• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.5
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• pp.565-570
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• 2014

The purpose of this study is to report a clinical case of a patient with CIPN (Chemotherapy Induced Peripheral Neuropathy) successfully treated with Korean medicine interventions including acupuncture, herbal medicine and moxibustion. The patient is a female with CIPN who was diagnosed with ascending colon cancer and suffering from paresthesia of extremities after chemotherapy of platinum compounds. The patient was treated mainly with electroacupuncture (Ex-LE 10), indirect moxibustion and herbal medicine (Ucha-Shinki-hwan granule). The clinical outcomes were measured by NCI CTCAE grade, EORTC QLQ-C30 (CIPN20) scale and patient's assessment of symptoms. In this case, the NCI CTCAE grade was improved from II to I. The scores of global health status and functional scale in QLQ-C30 were increased and symptom scale was decreased. Especially, this case shows a noticeable decrease in sensory scale in QLQ-CIPN20. In patient's general assessment, the scale was changed from 10 to 5. Korean medical interventions including acupuncture, herbal medicine and moxibustion could potentially be an effective treatment for CIPN if further researches are conducted.

• Food Science and Preservation
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• v.22 no.2
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• pp.267-274
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• 2015

This study was conducted to evaluate the antioxidant activities and the quality characteristics of 70% ethanol extracts from onion peels with different extraction methods (autoclave extraction, AE; low temperature high pressure extraction, LTPE; reflux extraction, RE; and stirrer extraction, SE). The yields of AE, LTPE, RE and SE were 9.00%, 5.39%, 13.21% and 12.41%, respectively. The total polyphenol and flavonoid contents in the AE were significantly higher than in the other extracts. The DPPH radical scavenging abilities with a concentration of 100 mg% (w/v) were : AE, 28.9%; RE, 26.07%; LTPE, 24.35%; and SE, 19.53%. The ABTS radical scavenging ability and the nitrite scavenging activity showed the same tendency as that of the DPPH radical scavenging ability. The angiotensin-converting enzyme (ACE) inhibitory activities of the LTPE and AE were higher than those of the RE and SE. The ${\alpha}$-Glucosidase inhibitory activity of the RE was higher than that of the extracts with other extraction methods. The nitrite scavenging activities with a concentration of 10 mg/mL were: AE. 33.97%; RE, 35.47%; LTPE, 21.86%; and SE, 21.71%. The ferrous ion chelating activity of the LTPE (54.73%) was significantly higher than that of the other extracts. These results suggest that AE is the superior method for the enhancement of anti-oxidant activity, and onion peel can be used as a natural antioxidant material for health foods and can be a good ingredient of functional foods.

• Journal of the Korean Society of Clothing and Textiles
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• v.28 no.12 s.138
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• pp.1554-1561
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• 2004

In the U.S., outdoor enthusiasts such as golfers have been focused on skin cancer prevention practices since their outdoor activities lead to extensive sun exposure during peak sun hours. The purposes of this study were to investigate golfers current sun protection behaviors and five attributes and their impacts on the intention to adopt UV specialized clothing based on Rogers' theory. UV specialized clothing as a preventive innovation is related to sun protection behaviors. However, there has been little effort to explain the intention to adopt a preventive innovation regarding health-related practices. With a convenience sampling method, a total of 158 useful questionnaires were collected. Ninety one percent were male golfers, and their age ranged from 16 to 80 years old(mean age=30 years). About $25\%$ reported to practice sun protection behaviors. About $70\%$ disagreed on the relative advantage, compatibility, observability, and triability of UV specialized shirts and reported the low intention to purchase it. Current sun protection behaviors and five attribute variables were entered in the multiple regression equation to explain the dependent variable of intention to adopt the innovation. Triability was the best predictor of the intention to adopt UV specialized shirts, followed by current sun protection behaviors, compatibility, and relative advantage. With four predictors, $45\%$ of the variance of intention to adopt was explained. The present study provides how the golfers current sun protection behaviors play important roles in explaining the intention to adopt the preventive innovation. Physical and functional features of UV specialized clothing were also significantly associated with their intentions to adopt it.

• Food Science and Preservation
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• v.17 no.3
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• pp.343-350
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• 2010

Cheongkukjang was prepared by addition of medicinal herb powder (from Lentinus edodes, Codonopsis lanceolata BENTH et HOOK, or Houttuynia cordata THUNB) to improve Cheongkukjang quality and functional properties. Redness and yellowness (measured using Hunter’s color values) increased with increasing amounts of medicinal herb powder, whereas lightness (the third Hunter's color value) and pH decreased. Crude protein and lipid levels of Cheongkukjang decreased with increasing amounts of added medicinal herb powder, whereas powder addition did not affect either the moisture or crude ash content of Cheongkukjang. The major organic acids of Cheongkukjang were lactic acid, acetic acid, succinic acid, and citric acid, and acid levels increased as the proportion of medicinal herb powder in the Cheongkukjang preparation increased. The major amino acids of Cheongkukjang were glutamic acid, aspartic acid, leucine, arginine, and lysine and the principal fatty acids were linoleic acid, oleic acid, palmitic acid, and linolenic acid. Addition of medicinal herb powder to Cheongkukjang increased both crude saponin and quercetin contents. Sensory scores of Cheongkukjang containing 2% (w/v) medicinal herb powder were optimal in terms of both quality characteristics and sensory evaluation.

• Journal of Life Science
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• v.25 no.8
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• pp.917-924
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• 2015

This study aimed to evaluate the protective effect of Orostachys malacophyllus (OM) and fermented O. malacophyllus (FOM) in Sprague-Dawley rats who had been intoxicated with 1% (w/w) orotic acid (OA) for 10 days. The activities of several hepatic enzymes, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and cholinesterase, were increased when OA was given, but these parameters were significantly decreased by FOM treatment. In addition, OA treatment resulted in an increased lipid peroxidative index (thiobarbituric acid-reactive substances, TBARS). A worsened antioxidant status (reduced glutathione) in the liver and serum was also observed. FOM treatment improved the antioxidant status of OA-induced fatty-liver rats, which was evaluated by decreased levels of the lipid peroxidative index and improved antioxidant status in the liver and serum. The contents of liver non-heme iron were increased with OA treatment and significantly decreased with FOM treatment, which suggested that the lipid peroxidation contents were inversely correlated with liver non-heme iron content. Based on these results, FOM is considered a material with significant potential for development into a functional health food that can improve fatty-liver conditions.

• Journal of Korean Society for Atmospheric Environment
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• v.30 no.4
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• pp.327-338
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• 2014

The objective of this study is to enhance the effectiveness of Korean Inspection and Maintenance (I/M) program. Three main tasks are: to measure pollutant emissions of in-use light-duty diesel vehicles (LDVs); to evaluate the validity of existing smoke control scheme for low-smoke-emitting vehicles, which have diesel particulate filters, DPF, to meet stringent Euro-5 emission limits; and to assess the necessity and the benefit of $NO_x$ inspection, which is not involved in current I/M program. We measured second-by-second smoke, particulate and gaseous emissions of 27 LDVs using opacity smoke meter, photo-acoustic soot sensor, and portable emissions measurement system, respectively, under the Korean I/M test driving cycle, KD-147. We find that the DPF plays a key role in controlling soot, which can be considered as black carbon contained in particulate matter. Thus, from an I/M perspective, we believe smoke inspection strategies for Euro-5 diesel vehicles should be more focused on the capability of detecting DPF malfunctions or failures, in order to keep DPF properly functional. Fleet averaged distance-specific $NO_x$ emissions are consistently higher than corresponding emission limits, and the values are similar among pre-Euro-3, Euro-3, and Euro-4 vehicle fleets. These findings indicate that the $NO_x$ inspection should be incorporated into current I/M program in order to manage urban $NO_x$ emissions. This research allows the Korean I/M program keep pace with developments in vehicle technologies, as well as the increased emphasis on $NO_x$ with respect to air quality and human health.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.59 no.1
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• pp.16-21
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• 2014

Yield, growth characteristics, free radical-scavenging capacities, total phenolic contents and free amino acids contents were determined in Amaranthus species grown in Korea. And this study was aimed to investigate the functional properties of Amaranthus in two regions(Gangneung and Daegwallyeong). Yield ranged from 125 to 465 kg $10a^{-1}$ and RRC 1027 was the highest yield. Amaranthus seed size was very small, average seed weight(1,000 seeds) varied 0.42~0.82 g, especially Kerala Red was the most light weight. In DPPH (1,1-diphenyl-2-picryl hydrazyl) radical scavenging activity, there is no significantly different between growing regions but colored Kerala Red was the highest among varieties. The total amount of phenolic compounds varied from 994 to 1,732 mg/kg. Among amino acids of seeds, the contents were in order of glutamic acid(30.5 mg $100g^{-1}$) > aspartic acid (26.1 mg $100g^{-1}$) > arginine(24.3 mg $100g^{-1}$). The present study shows that South Korea is suitable for the cultivation of Amaranthus. Common grains lack glutamic acid, aspartic acid and arginine we need for optimal health, but Amaranthus contains these amino acids. Amaranthus is great potential to develop new crop. But for measurement of antioxidant activity, in addition to DPPH method we are looking the other way.

• Korean Journal of Environmental Agriculture
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• v.34 no.2
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• pp.105-110
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• 2015

BACKGROUND: Soy isoflavones, structurally similar to endogenous estrogens, may affect human body through both hormonally mediated and non-hormonally related mechanisms. Heat processing could change chemical compositions. The effects of different thermal processes, boiling and HTHP(high temperature and high pressure) on the composition of isoflavone compounds and total amount of domestic soybeans were investigated in this study. METHOD AND RESULTS: Three different kinds of soybean samples were collected from RDA-Genebank. The samples were extracted using methanol, distilled water, and formic acid based solvent. Also the same solvents were used for mobile phase in UPLC/ToF/MS. All of the isoflavone compounds were analyzed based on the aglycone type of external standard for quantification. The standard calibration curve presented linearity with the correlation coefficient R2 > 0.98, analysed from 1 to 50 ppm concentration. The total isoflavone contents does not change by treatment within the same breed. While "boiling" and "HTHP" processes tend to increase the contents of aglycone and ${beta}$-glucosides, "fresh" soybeans retained the high concentration of malonylglucosides. CONCLUSION: These results have to be considered while developing an effective functional food, from the health while point of view using soybeans.

• Journal of Life Science
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• v.22 no.2
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• pp.251-258
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• 2012

The purpose of this study was to investigate the probiotic properties of lactic acid bacterial strains isolated from animal feces. BCNU 9041 and BCNU 9042 isolates were assigned to Lactobacillus brevis on the basis of their physiological properties and 16S ribosomal DNA sequences analysis. They were confirmed as safe bioresources because of their non-hemolytic activities and non-production of harmful ${\beta}$-glucosidase, ${\beta}$-glucuronidase, tryptophanase, or urease. These isolates were also highly resistant to acid (at pH 2.5) and bile acids (at concentration of 0.3%, 0.6%, and 1% oxgall). In addition, they exhibited good antibacterial activity against food-borne bacteria, especially Bacillus cereus, Listeria monocytogenes, and Shigella sonnei. Furthermore, it was demonstrated that they have the highest levels of hydrophobicity and that they showed bile salt hydrolytic and cholesterol assimilation activity. These results suggest that BCNU 9041 and 9042 have good potential for application in functional foods and health-related products.

• Journal of the East Asian Society of Dietary Life
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• v.22 no.5
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• pp.677-683
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• 2012

The characteristics and preservation of sulgi added with 0, 1, 3, and 5% onion juice were investigated during storage at $4^{\circ}C$, $18^{\circ}C$, and $30^{\circ}C$. The pH of sulgi added with onion juice was lower than that of sulgi without onion juice and showed higher pH levels at $4^{\circ}C$ than at $18^{\circ}C$ or $30^{\circ}C$. Hardness of sulgi gradually decreased with higher volume of onion juice. Sulgi added with onion juice had higher values of lightness and yellowness than those of the control, whereas redness value was lower. Water activity of sulgi increased upon addition of onion juice. Further, addition of onion juice inhibited growth of aerobic bacteria and mold on sulgi, and the highest suppression of microbial growth was observed at $4^{\circ}C$ compared to other storage temperatures. In the sensory evaluation, color, flavor, after swallowing, and overall quality were all higher in sulgi containing 1% onion juice, but there were no significant differences compared to control sulgi. These results imply that addition of onion juice to sulgi has health and functional benefits and also extends the self-life of sulgi.