• 대한의용생체공학회:의공학회지
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• 제43권2호
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• pp.71-80
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• 2022

The interaction between dual-ligand decorated particle-based delivery system and target cell under shear flow is predicted using probability model developed. We assumed the two kinds of ligand are decorated on the surface of the particle with 10% length difference. Fixed with other biophysical parameters, a study on the particle-cell interaction for the different non-specific interaction parameter is performed. To induce the firm adhesion, short ligand-receptor should be engaged. Also, it is shown that the rational design of ligand-receptor interaction, including receptor number, specific interaction parameter, kinds of ligand-receptor, etc., should be considered.

• 한국정밀공학회지
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• 제18권9호
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• pp.192-203
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• 2001

The design of gate and runner(delivery system) is one of the most important subject in injection molding. Delivery system is a channel to flow the polymer melt from the injection molding machine to the mold cavities. Also, delivery system affect quality and productivity of the part. The synthesis of delivery system of injection molding has been done empirically, since it requires profound knowledge about the moldability and causal effects on the properties of the part, which are not available to designers through the current CAD systems. GATEWAY is a knowledge module which contains knowledge to permit non-experts as well as mold design experts to generate the acceptable geometries of gate and runner far injection molded parts. A knowledge-based CAD system is constructed by adding the knowledge module, GATEWAY, to an existing geometric modeler. A knowledge-based CAD system is a new tool which enables the concurrent design and CIM with integrated and balanced design decisions at the initial design of injection molding.

• 한국농공학회:학술대회논문집
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• 한국농공학회 2005년도 학술발표논문집
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• pp.534-539
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• 2005

The purpose of this study is the introduction of pollutant loads's estimation into Saemangeum watershed area with M.E.'s guidebook for TMDL and GIS tool. To estimate reliable pollutants loads, it is necessary to think about characteristic of removal, discharge and runoff as time series. In this study, it was calculated for generation loads which be came from pollutant source, discharge loads which be reduced in the treatment facilities and delivery loads which be considered the self purification parameter and delivery distance. To assess the delivery distance handily, it was particularly estimated using Arc-GIS. It was met with good results that delivery loads of BOD, T-N and T-P was reflected to seasonal precipitation. Lastly to verify the estimated pollutant loads, HSPF developed by USEPA was applied to it. It was showed a relativity of observed to simulated data for flow, Temperature, DO, BOD, $NO_3^--N$ TN and TP. Consequantly, this delivery loads can make full use of model input data for prediction of pollutant loads.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 춘계학술대회 논문집
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• pp.169-170
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• 2010

• Tuberculosis and Respiratory Diseases
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• 제82권1호
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• pp.86-87
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• 2019

• Journal of Pharmaceutical Investigation
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• 제25권1호
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• pp.55-62
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• 1995

W/O and O/W emulsions of tegafur (50 mg/5 ml/kg) were orally administered to rats to compare with their mesenteric lymphatic delivery effects. And also in order to demonstrate the lymph targeting associated to the oral route, it was deemed necessary to investigate the fate of solution after oral administration as a control. Lymph and plasma samples were periodically taken from each subject of mesenteric lymphatic duct cannulated rats. Then, lymph and plasma levels of tegafur and its active metabolite, 5-FU, were simultaneously observed. Also pharmacokinetic parameters were compared with each others. On the other hand, most previous studies of lymphatic transport have not addressed the question of whether an increase in mesenteric or thoracic lymph transport by the manipulation of a suspected variable was due to a selective delivery to the intestinal lymphatics or an overall increase availability. Therefore, based on a physiologically based pharmacokinetic model which represents the characteristics of lymphatic systems, we are also going to determine the contributions of mesenteric lymph transport versus thoracic lymph transport of tegafur reported in reference(13). In comparison with tegafur solution, AUC and mean residence time of plasma tegafur were significantly increased in W/O emulsion but significantly decreased in O/W emulsion. Lymph flow rates were similar in both solution and W/O emulsion but half in O/W emulsion. AUC of tegafur in mesenteric lymph and in plasma for W/O emulsion were 3.7 times and 2.9 times more than those for O/W emulsion, respectively. And AUC of 5-FU in thoracic lymph for W/O emulsion was 3.7 times more than that for O/W emulsion. These results suggested that lymphatic delivery or tegafur by W/O emulsion was more effective than that by on emulsion due to its differences or formation ability of chylomicrons.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
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• pp.808-811
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• 2006

The KOMPSAT-2 was developed by KARI and it was successfully launched from Plesetsk, Russia on 28th July 2006. The Korean government decided the commercialization of the KOMPSAT-2 image data and direct reception services worldwide. SPOT Image, based in Toulouse (France) was selected by KARI through an international open bidding as a foreign company for the KOMPSAT-2 image promotion over the entire world except the territory of Republic of Korea including the North Korea, the United States of America, UAE, Saudi Arabia, Kuwait, Qatar, Oman, Yemen, Egypt, Iran, Iraq, Jordan, Lebanon, and Syria. KAI (Korea Aerospace Industry Ltd.) is an engaged Korean company for this area. KARI has responsibility to operate the satellite, data acquisition, archiving for the worldwide commercialization. For the processing and delivery of the KOMPSAT-2 image data to the users of KAI and SPOT Image, KAI has the binding contract with KARI. So KAI has the responsibility for the commercial ground station operation such as user support, data processing, and the data delivery. The KOMPSAT-2 ground station is hosted in KARI, so KARI has developed the concept of KOCUST (KOMPSAT-2 Commercial User Support Team) jointly with KAI to support the data processing and delivery as KOMPSAT-2 developer and satellite operator. The main purpose of the KOCUST is to support the operational activities to provide the data and service quality to satisfy customers. KOCUST will be organized by the members of KARI and KAI together. KARI members will mainly take the role of KOCUST coordination, data processing and user support in a public sector. KAI members are going to take user desk, data validation and delivery et cetera, which are related with users. This paper describes a summarized concepts of KOCUST like organization, dedicated tasks of each part and work flow of daily operation.

• 대한기계학회논문집A
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• 제20권7호
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• pp.2257-2265
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• 1996

In the cold rolling mill, it is very important that a constrained static flow stress of rolled strip and rolling force calculation model be exactly considered to improve an prediction accuracy for rolling forces. Therefore, in this study, the values of the constrained static flow stress are used by deriving the regression equation which is a function of rolling conditions(FDT, CT) and chemical compositions(C, Si, Mn), previously applied by making the tables of yield strength for hot coils with size. And with the consideration that an elastic deformation part of an rolled strip appears at the entry and delivery side of the contacting area between the work roll and rolled strip is calculated. By applying these methods, the more accurate prediction for rolling force is obtained. As a results, the deviation of thickness is significantly reduced in the rolling direction.

• 한국정보과학회논문지:정보통신
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• 제41권4호
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• pp.167-176
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• 2014

본 논문은 이동 환경 위주의 미래 인터넷 환경을 위해 제안된 Mobile Oriented Future Internet (MOFI) 구조에 대하여 OpenFlow 기반 구현 이슈와 KOREN 실험망을 이용한 성능 분석을 논의한다. MOFI 구조는 호스트 식별자(host identifier)와 지역 위치자(local locator) 사용, 데이터 전달을 위한 Query 우선의 데이터 전달(Query-First Data Delivery), 식별자와 위치자간 분산형 매핑 시스템(Distributed Mapping System)을 특징으로 한다. 기존 MOFI 연구에서는 intra-domain 이동성 지원을 위해 6-to-4 터널링 기법 및 리눅스 플랫폼을 활용한 구현 방식을 제안하고 실험실 테스트베드에서 성능분석을 수행하였다. 한편, 본 논문에서는 inter-domain 이동성 지원을 위한 세부 절차를 논의하고 Click Modular Router와 OpenFlow 플랫폼을 활용한 MOFI 구현 방식을 제안한다. 나아가, 실제 KOREN 실험망을 활용한 성능 실험을 통해 MOFI 구조와 기존 이동성 제어 방식인 Proxy Mobile IP (PMIP) 기법을 비교한다. 실험 결과, 이동성 제어를 위한 시그널링 지연 시간 및 처리되는 메시지 수 측면에서 MOFI 구조가 기존 PMIP 이동성 제어 기법에 비하여 더 좋은 성능을 보이고 있음을 확인하였다.

• 한국산학기술학회논문지
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• 제15권8호
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• pp.5363-5368
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• 2014

본 논문은 소양호 유역을 대상으로 배수구역의 유달오염부하량을 산정하여 유황 및 계절변화에 따른 소양호 유역에 미치는 기여율을 평가 하였다. 유황변화에 따른 배수구역의 기여율을 보면 인북천 유역의 SS와 T-P 항목이 평수량 이상과 저수량 기간에서 46%와 51%의 기여율을 T-P는 평수량 49.5%, 저수량 기간은 48.5%의 기여율을 보였다. 다음으로 계절 변화에 따른 기여율을 관찰한 결과, 인북천 SS 항목이 전 계절 동안 39.6%에서 44.3%를 T-P는 53.8%로 다른 배수구역에 비하여 높은 기여율을 보였다. T-N은 전 계절에서 내린천 유역이 39.6%에서 44.3%의 기여율을 보였다. 전체적으로 인북천 유역의 SS와 T-P 항목, 내린천의 T-N이 소양호 유역의 오염물질 유출에 높은 기여율을 보였다.