• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.219-227
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• 2019

The purpose of this study is to investigate the relationship between self - integration and frontal cognitive function in the welfare center users. The data were collected on January 18-30, 2018. 120 people in the M city, has participated in more than 65 years older. data were analyzed using frequency, mean and standard deviation, t-test, ANOVAs, and Pearson's correlation coefficient and multiple regression analysis. The results of this study showed that current satisfaction of welfare center users is statistically different from 'attitude toward life', 'acceptance of lifetime', 'satisfaction of present life' of ego integrity. Self - integration sense showed 28.3% explanatory power in current life. Effect of prefrontal cognitive function in accordance with the partner showed a 16.1% explanatory power This study suggests the necessity of policy and program development for the elderly community life to improve self - integration and frontal cognitive function in old age.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.3
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• pp.192-200
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• 2008

To evaluate the hemodynamic changes and the predictive factors of the clinical outcome in pediatric patients with moyamoya disease, we analyzed pre/post basal/acetazolamide stress brain perfusion SPECT with automated volume of interest (VOIs) method. Methods: Total fifty six (M:F = 33:24, age $6.7{\pm}3.2$ years) pediatric patients with moyamoya disease, who underwent basal/acetazolamide stress brain perfusion SPECT within 6 before and after revascularization surgery (encephalo-duro-arterio-synangiosis (EDAS) with frontal encephalo-galeo-synangiosis (EGS) and EDAS only followed on contralateral hemisphere), and followed-up more than 6 months after post-operative SPECT, were included. A mean follow-up period after post-operative SPECT was $33{\pm}21$ months. Each patient's SPECT image was spatially normalized to Korean template with the SPM2. For the regional count normalization, the count of pons was used as a reference region. The basal/acetazolamide-stressed cerebral blood flow (CBF), the cerebral vascular reserve index (CVRI), and the extent of area with significantly decreased basal/acetazolamide- stressed rCBF than age-matched normal control were evaluated on both medial frontal, frontal, parietal, occipital lobes, and whole brain in each patient's images. The post-operative clinical outcome was assigned as good, poor according to the presence of transient ischemic attacks and/or fixed neurological deficits by pediatric neurosurgeon. Results: In a paired t-test, basal/acetazolamide-stressed rCBF and the CVRI were significantly improved after revascularization (p<0.05). The significant difference in the pre-operative basal/acetazolamide-stressed rCBF and the CVRI between the hemispheres where EDAS with frontal EGS was performed and their contralateral counterparts where EDAS only was done disappeared after operation (p<0.05). In an independent student t-test, the pre-operative basal rCBF in the medial frontal gyrus, the post-operative CVRI in the frontal lobe and the parietal lobe of the hemispheres with EDAS and frontal EGS, the post-operative CVRI, and ${\Delta}CVRI$ showed a significant difference between patients with a good and poor clinical outcome (p<0.05). In a multivariate logistic regression analysis, the ${\Delta}CVRI$ and the post-operative CVRI of medial frontal gyrus on the hemispheres where EDAS with frontal EGS was performed were the significant predictive factors for the clinical outcome (p =0.002, p =0.015), Conclusion: With probabilistic map, we could objectively evaluate pre/post-operative hemodynamic changes of pediatric patients with moyamoya disease. Specifically the post-operative CVRI and the post-operative CVRI of medial frontal gyrus where EDAS with frontal EGS was done were the significant predictive factors for further clinical outcomes.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.30 no.6
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• pp.546-553
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• 2008

Purpose: The purpose of this study was to estimate validity of posterior anterior cephalometric and 3D-CT for orbital canting analysis. Materials and methods: Three trained observers classified two patients group using standardized frontal photographs of facial asymmetry patients. Group A consisted of patients with facial asymmetry and orbital canting(n=19), and group B consisted of patients with only facial asymmetry(n=43). Orbital canting was measured with line of bilateral inferior orbitale. Orbital canting measurement was done with posterior anterior cephalometric and 3D-CT. Each horizontal reference line was established by bilateral GWSO(cephalometric), FZS(3D-CT). Maxillary canting and mandibular deviation angle were also measured and analyzed with orbital canting. Results: The mean orbital canting was $3.03{\pm}1.00^{\circ}$ in Group A and $1.11{\pm}0.76^{\circ}$ in Group B in frontal photograph. The mean orbital canting was $1.20{\pm}0.74^{\circ}$ in group A and $1.22{\pm}0.65^{\circ}$ in group B by cephalometric analysis(p>0.05). In 3D-CT, orbital canting was almost paralleled with horizontal reference line. The orbital canting, maxillay canting and mandibular deviation between two groups showed no significant differences except madibular deviation in 3D-CT. Conclusion: Common analysis of posterior anterior cephalometric and 3D-CT is not valide method to evaluate orbital canting for facial asymmetry patients with orbital canting.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.4
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• pp.1552-1558
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• 2011

In this paper, the automotive beam using aluminium foam is designed and the impact analysis is carried out. The analysis model is the beam of actual size with B- type section structure. At the frontal crash of low speed, ANSYS AUTODYN is used by predicting the behavior of deformation and its internal energy. By the use of 7075-T6 aluminum alloy, the weight is reduced as much as 55% than steel. The deformation at the bumper foam of aluminum is similar with that of steel and the impact energy reduction at aluminum is more than steel. The foam filled with aluminum as much as 50 % has more impact energy absorption than the completely filled aluminum foam.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.555-564
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• 2006

The aim of this paper is to contribute to the efficient design of traffic light poles involved in vehicle frontal collisions by developing a computer-based, finite-element model capable of capturing the impact characteristics. This is achieved by using the available non-linear dynamic analysis software "LS-DYNA3D", which can accurately predict the dynamic response of both the vehicle and the traffic light pole. The fiber reinforced polymer(FRP) as a new pole's material is proposed in this paper to increase energy absorption capabilities in the case of a traffic pole involved in a vehicle head-on collision. Numerical analyses are conducted to evaluate the effects of key parameters on the response of the pole embedded in soil when impacted by vehicles, including: soil type(clay and sand) and pole material type(FRP and steel). It is demonstrated from the numerical analysis that the FRP pole-soil system has favorable advantages over steel poles, where the FRP pole absorbed vehicle impact energy in a smoother behavior, which leads to smoother acceleration pulse and less deformation of the vehicle than those encountered with steel poles. Also, it was observed that clayey soil brings a slightly more resistance than sandy soil which helps reducing pole movement at ground level. Finally, FRP pole system provides more energy absorbing leading to protection during minor impacts and under service loading, and remain flexible enough to avoid influencing vehicle occupants, thus reducing fatalities and injuries resulting from the crash.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.11
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• pp.1179-1185
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• 2013

In this study, the design optimization of the automotive side member is performed to maximize the crash energy absorption efficiency per unit weight. Design parameters which seriously influence on the frontal crash performance are selected through the sensitivity analysis using the Plackett-Burman design method. And also the design variables, which are determined from the sensitivity analysis, are optimized by two methods. One is conventional approximate optimization method which uses the statistical design of experiments (DOE) and response surface method (RSM). The other is a methodology derived from previous work by the authors, which is called sequential design of experiments (SDOE), to reduce a trial and error procedure and to find an appropriate condition for using micro-genetic algorithm. The proposed optimization technique shows that the automotive side member structure can be designed considering the frontal crash performance.

• Bulletin of the Korean Chemical Society
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• v.26 no.1
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• pp.136-138
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• 2005

High-performance frontal analysis (HPFA) was used for the determination of the binding constant of Sibuprofen to human serum albumin (HSA). This experiment was based on an Inertsil 100 Diol 5 column and sodium phosphate buffer (pH 7.4 and ionic strength of 0.17) as the mobile phase. The mixture of S-ibuprofen and HSA (70 $\mu$M) solution were directly injected into the HPFA column. An injection volume of 200 $\mu$L and a “estricted injection”method were applied to ensure the drug to be eluted as a zonal peak with a plateau. The unbound drug concentration was calculated from the peak height of the zonal peak. Scatchard analysis was used for evaluation of the binding constant (K) and binding affinity (nK) of S-ibuprofen to HSA, and the results were K = 2.833 ${\times}$ 10$^4$ [L mol$^{-1}$], nK = 4.935 ${\times}$ 10$^4$ [L mol$^{-1}$], respectively.

• Dementia and Neurocognitive Disorders
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• v.17 no.3
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• pp.110-119
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• 2018

Background and Purpose: To analyze $^{18}F-THK5351$ positron emission tomography (PET) scans of patients with clinically diagnosed nonfluent/agrammatic variant primary progressive aphasia (navPPA). Methods: Thirty-one participants, including those with Alzheimer's disease (AD, n=13), navPPA (n=3), and those with normal control (NC, n=15) who completed 3 Tesla magnetic resonance imaging, $^{18}F-THK5351$ PET scans, and detailed neuropsychological tests, were included. Voxel-based and region of interest (ROI)-based analyses were performed to evaluate retention of $^{18}F-THK5351$ in navPPA patients. Results: In ROI-based analysis, patients with navPPA had higher levels of THK retention in the Broca's area, bilateral inferior frontal lobes, bilateral precentral gyri, and bilateral basal ganglia. Patients with navPPA showed higher levels of THK retention in bilateral frontal lobes (mainly left side) compared than NC in voxel-wise analysis. Conclusions: In our study, THK retention in navPPA patients was mainly distributed at the frontal region which was well correlated with functional-radiological distribution of navPPA. Our results suggest that tau PET imaging could be a supportive tool for diagnosis of navPPA in combination with a clinical history.

• Journal of Auto-vehicle Safety Association
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• v.10 no.3
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• pp.7-12
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• 2018

The Korean New Car Assessment Program (KNCAP) is a program to evaluate the safety of automobiles. In the safety assessment method, there are frontal collision, partial frontal collision, side collision, pillar collision, and left stability in the collision safety category. Among them, Korean in-depth analysis data shows that there are a lot of side collision accidents and it is necessary to protect them. This study will analyze the side collision accident that occurred in actual traffic accident based on Korea In-Depth Accident Study (KIDAS) and investigate the effect of center airbag on passenger in under side collision. In addition, with simulated side collision scenarios in the various side impact directions, it was investigated how the center airbag affects the driver and passenger in terms of kinematic and injury levels.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.12
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• pp.129-136
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• 2000

In the frontal collision the spot welded hat-shaped section side member is the fundamental structure for automobiles and has a great amount of absorbing capacity. For this reason LS-DYNA3D has been used for analyzing impact collapse characteristics on hat shaped section member with respect to the valuables; thickness, width ratio and spot weld potch on impact load(7.19m/sec, 1034J). By comparing the results from simulation and the experimental results, the utilization of simulation has been certified.