Family among Married Men and Women (기혼남녀의 원가족 경험과 자기분화가 핵가족의 부부관계와 부모자녀관계에 미치는 영향)

  • Cho, So-Hee;Chung, Hye-Jeong
    • Korean Journal of Human Ecology
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    • 제17권5호
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    • pp.873-889
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    • 2008
  • The purpose of this study was to investigate the effects of family-of-origin experiences(parents' marital adjustment and affectionate relationship with parents) and self-differentiation on the nuclear family relationships(marital adjustment of married men women, and affectionate relationship with child). Data were collected using self-administered questionnaire method with 159 married men and 193 married women. The results showed that first, married men and women perceived the level of family-of-origin experiences lower than that of nuclear family relationships, and there were significant differences in the level of marital adjustment across sex, age, marital status, and income. Second, there was significant positive correlation between family-of-origin experiences and self-differentiation, between family-of-origin experiences and the nuclear family relationships, and between self-differentiation and the nuclear family relationships. Third, multiple regression analyses indicated that parents' marital adjustment and emotional cutoff were the powerful predictors of marital adjustment of married men women. Finally, women's affectionate relationship with child was predicted by such variables as affectionate relationship with parents, fusion with others, and emotional fusion, whereas men's affectionate relationship with child was predicted by such variables as affectionate relationship with parents, emotional reactivity, and I-position.

Early Weight Bearing Ambulation after Arthroscopic Ankle Arthrodesis (관절경적 족관절 유합술 후 조기 체중부하 보행)

  • Kim, Yoon-Chung;Cho, Sung-Wook;Chung, Jin-Wha
    • Journal of Korean Foot and Ankle Society
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    • 제18권4호
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    • pp.183-188
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    • 2014
  • Purpose: The accepted general management principle after ankle arthrodesis is to maintain non-weight bearing for 6 to 8 weeks. The aim of this study was to report clinical outcome of patients allowed early weight bearing after arthroscopic arthrodesis. Materials and Methods: We analyzed medical records and radiographs to determine fusion rate and complication risk of 22 sequential patients allowed to walk under short leg cast within 3 days after arthroscopic ankle arthrodesis using 2 screws from January 2008 to June 2012. The minimum follow-up period was 18 months, and the mean age of the patients was 67 years. Results: The mean visual analog scale was decreased from 8.9 points preoperatively to 2.3 points after 12 months. Complete ankle fusion was achieved in 19 patients (86.4%) at 3-month follow-up. There were 2 cases of delayed union and one case of nonunion at 12-month follow-up. There was no other complication such as wound problem, persistent swelling of the ankle. Conclusion: Bony union may not be interfered even though patients were allowed to walk under cast within a few days after arthroscopic ankle arthrodesis.

Position Information Acquisition Method Based on LED Lights and Smart Device Camera Using 3-Axis Moving Distance Measurement (3축 이동량 측정을 이용한 LED조명과 스마트단말 카메라기반 위치정보 획득 기법)

  • Jung, Soon-Ho;Lee, Min-Woo;Kim, Ki-Yun;Cha, Jae-Sang
    • The Journal of Korean Institute of Communications and Information Sciences
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    • 제40권1호
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    • pp.226-232
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    • 2015
  • As the age of smart device has come, recently many application services related to smart phone are developing. The LBS(Location Based Service) technique is considered as one of the most important techniques to support location based application services. Usually the smart phone acquires the information of position by using the position recognition systems and sensors such as GPS(Global Positioning System) and G-Sensor. However, since the GPS signal from the satellite can hardly be received in the indoor environments, new LBS techniques for the indoor environment are required. In this paper, to solve the problem a position information transceiver using LED lights and smart phone camera sensor is proposed. We proved the possibility of the proposed positioning system through the experiments in the laboratory for the practical verification.

Analysis of Performance of Creative Education based on Twitter Big Data Analysis (트위터 빅데이터 분석을 통한 창의적 교육의 성과요인 분석)

  • Joo, Kilhong
    • Journal of Creative Information Culture
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    • 제5권3호
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    • pp.215-223
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    • 2019
  • The wave of the information age gradually accelerates, and fusion analysis solutions that can utilize these knowledge data according to accumulation of various forms of big data such as large capacity texts, sounds, movies and the like are increasing, Reduction in the cost of storing data accordingly, development of social network service (SNS), etc. resulted in quantitative qualitative expansion of data. Such a situation makes possible utilization of data which was not trying to be existing, and the potential value and influence of the data are increasing. Research is being actively made to present future-oriented education systems by applying these fusion analysis systems to the improvement of the educational system. In this research, we conducted a big data analysis on Twitter, analyzed the natural language of the data and frequency analysis of the word, quantitative measure of how domestic windows education problems and outcomes were done in it as a solution.

Development and Application of Teaching Materials for Geological Fieldwork in the Area of Bongwhabong, Buan-gun, Jeonbuk, Korea (전북 부안군 봉화봉 일대의 야외지질 학습자료 개발 및 적용)

  • Park, Jae-Moon;Ryang, Woo-Hun;Cho, Kyu-Seong;Kim, Seung-Bum
    • Journal of the Korean earth science society
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    • 제30권7호
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    • pp.883-896
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    • 2009
  • This study is to develop teaching materials for geological fieldwork around Bonghwabong area in the national park of the Byeonsan Peninsula, Buangun, Jeonbuk. The developed materials are applied in the geological fieldwork of science high school students to maximize the effects of use. The sedimentary succession of the Bonghwabong area in the Cretaceous age, Mesozoic, represents large-scale and distinctive sedimentary structures on the sea cliffs, which are utilized as teaching materials for earth science fieldwork. The area of Bonghwabong also comprises various geological structures related to advanced learning programs as well as those within the curriculum of high school earth science. A five-step fieldwork model was applied to 15 students in clubs related to earth science in a science high school. This study used a qualitative methodology to analyze students' responses that were gathered about the process of fieldwork. During the activity, a qualitative analysis was carried out by using discussions and interviews both with the students and the teacher. Results indicated that the fieldwork activity using teaching materials was effective in helping the students improve their self-directed learning and practical understanding of earth science.

Study on TV Home Shopping in the Age of broadcast-Communication Fusion (방통융합시대에 TV 홈쇼핑 정책에 관한 연구)

  • Kim, Man-Hwan
    • Journal of Distribution Research
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    • 제16권5호
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    • pp.19-41
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    • 2011
  • Home shopping is called the flower of future distribution. Among them, for TV home shopping, Korea should lead the industry as an advanced country in IT technology. It is difficult for small and medium businesses, however. This is due to the failure of the policies of Korea Communications Commission. In order to complement such policy failure, this study intends to analyze the preceding domestic studies and foreign status, and reflect such on the policy. Especially the domestic business will be predicted through foreign home shopping status and policy cases, and the items that should be supplemented with governmental policy in order to vitalize small & medium businesses were analyzed; these should be actively reflected by the government. In case of general PP, it already runs on the registration system, and the home shopping channel should also be the same and be committed to the market. The increased number of channels would allow a greater opportunity for small and medium businesses who are the suppliers, and for the consumers, the product prices would be able to be stabilized at an appropriate cost and high quality and diversity of items could be obtained through home shopping, thus improving consumer welfare. If it is difficult to adopt the registration system for home shopping right away, the best alternative is to strengthen the approval system. As home shopping requires a re-approval every 3 years, strengthened re-approval conditions would resolve part of the problem.

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Clinical Evaluation of Surgical Treatments for Ten Cases of Tuberculous Spondylitis (결핵성 척추염 10례의 수술적 치료에 관한 임상적 고찰)

  • Whee, Sung Mock;Eoh, Whan;Nam, Do Hyun;Lee, Jung Il;Kim, Jong Soo;Hong, Seung-Chyul;Shin, Hyung Jin;Park, Kwan;Kim, Jong-Hyun
    • Journal of Korean Neurosurgical Society
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    • 제30권11호
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    • pp.1314-1319
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    • 2001
  • Objects : Because of the nonspecific nature of symptoms in tuberculous spondylitis, a delay in the diagnosis can result in progressive neurologic deficits. The authors evaluate the clinical and the radiological results of the 10 cases of surgically treated tuberculous spondylitis. Clinical materials & Methods : We retrospectively analyzed the medical records of 10 patients with tuberculous spondylitis who were treated between February 1996 and March 2000. Six patients were female, and four were male. Mean age was 43 years old, and mean follow-up period was 20.5 months. All patients were treated with 12 months of antituberculous medication postoperatively, and were followed by complete blood count, ESR, spine X-ray and MRI. Results : The lumbar spine was involved in 5 patients, the thoracic in 4, and the thoracolumbar in one. The infected vertebral bodies were 2.8 in average. The associated lesions were pulmonary tuberculosis in 3 cases, and renal tuberculosis in one. Five patients were treated by anterior debridement and fusion with bone graft using anterior instrumentation, 2 with anterior debridement and fusion with bone graft(Hong Kong procedure only), 1 with Hong Kong procedure with posterior spinal instrumentation, and 2 were managed with posterior debridement and posterior spinal instrumentation. All patients improved after operation, and the average kyphotic angle decreased postoperatively. Postoperatively, one patient had a fistula at the operative site. Conclusion : The debridement and minimal level fusion of motion segment with instrument fixation is one of surgical option for tuberculous spondyltis to preserve the spine motion segment as much as possible. Spine instability and kyphosis were prevented by anterior and posterior spinal instrumentation. But, large number of cases and longer period follow-up study in future will be needed to confirm the long term results.

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Development and Application of Teaching Materials for Geological Fieldwork in Jeokbyeokgang Area, Gyeokpo, Byeonsan, Korea (변산반도 격포 적벽강 일대 야외지질 학습자료 개발 및 적용)

  • Cho, Kyu-Seong;Ryang, Woo-Hun;Shin, Sun-Seon;Oh, Jae-Myeong;Chung, Duk-Ho
    • Journal of the Korean earth science society
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    • 제33권7호
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    • pp.658-671
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    • 2012
  • This study is to develop teaching materials for the geological fieldwork of Jeokbyeokgang area located in the national park of the Byeonsan-bando National Park, Buangun, Jeonbuk, Korea. The developed teaching materials are used in middle school science to effectively teach the fieldwork of the area. The sedimentary succession of Jeokbyeokgang area in the Cretaceous age, Mesozoic, represents the large-scale and distinctive sedimentary structures on sea cliffs, which are worth developing as teaching materials for the earth science fieldwork. The area of Jeokbyeokgang also comprises various geological structures related to the advanced learning programs as well as those within the curriculum of earth science in middle school level. A five-step fieldwork model was applied to 20 students in middle school earth science. This study quantitatively analyzed students' responses to the process of the fieldwork activity. Results indicated that the fieldwork activity using the developed teaching materials was effective in helping the students to improve their self-directed learning and practical understanding of earth science.