• 아동학회지
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• 제21권4호
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• pp.143-158
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• 2000

This study examined whether children's peer representations are associated with peer acceptance and whether attributions and goals are related to representations about behavioral responses in ambiguous provocation and conflict situations. The subjects were 119 5th-grade children responded to 4 hypothetical situations. Results indicated that children's positive representations about peer conduct in ambiguous provocations were related to their higher level of peer acceptance, and positive representations about a friend in conflict situations were associated with their perceived positive qualities of friendship. Children's positive attribution and relational goal orientation were associated with relational behavioral responses. Gender differences were found for some goals and behavioral responses, with girls displaying a more relational goal and behavioral response orientation than boys.

• 아동학회지
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• 제23권4호
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• pp.171-183
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• 2002

This study examined the applicability of creative drama to a social competence program for poorly accepted(socially at-risk) elementary school children. The subjects were 40 $2^{nd}$(n=20) and $5^{th}$(n=20) grade children. The experimental group(n=20) participated in a social competence program that included 18 sessions of the creative drama activities during winter vacation. The Peer Rating Scale, the Peer Competence Scale, and the Quality of Friendship Scale were administered as pre- and post-test. Covariance analyses showed no differences between experimental and control groups on peer competence and quality of friendship, but the children who participated in the program showed some differences in total scores and sub-areas on quality of friendship by grade and level of peer pre-acceptance.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6293-6299
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• 2013

Background: A number of clinicopathologic factors have been found to be associated with pathological lymph node metastasis (pLNM) in rectal cancer; however, most of them can only be identified by expensive high resolution imaging or obtained after surgical treatment. Just like the Child-Turcotte-Pugh (CTP) and the model for end-stage liver disease (MELD) scores which have been widely used in clinical practice, our study was designed to assess the pre-operative factors which could be obtained easily to predict intra-operative pLNM in rectal cancer. Methods: A cohort of 469 patients who were treated at our hospital in the period from January 2003 to June 2011, and with a pathologically hospital discharge diagnosis of rectal cancer, were included. Clinical, laboratory and pathologic parameters were analyzed. A multivariate unconditional logistic regression model, areas under the curve (AUC), the Kaplan-Meier method (log-rank test) and the Cox regression model were used. Results: Of the 469 patients, 231 were diagnosed with pLNM (49.3%). Four variables were associated with pLNM by multivariate logistic analysis, age<60 yr (OR=1.819; 95% CI, 1.231-2.687; P=0.003), presence of abdominal pain or discomfort (OR=1.637; 95% CI, 1.052-2.547; P=0.029), absence of allergic history (OR=1.879; 95% CI, 1.041-3.392; P=0.036), and direct $bilirubin{\geq}2.60{\mu}mol/L$ (OR=1.540; 95% CI, 1.054-2.250; P=0.026). The combination of all 4 variables had the highest sensitivity (98.7%) for diagnostic performance. In addition, age<60 yr and direct $bilirubin{\geq}2.60{\mu}mol/L$ were found to be associated with prognosis. Conclusion: Age, abdominal pain or discomfort, allergic history and direct bilirubin were associated with pLNM, which may be helpful for preoperative selection.

• 정보교육학회논문지
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• 제20권5호
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• pp.499-506
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• 2016

다문화가정 학생은 한국어 의사소통능력 미비, 학습부진, 심리적 불안 등 다양한 문제를 가지고 있다. 이러한 문제를 해결하기 위해 다문화가정 초등학생을 대상으로 학습태도, 상호작용, 사회성 향상을 위한 소프트웨어교육 프로그램을 설계하여 개발하였다. 소프트웨어교육 프로그램은 ADDIE모형의 주요 단계에 따라 개발하였으며 놀이-요구 분석-디자인-구현-공유 및 토론단계의 교수학습모형을 개발하였다. 소프트웨어교육 프로그램의 효과성을 분석하기 위해 다문화가정 4, 5, 6학년 초등학생 15명을 실험집단으로 선정하여 프로그램을 적용하였고 사전 사후 검사 결과를 통해 교육적 효과를 분석하였다. 분석 결과, 본 연구에서 개발한 소프트웨어교육 프로그램이 다문화가정 학생의 학습태도, 교우관계, 사회성 및 프로그래밍 흥미도에서 유의미한 영향을 미치는 것으로 나타났다.

• 한국학교ㆍ지역보건교육학회지
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• 제16권3호
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• pp.65-78
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• 2015

Objectives: The purpose of this study was to investigate self esteem and stress of students at their universities for the development of a program related to school life and guidance. Methods: The survey were carried out in 5 universities located in Gyounggi Do, Gyungbuk Do, Busan city and Daegu city from 2014. October 1. to November 30. Out of a total of 500 Questionnaires answered by 500 students, 489 Questionnaires, were analyzed with SPSS version 12.0. Results: The total mean of the self esteem point of college student's school living was $3.41{\pm}0.44$ points. The total mean of the general stress point of college students was $2.67{\pm}0.52$ points. Affecting factors of the self-esteem of subjects(multiple regression analysis) were important things of school living(p<0.05), human and friendship(p<0.05), protector's job(p<0.001), home economic states(p<0.001), and friendship(p<0.001). Based on multiple regression analysis, affecting factors of the stress of subjects were important things of school living(p<0.05), human and friendship(p<0.05), religion(p<0.001), protector's job(p<0.001), friendship(p<0.001), and arbeit job(p<0.05). Conclusions: The results of this study help to provide a basis for development of a strategy to improve the self-esteem and solve problems of stress for university students. Also relevant programs should be developed and provided by related authorities and universities.

• Journal of Gastric Cancer
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• 제20권1호
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• pp.95-105
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• 2020

Purpose: Gastric cancer is a highly metastatic malignant tumor, often characterized by chemoresistance and high mortality. In the present study, we aimed to investigate the role of B-cell lymphoma 3 (Bcl-3) protein on cell migration and chemosensitivity of gastric cancer. Materials and Methods: The gastric cancer cell lines, AGS and NCI-N87, were used for the in vitro studies and the in vivo studies were performed using BALB/c nude mice. Western blotting, wound healing assay, Cell Counting Kit-8 assay, immunohistochemistry, and terminal deoxynucleotidyl transferase dUTP nick end labeling assay were used to evaluate the role of Bcl-3 in gastric cancer. Results: We found that the protein expression of hypoxia (HYP)-inducible factor-1α and Bcl-3 were markedly upregulated under hypoxic conditions in both AGS and NCI-N87 cells in a time-dependent manner. Interestingly, small interfering RNA-mediated knockdown of Bcl-3 expression affected the migration and chemosensitivity of the gastric cancer cells. AGS and NCI-N87 cells transfected with si-RNA-Bcl-3 (si-Bcl-3) showed significantly reduced migratory ability and increased chemosensitivity to oxaliplatin, 5-fluorouracil, and irinotecan. In addition, si-Bcl-3 restored the autophagy induced by HYP. Further, the protective role of si-Bcl-3 on the gastric cancer cells could be reversed by the autophagy inducer, rapamycin. Importantly, the in vivo xenograft tumor experiments showed similar results. Conclusions: Our present study reveals that Bcl-3 knockdown inhibits cell migration and chemoresistance of gastric cancer cells through restoring HYP-induced autophagy.

• Asian Pacific Journal of Cancer Prevention
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• 제16권12호
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• pp.4839-4841
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• 2015

We conducted a retrospectively reviewed of the literature published of patients underwent fertility-preserving treatments for cervical, endometrial and ovarian cancers using the WANFANG database in Chinese. A majority were retrospective studies and case reports. With cervical cancer, radical trachelectomy(RT) in combination with pelvic lymphadenectomy could preserve the fertility of patients with early stage IA1-IB1 cancers, Tumor size ${\leq}2cm$ should be emphasized as the indication of RT in considering of the higher recurrent rate in patients with tumor size >2cm. For endometrial cancers, there is much experience on it. Given accurate pretreatment assessment, hormonal therapy is feasible management option to preserve fertility in young patients with early stage lesions that limited to the endometrium and well differentiated. High dose progestin have been applied, oral medroxyprogesterone acetate (MPA), 250-500mg/day, megestrol acetate 160-480mg/day. Other therapies that have been used in a limited number of cases include GnRH analog, intrauterine devices (IUDS) containing progestogen, usually combination of these therapies. All patients should be followed up by ultrasound and/or MRI evaluation, and endometrial curettage at intervals of 3 months. With ovarian cancer, in China, fertilitypreserving surgery in patients with stage IA (grade G1) of epithelial ovarian tumor and patients with germ cell tumor and borderline ovarian tumor have been successfully performed.

• 대한한의학회지
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• 제31권5호
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• pp.33-40
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• 2010

Objectives: The aim of this study was to investigate the current educational environment of Oriental medicine and to develop a future-oriented curriculum for traditional Korean medicine in Uzbekistan. The questionnaire used in this research was based on the current curriculum. Methods: This study was carried out by distributing questionnaires to 120 students (5th year in Tashkent medical academy in Uzbekistan) in order to examine the coursed's efficacy for the attainment of oriental medical knowledge. Results: 1. Among the respondents, 69.6% of them have already studied oriental medicine. 2. The respondents felt that the class in Oriental medicine was effective (88.3%). Moreover, they felt that understanding traditional Korean medicine was also beneficial (81.6%). However, 52.5% of them have responded that the class seemed difficult. 3. Among Uzbeki medical students, 64.9% of them have shown interest in acupuncture and moxibustion, 38.4% in traditional Korean herbology and pharmacognosy. 4. We also found that 63.8% of them have desired to have more specific studies in traditional Korean medicine. Conclusion: According to our results, developing adequate textbooks, teaching methods, and qualities of instructors should be considered as alternatives for the successful generalization of traditional Korean medicine in Uzbekistan.

• 대한영양사협회학술지
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• 제2권1호
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• pp.49-61
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• 1996

For the purpose of disclosing the relationship between job characteristics and satisfaction and organizational commitment for foodservice employees, questionnaire survey was carried out on 427 subjects of 14 general hospitals in Seoul, Korea. Questionnaire items consisted of general characteristics, organizational commitment, job satisfaction and characteristics. Data were analyzed by ANOVA, Duncan's multiple range test and Pearson correlation using SPSS PC package. The results were as follows 1. Mean score of value commitment and commitment to stay were 3.57 and 3.67. 2. There were significant differences between value commitment and age, marital status department, period and management, and between commitment to stay and experience and management. 3. Mean score of job satisfaction was the highest in co-workers(3.37) and work itself (3.37) and followed by in supervision(3.25), wage(2.43) and promotion(2.01). There were significant differences between job satisfaction for work itself and age, educational status and job department and management, between job satisfaction for wage and position, department, period and management, between job satisfaction for supervision and age, educational status and department, between job satisfaction for promotion and age, marital status, position, period, and management, between job satisfaction for co-workers and sex and educational status. 4. Mean score of job characteristics was the highest in dealing with others(4.13) and followed by in feedback(3.51), autonomy(3.29), task identify(3.07), variety(2.71) and friendship(2.47). 5. Job satisfaction for work itself, supervision and co-workers were significantly increased with increasing value commitment. Job satisfaction for work itself, supervision were significantly increased with increasing commitment to stay. Job satisfaction for promotion had negative correlation with organizational commitment in all job position. 6. Value commitment had significantly positive correlations with variety, autonomy, identity, feedback and dealing with others, and significantly negative correlation with friendship. Commitment to stay had significantly positive correlations with dealing with others, and significantly negative correlations with friendship. In all job position organizational commitment had significantly negative correlations with friendship.

• 한국가정과교육학회지
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• 제22권1호
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• pp.21-32
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• 2010

본 연구는 중학생을 대상으로 생별에 따른 자아존중감의 차이를 살펴보고, 가족요인과 또래요인이 청소년의 자아존중감에 어떠한 영향을 미치는지 파악하는 것을 목적으로 하였다. 이러한 연구목적을 위해 자아존중감, 부모와의 관계, 부모 감독, 부부갈등, 친구관계의 질, 또래괴롭힘의 척도를 구성하여, 경기도 부천 시내 5개의 중학교에서 2학년 학생 563 명을 대상으로 설문조사를 실시하였으며, 최종 분석에 532부의 자료를 사용하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 챙소년의 자아존중감은 높은 편이며, 성별에 따라 차이가 없었다. 둘째, 청소년의 자아존중감에 미치는 기족요인과 또래요인의 상대적 영향력을 살펴보면, 남자 청소년의 자아존중감에는 또래괴롭힘, 부모와의 관계, 친구관계의 질이 영향을 미치는 것으로 나타났고 여자, 청소년의 자아존중감에는 부모와의 관계, 친구관계의 질, 또래괴롭힘이 영향을 미치는 것으로 나타났다.