• Science of Emotion and Sensibility
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• v.14 no.1
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• pp.157-164
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• 2011

Emotion science is one of the rapidly expanding engineering/scientific disciplines which has a major impact on human society. Such growing interests in emotion science and engineering owe the recent trend that various academic fields are being merged. In this paper we propose the potential importance of the biochip technology in which the human emotion can be precisely measured in real time using body fluids such as blood, saliva and sweat. We firstly and newly name such a biochip an Emotion-On-a-Chip (EOC). EOC consists of biological markers to measure the emotion, electrode to acquire the signal, transducer to transfer the signal and display to show the result. In particular, microfabrication techniques made it possible to construct nano/micron scale sensing parts/chips to accommodate the biological molecules to capture the emotional bio-markers and gave us a new opportunities to investigate the emotion precisely. Future developments in the EOC techniques will be able to help combine the social sciences and natural sciences, and consequently expand the scope of studies.

• Clinical and Experimental Reproductive Medicine
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• v.27 no.1
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• pp.1-7
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• 2000

Objective: Mammalian embryos undergo changes of energy environment for transfer from oviduct to uterus. Also, the human reproductive organ (oviduct, uterus) contains energy sources of different concentration (oviduct - glucose: 0.5 mM, pyruvate: 0.32 mM, lactate: 10.5 mM; uterus - goucose: 3.15 mM, pyruvate: 0.1mM, lactate: 5.87 mM, respectively). This study was conducted to examine the effect of these energy sources added in DMEM with glutamine on the mouse embryo development. Methods: There was used ICR female mouse. Two cell embryos of mouse are collected by method of 'flushing'. Flushing fluid was used Ham's F-10 added to 20% FBS. The collected 2 cell embryos were cultured in media such as Control (only DMEM), group A and B (DMEM supplemented with 0.5 mM and 3.15 mM glucose), and group C and D (DMEM supplemented with 0.1 mM and 0.32 mM pyruvate), and group E and F (DMEM supplemented with 5.87 mM and 10.5 mM lactate). All experimental media supplemented with 20% hFF, respectively. Pattern of embryo development was observed to interval at 24hr during 96hr. Results : The media with glutamine added glucose (group A: 51.0%; group B: 48.4%) was significantly (p<0.05) higher than other experimental group in development into the morula stage after 24 hr in culture, but not significantly different compared with control and the rate of development into the blastocyst was significantly (p<0.05) low in the both of pyruvate (group C: 7.9% group D: 6.8%) and lactate (group E: 7.1%, group F: 7.1%) treatment group after 48 hr in culture. Development into the blastocyst and hatched balstocyst after 72 hr in culture revealed similarly in control (81.9%) and glucose treatment group (group A: 83.3%, group B: 82.8%). However, development into the hatched and attached blastocyst after 96hr in culture revealed significantly (p<0.05) development in the glucose treatment group (group A: 82.3%, group B: 78.5%) than control (63.2%), and its of pyruvate (group C: 34.1%, group D: 34.1%) and lactate (group E: 25.9%, group F: 33.3%) treatment group were significantly (p<0.05) lower than control similar to previous observations. Conclusion : The glucose added to the DMEM with only glutamine, as energy source, was highly to the rate of development compared with control, but the other energy sources were not, synthetically. Above refer to, the human reproductive organ (oviduct, uterus) contains energy sources of different concentration. Thus, further studies are will examine continuously to effects by interaction of different energy sources in the mouse embryo development, and these results will provide to foundation on the human embryo culture.

• KIEE International Transaction on Systems and Control
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• v.2D no.2
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• pp.78-91
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• 2002

In the thermal power plant, there are six manipulated variables: main steam flow, feedwater flow, fuel flow, air flow, spray flow, and gas recirculation flow. There are five controlled variables: generator output, main steam pressure, main steam temperature, exhaust gas density, and reheater steam temperature. Therefore, the thermal power plant control system is a multinput and output system. In the control system, the main steam temperature is typically regulated by the fuel flow rate and the spray flow rate, and the reheater steam temperature is regulated by the gas recirculation flow rate. However, strict control of the steam temperature must be maintained to avoid thermal stress. Maintaining the steam temperature can be difficult due to heating value variation to the fuel source, time delay changes in the main steam temperature versus changes in fuel flow rate, difficulty of control of the main steam temperature control and the reheater steam temperature control system owing to the dynamic response characteristics of changes in steam temperature and the reheater steam temperature, and the fluctuation of inner fluid water and steam flow rates during the load-following operation. Up to the present time, the Proportional-Integral-Derivative Controller has been used to operate this system. However, it is very difficult to achieve an optimal PID gain with no experience, since the gain of the PID controller has to be manually tuned by trial and error. This paper focuses on the characteristic comparison of the PID controller and the modified 2-DOF PID Controller (Two-Degrees-Freedom Proportional-Integral-Derivative) on the DCS (Distributed Control System). The method is to design an optimal controller that can be operated on the thermal generating plant in Seoul, Korea. The modified 2-DOF PID controller is designed to enable parameters to fit into the thermal plant during disturbances. To attain an optimal control method, transfer function and operating data from start-up, running, and stop procedures of the thermal plant have been acquired. Through this research, the stable range of a 2-DOF parameter for only this system could be found for the start-up procedure and this parameter could be used for the tuning problem. Also, this paper addressed whether an intelligent tuning method based on immune network algorithms can be used effectively in tuning these controllers.

• Clinical and Experimental Reproductive Medicine
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• v.30 no.4
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• pp.333-340
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• 2003

Objective: This study was performed to examine the maturation and the development to the blastocyst stage of immature oocytes collected from patients with high risk of ovarian hyperstimulation syndrome (OHSS). Materials and Methods: Cumulus-oocyte complexes (COCs) were collected following only HCGpriming for non stimulated IVF-ET cycles of the patients. At the time of oocyte collection, COCs were classified into three groups in accordance with their appearance (Group I: oocytes with dispersed cumulus cells; Group II: oocytes with compacted cumulus cells; Group III: oocytes with sparse cumulus cells). The in vitro maturation and blastocyst development rates of the COCs were compared among these groups. From August 2001 to June 2002, 48 IVM/IVF-ET cycles from 42 patients (mean age: $32.4{\pm}3.8$ years) were performed. To prevent the occurrence of OHSS, the patients were primed with 10, 000 IU HCG alone 36 h before oocyte collection without gonadotropin stimulation. Oocytes were aspirated on cycle days from 7 to 13. The normal COCs were classified into three groups according to their appearance. The aspirated immature oocytes were cultured in YS maturation medium containing 30% (v/v) human follicular fluid (HFF), 1 IU/ml FSH, 10 IU/ml HCG and 10 ng/ml rhEGF. Fertilization was induced by intracytoplasmic sperm injection (ICSI). All zygotes were co-cultured with cumulus cells in $10{\mu}l$ YS medium containing 10% HFF until day 7 after oocyte collection. Blastocyst transfer was performed on day 5 after ICSI. Results: Th e mean number of oocytes cultured in the IVM/IVF cycles was $24.7{\pm}10.6$. Of 1185 COCs, those assigned to Group I, II and III were 470 (39.7%), 414 (35.0%) and 301 (25.4%), respectively. The maturation rate (94.5%, 444/470, p<0.05) in Group I was significantly higher than those of Group II (62.8%, 260/414) and Group III (73.1%, 220/301). Especially, 30.9% of COCs in Group I (145/470) was matured on the day of oocyte aspiration. There were no differences in the rates of fertilization and cleavage among the three groups. The development rate to the blastocyst stage in Group I (54.6%, 206/377, p<0.05) was also significantly higher than those in Group II (33.0%, 68/206) and Group III (30.1%, 52/173). Twenty-four clinical pregnancies (50.0%) was obtained and 22 pregnancies (45.8%) are ongoing. Implantation rate in the present study was 24.6%. Conclusion: These results suggest that there is a positive correlation between the appearance of COCs and the developmental competence of the immature oocytes in non stimulated IVM/IVF cycles.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.28-35
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• 2016

The in-situ thermal response test for the design of a ground heat exchanger of geothermal heat pumps have difficulty in predicting the outlet temperature according to the variation of conditions due to the expense and time. This paper suggests a 3-D CFD analysis method to predict the heat transfer performance of vertical type ground heat exchanger, which is mostly used in national, and the outlet temperature and the slope of two in-situ thermal response tests were compared to test the proposed CFD reliability. The results of CFD analysis showed that the outlet temperature was predicted to within $0.5^{\circ}C$ of the actual value and the slope was predicted to within 1.6%. The reliability of the CFD analysis method was confirmed using this process, and the outlet temperature prediction of the two in-situ thermal response tests was obtained by changing ${\pm}20%$ of the flow rate and the effective thermal conductivity conditions, respectively. The results of CFD analysis showed that the outlet temperature of Case 1 was 28.0 (-20%) and $29.6^{\circ}C$ (+20%) for the flow rate variation and $29.6^{\circ}C$ (-20%) and $28.0^{\circ}C$ (+20%) for the effective thermal conductivity variation, and the outlet temperature of Case 2 was 28.4 (-20%) and $29.8^{\circ}C$ (+20%) for the flow rate variation and $29.7^{\circ}C$(-20%) and $28.4^{\circ}C$(+20%) for the effective thermal conductivity variation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.251-259
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• 2016

This study examined the DO concentration distribution and ORP distribution using microbubbles on pilot-scale aeration tanks. As a result of MLSS mixing and oxygen transfer phenomenon using microbubbles, different DO concentrations were observed depending on the circulation of the liquid with the microbubble supply location on the lateral of an aeration tank. The simulation results of CFD (computational fluid dynamics) program showed that MLSS mixed with a microbubble supply in the middle the reactor is much better than on the left side of the reactor. A single reactor containing an anaerobic, anoxic, and aerobic zone, was evaluated without partition according to the location of the microbubble supply based on the experiments and CFD analysis. MLSS was separated into solid-liquid by the microbubble supply in the aeration tank. Consequently, selecting the appropriate microbubble size is important for MLSS mixing and was maintained at the proper DO concentration for biological treatment.

• Applied Chemistry for Engineering
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• v.32 no.6
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• pp.613-620
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• 2021

A flow channel shape of PEMFC has an influence on the internal flow uniformity. If the reactant distribution in a flow path is not uniform during operation, both catalyst deactivation and mechanical damage of membrane could occur resulting in decreasing the membrane electrode assembly (MEA) durability. Numerous studies concerning flow design have been conducted to make smooth supply and uniform distribution of reactants in fuel cells. The baffle of flow path could improve fuel cell performance through the forced convection effect. A sub-channel, as an additional air flow path, could increase the reactant concentration and reduce the mass transfer loss via a smooth water discharge. In this study, computational fluid dynamics (CFD) was used to analyze the effect of blocks and sub-channels on the current density and oxygen concentration of the fuel cell. As a result, the limit current density and oxygen concentration at a rear block increased when using blocks and sub-channels in a flow channel. In particular, the current density increased significantly when the sub-channel was placed between two blocks. Also, the sub-channel position was optimized by analyzing the oxygen concentration, and the oxygen concentration was recovered at a rear block in the fuel cell.

• Journal of the Korean Society for Geothermal and Hydrothermal Energy
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• v.19 no.2
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• pp.8-19
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• 2023

Hydronic heated road pavement (HHP) systems have well studied and documented by many researchers. However, most of the systems run on asphalt, only a few are tested with concrete, and there rarely is a comparison between those two common road materials in their heating and cooling performance. The aim of this study is to investigate the thermal performance of the HHP, such as heat dissipation performance in winter season while focusing on the surface temperature of the concrete and asphalt pavement. For preliminary study a small-scale experimental system was designed and installed to evaluate the heat transfer characteristics of the HHP in the test field. The system consists of concrete and asphalt slabs made of 1 m in width, 1 m in length, and 0.25 m in height. In two slabs, circulating water piping was embedded at a depth of 0.12 m at intervals of 0.16 m. Heating performance in winter season was tested with different inlet temperatures of 25℃, 30℃, 35℃ and 40℃ during the entire measurement period. The results indicated that concrete's heating performance is better than that of asphalt, showing higher surface temperatures for the whole experiment cases. However, the surface temperature of both concrete and asphalt pavement slabs remained above 0℃ for all experimental conditions. The heat dissipation performance of concrete and asphalt pavements was analyzed, and the heat dissipation of concrete pavement was greater than that of asphalt. In addition, the higher the set temperature of the circulating water, the higher the heat dissipation. On the other hand, the concrete pavement clearly showed a decrease in heat dissipation as the circulating water set temperature decreased, but the decrease was relatively small for the asphalt pavement. Based on this experiment, it is considered that a circulating water temperature of 20℃ or less is sufficient to prevent road ice. However, this needs to be verified by further experiments or computational fluid dynamic (CFD) analysis.

• Clean Technology
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• v.29 no.3
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• pp.185-192
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• 2023

This study was conducted to obtain basic process simulation data before conducting pyrolysis experiments for the development of a thermochemical conversion system by recirculation of heat carrier and gases thereby. In this study, polypropylene (PP) was used as a pyrolysis sample material as an alternative to waste plastics, and fluid sand was used as a heat transfer medium in the system. Manganese (Mn) was chosen as the catalyst for the pyrolysis experiment, and the catalyst pyrolysis was performed by impregnating it in the sand. The basic properties of PP were analyzed using a thermogravimetric analyzer (TGA), and liquid oil was generated through catalytic pyrolysis under a nitrogen atmosphere at 600℃. The carbon number distribution of the generated liquid oil was confirmed by GC/MS analysis. In this study, the effects of the presence and the amount of Mn loading on the yield of liquid oil and the distribution of hydrocarbons in the oil were investigated. When Mn/sand was used, the residue decreased and the oil yield increased compared to pyrolysis using sand alone. In addition, as the Mn loading increased, the ratio of C₆~C₉ range gasoline in the liquid oil gradually increased, and the distribution of diesel and heavy oil with more carbon atoms than C₁₀ in the oil decreased. In conclusion, it was found that using Mn as a catalyst and changing the amount of Mn could increase the yield of liquid oil and increase the gasoline ratio in the product.

• Journal of the Korean Institute of Gas
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• v.27 no.2
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• pp.79-85
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• 2023

Recently, in the semiconductor process, large companies are seeking process changes from memory semiconductors to the foundry due to the increase in demand due to the 4th industry. industry is expanding. The characteristics of special gases and precursors, which are raw materials used to produce these semiconductor chips, are toxic, pyrophoric, inflammable, and corrosive. These semiconductor raw materials are operated in a closed system and do not leak to the outside during normal times, but when leaked, they spread to the inside of the gas box, and when proper ventilation is not provided inside the gas box, they spread to the outside, causing fires, explosions, or toxic substances. It can lead to major accidents such as leakage. Recently, there have been cases of accidents in which hazardous materials leaked from the closed system of the semi conductor process and spread to the inside and outside of the gas box. . In this study, we propose preventive measures based on the case of an accident in which raw material leaked from the VCR fitting, which is the connection part of the semiconductor raw material transfer pipe, and spread to the outside of the gas box.