• Investigative Magnetic Resonance Imaging
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• 제4권1호
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• pp.14-19
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• 2000

목적 : 뇌열환자에서 기능적 자기공명영상과 경두부 자기자극을 이용하여 뇌기능을 지도화하고자하였다. 대상 및 방법: 자기공명영상에서 우측 대뇌반구에 뇌열 소견이 있으며 좌측 편측부전마비를 보인 28세 남자환자를 대상으로 기능적 자기공명영상과 경두부 자기자극을 시행하였다. 임상적으로 좌측 손의 운동기능은 감소되어 있었고, 우측 손의 운동기능은 정상범주에 속하였다. 뇌기능적 자기공명영상은 EPI 기법을 이용하였고 운동자극은 1-2 Hz의 주기로 손가락을 아래위로 구부리게 하는 운동을 시행하였고 15초의 휴식기와 15초의 운동기를 반복하여 절편당 60 개의 영상을 획득하였다. 두부자기자극은 지름 90mm의 원형 자성자극기를 이용하여 maximal out-put의 80%로 자극하여 양측 단무지 외 전근에서 유발된 운동유발전위의 잠시와 진폭을 구하였다. 결과: 기능적 자기공명영상을 시행한 결과 정상적인 우측손의 운동자극시에 좌측 운동피질이 활성화되었고 좌측손의 운동자극시에는 좌측운동피질, 좌측 부가운동영역, 그리고 자측 전운동영역에 활성화소견이 나타났다. 두부자기자극에서는 우측 대뇌반구에서는 한군데에서도 운동유발 전위가 발생되지 않았다. 좌측 대뇌반구에서는 5군데에서 운동유발전위가 유발되었으며 모두 양측 단무지 외 전근에서 운동유발전위가 유발되었다. 양손에서 운동유발전위의 잠시 , 진폭 모양이 유사하였다. 결론: 뇌열환자의 손운동기능의 피지도화는 기능적 자기공명영상과 두부자기자극을 이용하여 성공적으로 시행할 수 있었다. 뇌열환자의 동측 운동경로는 동일한 운동피질로부터 기원한 동측피질척수로에 의한 것으로 추정된다.

• The Journal of Korean Physical Therapy
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• 제22권2호
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• pp.7-13
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• 2010

Purpose: This study was designed to determine the correlation between faster response time and functional activities of brain regions during cognitive time management. Methods: Twelve healthy subjects participated in this experiment. Subjects performed the serial reaction time task (SRTT), which was designed by the Superlab program, during fMRI scanning. When the 'asterisk' appeared in the 4 partition spaces on the monitor, the subject had to press the correct response button as soon as possible. Results: fMRI results showed activation of the left primary sensorimotor cortex, both premotor areas, the supplementary motor area, posterior parietal cortex and cerebellum. There were significant correlations, from moderate to strong, between faster reaction time and BOLD signal intensity in activated areas. Conclusion: These results suggest that motor skill learning to be needed cognitive time management is associated with greater activation of large scale sensorimotor networks.

• 한국군사과학기술학회지
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• 제13권3호
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• pp.421-430
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• 2010

This work describes a derivation process of JIC(Joint Integrating Concept) based JFC(Joint Functional Concept) analysis of an Aegis BMD(Ballistic Missile Defense). JIC is developed through JOC(Joint Operating Concept) and JFC based on capstone strategy and concept. Aegis BMD is a sea-based ballistic missile defense to detect ballistic missile threat, increase engagement battlespace and enable multiple engagement based on Aegis ships. Aegis BMD is a good case of JIC due to performing an Joint operations based on System of Systems under highly complicated NCW environment. This work analyses JFC using QFD(Quality Function Deployment) and UJTL(Universal Joint Task List). From this analysis the JIC of Aegis Korean BMD is derived using a CASE tool.

• 한국멀티미디어학회논문지
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• 제24권2호
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• pp.295-304
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• 2021

Learning assistance system that continuously measures user's concentration will be helpful to grasp the concentration pattern and adjust the learning method accordingly to improve the learning efficiency. Although a lot of various learning aids have been proposed, there have been few studies on the concentration monitoring system in real time. Therefore, in this study, we developed an Android-based mobile application that can measure concentration during study by using functional near-infrared spectroscopy, which is used to measure brain activity. First, the task accuracy was predicted at a maximum level of 93.75% from the prefrontal oxygenation characteristics measured while performing the visual Q&A task on 11 college students, and a concentration calculation formula based on a linear regression model was derived. Then, a survey on the usability of the mobile application was conducted, overall high satisfaction and positive opinions were obtained. From these findings, this application can be used as a customized learning aid application for users, and further, it can help educators improve the quality of classes based on the level of concentration of learners.

• The Korean Journal of Physiology and Pharmacology
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• 제12권5호
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• pp.245-251
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• 2008

Single-channel recordings of TASK-1 and TASK-3, members of two-pore domain $K^+$ channel family, have not yet been reported in dorsal root ganglion (DRG) neurons, even though their mRNA and activity in whole-cell currents have been detected in these neurons. Here, we report single-channel kinetics of the TASK-3-like $K^+$ channel in DRG neurons and up-regulation of TASK-3 mRNA expression in tissues isolated from animals with spinal cord injury (SCI). In DRG neurons, the single-channel conductance of TASK-3-like $K^+$ channel was $33.0{\pm}0.1$ pS at - 60 mV, and TASK-3 activity fell by $65{\pm}5%$ when the extracellular pH was changed from 7.3 to 6.3, indicating that the DRG $K^+$ channel is similar to cloned TASK-3 channel. TASK-3 mRNA and protein levels in brain, spinal cord, and DRG were significantly higher in injured animals than in sham-operated ones. These results indicate that TASK-3 channels are expressed and functional in DRG neurons and the expression level is up-regulated following SCI, and suggest that TASK-3 channel could act as a potential background $K^+$ channel under SCI-induced acidic condition.

• 한국콘텐츠학회논문지
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• 제12권3호
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• pp.222-232
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• 2012

본 연구는 슬관절 전치환술을 시행하고 난 후 3주 이내의 환자 24명에게 과제 지향 훈련과 체중 이동 훈련이 정적 균형과 동적 균형에 어떠한 영향을 미치는지 알아보기 위해서 실시하였다. 대상자는 과제 지향 훈련군(실험군) 12명과 체중 이동 훈련군(대조군) 12명을 2그룹으로 무작위 배정하였다. 각 군의 운동 효과를 알아보기 위하여 Gaitview 시스템과 기능적 팔 뻗기 검사를 통해 정적 균형을 측정하였고, Balance 시스템을 이용하여 동적 균형을 측정하였다. 통계 분석은 실험 전과 후의 차이를 알아보기 위하여 대응표본 t검정을 실시하였고, 그룹 간 차이를 알아보기 위하여 독립표본 t검정을 실시하였다. 그 결과 과제 지향 훈련군이 체중 이동 훈련군에 비해 정적, 동적 균형 능력에 유의한 차이를 보였다(p<0.05). 따라서 이번 연구 결과를 통해 슬관절 전치환술을 시행한 조기 환자들에게 과제 지향 훈련이 균형 능력에 효과적이라는 것을 알 수 있었다.

• The Journal of Korean Physical Therapy
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• 제21권4호
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• pp.23-30
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• 2009

Purpose: This study investigated the efficacy of task-related circuit training aimed at improving balance in individuals discharged from rehabilitation facilities following a stroke. Methods: We recruited 12 stroke patients (34-66 years of age) to participate in a task-related circuit training program. Baseline assessment included a history of stroke and an assessment using the Mini-Mental State Examination Korea (MMSE-K). After a baseline assessment, follow-up assessments were administered pre- and post-training. These included Berg Balance Scale (BBS), Functional Reach Test (FRT), and the Time Up & Go Test (TUG). Physiotherapists trained study subjects under the one-to-one supervision of students from the department of physical therapy. Circuit class study participants attended 90-minute treatment sessions, one day a week for 12 weeks (from September to December 2008). The program consisted of a light warm-up period (10 min), physical exercises for improving balance (20 min), tasks focused on improving balance (50 min) and a cool-down period (10 min). Results: Scores for the BBS assessment increased significantly (from 43.2 to 49.7) after the training (p<0.05). Reach distance on the FRT increased substantially (from 27.7 cm to 47.0 cm), although the improvement was not significant (p>0.05). The average time on the TUG test decreased significantly (from 23.7 sec to 19.5 sec) after the training (p<0.05). Conclusion: The task-related circuit training program improved the balance and mobility of subjects, indicating that such a group program is useful for stroke patients who are discharged from the hospital. More such task-related programs set in a community environment should be developed.

• 한국산학기술학회논문지
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• 제17권1호
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• pp.274-283
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• 2016

본 논문은 복잡해지는 군수분야에서 효율적이고 효과적인 예방정비업무 할당을 위해 Hard Time업무의 최적 주기산정 및 이를 통한 경제적 효용성을 분석하는데 연구 목적이 있다. 본 연구는 기존 연구에서 제시하는 예방정비 주기 선정방법의 한계점을 분석하였다. 또한 일반적인 Wearout 고장 특성을 설명하는 와이블 수명분포에서 다양한 형상모수 조건과 예방정비비용과 고장정비비용 조건을 가정한 시뮬레이션을 통해 가상의 시스템에 대한 정비활동을 모의하여 총 정비비용의 추의를 분석하였다.

• 대한물리의학회지
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• 제18권2호
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• pp.41-48
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• 2023

PURPOSE: Falls are caused by a decline in physical and cognitive function. A quantitative evaluation tool that can comprehensively evaluate motor and cognitive functions for elderly people with an impaired physical function. This study assessed the clinical application potential by confirming the correlation between the physical function tests, cognitive and the stepping trail-making test (S-TMT). METHODS: Fourteen community-dwelling older patients (65-75 years) were recruited. The study conducted cognitive function tests with the trail-making test (TMT-A, B), and physical function tests (6-minute walking test (6MWT), short physical performance battery (SPPB), and timed up and go (TUG)). The results of were analyzed using SPSS version 21.0. Descriptive statistics were used for the general characteristics of the study subjects, and the correlations between S-TMT, other functional tests were examined through Pearson's correlation analysis. The statistical significance was set to .05. RESULTS: S-TMT had a significant positive correlation with the TUG (r = .588^*) and trail-making test-B (TMT-B) (r = .689^*, p < .05). Furthermore, S-TMT showed a negative correlation between SPPB (r = -.397) and 6MWT (r = -.422), but it was not statistically significant. CONCLUSION: S-TMT is a cognitive-gait dual-task performance evaluation tool that can be performed safely. A significant correlation was confirmed between the TUG test and the TMT-B. S-TMT is a dual-task screening tool that can evaluate both physical and cognitive functions simultaneously.

• 한국CDE학회논문집
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• 제5권4호
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• pp.359-372
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• 2000

Current CAD systems are good enough to be used as a tool to manipulate three-dimensional shapes. This is a very important capability to be owned by a design tool because a major portion of designers'activities is spent on the shape manipulation in the design detailing process. However, the whole design process involves a lot more than the, shape manipulation. Currently, these remaining tasks, mostly logical reasoning process for the function realization together with structure decomposition in the top-down manner, are processed in the designer's brain. To support the top-down functional design process of a mechanical product, a system integrating the functional, structural and geometrical aspects of a product design in a unified environment is presented. Using this system, a designer can perform function decomposition, structure decomposition, and geometry detailing, and function verification activities in parallel and the whole design process it modeled resultantly. Once the whole design process is modeled, any redesign task can be automatically performed with the verification of the desired functions.