• Journal of Food Hygiene and Safety
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• v.35 no.3
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• pp.252-260
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• 2020

This study was conducted to improve the standard method for vitamin B₁₂ and biotin contained in foods for special dietary uses to ensure the specificity of the complex matrix properties of foods. For the food code, the test method was improved to determine vitamin B₁₂ and biotin by high-performance liquid chromatography (HPLC)-UV using column-switching after concentration using immunoaffinity column. The immunoaffinity columns contain a gel suspension of monoclonal antibody specific to the vitamin of interest so that it can be used to concentrate the vitamin B₁₂ and biotin and remove interferences from the food extracts. Moreover, validation of advanced new methods was carried out to support the suitability of the proposed analytical procedure (specificity, linearity, detection limits (LOD), quantitative limits (LOQ), accuracy, and precision). The improved analytical method is being used to monitor relevant food items on sale. The results of this study showed that the new analytical method is suitable and appropriate for managing food intended for special dietary uses.

• Journal of Food Hygiene and Safety
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• v.39 no.2
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• pp.72-82
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• 2024

This study aimed to develop a scientifically and systematically standardized xylooligosaccharide analytical method that can be applied to products with various formulations. The analysis method was conducted using HPLC with Cadenza C₁₈ column, involving pre-column derivatization with 1-phenyl-3-methyl-5-pyrazoline (PMP) and UV detection at 254 nm. The xylooligosaccharide content was analyzed by converting xylooligosaccharide into xylose through acid hydrolysis. The pre-treated methods were compared and evaluated by varying sonication time, acid hydrolysis time, and concentration. Optimal equipment conditions were achieved with a mobile phase consisting of 20 mM potassium phosphate buffer (pH 6)-acetonitrile (78:22, v/v) through isocratic elution at a flow rate of 0.5 mL/min (254 nm). Furthermore, we validated the advanced standardized analysis method to support the suitability of the proposed analytical procedure such as specificity, linearity, detection limits (LOD), quantitative limits (LOQ), accuracy, and precision. The standardized analysis method is now in use for monitoring relevant health-functional food products available in the market. Our results have demonstrated that the standardized analysis method is expected to enhance the reliability of quality control for healthy functional foods containing xylooligosaccharide.

• Korean Institute of Interior Design Journal
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• v.23 no.3
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• pp.56-63
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• 2014

Furniture has been developed in pursuit of human convenience and comfort, but nowadays it does not consider human users and gradually loses the essence of furniture. Especially furniture design that disregards the relation with space loses both the meaning and purpose of furniture. In this regards, it is necessary to understand the essence of furniture design and establish a design direction for future progress. Based on the relation between furniture and space, this paper intended to study on John Pawson's works that pursued the essence of design focusing on users, and propose a direction in a sense of real meaning for modern furniture design after exploring the characteristic of the furniture design of John Pawson. The study method of this paper was to investigate the design language of John Pawson and analyze his furniture in the morphological structural, functional, and material aspects. Based on such analysis, this study investigated the characteristics of the furniture design and found out what the core of the design that he pursued was. The scope of the study included the Independent Furniture that was restricted furniture collections of Driade and Spatial Furniture designed and installed at the stage of space construction. The study result showed that the design of John Pawson considered 'the suitability to a specific place' as important factor and furniture was planned at the stage of planning space. Each independent furniture defines all spaces in the morphological, lay-out and functional aspects of furniture and emphasizes their own property. As Spatial Furniture shares the function of spatial composition element, Pawson's furniture can be all called Spatial Furniture.

• Journal of the Korea Concrete Institute
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• v.24 no.2
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• pp.165-172
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• 2012

In this study, the physical, mechanical, structural, and environmental performances based on field measured data were evaluated to check the suitability of concrete for ecological preservation and cultivation of a hydrophilic environment. More specifically, the study is focused on developing an environmentally friendly functional concrete with river ecology restoration and natural river early formation capabilities. The mechanical performance evaluation results showed that the increase in mix rate of the PVA (Poly Vinyl Alcohol) reinforcement fibers and silica fume caused an increase in the strength. The optimal mix rate was found to be 0.05 volume % PVA fiber and approximately 10% silica fume. The frost resistance evaluation showed that superior performance was gained when 0.05 volume % PVA fiber and 15% silica fume was mixed simultaneously. In the structural performance evaluation, the bending strength was improved by 47.7% compared to plain concrete when mixed with 0.05 volume % PVA fiber. The flexural toughness also saw significant improvement. The environmental monitoring of field performance showed that grasses germinated most rapidly, but the growth of red poppies, a plant that germinates in the spring, was most active with passing of time. Coverage measurements in all of the monitoring locations found favorable coverage of over 95% after 12 weeks. The study results showed that the environmentally friendly functional concrete had outstanding environmental performance.

• Food Engineering Progress
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• v.14 no.2
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• pp.183-187
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• 2010

Multiple lines of study have shown that Acanthopanax species have anti-oxidant and chemopreventive effect. However, the suitability of Acanthopanax sessilifloru fruit (Ogaza) as a functional food source remains to be investigated. Therefore, we have investigated the effect of Ogaza as an anti-oxidant and anti-inflammatory substance. The phenolic content of Ogaza is 56.1${\pm}$5.2 mg gallic acid equivalents (GAE) per 1 g of Ogaza. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical scavenging effects of Ogaza extract at 0.25, 0.5, 1, or 2 mg/mL were 34.0, 73.0, 194.3, or 339.7 $\mu g$/mL vitamin C equivalent antioxidnat capacity (VCEAC), respectively. Ogaza extract (1 or 2 mg/mL) inhibited LPS-induced TNF-$\alpha$ production (decrease of 22${\pm}$2% or 19${\pm}$6%, respectively). It also inhibited LPS-induced IL-6 production (decrease of 18${\pm}$2% or 24${\pm}$3%, respectively). In addition, Ogaza extract (0.25, 0.5, 1, or 2 mg/mL) inhibited COX-2 luciferase activity (decrease of 80${\pm}$1%, 83.${\pm}$7%, 96${\pm}$4%, or 98${\pm}$2%, respectively). Overall, these results indicated that Ogaza is promising as a functional food source due to its antioxidant and anti-inflammatory effects.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.707-710
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• 2011

System safety is defined as the state where the hazard risks due to internal system, interface, operation and maintenance are controlled as acceptable levels. It is represented and evaluated either with the risk level of each risk factor with the consideration of operation environments or with Safety Integrity Level (SIL) which is the system functional safety without considering application environments. The assessment results are issued in forms of certificates and they are reused in many cases. However, the conditions and restrictions for different application environments vary in each case, therefore, additional evaluation on the preconditions of assessment in comparison with the actual application environment must be carried out. For the area of train control, TR 50506-1 has been established based on the IEC 62425 (international standard for safety of train control system by RSSB) and EN 50129 (Europe standard) for the further assessment. In this paper, the analysis on TR 5056-1 has been conducted in depth. The purpose of the study is to determine the requirements for inter-acceptability including scope, procedures, principles, examination and suitability. The results can be utilized for the system safety maintenance when new devices or components are introduced in conventional systems.

• Fashion & Textile Research Journal
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• v.17 no.4
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• pp.597-603
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• 2015

This study investigates the actual domestic and overseas cyclewear wearing conditions for male high school cyclists. The study results provide factors and degree of dissatisfaction as basic data for cyclewear development. This study was conducted on 35 male high school cyclists (freshman to seniors) by a questionnaire and interview method. Study results were: Male high school cyclists considered functionality as most important when they bought cyclewear and the brand they most often bought was a cheap domestic brand. Dissatisfaction with the crotch, thigh circumference and minimum leg circumference was higher than other parts during wearing. A cyclist is more sensitive to wear because they require more lower body motion than other parts. Cyclewear should be: less transformed even by frequent laundering, made of breathable material and use a sewing technique that minimizes air resistance and increases fit the body. Functional pads ergonomically designed with high tactile materials should be developed to prevent 'saddle sore' and groin soreness region that happens because of a lower body bending posture when cycling. A follow-up study is recommended to further develop excellence in cyclewear functionality and dimension suitability for male high school cyclists through the size system.

• Journal of Applied Biological Chemistry
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• v.51 no.1
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• pp.7-12
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• 2008

The suitability of CPWs, by-products of the juice industry, was investigated as a source for the production of cosmeceuticals. Four kinds of CPWs, CW, CWE, CWER, and CWEA, were examined for their antioxidant potentials in terms of DPPH radical-scavenging ability for anti-wrinkle applications, inhibition of tyrosinase or melanin production for whitening products, and anti-inflammatory effects to treat various skin diseases such as atopic dermatitis and acne as well as for anti-bacterial activity against acne-inducing pathogens. Of the four extracts, CWER was the most potent tyrosinase inhibitor ($IC_{50}$ value: $109\;{\mu}g/mL$), and CWEA ($IC_{50}:\;167\;{\mu}g/mL$) showed good antioxidative effects. CWE and CWEA samples had dose-dependent inhibitory effects on the melanin production. The cytotoxic effects of the four CPWs were determined by colorimetric MTT assays using human keratinocyte HaCaT cells. Most extracts exhibited low cytotoxicity at $100\;{\mu}g/mL$. These results suggest CPWs are attractive candidates for topical applications on the human skin.

• Fashion & Textile Research Journal
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• v.19 no.3
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• pp.302-311
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• 2017

The purpose of this study is to develop an aesthetic and functional bicycle wear for new senior women in their 50s and 60s. We developed bicycle wear that is friendly to bicycling posture and reflects the preference of new senior women. Both the expert group and the subject group evaluated the appearance, completeness of clothing and motion functionality. The results are as followed: First, in the evaluation result of the expert group regarding the appearance and completeness of clothing, high scores are given to design, materials, color scheme, the trends suitability as well as the appearance with regard to clothing fitness. Second, in the results of the evaluation of the appearance and movement functionality targeting the subject groups, movement functionality was rated higher than appearance. In the case of the appearance evaluation, adhesion of both jacket and pants was rated very highly, which is considered to come from the elasticity of the material. In the functionality evaluation, what were pointed out as inconvenient details in the prior studies were found to be all improved and the sleeves and armpit parts were rated highly. Therefore, the pattern design and the usage of the materials suggested in this study were found to be very suitable in the movement on the ride of bicycle.

• Journal of the Korean Society of Systems Engineering
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• v.9 no.1
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• pp.55-63
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• 2013

Nuclear power plant site selection is a complex process and its successful completion is a critical milestone in the NPP development cycle. Proper siting of NPP will ensure public health and safety, environmental conservation, reduced project failure risks and a smooth NPP development process among other benefits. The objective of this paper is to demonstrate the application of systems engineering to the problem of NPP siting in Kenya. The siting process demonstrated in this paper includes stakeholder need analysis where stakeholders are identified and their needs concerning NPP site are elicited and converted into system functional requirements. A value model is then developed and potential sites iteratively subjected to three types of criteria i.e. exclusionary criteria, avoidance criteria and suitability criteria. This process is used to identify the candidate sites. An additive value model; multiple objectives Decision Analysis (MODA) is then used to calculate candidate solutions values. The site with the highest solution value score is selected. Sensitivity studies using different criterion weight sets (thereby reflecting different viewpoints) can be conducted to assess their effect on the selection of a preferred site and thereby lend additional credibility to the decision process.