• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.10
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• pp.1466-1470
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• 2009

This study was focused on the development of anticariogenic edible films using pullulan containing grapefruit seed extract (GFSE), polylysine or propolis. According to the result of antimicrobial activity (disc diffusion method) of GFSE, polylysine and propolis against Streptococcus mutans, antimicrobial pullulan film was produced by adding grapefruit seed extract. The optimum combination of pullulan and sorbitol (plasticizer) was 10$\sim$15% (w/v) and 40$\sim$50% of pullulan (w/w), respectively. Minimum concentration of grapefruit seed extract for growth inhibition of Str. mutans was 50 ppm in medium. Formulation of antimicrobial pullulan films containing grape seed extract was established and these results evidently showed potential for commercial application.

• Research in Plant Disease
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• v.23 no.3
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• pp.268-277
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• 2017

Fusarium head bight (FHB) is a devastating disease on major cereal crops worldwide which causes primarily by Fusarium graminearum. Synthetic fungicides are generally used in conventional agriculture to control FHB. Their prolonged usage has led to environmental issues and human health problems. This has prompted interest in developing environmentally friendly biofungicides, including botanical fungicides. In this study, a total 100 plant extracts were tested for antifungal activity against F. graminearum. The crude extract of Pterocarpus santalinus heartwood showed the strongest antifungal activity and contained two antifungal metabolites which were identified as ${\alpha}$-cedrol and widdrol by GC-MS analysis. ${\alpha}$-Cedrol and widdrol isolated from P. santalinus heartwood extract had 31.25 mg/l and 125 mg/l of minimal inhibitory concentration against the spore germination of F. graminearum, and also showed broad spectrum antifungal activities against various plant pathogens. In addition, the wettable powder type formulation of heartwood extract of P. santalinus decreased FHB incidence in dose-dependent manner and suppressed the development of FHB with control values of 87.2% at 250-fold dilution, similar to that of chemical fungicide (92.6% at 2,000-fold dilution). This study suggests that the heartwood extract of P. santalinus could be used as an effective biofungicide for the control of FHB.

• Culinary science and hospitality research
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• v.17 no.3
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• pp.132-140
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• 2011

The objective of this study is to evaluate the quality characteristics of turmeric powder Dasik, a Korean traditional cookie, prepared by different additions of turmeric powder(0%, 1%, 2%, 3%, 4%). The result of the study is as follows. As the level of turmeric powder in the formulation increased, the moisture contents of the samples increased. As the content of the turmeric powder increased, the L-values of the turmeric powder Dasik significantly decreased, and the a- and b-values also significantly increased. Also, the hardness, gumminess, springiness, cohesiveness and chewiness of the turmeric powder Dasik increased, whereas its adhesiveness decreased as the amount of turmeric powder increased. The sensory evaluation results showed that the 2% turmeric powder sample showed the highest preference scores; therefore, the 2% turmeric powder Dasik prepared with 98g of flour, 2g of turmeric powder, and 80g of honey was chosen as the most preferred product. It is expected that the development of Dasik added with functional food such as turmeric powder can influence the use of turmeric and increase the consumption of Korean traditional cookies.

• Journal of Pharmaceutical Investigation
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• v.31 no.2
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• pp.89-94
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• 2001

The pharmacokinetics of recombinant human granulocyte colony stimulating factor (rhG-CSF) following intravenous (i.v.), intramuscular (i.m.) and subcutaneous (s.c.) administration of HM1041l-lyo and HM10411-liq (lyophilized and liquid formulations of rhG-CSF, recently under development by Hanmi Pharmaceutical Company) were studied in rats, and compared with that of Filgrastim (conventional formulation of rhG-CSF on market). The plasma concentration of rhG-CSF was quantified using a specific ELISA. The pharmacokinetic parameters of rhG-CSF, after i.v., i.m. and s.c. administration of Filgrastim, HM1041l-lyo and HM1041l-liq to rats at a rhG-CSF dose of $10\;{\mu}g/kg$, were almost identical among the three formulations. No dose-dependency was observed in the pharmacokinetic parameters of rhG-CSF following i.v. administration in the dose range of $5{\sim}100\;{\mu}g/kg$. rhG-CSF, after i.v. administration of the three preparations at a dose of $10\;{\mu}g/kg$ to rats, was detected at low levels in all of the body tissues with highest tissue/plasma ratio of $0.46{\sim}0.51$ for the kidney at 30 min after the administration. The pharmacokinetics of rhG-CSF, after i.v. administration to mice at a dose of $10\;{\mu}g/kg$, were comparable among the three formulations. In conclusion, HM10411-lyo and HM10411-liq exhibited similar pharmacokinetics for rhG-CSF with Filgrastim regandless of animal species. Considering the fact that HM10411 series, contrary to Filgrastim, are proteins lacking a methionine residue, the methionine moiety in rhG-CSF molecule does not appear to influence the pharmacokinetics of the protein significantly.

• Journal of Korean Society of Transportation
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• v.20 no.3
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• pp.129-147
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• 2002

This paper presents a variational equality formulation by Providing new dynamic route choice condition for a link-based dynamic traffic assignment model. The concepts of used paths, used links, used departure times are employed to derive a new link-based dynamic route choice condition. The route choice condition is formulated as a time-dependent variational equality problem and necessity and sufficiency conditions are provided to prove equivalence of the variational equality model. A solution algorithm is proposed based on physical network approach and diagonalization technique. An asymmetric network computational study shows that ideal dynamic-user optimal route condition is satisfied when the length of each time interval is shortened. The I-394 corridor study shows that more than 93% of computational speed improved compared to conventional variational inequality approach, and furthermore as the larger network size, the more computational performance can be expected. This paper concludes that the variational equality could be a promising approach for real-time application of a dynamic traffic assignment model based on fast computational performance.

• Journal of Environmental Impact Assessment
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• v.26 no.1
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• pp.78-92
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• 2017

Environmental impact assessment(EIA) on the construction and operation of thermal power plant(TPP) is aimed at promoting sustainable coastal development by clearly identifying the marine physics and organisms effects of the project on the surrounding marine environment and minimizing its impact. The primary purpose of this study is to establish EIA guidelines for TPP in order to assess how TPP construction projects influence marine environment and to establish the mitigaion plans of environmental impacts. Through this study, scientific and efficient EIA guidelines for the marine environments were established by a specialist forum consisted of officials from the Ministry of Environment and the Ministry of Trade, Industry and Energy, personnel from five public corporations in charge of TPPs and marine environment experts. In the study, fifteen EIA reports (2009~2015) on TPPs submitted were analyzed to identify the shortcomings of current assessment items on marine environment and to collect a wide range of information including EIA report formulation regulations, domestic and overseas environmental survey guidelines and EIA review comments on TPPs. Based on the findings, a specialist forum put together EIA guidelines for TPP construction projects.

• Journal of the Korean Society for Marine Environment & Energy
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• v.7 no.4
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• pp.192-198
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• 2004

A numerical method is developed to solve a two-dimensional diffraction problem for a body located in a sediment pocket where a heavier muddy water is trapped. In the present study, the wave exciting forces acting on a submerged body in the water-sediment interface by an incident wave is investigate. It is assumed that the heavier mud is trapped locally in a sediment pocket. A mathematical formulation is made in the scope of the potential theory. The fluid is assumed to be inviscid, incompressible and its motion irrotational. The boundary conditions on the unknown free surface and interface are linearized. As a method of solution, the localized finite-element method is adopted. In the method, the computation domain is reduced by utilizing the complete set of analytic solutions known in the infinite subdomain to be truncated by introduction of an appropriate juncture conditions. The main advantage of this method is that any complex geometry of the boundaries can be easily accommodated. Computations are carried out for mono-chromatic plane progressive surface waves normally incident on the domain. Numerical results are compared with those obtained by Lassiter based on Schwingers variational method. Good Agreements are obtained in general. Another numerical computations are made for the cases with and without a body in the sediment pocket.

• The Korean Journal of Pesticide Science
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• v.20 no.2
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• pp.83-92
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• 2016

New tree wound-treatment formulations (WTF) were developed in this study. Stimulating effects of plant growth regulating substance on callus formation were evaluated in vivo twig disc culture of Zelkova serrata, Ziziphus jujuba, Pinus densiflora, Ginkgo biloba. and Aesculus turbinata. Based on the evaluation, WTF were prepared with 2,4-D, NAA, and IBA using xanthan gum as an extending agent. WTF were pasted on $2{\times}10cm$ artificial wound on the stem and the effects were evaluated 12 weeks later with the thickness of new callus-tissues. The effects varied with tree species and the growth regulators. In Z. serrata and A. turbinata, 2 mg/L of 2,4-D was the best WTF. In P. koraiensis and G. biloba, 8 mg/L of NAA and 1 mg/L of IBA were the best, respectively. Callus formation was quite lower in G. biloba compared to other species. Stimulating effect of thiophanate-methyl paste was excellent only in Z. serrata and lower than certain WTF in other species. Vaseline, which was used generally as an WTF, remained longer on the wound and causing decay. From the results, it could be recommended that 2,4-D, NAA and IBA were the best WTF for Z. serrata/A. turbinata, P. koraiensis and G. biloba, respectively.

• The KIPS Transactions:PartA
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• v.16A no.6
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• pp.411-418
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• 2009

Vector quantization algorithm based on fuzzy clustering has been widely used in the field of data compression since the use of fuzzy clustering analysis in the early stages of a vector quantization process can make this process less sensitive to its initialization. However, the process of fuzzy clustering is computationally very intensive because of its complex framework for the quantitative formulation of the uncertainty involved in the training vector space. To overcome the computational burden of the process, this paper introduces an array architecture for the implementation of fuzzy vector quantization (FVQ). The arrayarchitecture, which consists of 4,096 processing elements (PEs), provides a computationally efficient solution by employing an effective vector assignment strategy during the clustering process. Experimental results indicatethat the proposed parallel implementation providessignificantly greater performance and efficiency than appropriately scaled alternative array systems. In addition, the proposed parallel implementation provides 1000x greater performance and 100x higher energy efficiency than other implementations using today's ARMand TI DSP processors in the same 130nm technology. These results demonstrate that the proposed parallel implementation shows the potential for improved performance and energy efficiency.

• Korean Journal of Soil Science and Fertilizer
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• v.29 no.4
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• pp.396-402
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• 1996

This study was conducted to determine the effect of treatment with the plant-growth-promoting bacteria on the growth and yield of red pepper(Capsicum annuum L.) with different soil electrical conductivity(EC) levels. The mixed liquid culture was done pseudomonas P and saboraud dextrose medium. The isolated bacteria(IB) were inoculated by spray of 3.7ml at 1/2000a pot filled with different soil electrical conductivity level(2.9, 8.6, 11.5dS/m) every week, respectively, with mixed liquid culture (Pseudomonas P+Sabouraud dextrose) of eight strains. The plant height of red pepper with IBs treatment in different soil EC levels showed better growth than IBs nontreatment in the order of the 2.9>8.6>11.5 dS/m. The yield of pepper with IBs treatment in different soil EC level was higher in 13% than IBs nontreatment and chemical properties($P_2O_5$, K, Ca, Mg) of the soil after harvest in IBs treatment were slightly increased, while organic matter and EC of IBs treatment were slightly decreased than those of IBs nontreatment. Moisture content of the soil after the harvesting with IBs treatment was slightly increased than IBs nontreatment.