• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.3
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• pp.278-283
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• 2006

Styela clava was processed by four different kinds of method including FR (fresh S. clava), H1 (heat treated S. clava at $110^{\circ}C$ for 15 min) H2 (heat treated S. clava at $120^{\circ}C$ for 5 min), and FD (freeze dried S. clava). Each S. clava sample was treated with methanol, ethanol, acetone, and water, then antioxidant and anticancer activities of the extracts were evaluated. In extracts from non-dried S. clava (FR, H1, and H2), total extract yield decreased with increasing treated temperature. The extraction yield was in the order of ethanol>methanol>water>acetone among treated solvents. In case of dried S. clava (FR), the extraction yield was lower than non-dried samples, and was in the order of methanol>ethanol>water>acetone. The radical scavenging activity (RSA) of non-dried S. clava (FR, H1, and H2) was in the order of acetone>ethanol>methanol and heat treatment also decreased RSA. RSA of FD was the highest in ethanol extract, while acetone and water extracts did not show RSA. When antioxidant activity was determined by reducing power (RD), methanol extract of FR showed the highest values and heat treatment decreased RD, too. RD of FD was in the order of methanol>ethanol>water>acetone. The acetone extracts from FD showed significant anticancer activity against human colon cancer cell line HT-29. These results indicated that extraction yield and properties of extracts from S. clava were dependent on processing temperature, solvent and/or physicochemical state. The appropriate extraction process should provide some valuable bioactive materials from S. clava.

• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.1
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• pp.118-122
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• 2016

When a geometric size of moonpool and an inflow velocity are determined based on the similarity of Froude number, Reynolds number is depending on the scale ratio of moonpool geometry. It means that different characteristics of flow fluctuations in moonpool can be observed depending on the scale ratio of moonpool even though Froude number is the same. In the present study two dimensional numerical simulations were performed to investigate the influence of scale ratios on the flow characteristics inside the moonpool. The inflow velocity at several scale ratios was determined to keep Froude number constant. A periodic response was observed in a small size of moonpool while a large moonpool showed complicated fluctuations with various amplitudes and frequencies, which made it difficult to distinguish the statistical steady-state response from the temporal responses in the case of large moonpool. The similarity of Froude number gave rise to a spectral characteristic which was inversely proportional to the square root of scale ratios ($f_{0.5}{\approx}{\sqrt{2}}f_1{\approx}2f_{2.0}$) but a low frequent occurrence of strong vortex ($f_{2.0}=0.07$)which is observed inside the large moonpool was characterized depending on scale ratios.

• The Korean Journal of Mycology
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• v.36 no.1
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• pp.66-74
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• 2008

Tremella aurantialba, one of edible and medicinal mushrooms belonging to Tremellaceae of Basidiomycota, has been known to have outstanding curing effects on coughing, tracheitis and hypertension of humans and antitumor activity on the sarcoma 180 and Erhrlich carcinoma of mice. Neutral saline soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr. NaCl, Fr. HW and Fr. MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests showed that all crude polysaccharides extracted from the fruiting body were not cytotoxic against cancer cell lines such as RAW 309 CR.1 and Sarcoma 180 at the concentration of $2000\;{\mu}g/ml$. Intraperitoneal injection with crude polysaccharides exhibited life prolongation effect of $11.1{\sim}66.7%$ in mice inoculated with Sarcoma 180. Fr. MeOH improved the immunopotentiation activity of B lymphocyte by increasing the alkaline phosphatase activity by 1.16 folds at the concentration of $200\;{\mu}g/ml$. In case of Fr. HW, the numbers of peritoneal exudate cells and circulating leukocytes were increased by 1.42 and 2.87 folds, respectively.

• The Korean Journal of Mycology
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• v.36 no.1
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• pp.84-92
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• 2008

Russula rosacea, one of edible and medicinal mushroom belonging Agaricales of Basidiomycota, has been known to have good inhibitory effects on sarcoma 180 and Ehrlich carcinoma of mice. Neutral saline soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr. NaCl, Fr. HW and Fr. MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests, crude polysaccharides were not cytotoxic against cancer cell lines such as Sarcoma 180, HepG2, HT-29 and NIH3T3 at the concentration of $10{\sim}2000\;{\mu}g/ml$. Intraperitoneal injection with crude polysaccharides exhibited life prolongation effect of $21.4{\sim}45%$ in mice previously inoculated with Sarcoma 180. Fr. HW improved the immuno-potentiation activity of B lymphocyte by increasing the alkaline phosphatase activity by 6.8 fold compared with control at the concentration of $500\;{\mu}g/ml$. In case of Fr. NaCl, the numbers of peritoneal exudate cells and circulating leukocytes were increased by 6 and 2.6 folds at the concentration of 50 mg/kg, respectively. Therefore, the antitumor effect against mice Sarcoma 180 by Russula rosacea could be due to immunomodulating activity.

• The Korean Journal of Mycology
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• v.35 no.2
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• pp.101-108
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• 2007

Armillaria tabescens, one of edible and medicinal mushrooms belonging to Agaricales of Basidiomycota, has been known to have outstanding curative effects on chronic hepatitis and cholecystitis and inhibitory effects on the sarcoma 180 and Erhrlich carcinoma of mice. Neutral saline soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr, NaCl, Fr. HW and Fr, MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests showed that crude polysaccharides were not cytotoxic against cancer cell lines such as NIH3T3 and Sarcoma 180 at the concentration of $2000\;{\mu}g/ml$. Intraperitoneal injection with crude polysaccharides exhibited life prolongation effect of $28.8{\sim}46.5%$ in mice inoculated with Sarcoma 180, respectively. Fr. NaCl improved the immunopotentiation activity of B lymphocyte by increasing the alkaline phosphatase activity by $1.8{\sim}2.1$ folds, respectively. In case of Fr, NaCl, the numbers of peritoneal exudate cells and circulating leukocytes were increased by 9 and 1.9 folds, respectively.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.1373-1377
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• 2008

강우-유출에 의해 성층화된 저수지로 유입하는 하천수는 저수지 표층에 비해 낮은 수온과 높은 부유물질(SS) 농도를 가지므로 저수지 표층수보다 상대적으로 높은 밀도를 유지한다. 하천으로부터 유입한 밀도류는 유속에 의한 관성력이 두 수체의 밀도차에 의한 음의 부력보다 큰 구간까지는 저수지 표층을 따라 진행하지만, 두 힘이 같아지는 지점에서 밀도류는 더 이상 진행하지 못하고 저수지 수면 아래로 침강하며 이 과정에서 수체간의 많은 혼합이 일어난다. 따라서 홍수시 유입한 탁수의 침강점에 대한 정확한 예측은 수질관리를 위한 현장조사, 그리고 탁수거동 해석 및 최적관리대책 마련에 중요한 요소이다. 본 연구의 목적은 홍수시 대청호로 유입하는 하천 밀도류의 침강위치를 홍수규모별로 경험식과 수치모델을 통해 산정함으로써 두 방법 간의 장 단점을 비교하고, 탁수 현장조사와 최적관리를 위한 기초정보를 제공하는데 있다. 유입수의 모의조건은 그 동안 대청호에서 발생한 홍수 크기를 기준으로 9개의 등급으로 나누었으며, 저수지 성층조건은 여름철 탁수가 유입되기 전의 발달된 성층구조를 적용하였다. 유입수와 저수지 성층구조의 특성치는 밀도 Froude 수($Fr_i$)로 나타냈으며, $Fr_i$ 조건별로 침강점 위치를 저수지 단면을 삼각형태로 가정한 Hebbert et al.(1979) 경험식과 2차원 수치모델로 산정하여 그 결과를 비교하였다. 대청호로 유입한 탁수는 홍수규모에 따라 대정리 수역에서 회남수역 사이 구간에서 침강하였으며, $Fr_i$ 값이 클수록 침강점 수심이 깊어지는 경향을 보였다. 경험식으로 산정한 침강점 수심은 정상상태 조건을 가정하므로 홍수에 의한 수위변화를 고려하지 못하며, 실제의 불규칙한 하상표고를 일정한 하상경사로 가정하기 때문에 2차원 모델의 결과보다 과대산정하는 경향을 보였다. 따라서 홍수가 연속해서 발생하며 수위변화가 심한 국내 저수지 여건에서 하천 유입 밀도류의 거동을 보다 정확히 예측하기 위해서는 2차원 또는 3차원 수치모델을 적용하는 것이 타당할 것으로 판단된다.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.05a
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• pp.307-310
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• 2013

본 논문은 한국어-스페인어와 한국어-불어 간의 양방향 이국어 사전(Bi-directional bilingual lexicon)을 자동으로 구축하기 위한 새로운 방법을 제안한다. 일반적으로 한국어와 스페인어/불어 간의 병렬 말뭉치를 직접적으로 구축하기에는 어려움에 따르기 때문에, 영어를 중심언어로 하는 영어(EN)-한국어(KR)/스페인어(ES)/불어(FR) 병렬 말뭉치를 이용하여 문맥 벡터를 만들고 그들 간의 유사도를 계산하는 변형된 문맥 벡터 방법을 제안한다. 영어는 다른 언어와의 이국어 병렬 말뭉치가 비교적 많이 공개되어 있기 때문에 이 방법을 이용하면 비교적 쉽게 KR-ES와 KR-FR 양방향 이국어 사전을 구축할 수 있다. 본 논문에서 제안한 방법으로 실험해본 결과 최고 85%(ES${\rightarrow}$KR)의 정확도를 얻을 수 있었다.

• Clean Technology
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• v.17 no.1
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• pp.69-77
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• 2011

The intrinsic $CO_2$ separation and hydrogen production system is a novel concept using oxidation and reduction reactions of oxygen carrier for both $CO_2$ capture and high purity hydrogen production. The process consists of a fuel reactor (FR), a steam reactor (SR) and an air reactor (AR). The natural gas ($CH_4$) is oxidized to $CO_2$ and steam by the oxygen carrier in FR, whereas the steam is reduced to hydrogen by oxidation of the reduced oxygen carrier in SR. The oxygen carrier is fully oxidized by air in AR. In the present study, the chemical looping moving bed reactor having 200 L/h hydrogen production capacity is designed and the hydrodynamic properties were determined. Compared with other reactors, two moving bed reactors (FR, SR) were used to obtain high conversion and selectivity of the oxygen carrier. The desirable solid circulation rates are calculated to be in the range of $20{\sim}100kg/m^2s$ from the conceptual design. The solid circulation rate can be controlled by aeration in a loop-seal. To maintain the gas velocity in the moving beds (FR, SR) at the minimum fluidization velocity is found to be suitable for the stable operation. The solid holdup in moving beds decrease with increasing gas velocity and solid circulation rate.

• Polymer(Korea)
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• v.36 no.3
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• pp.295-301
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• 2012

Efficient stitching methods for the synthesis of Fr$\acute{e}$chet-type dendrimers with linear PEG units at a core were elaborated. The synthetic strategy involved an inexpensive 1,3-dipolar cycloaddition reaction between an alkyne and an azide in the presence of Cu(I) species which is known as the best example of click chemistry. The linear core building blocks, two diazido-PEG units, were chosen to serve as the azide functionalities for dendrimer growth via click reactions with the alkyne-dendrons. These two building blocks were employed together with the alkyne-functionalized Fr$\acute{e}$chet-type dendrons in a convergent strategy to synthesize two kinds of Fr$\acute{e}$chet-type dendrimers with different linear core units.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.05a
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• pp.348-353
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• 2006

Autonomous and intelligent resource model (AIR-model) defines a building-block of complex systems to pursue value creation by means of diverse resources, referred to as an AIR-unit, and presents a collaboration model with the AIR-units. An AIR-unit represents a piece of resources, such as machines, labor, raw materials, and other assets, considered individually by a complex system as means to accomplish given tasks. It is defined with its own service capability and a goal, and pursues achieving the goal by means of the capability. Moreover, an Air-unit is equipped with autonomy and intelligence, whereby it makes a decision on its course of action on its own initiative. Air-units collaborate on system operations with each other through goal-oriented negotiations. In this research, distinctive features of the AIR-model are addressed and described in detail. Principal components of the AIR-model are also designed via object-oriented modeling techniques. A prototype system based on the AIR-model is finally presented as an embodiment tool of a fractal manufacturing system (FrMS).