• 한국한의학연구원논문집
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• 제16권1호
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• pp.157-171
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• 2010

This study aimed to investigate the effect of four common types of Qigong position (standing, sitting, supine, and horse-riding position) on the autonomic nervous system. Thirty healthy subjects participated in this study once a week for four weeks. Electroencephalogram (EEG) was measured three times (before, during, and after the position) while the subject maintained one of four positions for ten minutes. There were significant changes in HRV components compared with EEG power spectra in the standing position. Especially, the ratio of low-to-high frequency (LF/HF) which represents a state of balance of autonomic nervous system was increased. In the sitting position, $\beta$ wave which reflects a state of alert consciousness was increased and both the sympathetic and parasympathetic nerves were activated. On the other hand, in the spine position, $\theta$ wave which signifies a state of relaxation was increased and heart rate (HR) was decreased. Activation of sympathetic and parasympathetic nerves was also observed in this position. Significant increases of indices related to awakening and concentration were observed accompanied by increase of HR and a sympathetic nerve was activated in the riding-horse position. In the present study, it was shown that each Qigong position caused various and significant changes in autonomic nervous system. It would be expected that these results can be applied in the choice of appropriate Qigong position according to objective of Qigong therapy although it is remained to further evaluate the effects of long-term maintenance of Qigong positions and repeated Qigong training.

• 한국한의학연구원논문집
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• 제17권2호
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• pp.85-100
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• 2011

Objectives : This study aimed to investigate the effect of four common types of Qigong position (standing, sitting, supine, and horse-riding position) on the autonomic nervous system. Method : Thirty healthy subjects participated in this study once a week for four weeks. Heart Rate Variability (HRV) was measured three times (before, during, and after the position) while the subject maintained one of four positions for ten minutes. Result : There were significant changes HRV in the standing position. In the sitting position, both the sympathetic and parasympathetic nerves were activated. On the other hand, in the spine position, heart rate (HR) was decreased. Activation of sympathetic and parasympathetic nerves was also observed in this position. Significant increases of indices related to awakening and concentration were observed accompanied by increase of HR and a sympathetic nerve was activated in the riding-horse position. Conclusions : In the present study, it was shown that each Qigong position caused various and significant changes in autonomic nervous system. It would be expected that these results can be applied to choose appropriate Qigong position according to objective of Qigong therapy although it is remained to further evaluate the effects of long-term maintenance of Qigong positions and repeated Qigong training.

• PNF and Movement
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• 제22권2호
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• pp.201-211
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• 2024

Purpose: This study aimed to evaluate the effects of trunk stabilization exercises using a Reformer on trunk control, balance ability, and gait function in chronic stroke patients. Methods: The participants were 24 chronic stroke patients, randomly divided into two groups: trunk stabilization exercise using the Reformer group (TS-R, n = 12) and general trunk stabilization exercise group (GT-E, n = 12). Assessment methods included the Trunk Impairment Scale for trunk control, the AMTI force platform for static balance, the Timed Up and Go test for dynamic balance, and the Dynamic Gait Index for gait function. Assessments were conducted before and after the intervention. The intervention for the TS-R group consisted of bridging exercises using a Reformer, while the GT-E group performed bridging exercises on a mat. All interventions were performed for 17 minutes per session, five times a week, for a total of 20 sessions over four weeks. Statistical analysis was performed using repeated-measures ANOVA to analyze the interaction between groups and time. Results: The results of the repeated measures ANOVA indicated a significant interaction between the groups and time. The TS-R group showed statistically significant differences in all variables before and after the intervention. In contrast, the GT-E group did not show statistically significant differences in any variables before and after the intervention. Conclusion: The findings of this study suggest that trunk stabilization exercises using a reformer are effective in improving trunk control, balance ability, and gait function in chronic stroke patients.

• Biomolecules & Therapeutics
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• 제2권2호
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• pp.190-205
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• 1994

This study was conducted to investigate the repeated dose toxicity of DA-125, a new anthracycline antitumor antibiotic, in rats. Before the 13-week main study, a 4-week dose-range finding (DRF) study was carried out. The administration of DA-125 intravenously at dosage levels of 0, 0.125, 0.5, 2.0, and 8.0 mg/kg/day to rats for 4 weeks resulted in premature deaths of all animals in the 8.0 mg/kg/day group and in the deaths of 4 males and 4 females at 2.0 mg/kg/day. Body weights were markedly reduced in the 8.0 mg/kg/day group and showed dose-related decreases in all treatment groups when compared with the control group. Reductions in weight gain were slight and not significantly different at 0.125 mg/kg/day but animals receiving 0.5 mg/kg/day showed more marked decreases in gain in a clear dose-related manner Based On the results of the above DRF study, a 13-week repeated dose intravenous toxicity study in rats with DA-125 was performed at a dose level of 0, 0.012, 0.08 and 0.3 mg/kg/day. No treatment related effects were noted in behavior or body weight in all treatment groups. One male at the highest dose level died on study day 26, but the death could not be related to test article toxicity. Swelling and scabbing of the ears was present in all of the groups, including the control group. There were no treatment related changes in the hematological, biochemical or urinalysis values in all treatment groups. Thymus weights were significantly reduced ill males receiving 0.3 mg/kg/day and they were sligltly, and not significantly, reduced in females of the same group. While there were no associated histological changes. Treatment related necrosis was found in the tail vein (injection site) at 0.08 and 0.3 mg/kg/day. On the basis of these results, the no observed effect level (NOEL) was 0.012 mg/kg/day and the maximum tolerated dose (MTD) was estimated to be more than 0.3 mg/kg/day under the conditions tested.

• 한국조경학회지
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• 제45권2호
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• pp.1-10
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• 2017

본 연구는 여행참여와 외상적 사건이 주관적 웰빙에 미치는 영향을 검증하였다. 이를 위하여, 긍정적 감정, 부정적 감정 그리고 삶의 만족도를 종속변수로, 여행참여 여부와 외상적 사건의 회상정도를 독립변수로 하여 유사실험을 설계하였다. 2~3주 간격으로 4번 수집한 종단자료를 반복측정 분산분석으로 분석한 결과, 여행참여는 긍정적 감정과 삶의 만족도를 향상시켰으며, 그 효과는 4주 이상 지속되어 여행은 사람들의 주관적 웰빙을 향상시키는 수단이라는 것을 밝혔다. 외상적 사건을 많이 회상한 집단은 부정적 감정이 사고 직후부터 높아졌으며, 그 영향은 7주 이상 지속되었다. 부정적 사건은 긍정적 사건보다 주관적 웰빙에 미치는 영향력이 강하며, 오래 가는 경향이 있기 때문이었다. 여행과 마찬가지로 도시공원 방문도는 즐거운 여가경험이기 때문에 본 연구의 결과를 적용해 도시공원이 중장기적으로 도시민의 주관적 웰빙을 증가 또는 유지시키며, 스트레스를 완화시킬 수 있는 수단이라는 점을 고찰하였다.

• International Journal of Contents
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• 제8권2호
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• pp.97-102
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• 2012

The purpose of this study was to investigate the effects of various cool-down exercises on muscular strength and endurance. After receiving a treadmill training for main exercise, the subjects conducted isotonic and isometric cool-down exercises four times for three weeks. Isotonic exercise with leg press of 10kg was repeated by 20 times and isometric exercise was conducted at flexion of hip joint and knee joint with leg press of 10kg by maintaining it for 6 sec and resting for 2 sec by 20 times. Muscular strength after exercise was measured with 1 RM by times and muscular endurance with maximum repetition frequency using time to keep for loading the weight of 10 RM and 65% of maximum muscular strength. As a result of comparing and analyzing measured values, exercise recovery shape of isotonic and isometric cool-down group were more effective than rest recovery shape of the control group. The isometric cool-down group was more effective than isotonic cool-down group. In conclusion, isometric exercise was more effective than isotonic exercise or simple rest on muscular strength and endurance.

• 대한간호학회지
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• 제35권2호
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• pp.372-381
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• 2005

Purpose: This study was to investigate the effects of a taping method on pain and ROM of the knee joint in the elderly. Method: The subjects were seniors registered in a senior welfare center in D city. An experimental group of 30 persons and acontrol group of 33 persons were chosen and according to the proper conditions and a knee pain score was marked from 1-5 on a Numerical Pain Rating Scale. For the experimental group, the taping method was conducted three times a week for four weeks (twelve times in all) but the control group did not receive taping.. The measuring instrument of knee pain was a numerical pain rating scale from 0 to 10 and the ROM score was the average value of three measured values with a goniometer. The data was analyzed with SPSS WIN 10.0 using an $x^2-test$, t-test, repeated measures ANOVA, and time contrast. Result: Knee joint pain was significantly decreased in the experimental group over that of the control group (p=.001). In addition, knee joint ROM of the experimental group was significantly improved over that of the control group (p=.001). Conclusion: It was proven that the taping method was effective for pain relief and increasing ROM of the knee joint in the elderly.

• Journal of Korean Neurosurgical Society
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• 제56권5호
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• pp.419-422
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• 2014

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by sudden-onset headache with focal neurologic deficit and prolonged but reversible multifocal narrowing of the distal cerebral arteries. Stroke, either hemorrhagic or ischemic, is a relatively frequent presentation in RCVS, but progressive manifestations of subarachnoid hemorrhage, intracerebral hemorrhage, cerebral infarction in a patient is seldom described. We report a rare case of a 56-year-old woman with reversible cerebral vasoconstriction syndrome consecutively presenting as cortical subarachnoid hemorrhage, intracerebral hemorrhage, and cerebral infarction. When she complained of severe headache with subtle cortical subarachnoid hemorrhage, her angiography was non-specific. But, computed tomographic angiography showed typical angiographic features of this syndrome after four days. Day 12, she suffered mental deterioration and hemiplegia due to contralateral intracerebral hematoma, and she was surgically treated. For recurrent attacks of headache, medical management with calcium channel blockers has been instituted. Normalized angiographic features were documented after 8 weeks. Reversible cerebral vasoconstriction syndrome should be considered as differential diagnosis of non-aneurysmal subarachnoid hemorrhage, and repeated angiography is recommended for the diagnosis of this under-recognized syndrome.

• The Journal of Advanced Prosthodontics
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• 제3권2호
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• pp.76-80
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• 2011

PURPOSE. Implant stability quotient (ISQ) values have been supposed to predict implant stability. However, the relationship between ISQ values and bone-to-implant contact ratio (BIC%) which is one of the predictors of implant stability is still unclear. The aim of the present study was to evaluate initial ISQ values in relation to BIC% using rabbit model. MATERIALS AND METHODS. Four New Zealand white rabbits received a total of 16 implants in their tibia. Immediately after implant placement ISQ values were assessed. The measurements were repeated at the time of sacrifice of the rabbits after 4 weeks. Peri-implant bone regeneration was assessed histomorphometrically by measuring BIC% and bone volume to total volume values (bone volume %). The relationships between ISQ values and the histomorphometric output were assessed, and then, the osseointegration prediction model via the initial ISQ values was processed. RESULTS. Initial ISQ values showed significant correlation with the BIC%. The bone volume % did not show any significant association with the ISQ values. CONCLUSION. In the limitation of this study, resonance frequency analysis is a useful clinical method to predict the BIC% values and examine the implant stability.

• 대한간호학회지
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• 제34권5호
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• pp.760-770
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• 2004

Purpose: This study was done to identify the effects of weight-bearing exercise(WBE) on bone metabolism. Method: WBE was performed for 12 weeks by healthy college women. Bone-related parameters were measured four times during this period by evaluating the immunoradiometric assay and enzyme immunoassay. Bone mineral densities(BMDs) were measured by dual energy x-ray absorptiometry before and after the WBE program. Data was analyzed using t-test, paired t-test, $x^2$-test, and repeated measures ANOVA. Result: Osteocalcin, a bone formation marker, increased more in the experimental group than in the control group based on the interaction between time and group(F=3.29 p=.024). Little difference between the two groups was found for the other parameters: urinary deoxypyridinoline, insulin-like growth factorI, parathormone, serum calcium, and serum phosphorus without showing any time interaction between the groups. The femoral trochanter BMD rose in the experimental group while that of the control group fell, showing a significant difference for BMD(t=3.06 p=.005). However, there was no significant difference between the two groups for changes in BMD of the forearm, lumbar spine, femoral neck, and femoral ward's triangle. Conclusion: These findings supported the WBE is beneficial for increasing bone formation in college women and long-term application is needed to substantiate the effects of WBE as a intervention in promotion of bone-health.