• Applied Microscopy
• /
• v.24 no.1
• /
• pp.28-40
• /
• 1994

Xerostomia and xerophthalmia are delicate or serous side effects, occuring when the radiotherapy is administered to the head and neck cancer patient. It is known that the cause of the above side effect is radiosensitivity of serous cells. In this study, the ultrastructural features of the parotid glands of the X-irradiated rats were observed. Sprague-Dawley rats weighing 200-250g each were anesthetized with sodium thiopental, and placed on the Mitsubishi linear accelerator. Only the head and neck areas of animals were exposured at the distance of 80cm, within the area of $30X30cm$, in the depth of 1cm, with the speed of 200R/min. Total doses applied were 3,000R or 6,000R depending on the experimental groups. Animals were sacrificed on the 6th hour, 2nd day and 6th day after the irradiation. Parotid glands were fixed in the 2.5% glutaraldehyde-1.5% paraformaldehyde solution, and followed by refixation in the 1% osmium tetroxide solution. Dehydrated blocks were embedded in araldite mixture, and ultrathin sections were cut. Sections were contrasted with the solution of uranyl acetate and lead citrate, and observed with JEM 100 CX-II electron microscope. The results were as follows: 1. Normal parotid acinar cells are two types; the light and the dark acinar cells. The light acinar cell contains dense secretory granules, whereas dark acinar cells contains granules of medium density with some darker spots within them, or other cells contain granules of medium density with darker rims. 2. Six hours after the irradiation, many acinar cells were degenerated showing variable stages of cytolytic bodies, light bodies, or dense degenerations. Within the acinar cell, Golgi apparatus and granular endoplasmic reticula were most severely altered elements. Granules showed more contrasting densities and irregularities. 3. Two days after the irradiation, some cytolytic bodies, and focal lucent degeneration of cytoplasm, and fine granular alteration of cytoplasmic matrix were pronounced. But other elements including secretory granules are rather looked unlatered. 4. Six days after the irradiation, most severe alterations were seen. Many intracellular canaliculi (or secretion figures), quanta of cytoplasm containing secretion antecedants, severely irregular luminal border, and again contrasting density of secretory granules showing tigroid spots or dense rims were noted. And myoepithelial degenerations were observed not uncommonly. 5. Irregular densities of secretory granules were interpreted as abnormal components of protein or carbohydrate portion are synthesized or abnormally metabolized under severe X-irradiation. 6. Myoepithelial degeneration and related alteration of nerve endings, etc., were suggested as the other causes of xerostomia following X-irradiation. 7. It is requested that radiation doses should be arranged, considering in mind not only the sensitivity of acinar cells but also the myoepithelial and neural functions.

• The Journal of Industrial Distribution & Business
• /
• v.10 no.3
• /
• pp.35-44
• /
• 2019

Purpose - The purpose of this study is to empirically investigate the effect of choice of cause on the purchase intention by dividing it into the situation selected by the consumer and the company. This study also examines the moderating effect of cause options diversity and company-cause fit on the relationship between choice of cause and purchase intention. This will provide the theoretical information necessary to gain an in-depth understanding of the consumer's intention to purchase the cause-related marketing campaign, and in practice, it is expected that companies will be able to obtain useful information for effective planning and execution of the cause-related marketing campaign. Research design, date, and methodology - This study's survey was carried out on the college students of university located in Shandong, China. It was from November 4-11, 2018, and a total of 440 questionnaires were distributed, with 424 collected. Of them, effective questionnaires used in the final study were a total of 400 except 24 that couldn't be used. In this study, empirical analysis was done with frequency analysis, reliability analysis, analysis of variance and simple effect analysis by using Statistics Package SPSS 20.0. Results - The results are reported below: first of all, in the cause-related campaign consumers are more willing to buy the products when they are allowed to choice the focal cause of charity than when the company selects the cause of charity. Furthermore, the positive effect of allowing consumers to choice the cause of charity (vs. company choice) on purchase intentions is greater for high cause diversity to select. Finally, the positive effect of allowing consumers to choice the cause of charity (vs. company choice) on purchase intentions is greater when perceived fit between the company and the cause charity is low. Conclusions - This study extends the scope of the consumer perspective from consumer purchase intention research to the choice of cause in the cause-related marketing. When consumers select the cause, it would be better to provide the cause charity in diversifying selection and provide options for low fit between company and cause charity.

• Journal of the Korean earth science society
• /
• v.34 no.1
• /
• pp.59-68
• /
• 2013

Focal mechanism solutions in the southwestern region of the Korean Peninsula ($34^{\circ}N-36^{\circ}N$, $126^{\circ}E-128^{\circ}E$) were obtained from the analysis of the recent 22 earthquakes ($M{\geq}2.0$) occurred from January, 2005 to March, 2011. The spatial differences between the epicenters recalculated by this study and those by KMA (Korea Meteorological Administration) and KIGAM (Korea Institute of Geoscience and Mineral Resources) are less than $0.05^{\circ}$, indicating a small deviation. However, they become a little bit larger in the coastal area due to a biased arrangement of seismic stations. Redetermined depths of hypocenters show a difference less than 12.7 km by comparison with the depth data announced by KIGAM. Most epicenters in inland area are located closely to the lineaments. Fault plane solutions were obtained from the analysis of P and SH wave polarities, and SH/P amplitude ratios. They show strike-slip faulting or strike-slip faulting with reverse components dominantly. The P-axes trends are mainly ENE-WSW or E-W directions. The direction of fault plane and auxiliary plane with 'NNE-SSW and WNW-ESE' or 'NE-SW and NW-SE' are dominant and almost parallel to the general trends of lineaments in the study area.

• Journal of the Korean earth science society
• /
• v.28 no.2
• /
• pp.202-213
• /
• 2007

The Odaesan earthquake $(M_L=4.8)$ occurred near Mt. Odae, Jinbu-Myon, Pyongchang-Gun, Kangwon Province on January 20, 2007. It has a shallow focal depth about 10 km. Its felt area covers most of the southern peninsula except some southern and western inland area. The maximum MM intensity was VI in the areas including Jinbu, Doam, Kangreung, Jumunjin, and Pyongchang. In these areas, there was a very strong shaking that caused several cracks on the walls of buildings and houses, slates falling off the roof, tiles being off the wall, things falling off the desk, and rock falling from the mountains. In order to get fault plane solutions, grid searches were performed by fitting distributions of P-wave first-motion polarities and SH/P amplitude ratios for each event. The results showed that the main shock represented right-lateral strike-slip sense and two aftershocks, reverse sense. It seems that the seismogenic fault may be the NNE-SSW trending Weoljeongsa fault near the epicenter based on the distribution of epicenters (foreshock, main shock, and aftershocks), damage area, and fault plane solution. The distribution of the epicenters indicates that the length of the subsurface rupture is estimated to be about 2 km.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.35 no.3
• /
• pp.167-173
• /
• 2013

Purpose: The aim of this study is to analyze the series of panoramic radiograph of implant patients using the system to measure peri-implant crestal bone loss according to the elapsed time from fixture installation time to more than three years. Methods: Choose 10 patients having 45 implant fixtures installed, which have series of panoramic radiograph in the period to be analyzed by the system. Then, calculated the crestal bone depth and statistics and selected the implant in concerned by clicking the implant of image shown on the monitor by the implemented pattern recognition system. Then, the system recognized the x, y coordination of the implant and peri-implant alveolar crest, and calculated the distance between the approximated line of implant fixture and alveolar crest. By applying pattern recognition to periodic panoramic radiographs, we attained the results and made a comparison with the results of preceded articles concerning peri-implant marginal bone loss. Analyzing peri-implant crestal bone loss in a regression analysis periodic filmed panoramic radiograph, logarithmic approximation had highest $R^2$ value, and the equation is as shown below. $y=0.245Logx{\pm}0.42$, $R^2=0.53$, unit: month (x), mm (y) Results: Panoramic radiograph is a more wide-scoped view compared with the periapical radiograph in the same resolution. Therefore, there was not enough information in the radiograph in local area. Anterior portion of many radiographs was out of the focal trough and blurred precluding the accurate recognition by the system, and many implants were overlapped with the adjacent structures, in which the alveolar crest was impossible to find. Conclusion: Considering the earlier objective and error, we expect better results from an analysis of periapical radiograph than panoramic radiograph. Implementing additional function, we expect high extensibility of pattern recognition system as a diagnostic tool to evaluate implant-bone integration, calculate length from fixture to inferior alveolar nerve, and from fixture to base of the maxillary sinus.

• The Journal of Engineering Geology
• /
• v.6 no.3
• /
• pp.165-184
• /
• 1996

The earthquake(M=4.5 by KMA), which occurred in the northeastern part of Yeongweol($37^{\circ}$ 15.75' N, $128^{\circ}$ 42.13' E) on December 13, 1996, shows shallow focal depth(about 8.0km) and relatively large felt area covering most of the southern peninsula. This is the first medium-size earthquake in inland region of the southern peninsula since 1978. It did not trigger foreshock but 13 aftershocks($M{\;}{\geq}{\;}2.5$) for a month. The intensity based on the felt area estimation of about 400 places shows MIMI III-VII in inland region, II on Cheju Island and I on ulreung Island. The isoseismal of MIMI VII shows an elongated circle in the direction of NE-SW and covers some parts of Jungdong-myon, Yeongweol-kun, Sindong-eup and Nam-myun, Jeongseon-kun. There occurred quite strong shaking, numerous cracks on the walls of buildings, falling and movement of slate and tiles on the roofs, falling of tiles from the wall and falling of materials from desks, rock falling from mountain and collapse of gravel layers on the river side. Mainshock and aftershocks occurred condensely between Yemi and Hwaam areas. The felt area due to the Yeongweol earthquake is Quite larger than those of similar size earthquakes in the Korean Peninsula.

• Journal of Internet Computing and Services
• /
• v.15 no.2
• /
• pp.109-127
• /
• 2014

This study is devised out of the recognition that the existing standardization-related research has not sufficiently examined the overall social environment where a standard is actually made and diffused and the roles of the actors and the changes in them in the complex social system where multiple stakeholders exist. Against this backdrop, this study purports to reconstruct the dynamic process of developing and standardizing an innovative technology through a socio-technical approach involved by multiple stakeholders with different interests in the context of a socio-technical institutional environment. The specific goals to achieve the purpose include first, inspecting the characteristics of the interactions between the human actors and between the human and non-human actors in the socio-technical network surrounding a standardization process. Second, the study aimed to observe the activities of the focal actor who led the standardization process and its changing role. To that end, it analyzed the dynamic features of the process of standardizing a HD 3DTV broadcasting technology that took place in South Korea based on the actor network theory. As for the analysis method, the researchers personally took part in the actor network involving the new technology to analyze the dynamic characteristics of the network, applying the qualitative research method of survey and in-depth interviews and exploring the overall dynamics of environment, behavior and technology observed over the course of the entire standardization process.

• Journal of radiological science and technology
• /
• v.34 no.3
• /
• pp.203-208
• /
• 2011

In this study, we investigated factors for affecting pneumothorax in percutaneous needle aspiration biopsy of lung lesions. This research were conducted at University Hospital in Daejeon from August 2007 to May 2008. Total 104 patients between the ages of 25~85 who had focal lung lesions were grouped in terms of the tumor location, tumor size, depth of lesion, gender, age, biopsy time, and the number of biopsies. Then, their correlations with pneumothorax were studied. The incidence of pneumothorax according to the positions showed 27.3% in the right lower lobe, 24.3% in the right upper lobe, 15% in the left lower lobe and 12% in the left upper, respectively. In addition, the incidence by lesion size showed 24.0% in 0~2.0 cm, 18.2% in 2.1~4.0 cm, above 20.0% in 4.1 cm respectively. The probabilities of pneumothorax was 6.7% at 0 cm depth of lesion, 24.2% at 0.1~2.0 cm and greater than 26.8% at 2.1 cm. By gender differences, we found that probability of incidence of pneumothrax is 21.7% for male and 17.1% for female. According to age, pneumothorax occurred in 25% in the group of less than 40-years-old, 11.7% in 41~50 years, 14.3% in 51~60 years, 24.1% in 61~70 years old and 24.1% in over 70 years. According to the time of biopsy, the incidence of pneumothorax was 3.8% from 0 to 10.0 minutes, 18.9% from 10.1 to 20.0 minutes and 40% more than 21 minutes.

• Nuclear Medicine and Molecular Imaging
• /
• v.43 no.6
• /
• pp.557-564
• /
• 2009

Purpose: To evaluate the relationship between F-18 FDG uptake of tumor in PET/CT scan and pathological or immunohistochemial parameters of colorectal cancer. Materials and Methods: 147 colorectal cancer patients who underwent both pre-operative F-18 FDG PET/CT scan and surgery were included. In cases with perceptible FDG uptake in primary tumor, the maximum standardized uptake value (SUVmax) was calculated. The pathologic results such as site, size, depth of invasion (T stage), growth pattern, differentiation of primary tumor, lymph node metastasis and Dukes-Astler & Coller stage and immunohistochemical markers such as expression of EGFR, MLH1, MSH2 and Ki-67 index were reviewed. Results: 146 out of 147 PET/CT scans with colorectal cancer showed perceptible focal FDG uptake. SUVmax showed mild positive linear correlation with size of primary tumor (r=0.277, p=0.001) and Ki-67 index (r=0.226, p=0.019). No significant difference in F-18 FDG uptake was found according to site, depth of invasion (T stage), growth pattern, differentiation of primary tumor, presence of lymph node metastasis, Dukes-Astler & Coller stage and expression of EGFR. Conclusion: The degree of F-18 FDG uptake in colorectal cancer was associated with the size and the degree of Ki-67 index of primary tumor. It could be thought that FDG uptake of primary tumor has a correlation with macroscopic and microscopic tumor growth.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.17 no.6
• /
• pp.195-208
• /
• 2022

The role of venture CEO and their intrinsic capabilities on organizational performance can be determined by the level of resource synchronization initiated by the focal managers. Despite the important role of venture CEOs, a systematic lack of in-depth theoretical and empirical studies on ruminating the relationship between the effects of a CEO's capabilities and organizational performance depending on the level of resource synchronization exist for the rationale of investigation. To supplement the limitations of previous studies, this research empirically analyzes the role of managers specifically synchronizing organizational resources that affect organizational performance in the professional sports industry. Based on the entrepreneurship theory and resource-based view (RBV), this research conceptualizes the roles of venture CEO and basketball head coach in the professional sports industry as very similar in terms of organizational structure and performance mechanism embedding entrepreneurial characteristics necessary for managing organizational resources. In this research, we hypothesized (1) organizational resource synchronization will mediate the positive relationship between the ability of professional basketball head coach and organizational performance and (2) the indirect effect of the professional basketball head coach's capabilities on organizational performance mediated by resource synchronization will be moderated by the capabilities of players. To test these hypotheses, we utilized the PROCESS macro model 58 with the empirical data of 9 seasons (2013~2014-2021~2022) of 30 National Basketball Association (NBA) and 10 Korean Basketball League (KBL) teams. The statistical results showed that (1) resource synchronization mediates the positive relationship between professional basketball head coach capabilities and organizational performance and (2) the capabilities of players moderated the indirect effects of the abilities of head coaches on team performance via resource synchronization. This paper contributes to both academic and practical domains of entrepreneurship by empirically testing the research model through objective professional sports data.