• 제목/요약/키워드: Full-text Database

검색결과 73건 처리시간 0.025초

PubMed 검색을 통한 항암화학요법 부작용 관련 침 임상시험 현황 고찰 (Review on Clinical Trials of Chemotherapy Induced Toxicity with Acupuncture in PubMed Database)

  • 김종윤;김진엽;김남식;김소정;뭉흐게렐;김용석;최도영;남상수
    • Journal of Acupuncture Research
    • /
    • 제30권2호
    • /
    • pp.43-53
    • /
    • 2013
  • Objectives : The purpose of this study is to review of Clinical trials related to the treatment of chemotherapy induced-toxicity by acupuncture therapy. Methods : We searched PubMed by using word of "chemotherapy induced, acupuncture" (Limits : Full text available, 10 years, Clinical trials, Humans, English). We analyzed 15 research paper and examined published journals, years, countries, topic, study design, their results, interventions, participants and instruments of assessment. Results : Eleven journals with fifteen papers were searched. These papers were published in USA, Germany, etc. On the topic of these clinical trials, seven of them were about nausea(vomiting), two about peripheral neuropathy, two about hot flash, two about arthralgia and one about neutropenia, one about fatigue. Six of these studies were single blinded, randomized controlled trial. Twelve studies reported significant effect. The median for number of final participants was 35.5 persons. Assessment for outcomes were versatile questionnaire, nerve conduction studies, WBC, ANC, G-CSF examination, etc. Conclusions : Their median for impact factor was 3.650 and average modified Jadad score of six RCTs was 4.33. In order to provide appropriate evidence regarding the effectiveness of acupuncture in treatment for chemotherapy-induced toxicity, more rigorous and well-designed studies are necessary.

Resistance to sliding in orthodontics: misconception or method error? A systematic review and a proposal of a test protocol

  • Savoldi, Fabio;Papoutsi, Aggeliki;Dianiskova, Simona;Dalessandri, Domenico;Bonetti, Stefano;Tsoi, James K.H.;Matinlinna, Jukka P.;Paganelli, Corrado
    • 대한치과교정학회지
    • /
    • 제48권4호
    • /
    • pp.268-280
    • /
    • 2018
  • Resistance to sliding (RS) between the bracket, wire, and ligature has been largely debated in orthodontics. Despite the extensive number of published studies, the lack of discussion of the methods used has led to little understanding of this phenomenon. The aim of this study was to discuss variables affecting RS in orthodontics and to suggest an operative protocol. The search included $PubMed^{(c)}$, $Medline^{(c)}$, and the Cochrane $Library^{(c)}$. References of full-text articles were manually analyzed. English-language articles published between January 2007 and January 2017 that performed an in vitro analysis of RS between the bracket, wire, and ligature were included. Study methods were analyzed based on the study design, description of materials, and experimental setup, and a protocol to standardize the testing methods was proposed. From 404 articles identified from the database search and 242 records selected from published references, 101 were eligible for the qualitative analysis, and six for the quantitative synthesis. One or more experimental parameters were incompatible and a meta-analysis was not performed. Major factors regarding the study design, materials, and experimental setup were not clearly described by most studies. The normal force, that is the force perpendicular to the sliding of the wire and one of the most relevant variable in RS, was not considered by most studies. Different variables were introduced, often acting as confounding factors. A protocol was suggested to standardize testing procedures and enhance the understanding of in vitro findings.

국내 보완대체의학 사용 실태조사 연구의 동향 분석 (Research Trend Analysis of the Prevalence of Complementary and Alternative Medicine in Korea)

  • 김슬기;이상훈;서현주;백승민;최선미
    • 대한한의학회지
    • /
    • 제33권1호
    • /
    • pp.24-41
    • /
    • 2012
  • Objectives: This study reviewed research trends concerning the prevalence of complementary and alternative medicine (CAM) use and to suggest future research directions appropriate to medical circumstances in Korea. Methods: We searched for surveys of CAM use in 8 databases including 6 Korean databases, Ovid MEDLINE, and the CINAHL electronic database. Three independent reviewers working in pairs screened titles and abstracts of articles for eligibility. Full text was retrieved in case of disagreement on the eligibility. The main analysis targets included survey researcher's affiliation, terminology used in the title, study subject, definition of CAM, classifications of CAM modalities, and the area assortment of CAM and traditional Korean medicine (TKM). Results: 92 articles were included for analysis. The major constituent of affiliation was doctors (53%). According to years, study subjects were diversified to a large range of diseases. Since 2003, terminology is absorbed to use CAM. But actually, the most commonly used definition in the research was comprehensive such as "not generally considered part of major medicine" (55.4%) and the most used classification of CAM was self-criteria (61.9%). As for area assortment of CAM and TKM, many therapies exist in a gray zone between CAM and TKM. Conclusions: Standardized definition and classification criteria about CAM fit to the Korean healthcare system have not yet developed. For traditional Korean medicine academia, more concern should be paid to establishing appropriate development of definitions and classification criteria.

뇌졸중 후 인지장애의 침 치료에 대한 임상적 연구 고찰 (A Study of Clinical Research Acupuncture Treatment on Post-stroke Cognitive Disorder)

  • 김삼룡;윤종민;문병순
    • 대한한방내과학회지
    • /
    • 제39권3호
    • /
    • pp.389-404
    • /
    • 2018
  • Objective: The aim of this study was to investigate acupuncture therapy for post-stroke cognitive disorder to suggest the methods of a study about acupuncture therapy. Methods: Several academic databases were used in this study, including National Digital Science Library (NDSL), National Assembly Library of Korea, Korean Traditional Knowledge Portal, Research Information Sharing Service (RISS), Korean studies Information Service System (KISS), Korean Medical Database (KMBASE), Korea Med, Oriental Medicine Advanced Searching Integrated System (OASIS), PubMed, MEDLINE with Full Text, and China National Knowledge Infrastructure (CNKI). Keywords used were "중풍", "뇌졸중", "인지장애", "침", "acupuncture", and "cognitive disorder". Results: Ultimately, 28 papers were investigated. that were mainly published in 2012 and 2016. Of these, More than two-thirds received a score of one or less on the Jadad scale. Acupuncture points such as GV20, GV24, PC6, EX-HN1, SP6, and GV26 were most frequently used. The treatment duration was mostly 30 minutes or less, and the treatment cycle was mostly for four weeks. Dilatational wave was generally used in pulse wave form, and amplitude of electricity was increased until patients were able to endure. G6805 was generally used in electric acupuncture apparatus. According to results of acupuncture treatment, assessments such as the MMSE (Mini Mental State Examination) and the Montreal Cognitive Function Assessment Scale (MoCA) showed statistically significant improvements in 28 studies. Conclusions: Future research is needed to standardize the treatment of acupuncture, and more diversified high quality papers should be published to help clarify the therapeutic effects of acupuncture and the mechanisms of cognitive disorder post-stroke.

Laparoscopic Versus Open Surgery for Rectal Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • Zhang, Feng-Wa;Zhou, Zhao-Yu;Wang, Hai-Lin;Zhang, Jv-Xia;Di, Bao-Shan;Huang, Wen-Hui;Yang, Ke-Hu
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권22호
    • /
    • pp.9985-9996
    • /
    • 2014
  • Background and Aim: Laparoscopic and open rectum surgery for rectal cancer remains controversial. This systematic review compared the short-term and long-term efficiency and complications associated with laparoscopic and open resection for rectal cancer. Materials and Methods: We searched PubMed, Embase, Cochrane Library, ISI Web of Knowledge and the China Biology Medicine Database to identify potential randomized controlled trials from their inception to March 31, 2014 without language restriction. Additional articles were identified from searching bibliographies of retrieved articles. Two reviewers independently assessed the full-text articles according to the pre-specified inclusion and exclusion criteria as well as the methodological quality of included trials. The meta-analysis was performed using RevMan 5.2. Results: A total of 16 randomized controlled trials involving 3,045 participants (laparoscopic group, 1,804 cases; open group, 1,241 cases) were reviewed. Laparoscopic surgery was associated with significantly lower intraoperative blood loss, earlier return of bowel movement and reduced length of hospital stay as compared to open surgery, although with increased operative time. It also showed an obvious advantage for minimizing late complications of adhesion-related bowel obstruction. Importantly, there were no significant differences in other postoperative complications, oncological clearance, 3-year and 5-year or 10 year recurrence and survival rates between two procedures. Conclusions: On the basis of this meta-analysis we conclude that laparoscopic surgery has advantages of earlier postoperative recovery, less blood loss and lower rates of adhesion-related bowel obstruction. In addition, oncological outcome is comparable after laparoscopic and open resection for rectal cancer.

홍삼의 약리와 독성 기전에 대한 고찰 (Review of Red Ginseng in terms of Mechanisms for Pharmacodynamics and Toxicity)

  • 박영철;임정대;김종봉;이선동
    • 대한한의학회지
    • /
    • 제33권3호
    • /
    • pp.200-230
    • /
    • 2012
  • Objectives: Ginseng, Panax ginseng C. A., white ginseng, has been used for thousands of years in Traditional Korean Medicine. Red ginseng can be made by a steaming process of white ginseng changing a variety of ginsenosides and ingredients such as dencichine. This article reviews red ginseng for mechanisms for pharmacodynamics and toxicity based on the content of ginseng's active ingredients, ginsenoside changed by steaming. Methods: The following electronic databases were searched: PubMed, Science Direct and Chinese Scientific Journals full text database (CQVIP), and KSI (Korean Studies Information) from their respective inceptions to June 2012. Results: Compared with unsteamed ginseng, the content of ginsenosides Rg2, Rg3, Rg5, Rh1, Rh2 and Rk1 called red ginseng-specific ginsenosides increased after the steaming process. Different ginsenosides have shown a wide variety of effects such as lowering or raising blood sugar and blood pressure or stimulating or sedating the nervous system. Especially, the levels of Rg2, Rg3, Rg5, Rh1, Rh2 and Rk1 were increased by the steaming process, showing a variety of pharmacodynamics in biological systems. Also, various processing methods such as puffing and fermentation have been developed in processing crude ginseng or red ginseng, affecting the content of ginseng's ingredients. The safety issue could be the most critical, specifically, on changed ginseng's ingredients such as dencichine. The level of dencichine was significantly reduced in red ginseng by the steaming process. In addition, the possible toxicity for red ginseng was affected by cytochrome P450, a herbal-drug interaction. Conclusions: The variety of pharmacological and toxicological properties should be changed by steaming process of Panax ginseng C. A., white ginseng. Even if it is not sure whether the steaming process of white ginseng would be better pharmacologically, it is sure that steaming reduces the level of dencichine causing a lower toxicity to the nervous system.

언어학적 분석기법에 의한 신문기사 자동색인시스팀 설계에 관한 연구 (A Study of automatic indexing based on the linguistic analysis for newspaper articles)

  • 서경주;사공철
    • 정보관리학회지
    • /
    • 제8권1호
    • /
    • pp.78-99
    • /
    • 1991
  • 본 연구는 전자신문인 한경 KETEL의 기사 전문을 대상으로 키워드를 자동 추출하는 자동색인 시스팀을 구축한 것으로서 한글의 형태적 특성을 이용한 언어학적 분석기법을 적용해서 키워드 화일을 생성하는 법을 제시하였으며, 불용어리스트 조사표 용언인식표의 작성법을 상세히 기술했다. 본 연구에서 얻어진 결론은 다음과 같다. 첫째, 형태소 분석을 통한 자동색인 기법으로 만족할 만한 키워드를 추출할 수 있었다. 둘째, 아직까지는 컴퓨터에 의한 한글의 구문분석과 의미분석이 완전하지 못하므로 자동색인으로 추출된 색인어를 색인자가 조절함으로써 색인의 성능을 향상시킬 수 있었다. 셋째, 이 시스팀에서 만들어진 약 20,000어 정도의 키워드 화일은 향후 디소러스 작성에 기본 자료로 사용할 수 있다. 넷째, 본 시스팀에서는 역순사전을 활용해 조사표와 용언인식표 작성법을 제시하였는데, 이는 여러 자동색인 시스팀 설계에 적용될 수 있을 것이다.

  • PDF

XSTAR: XML 질의의 SQL 변환 알고리즘 (XSTAR: XQuery to SQL Translation Algorithms on RDBMS)

  • 홍동권;정민경
    • 한국지능시스템학회논문지
    • /
    • 제17권3호
    • /
    • pp.430-433
    • /
    • 2007
  • XML이 다양한 분야에 널지 이용되면서 대용량의 XML을 효과적으로 관리하는 여러 가지 방법들이 연구되고 있다. 특히 지금가지 상업적, 기술적으로 성공적인 데이터 모델인 관계형 데이터베이스를 기반으로 한 여러 가지 방법들이 연구되고 있다. 본 논문은 관계형 DBMS를 사용하여 XML 질의어인 XQuery를 SQL로 변환하는 알고리즘인 XSTAR(XQuery to SQL Translation Algorithms on RDBMS)를 설계 및 구현한다. 본 연구의 XSTAR 알고리즘은 기본적인 XPath 뿐만 아니라 XQuery FLWOR 표현식, XQuery함수, 그리고 전문 검색(Fulltext 검색[8])과 관련된 몇몇 특수한 기능을 효율적으로 지원할 수 있으며, 질의의 결과 값을 XML 형태로 재생성하여 사용자에게 반환한다. 본 논문에서 제안하는 XSTAR 알고리즘은 현재 웹 상에서 공개적으로 시범 운용되고 있는 XML 문서의 관리 및 질의 처리 시스템인 XPERT(XML Query Processing Engine using Relational Technologies, http://dblab.kmu.ac.kr/project.jsp")의 질의 처리 엔진으로 사용되고 있다.

Effectiveness of miniscrew assisted rapid palatal expansion using cone beam computed tomography: A systematic review and meta-analysis

  • Siddhisaributr, Patchaya;Khlongwanitchakul, Kornkanok;Anuwongnukroh, Niwat;Manopatanakul, Somchai;Viwattanatipa, Nita
    • 대한치과교정학회지
    • /
    • 제52권3호
    • /
    • pp.182-200
    • /
    • 2022
  • Objective: This study aims to examine the effectiveness of miniscrew assisted rapid palatal expansion (MARPE) treatment in late adolescents and adult patients using cone-beam computed tomography (CBCT). Methods: Literature search was conducted in five electronic databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) based on the PICOS keyword design focusing on MARPE. Out of the 18 CBCT screened outcomes, only nine parameters were sufficient for the quantitative meta-analysis. The parameters were classified into three main groups: 1) skeletal changes, 2) alveolar change, and 3) dental changes. Heterogeneity test, estimation of pooled means, publication bias, sensitivity analysis and risk of bias assessment were also performed. Results: Upon database searching, only 14 full-text articles were qualified from the 364 obtained results. Heterogeneity test indicated the use of the random-effects model. The pooled mean estimate were as follows: 1) Skeletal expansion: zygomatic width, 2.39 mm; nasal width, 2.68 mm; jugular width, 3.12 mm; and midpalatal suture at the posterior nasal spine and anterior nasal spine, 3.34 mm and 4.56 mm, respectively; 2) Alveolar molar width expansion, 4.80 mm; and 3) Dental expansion: inter-canine width, 3.96 mm; inter-premolar width, 4.99 mm and inter-molar width, 5.99 mm. The percentage of expansion demonstrated a skeletal expansion (PNS) of 55.76%, alveolar molar width expansion of 24.37% and dental expansion of 19.87%. Conclusions: In the coronal view, the skeletal and dental expansion created by MARPE was of the pyramidal pattern. MARPE could successfully expand the constricted maxilla in late adolescents and adult patients.

R과 LDA 기법을 활용한 클라우드 컴퓨팅 동향에 관한 연구: 해외 연구 동향을 중심으로 (Study on Tendency of Cloud Computing Using R and LDA Technique : Focusing on Tendency of Overseas Studies)

  • 강태구
    • 한국융합학회논문지
    • /
    • 제13권5호
    • /
    • pp.261-266
    • /
    • 2022
  • 4차 산업혁명에서 비롯된 디지털 시대의 본격화와 COVID-19의 영향으로 기업뿐만 아니라 다양한 분야에서 변화가 일어나고 있는 상황이다. 디지털 서비스의 급격한 증가로 인해 클라우드 시장 또한 성장 가속화로 빠르게 변화하는 디지털 환경에서 중요성이 더욱더 강조되고 있는 실정이다. 이에 관련 산업뿐만 아니라 다양한 분야에서 클라우드는 지속적인 성장과 생존전략을 위한 대표적인 전략 중 하나라고 할 수 있다. 클라우드 관련 연구는 다양하게 진행되고 있지만 연구 동향은 미흡한 실정이다. 이에 본 논문은 R과 LDA 기법을 활용한 외국 학술 데이터 베이스인 SCOPUS를 활용하여 클라우드 컴퓨팅의 연구 동향을 분석하였다. 분석 결과 클라우드 컴퓨팅 관련 높은 관심으로 수많은 연구가 진행되고 있는 것으로 나타났고, 키워드 분석 결과 클라우드 컴퓨팅이 가장 많이 도출되었다. 클라우드 컴퓨팅 주제 외에도 클라우드, 클라우드와 컴퓨팅, 데이터, 컴퓨팅의 다양한 주요 키워드들이 도출되었다. 본 연구 결과는 클라우드 컴퓨팅 동향 파악을 위한 실무적인 측면에서 관련 산업 활성화에 밑거름을 제공할 수 있는 기초자료로 활용될 것으로 기대된다.