• 한국군사과학기술학회지
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• 제20권2호
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• pp.225-230
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• 2017

To generate mechanical movements in one-shot devices such as missiles and space launch vehicles, pyrotechnic mechanical device(PMD) such as pin pullers using pyrotechnic charge has been widely used. Reliability prediction of pin pullers is crucial to successfully execute target missions for the one-shot devices. Because the pin pullers require destructive tests to evaluate their reliability, one would need about 3,000 samples of success to guarantee a reliability of 99.9 % with a confidence level of 95 %. This paper suggests the application of a probit model using the charge amount as a functional parameter for estimation of functional reliability of pin puller. To guarantee target reliability, we propose estimation methods of the lower bound of functional reliability by applying the probit model. Given lower bound of functional reliability, we quantitatively show that the optimum amount of charge increases as the number of samples decreases. Along with a variety of simulations the validity of our new model via real test results is confirmed.

• ETRI Journal
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• 제21권3호
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• pp.6-15
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• 1999

Many studies in the software reliability have attempted to develop a model for predicting the faults of a software module because the application of good prediction models provides the optimal resource allocation during the development period. In this paper, we consider the change request data collected from the field test of the software module that incorporate a functional relation between the faults and some software metrics. To this end, we discuss the general aspect if regression method, the problem of multicollinearity and the measures of model evaluation. We consider four possible regression models including two stepwise regression models and two nonlinear models. Four developed models are evaluated with respect to the predictive quality.

• Journal of Biosystems Engineering
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• 제30권6호통권113호
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• pp.360-365
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• 2005

Precision agriculture attempts to improve cropping efficiency by variable application of crop treatments such as fertilizers and pesticides, within field on a point-by-point basis. Therefore, a more complete understanding of the relationships between yield and soil properties is of critical importance in precision agriculture. In this study, the functional relationships between measured soil properties and rice yield were investigated. A supervised back-propagation neural network model was employed to relate soil chemical properties and rice yields on a point-by point basis, within individual site-years. As a results, a positive correlation was found between practical yields and predicted yields in 1999, 2000, 2001, and 2002 are 0.916, 0.879, 0.800 and 0.789, respectively. The results showed that significant overfitting for yields with only the soil chemical properties occurred so that more of environmental factors, such as climatological data, variety, cultivation method etc., would be required to predict the yield more accurately.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1998년도 제13차 학술회의논문집
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• pp.445-450
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• 1998

In this paper, a robust nonlinear prediction-type controller (RNPC) is developed for the continuous time nonlinear system whose control objective is composed of system output and its desired value. The basic control law of RNPC is derived such that the future response of the system is first predicted by appropriate functional expansions and the control law minimizing the difference between the predicted and desired responses is then calculated. RNPC which involves two controls, i.e., the auxiliary and robust controls into the basic control, shows the stable closed loop dynamics of nonlinear system of any relative degree and provides the robustness to the nonlinear system with parameter/modeling uncertainty. Simulation tests for the position control of a two-link rigid body manipulator confirm the performance improvement and the robustness of RNPC.

• Genomics & Informatics
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• 제21권2호
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• pp.25.1-25.12
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• 2023

Adaptation of infections and hosts has resulted in several metabolic mechanisms adopted by intracellular pathogens to combat the defense responses and the lack of fuel during infection. Human tuberculosis caused by Mycobacterium tuberculosis (MTB) is the world's first cause of mortality tied to a single disease. This study aims to characterize and anticipate potential antigen characteristics for promising vaccine candidates for the hypothetical protein of MTB through computational strategies. The protein is associated with the catalyzation of dithiol oxidation and/or disulfide reduction because of the protein's anticipated disulfide oxidoreductase properties. This investigation analyzed the protein's physicochemical characteristics, protein-protein interactions, subcellular locations, anticipated active sites, secondary and tertiary structures, allergenicity, antigenicity, and toxicity properties. The protein has significant active amino acid residues with no allergenicity, elevated antigenicity, and no toxicity.

• Bulletin of the Korean Chemical Society
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• 제34권4호
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• pp.1043-1046
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• 2013

Prediction of physicochemical properties of organic molecules is an important process in chemistry and chemical engineering. The MSEP approach developed in our lab calculates the molecular surface electrostatic potential (ESP) on van der Waals (vdW) surfaces of molecules. This approach includes geometry optimization and frequency calculation using hybrid density functional theory, B3LYP, at the 6-31G(d) basis set to find minima on the potential energy surface, and is known to give satisfactory QSPR results for various properties of organic molecules. However, this MSEP method is not applicable to screen large database because geometry optimization and frequency calculation require considerable computing time. To develop a fast but yet reliable approach, we have re-examined our previous work on organic molecules using two semi-empirical methods, AM1 and PM3. This new approach can be an efficient protocol in designing new molecules with improved properties.

• KSBB Journal
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• 제26권2호
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• pp.131-138
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• 2011

Some computational approaches are needed for clarifying RNAi sequences, because it takes much time and endeavor that almost of RNAi sequences are verified by experimental data. Incorrectness of RNAi mechanism and other unaware factors in organism system are frequently faced with questions regarding potential use of RNAi as therapeutic applications. Our massive parallelized pair alignment scoring between dsRNA in Genebank and expressed sequence tags (ESTs) in Caenorhabditis elegans Genome Sequencing Projects revealed that this provides a useful tool for the prediction of RNAi induced cosuppression details for practical use. This pair alignment scoring method using high performance computing exhibited some possibility that numerous unwanted gene silencing and cosuppression exist even at high matching scores each other. The classifying the relative higher matching score of them based on GO (Gene Ontology) system could present mapping dsRNA of C. elegans and functional roles in an applied system. Our prediction also exhibited that more than 78% of the predicted co-suppressible genes are located in the ribosomal spot of C. elegans.

• Journal of Hospice and Palliative Care
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• 제26권1호
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• pp.1-6
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• 2023

This paper aimed to summarize the current situation of prognostication for patients with an expected survival of weeks or months, and to clarify future research priorities. Prognostic information is essential for patients, their families, and medical professionals to make end-of-life decisions. The clinician's prediction of survival is often used, but this may be inaccurate and optimistic. Many prognostic tools, such as the Palliative Performance Scale, Palliative Prognostic Index, Palliative Prognostic Score, and Prognosis in Palliative Care Study, have been developed and validated to reduce the inaccuracy of the clinician's prediction of survival. To date, there is no consensus on the most appropriate method of comparing tools that use different formats to predict survival. Therefore, the feasibility of using prognostic scales in clinical practice and the information wanted by the end users can determine the appropriate prognostic tool to use. We propose four major themes for further prognostication research: (1) functional prognosis, (2) outcomes of prognostic communication, (3) artificial intelligence, and (4) education for clinicians.

• 시스템엔지니어링학술지
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• 제19권1호
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• pp.107-113
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• 2023

For one-shot systems such as 81mm high-explosive ammunition, research on performance prediction is insignificant due to research manpower infrastructure and lack of interest and difficulties in securing field data, which can only be done by special task workers. In order to evaluate the actual range of ammunition, the storage ammunition reliability evaluation checks the range by firing actual ammunition through a functional test. Test evaluation is a method of extracting a sample from the population, launching it, and recording the results accordingly. As a result of these tests, the range, which is an indicator of ammunition performance, can be measured differently according to meteorological factors such as temperature, atmospheric pressure, and humidity according to the location of the test site. In this study, various environmental factors generated at the test site and storage period analyze the correlation with the range, which is the performance of ammunition, and analyze the priority of importance for each factor and the numerical standards that environmental factors affect range. Through this, a new approach to one-shot system performance prediction was presented.

• Archives of Plastic Surgery
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• 제41권2호
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• pp.174-180
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• 2014

It is well known that patients with severe facial injuries accompanied by facial disfiguration are vulnerable to a poor quality of life. With the help of facial transplantation, it has become possible to achieve an optimal anatomical reconstruction. As compared to conventional methods, it can provide more desirable functional, aesthetic, and psychosocial outcomes. Face transplantation surgeons need to consider many problems associated with the criteria for selecting patients, techniques for harvesting the donor tissue, prediction of the expected functional outcomes, limitations in obtaining written informed consent for conducting the procedure, evaluation of the post-transplant immunological response and postoperative immunosuppressant requirements, psychological and social outcomes for the patients, and other concerns about funding and ethical issues.