• Title/Summary/Keyword: Forming pressure

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Study on Application of Skin Care Cosmetic and Stabilization of Idebenone by Forming Niosome Vesicle Technology

  • Kim, In-Young
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.2
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    • pp.592-599
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    • 2019
  • This study is to stabilize insoluble and unstable active ingredient which is Idebenone (INCI name: hydroxydecyl ubiquinone) in a multi-lamellar vesicle (MLV) and to stabilize it in the skin care cosmetics. Idebenone is good effective raw material in the treatment of Alzheimer's disease in the medical field and a powerful antioxidant in dermatology. It is well known as a substance that inhibits the formation of melanin and cleans the skin pigment. However, it did not dissolve in any solvent and it was difficult to apply in cosmetic applications. Niosome vesicle was able to develop a nano-particle by making a multi-layer of idebenone encapsulated with a nonionic surfactant, hydrogenated lecithin and glycine soja (soybean) sterols and passing it through a high pressure microfluidizer. Idebenone niosome vesicle (INV) has been developed to have the ability to dissolve transparently in water and to promote transdermal penetration. The appearance of the INV was a yellowish liquid having specific odor, and the particle size distribution of INV was about 10~80 nm. The pH was 5~8 (mean=6.8). This capsulation with idebenone was stored in a $45^{\circ}C$ incubator for 3 months and its stability was observed and quantitatively measured by HPLC. As a result, the stability of the sample encapsulated in the niosome vesicle (97.5%) was about 66.3% higher than that of the non-capsule sample of 32.5%. Idebenone 1% INV was used for the efficacy test and clinical trial evaluation as follows. The anti-oxidative activity of INV was 38.2%, which was superior to that of 12.8% tocopherol (control). The melanin-reducing effect of B16 melanoma cells was better than INV (17.4%) and Albutin (control) (9.6%). Pro-collagen synthesis rate was 128.2% for INV and 89.3% for tocopherol (control). The skin moisturizing effect was 15.5% better than the placebo sample. The elasticity effect was 9.7% better than the placebo sample. As an application field, INV containing 1% of idebenone is expected to be able to develop various functional cosmetic formulations such as skin toner, ampoule essence, cream, eye cream and sunblock cream. In addition, it is expected that this encapsulated material will be widely applicable to emulsifying agents for skin use in the pharmaceutical industry as well as the cosmetics industry.

Concrete-Panel Retaining Wall anti-crack sleeve inserted (균열방지 슬리브가 매설된 패널식 옹벽)

  • Jang, Sung-Ho;Chung, Jee-Seung
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.3
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    • pp.345-349
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    • 2019
  • In Korea, the mountainous area occupies more than 70% of the whole country, cutting of earth slope that cuts a part of the ground surface is widely used when building infrastructures such as road, railroad, and industrial complex construction. In recent years, regulations on environmental damage have become more strict, and various methods have been developed and applied. Among them, Concrete-Panel Retaining Wall technique is actively applied. Concrete-Panel Retaining Wall is a method to resist horizontal earth pressure by forming a wall by attaching a precast retaining wall to the front of the support material and increasing the shear strength of the disk through reinforcement of the support material. Soil nailing, earth bolt, and ground anchor are used as support material. Among them, ground anchor is a more aggressive reinforcement type that introduces tensile load in advance to the steel wire, and a large concentrated load acts on the front panel. This concentrated load is a factor that creates cracks in the concrete panel and reduces the durability of the retaining wall itself. In this study, steel pipe sleeves and reinforcements were purchased at the anchorage of the panel to prevent cracks, and by applying bumpy shear keys to the end of the panel, the weakness of the individual behavior of the existing grout anchors was improved. The problem of degraded landscape by exposure to front concrete of retaining wall and protrusion of anchorage was solved by the production of natural stone patterns and the construction of sections that do not protrude the anchorage. In order to verify the effectiveness of anti-crack sleeves and reinforcements used in the null, indoor testing and three-dimensional numerical analysis have been performed, and the use of steel pipe sleeves and reinforcements has demonstrated the overall strength increase and crack suppression effect of panels.

Enhancement of combustion efficiency of a air-cooled combustor system with single F.D. Fan Using CFD (전산유체역학을 이용한 단일 송풍기가 적용된 공냉식 연소설비의 효율개선)

  • Kim, Min-Choul;Shon, Byung-Hyun;Lee, Jae-Jeong;Park, Hung-Suck
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.460-468
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    • 2021
  • This study investigated the enhanced combustion efficiency of an "air-cooled combustion system" with single F.D. fan, and performed a numerical analysis for the operation and design conditions to increase the combustion efficiency. The combustion efficiency in an actual combustor was compared before and after the structure modification. Numerical analysis for application of a single fan revealed the difficulty of forming a turbulence for circular combustion conditions. This is because the supply ratio of combustion air supplied into 2 flow paths becomes irregular in the combustion furnace due to a change in friction force and pressure in each flow path. Subsequently, two methods of supplying air into the combustion furnace were analyzed numerically to obtain the optimal combustion conditions of an air-cooled combustion system. The first method involved injecting the preheated combustion air after a 180~360 degree rotation from the outer wall, whereas in the second method, the combustion air was injected into the combustion furnace in a tangential direction after primary heat exchange outside the combustion furnace, by applying a rotatable vane structure in the combustion furnace. Results reveal that application of a single F.D. fan to the air injection into a rotatable combustion furnace is desirable for optimization of the combustion conditions for applying a duct structure having a dual cooling wall for the cooling of the outer wall of the combustion furnace, and for maintaining perfect mixing in the combustion furnace. We therefore confirmed enhanced combustion efficiency by comparing the actual combustion efficiency before and after structure modification.

A Study on the Release Characteristics During Wafer-Level Lens Molding Using Thermosetting Materials (열경화성 소재를 사용한 웨이퍼 레벨 렌즈 성형 중 이형 특성에 관한 연구)

  • Park, Si-Hwan;Hwang, Yeon;Kim, Dai-Geun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.461-467
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    • 2021
  • Among the defect factors that can occur when a wafer-level lens is molded using a thermosetting material, the mold sticking problem of a molded lens during the release process can damage the molded substrate and deform the substrate at the wafer level. An experiment was conducted to examine the factors affecting the demolding force in the lens forming process. The demolding force was examined according to the coating material of the molds. The mold was surface-treated with ITO and Ti, followed by plasma treatment in an O2 atmosphere. A DLC coating was then performed, and the curing and releasability were examined. A coating method for the pull-off experiment was selected based on the results. To measure the demolding force according to the curing process conditions, a method of curing at a constant pressure and a method of curing at a constant position were applied. As a result, the TiO2 surface treatment reduced the release force. When cured by controlling the location, curing shrinkage can reduce the adhesion energy of the interface during curing, resulting in better demolding.

Numerical study on the foam spraying for AFDSS applicable to initial fire suppression in large underground spaces (지하대공간 초동 화재진압에 적용가능한 자율형 소화체계의 폼 분사 해석 기법 연구)

  • Park, Jinouk;Yoo, Yongho;Kim, Whiseong
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.23 no.6
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    • pp.503-516
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    • 2021
  • Autonomous fire detection and suppression system requires advanced technology for complex detection technology and injection/control technology for accurate hitting by fire location. Also, foam spraying should be included to respond to oil fires. However, when a single spray monitor is used in common, water and foam spray properties appear different, so for accurate fire suppression, research on the spray trajectory and distance will be required. In this study, experimental studies and numerical analysis studies were combined to analyze the foam spray characteristics through the spray monitor developed for the establishment of an autonomous fire extinguishing system. For flow analysis of foam injection, modeling was performed using OpenFOAM analysis software, and the commonly used foaming agent (Aqueous Film-Forming Foam) was applied for foam properties. The injection distance analysis was performed according to the injection pressure and the injection angle according to the form of the foam, and at the same time, the results were verified and presented through the injection experiment.

Depositional Processes of Pyroclastic Density Currents in Lacustrine Environments: An Example from the Cretaceous Jeonggaksan Formation in Danjang-myeon, Miryang City (호수 내 화쇄밀도류의 퇴적과정: 밀양시 단장면 일원 백악기 정각산층의 예)

  • Gihm, Yong Sik;Park, Seung-Ik
    • Economic and Environmental Geology
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    • v.55 no.3
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    • pp.295-307
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    • 2022
  • We studied the Cretaceous Jeonggaksan Formation to determine depositional processes of pyroclastic density currents entering into the lacustrine environments. This formation is composed largely of sandstone-mudstone couplets and (tuffaceous) normally graded sandstones deposited in lacustrine environments, interbedded with two pyroclastic beds: welded massive lapilli tuff and normally graded lapilli tuff. The welded massive lapilli tuff (10 m thick) is composed of poorly sorted, structureless lapilli supported by a welded ash matrix. The normally graded lapilli tuff (4 m thick) is characterized by moderately to well sorted natures and multiple normally graded divisions in the lower part of the bed with internal boundaries. The contrasting depositional features between these lapilli tuff are suggestive of different physical characteristics and depositional processes of pyroclastic density currents in the lake. Overall poorly sorted and massive natures of the thick, welded massive lapilli tuff are interpreted to have been formed by rapid settling of pyroclastic sediments from highly concentrated and sustained pyroclastic density currents. In this case, the pyroclastic density currents were able to displace lake water from shoreline and the pyrolclastic density currents preserved their own heat except for frontal parts of the currents. As a result, welded textures can be formed despite entrance of pyroclastic density currents into the lake. The internal boundaries of the normally graded lapilli tuff reflect unsteady natures of the pyroclastic density currents at the time of the deposition and the pyroclastic density currents can not provide sufficient pressure to displace lake water. As a consequence, the pyroclastic density currents transformed into water-saturated turbidity currents, forming relatively well sorted, normally graded lapilli tuff.

Fabrication of Porous Cu Layers on Cu Pillars through Formation of Brass Layers and Selective Zn Etching, and Cu-to-Cu Flip-chip Bonding (황동층의 형성과 선택적 아연 에칭을 통한 구리 필라 상 다공성 구리층의 제조와 구리-구리 플립칩 접합)

  • Wan-Geun Lee;Kwang-Seong Choi;Yong-Sung Eom;Jong-Hyun Lee
    • Journal of the Microelectronics and Packaging Society
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    • v.30 no.4
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    • pp.98-104
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    • 2023
  • The feasibility of an efficient process proposed for Cu-Cu flip-chip bonding was evaluated by forming a porous Cu layer on Cu pillar and conducting thermo-compression sinter-bonding after the infiltration of a reducing agent. The porous Cu layers on Cu pillars were manufactured through a three-step process of Zn plating-heat treatment-Zn selective etching. The average thickness of the formed porous Cu layer was approximately 2.3 ㎛. The flip-chip bonding was accomplished after infiltrating reducing solvent into porous Cu layer and pre-heating, and the layers were finally conducted into sintered joints through thermo-compression. With reduction behavior of Cu oxides and suppression of additional oxidation by the solvent, the porous Cu layer densified to thickness of approximately 1.1 ㎛ during the thermo-compression, and the Cu-Cu flip-chip bonding was eventually completed. As a result, a shear strength of approximately 11.2 MPa could be achieved after the bonding for 5 min under a pressure of 10 MPa at 300 ℃ in air. Because that was a result of partial bonding by only about 50% of the pillars, it was anticipated that a shear strength of 20 MPa or more could easily be obtained if all the pillars were induced to bond through process optimization.

The crenulation of Ogcheon metasedimentary rocks near the Ogcheon granite and the Honam shearing, Korea (옥천화강암 부근 옥천 변성퇴적암류의 파랑습곡구조와 호남전단운동)

  • Kang, Ji-Hoon
    • The Journal of the Petrological Society of Korea
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    • v.19 no.2
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    • pp.157-165
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    • 2010
  • The age unknown Ogcheon metasedimentary rocks and the Jurassic Ogcheon granite (Jocgr) intruding it are distributed in the Ogcheon area, which is located in the central part of the Ogcheon Belt, Korea, This paper newly examines the timing of Honam shearing on the basis of the microstructural researches on time-relationship between the crenulation of Ogcheon metasedimentary rocks and the contact metamorphism by the intrusion of Jocgr. The D2 crenulation phase, which is defined by the microfolding of the S1 foliation in the metasedimentary rocks, is divided into two sub-phases. The one is a sub-phase of Early crenulation (D2a) which is included within old andalusite porphyroblasts, and the other is that of Late crenulation (D2b) which warps around the old andalusite. But they show the same dextral shear sense, the axial planes parallel to each other, and a single crenulation at outcrop scale. The contact metamorphism of andalusite-sillimanite type by the Jocgr occurred during the inter-phases of D2a and D2b, and crystallized the old andalusite masking the D2a crenulation and fibrous sillimanites replacing the D2a crenulation-forming muscovites. New andalusite porphyroblasts synkinematically grew in pressure shadows around the old andalusite or in its outermost mantles during the early stage of the D2b. The D2b occurred still continuously after the growth of the andalusite ceased (= later stage of the D2b). It indicates that the D2b occurred continuously during the period when the Ogcheon granite was still hot and cool. From this study, the crenulation history of Ogcheon metasedimentary rocks and the timing of Honam shearing would be newly established and reviewed as follows. (1) Early Honam shearing; formative period of Early crenulation, (2) main magmatic period of Jurassic granitoids; growth of the old andalusite and fibrous sillimanite by the intrusion of Jocgr, (3) main cooling period of Jurassic granitoids; formative period of Late crenulation related to Late Honam shearing, growth of the new andalusite in the early stage of D2b. Thus, this study proposes that the Honam shear movement would occur two times at least before and after the intertectonic phase which corresponds to the main magmatic period of Jurassic granitoids.

Division of Soil Properties in Reclaimed Land of the Mangyeong and Dongjin River Basin and Their Agricultural Engineering Management (만경강과 동진강 유역 간척농경지 토양특성 구분과 농공학적 관리 대책)

  • Hwang, Seon-Woong;Kang, Jong-Gook;Lee, Kyung-Do;Lee, Kyung-Bo;Park, Ki-Hun;Chung, Doug-Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.3
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    • pp.444-450
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    • 2012
  • The physical and chemical properties of soil in the Mangyeong and Dongjin river basin had been investigated in order to establish the most optimum soil improvement plan on the reclaimed land. The total soil area by reclamation in Saemangeum basin is 113,971 ha. The classification by the distribution of soil series and soil texture is as following. 13 soil series including Chonnam, Buyong and Chonbuk series are period-unknown areas. Regarding the soil texture, they are fine silty ~ clayey very fine. From 1920s to 1960s, Mangyeong, Gwanghwal and Chonbuk series had coarse silty textured soil. After the 1970s, Mangyeong, Gwanghwal, Munpo, Yeompo, Poseung, Gapo and Hasa series have more sandy soil ~ moderately coarse loamy textured soil. Regarding the chemical properties, the concentrations of EC, Exch. $K^+$, $Mg^{2+}$, $Na^+$ and pH are high regardless of the time of reclamation. On the other hand, organic matter (OM) of top soil were 3.3~16.1 g $kg^{-1}$. The organic matter contents were very low though the soil had been farmed for a long time. Furthermore, the deep soil had almost no organic matter with 5.6~1.1 g $kg^{-1}$. The reason is believed that there had not been any movement of OM and clay because pressure or induced pans had been formed by large agricultural machineries and poor vertical drain. Regarding the forming of illuvial horizon (B layer) which tells the development extent of soil, only in the Hwapo reclaimed area where rice had been cultivated for past 90 years, Fe and Mn from top soil are deposited at underground 20~30 cm with 7~8 cm thickness by the movement of clay. It is believed that it had been possible because the earthiness is silty clay loam soil with relatively high content of clay. The soils are soil with concern of damage from sea water, soil on flimsy ground and sandy soil. Therefore, soil improvement for stable crop production can be expected; if the water table would be lowered by subsurface drainage, the water permeability would be enhanced by gypsum and organic matter, and the sandy soil would be replaced by red soil with high content of clay.

Skarn Evolution and Fe-(Cu) Mineralization at the Pocheon Deposit, Korea (한국 포천 광상의 스카른 진화과정 및 철(-동)광화작용)

  • Go, Ji-Su;Choi, Seon-Gyu;Kim, Chang Seong;Kim, Jong Wook;Seo, Jieun
    • Economic and Environmental Geology
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    • v.47 no.4
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    • pp.335-349
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    • 2014
  • The Pocheon skarn deposit, located at the northwestern part of the Precambrian Gyeonggi massif in South Korea, occurs at the contact between the Cretaceous Myeongseongsan granite and the Precambrian carbonate rocks, and is also controlled by N-S-trending shear zone. The skarn distribution and mineralogy reflects both structural and lithological controls. Three types of skarn formations based on mineral assemblages in the Pocheon skarn exist; a sodiccalcic skarn and a magnesian skarn mainly developed in the dolostone, and a calcic skarn developed in the limestone. Iron mineralization occurs in the sodic-calcic and magnesian skarn zone, locally superimposed by copper mineralization during retrograde skarn stage. The sodic-calcic skarn is composed of acmite, diopside, albite, garnet, magnetite, maghemite, anhydrite, apatite, and sphene. Retrograde alteration consists of tremolite, phlogopite, epidote, sericite, gypum, chlorite, quartz, calcite, and sulfides. Magnesian skarn mainly consists of diopside and forsterite. Pyroxene and olivine are mainly altered to tremolite, with minor phlogopite, talc, and serpentine. The calcic skarn during prograde stage mainly consists of garnet, pyroxene and wollastonite. Retrograde alteration consists of epidote, vesuvianite, amphibole, biotite, magnetite, chlorite, quartz, calcite, and sulfides. Microprobe analyses indicate that the majority of the Pocheon skarn minerals are enriched by Na-Mg composition and have high $Fe^{3+}/Fe^{2+}$, $Mg^{2+}/Fe^{2+}$, and $Al^{3+}/Fe^{2+}$ ratios. Clinopyroxene is acmitic and diopsidic composition, whereas garnet is relatively grossular-rich. Amphiboles are largely of tremolite, pargasite, and magnesian hastingsite composition. The prograde anhydrous skarn assemblages formed at about $400^{\circ}{\sim}500^{\circ}C$ in a highly oxidized environment ($fO_2=10^{-23}{\sim}10^{-26}$) under a condition of about 0.5 kbar pressure and $X(CO_2)=0.10$. With increasing fluid/rock interaction during retrograde skarn, epidote, amphibole, sulfides and calcite formed as temperature decreased to approximately $250^{\circ}{\sim}400^{\circ}C$ at $X(CO_2)=0.10$.