• 한국식품위생안전성학회지
• /
• 제35권3호
• /
• pp.252-260
• /
• 2020

본 연구는 특수용도식품에 함유되어 있는 비타민B₁₂와 비오틴에 대하여 식품의 복잡한 매질 특성에 특이성을 확보할 수 있도록 현행 식품공전 시험법을 개선하고자 하였다. 식품공전에서 비타민B₁₂와 비오틴의 시험법에 항체반응을 통해서 분석물질과 특이적으로 결합하여 그 외의 성분들을 효과적으로 제거할 수 있는 면역친화성 컬럼을 도입하여 시험용액을 정제 및 농축함으로써 전처리 과정을 개선하였다. 식품 등 시험법 마련 표준절차에 관한 가이드라인에 따라 밸리데이션(특이성, 직선성, 검출한계, 정량한계, 정확도, 정밀도)을 수행하고 개선된 시험법을 이용하여 유통 중인 특수용도식품의 대상 품목에 대해 시험법 적용여부를 확인하였다. 본 연구사업의 수행으로 시험·검사의 정확성을 증대시켜 특수용도식품 품질관리에 대한 신뢰성을 더 높일 것으로 본다.

• 한국식품위생안전성학회지
• /
• 제39권2호
• /
• pp.72-82
• /
• 2024

본 연구는 자일로올리고당의 과학적이고 체계적인 표준화된 시험법을 마련하여 다양한 제형의 제품에 적용하고자 하였다. 최적화된 시험법을 마련하기 위해 초음파 처리 시간, 산 가수분해 시간 및 농도를 검토하여 전처리 방법을 비교 평가하였으며, HPLC-UVD를 이용하여 시료 중의 자일로올리고당을 분석하였다. 분석 시 1-phenyl-3-methyl-5-pyrazoline (PMP)으로 유도체화하고, photo diode array (PDA)가 장착된 high performance liquid chromatography (HPLC) (Nanospace SI-2)를 사용하였으며, 칼럼은 Cadenza C₁₈ (4.6 × 250 mm, 3 ㎛)이었으며, 이동상은 pH를 6.0으로 맞춘 20 mM 인산완충용액과 아세토니트릴을 78:22 비율로 혼합하여 사용하였고, 0.5 mL/min 유속으로 254 nm로 하여 분석하였다. 건강기능식품 등 시험법 마련 표준절차에 관한 가이드라인에 따라 밸리데이션을 수행하고, 표준화된 시험법을 이용하여 유통 중인 건강기능식품 대상 품목에 대해 시험법 적용 여부를 확인하였다. 표준화된 시험법은 자일로올리고당을 함유한 건강기능식품 품질관리에 대한 신뢰성을 더 높일 것으로 본다.

• 한국실내디자인학회논문집
• /
• 제23권3호
• /
• pp.56-63
• /
• 2014

Furniture has been developed in pursuit of human convenience and comfort, but nowadays it does not consider human users and gradually loses the essence of furniture. Especially furniture design that disregards the relation with space loses both the meaning and purpose of furniture. In this regards, it is necessary to understand the essence of furniture design and establish a design direction for future progress. Based on the relation between furniture and space, this paper intended to study on John Pawson's works that pursued the essence of design focusing on users, and propose a direction in a sense of real meaning for modern furniture design after exploring the characteristic of the furniture design of John Pawson. The study method of this paper was to investigate the design language of John Pawson and analyze his furniture in the morphological structural, functional, and material aspects. Based on such analysis, this study investigated the characteristics of the furniture design and found out what the core of the design that he pursued was. The scope of the study included the Independent Furniture that was restricted furniture collections of Driade and Spatial Furniture designed and installed at the stage of space construction. The study result showed that the design of John Pawson considered 'the suitability to a specific place' as important factor and furniture was planned at the stage of planning space. Each independent furniture defines all spaces in the morphological, lay-out and functional aspects of furniture and emphasizes their own property. As Spatial Furniture shares the function of spatial composition element, Pawson's furniture can be all called Spatial Furniture.

• 콘크리트학회논문집
• /
• 제24권2호
• /
• pp.165-172
• /
• 2012

우리나라는 급격한 도시화 및 산업화를 통하여 토지의 효율적 활용과 하천의 공학적 이치수의 목적만을 위해 하천을 인공화 시켰으며, 더욱이 90년대 이후에는 교통량의 급격한 증가에 따라 개발이 유리한 하천을 복개하여 도로, 주차장 등으로 활용함으로서 하천생태계 파괴와 단절, 도시미관의 훼손 등 많은 문제점을 발생시켰다. 이 연구에서는 우리나라 지형 및 기후에 적합하며 하천의 생태복원 기능 및 자연형 하천의 조기형성 기능을 가지는 친환경 기능성 콘크리트의 개발을 위하여 친수환경 조성과 생태보존에 적합한 기능성 콘크리트의 물리역학적 성능평가 및 구조적 성능평가와 현장적용 성능으로서 식생능력을 평가하였다. 역학적 성능평가 결과, 보강용 PVA섬유 및 실리카퓸의 혼입률이 증가함에 따라 강도가 증가하였고 최적 혼입률은 PVA 섬유 0.05Vol.%, 실리카퓸 10%정도인 것으로 나타났다. 내동해성 평가에서는 PVA섬유 0.05Vol.% 및 실리카퓸 15%를 동시 혼입시 가장 우수한 성능을 발휘 하였다. 구조성능 평가 결과 휨강도가 Plain에 비하여 PVA섬유 0.05Vol% 혼입시 47.7% 강도향상효과를 나타내었고, 휨인성 역시 현저히 개선되는 것으로 나타났다. 현장 적용성 평가를 위한 식생 모니터링 결과, 잔디류가 빨리 발아되었으나 시간이 경과함에 따라 봄철 발아식물인 개양귀비의 생육이 활발하였다. 식피율 측정 결과 모든 모니터링 지점에서 12주 후부터는 95% 이상의 우수한 식피율을 나타내어 친환경 기능성 콘크리트의 우수한 식생기능을 확인하였다.

• 산업식품공학
• /
• 제14권2호
• /
• pp.183-187
• /
• 2010

본 연구에서는 강원도에 자생하는 오가피(Acanthopanax sessilifloru) 열매(Ogaza)를 80% MeOH 추출하고, 기능성 식품소재로써의 기능성을 규명하였다. 오가자 추출물의 페놀성 화합물은 오가자 1 g 당 56.1${\pm}$5.2 mg의 gallic acid로 나타났다. 오가자 추출물 0.25, 0.5, 1, 2 mg/mL은 각각 vitamin C 34.0, 73.0, 194.3, 339.7 $\mu g$/mL에 해당하는 항산화 효과를 보였다. 오가자 추출물 1 과 2 mg/mL의 농도에서 LPS로 유도한 TNF-$\alpha$와 IL-6의 생성량을 각각 22${\pm}$2, 19${\pm}$6% 그리고 18${\pm}$2, 24${\pm}$3% 억제하였다. 또한, 자외선 조사에 의해 증가한 COX-2 luciferase 활성이 오가자 추출물 (0.25, 0.5, 1, 2 mg/mL)에 의해 각각 80${\pm}$1, 83.${\pm}$7, 96${\pm}$4, 98${\pm}$2% 억제됨을 확인하였다. 본 연구를 통해 잎 이나 뿌리에 비해 연구 및 활용도가 낮았던 오가피 열매의 항산화활성 및 항염증 효능을 규명함으로써, 오가자가 고부가가치 기능성 식품소재로 활용 될 수 있는 가능성을 제시하였다.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
• /
• pp.707-710
• /
• 2011

System safety is defined as the state where the hazard risks due to internal system, interface, operation and maintenance are controlled as acceptable levels. It is represented and evaluated either with the risk level of each risk factor with the consideration of operation environments or with Safety Integrity Level (SIL) which is the system functional safety without considering application environments. The assessment results are issued in forms of certificates and they are reused in many cases. However, the conditions and restrictions for different application environments vary in each case, therefore, additional evaluation on the preconditions of assessment in comparison with the actual application environment must be carried out. For the area of train control, TR 50506-1 has been established based on the IEC 62425 (international standard for safety of train control system by RSSB) and EN 50129 (Europe standard) for the further assessment. In this paper, the analysis on TR 5056-1 has been conducted in depth. The purpose of the study is to determine the requirements for inter-acceptability including scope, procedures, principles, examination and suitability. The results can be utilized for the system safety maintenance when new devices or components are introduced in conventional systems.

• 한국의류산업학회지
• /
• 제17권4호
• /
• pp.597-603
• /
• 2015

This study investigates the actual domestic and overseas cyclewear wearing conditions for male high school cyclists. The study results provide factors and degree of dissatisfaction as basic data for cyclewear development. This study was conducted on 35 male high school cyclists (freshman to seniors) by a questionnaire and interview method. Study results were: Male high school cyclists considered functionality as most important when they bought cyclewear and the brand they most often bought was a cheap domestic brand. Dissatisfaction with the crotch, thigh circumference and minimum leg circumference was higher than other parts during wearing. A cyclist is more sensitive to wear because they require more lower body motion than other parts. Cyclewear should be: less transformed even by frequent laundering, made of breathable material and use a sewing technique that minimizes air resistance and increases fit the body. Functional pads ergonomically designed with high tactile materials should be developed to prevent 'saddle sore' and groin soreness region that happens because of a lower body bending posture when cycling. A follow-up study is recommended to further develop excellence in cyclewear functionality and dimension suitability for male high school cyclists through the size system.

• Journal of Applied Biological Chemistry
• /
• 제51권1호
• /
• pp.7-12
• /
• 2008

The suitability of CPWs, by-products of the juice industry, was investigated as a source for the production of cosmeceuticals. Four kinds of CPWs, CW, CWE, CWER, and CWEA, were examined for their antioxidant potentials in terms of DPPH radical-scavenging ability for anti-wrinkle applications, inhibition of tyrosinase or melanin production for whitening products, and anti-inflammatory effects to treat various skin diseases such as atopic dermatitis and acne as well as for anti-bacterial activity against acne-inducing pathogens. Of the four extracts, CWER was the most potent tyrosinase inhibitor ($IC_{50}$ value: $109\;{\mu}g/mL$), and CWEA ($IC_{50}:\;167\;{\mu}g/mL$) showed good antioxidative effects. CWE and CWEA samples had dose-dependent inhibitory effects on the melanin production. The cytotoxic effects of the four CPWs were determined by colorimetric MTT assays using human keratinocyte HaCaT cells. Most extracts exhibited low cytotoxicity at $100\;{\mu}g/mL$. These results suggest CPWs are attractive candidates for topical applications on the human skin.

• 한국의류산업학회지
• /
• 제19권3호
• /
• pp.302-311
• /
• 2017

The purpose of this study is to develop an aesthetic and functional bicycle wear for new senior women in their 50s and 60s. We developed bicycle wear that is friendly to bicycling posture and reflects the preference of new senior women. Both the expert group and the subject group evaluated the appearance, completeness of clothing and motion functionality. The results are as followed: First, in the evaluation result of the expert group regarding the appearance and completeness of clothing, high scores are given to design, materials, color scheme, the trends suitability as well as the appearance with regard to clothing fitness. Second, in the results of the evaluation of the appearance and movement functionality targeting the subject groups, movement functionality was rated higher than appearance. In the case of the appearance evaluation, adhesion of both jacket and pants was rated very highly, which is considered to come from the elasticity of the material. In the functionality evaluation, what were pointed out as inconvenient details in the prior studies were found to be all improved and the sleeves and armpit parts were rated highly. Therefore, the pattern design and the usage of the materials suggested in this study were found to be very suitable in the movement on the ride of bicycle.

• 시스템엔지니어링학술지
• /
• 제9권1호
• /
• pp.55-63
• /
• 2013

Nuclear power plant site selection is a complex process and its successful completion is a critical milestone in the NPP development cycle. Proper siting of NPP will ensure public health and safety, environmental conservation, reduced project failure risks and a smooth NPP development process among other benefits. The objective of this paper is to demonstrate the application of systems engineering to the problem of NPP siting in Kenya. The siting process demonstrated in this paper includes stakeholder need analysis where stakeholders are identified and their needs concerning NPP site are elicited and converted into system functional requirements. A value model is then developed and potential sites iteratively subjected to three types of criteria i.e. exclusionary criteria, avoidance criteria and suitability criteria. This process is used to identify the candidate sites. An additive value model; multiple objectives Decision Analysis (MODA) is then used to calculate candidate solutions values. The site with the highest solution value score is selected. Sensitivity studies using different criterion weight sets (thereby reflecting different viewpoints) can be conducted to assess their effect on the selection of a preferred site and thereby lend additional credibility to the decision process.