• Journal of Institute of Control, Robotics and Systems
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• v.16 no.3
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• pp.305-312
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• 2010

The aim of this study is to find an analytic solution to the problem of determining the optimal capacity of a batch-storage network to meet demand for finished products in a system undergoing joint random variations of operating time and batch material loss. The superstructure of the plant considered here consists of a network of serially and/or parallel interlinked batch processes and storage units. The production processes transform a set of feedstock materials into another set of products with constant conversion factors. The final product demand flow is susceptible to joint random variations in the cycle time and batch size. The production processes have also joint random variations in cycle time and product quantity. The spoiled materials are treated through regeneration or waste disposal processes. The objective function of the optimization is minimizing the total cost, which is composed of setup and inventory holding costs as well as the capital costs of constructing processes and storage units. A novel production and inventory analysis the PSW (Periodic Square Wave) model, provides a judicious graphical method to find the upper and lower bounds of random flows. The advantage of this model is that it provides a set of simple analytic solutions while also maintaining a realistic description of the random material flows between processes and storage units; as a consequence of these analytic solutions, the computation burden is significantly reduced. The proposed method has the potential to rapidly provide very useful data on which to base investment decisions during the early plant design stage. It should be of particular use when these decisions must be made in a highly uncertain business environment.

• The KIPS Transactions:PartD
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• v.15D no.4
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• pp.495-504
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• 2008

Aspect Oriented Programming(AOP) is a relatively new programming paradigm and has properties that other programming paradigms don't have. This new programming paradigm provides new modularization of software systems by cross-cutting concerns. In this paper, we propose a regression test method for program evolution by AOP. By using JoinPoint, we can catch a pointcut-name which makes it possible to test the incorrect pointcut strength fault and the incorrect aspect precedence fault. Through extending proof rules to aspect, we can recognize failures to establish expected postconditions faults. We can also trace variables using set() and get() pointcut and test failures to preserve state invariant fault. Using control flow graph, we can test incorrect changes in control dependencies faults. In order to show the correctness of our proposed method, channel management system is implemented and tested by using proposed methods.

• Macromolecular Research
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• v.8 no.4
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• pp.179-185
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• 2000

Generally vascular grafts with a relatively large inner diameter (> 5 mm) have been successfully employed for replacement in the human body. However, the use of small diameter grafts is limited, because these grafts rapidly occlude due to the thrombosis. The ideal blood-contacting surface of a prosthesis would be an endothelial cell (EC) lining, because the confluent monolayer of healthy ECs that culture natural blood vessels represents the ideal nonthrombogenic surface. For vascular graft application, the stable EC adhesion on surface under How conditions is very important. In this study, the adhesive strength of ECs attached on polymer surfaces coated with collagen type IV (Col IV), fibronectin (Fn), laminin (Ln), and treated with corona was investigated onto polyurethane (PU) films. The EC-attached PU surfaces were mounted on parallel-plate flow chambers in a How system prepared for cell adhesiveness test. Three different shear stresses (100, 150, and 200 dyne/㎠) were applied to the How chambers and each shear stress was maintained for 120 min to investigate the effect of shear stress and surface treatment condition on the EC adhesion strength. It was observed that the EC adhesion strength on the surface-modified PU films was in the order of Ln≡Fn > Col IV > corona 》 control. More than 70% of the adhered cells were remained on surface-modified PU surface after applying the shear stress,200 dyne/㎠ for 2 hrs, whereas the cells were completely detached on the control PU surface within 10 min after applying the same shear stress. It seems that the type of adsorbed proteins and hydrophilicitv onto the PU surfaces play very important roles for cell adhesion strength.

• Transactions of the Korean Society of Automotive Engineers
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• v.24 no.5
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• pp.527-537
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• 2016

Recent automakers are trying to be more precise with the dimension check and moving parts to guarantee high quality and satisfy customer requirements. The aim of this paper is to investigate the design tolerance suitability of door operating mechanism linked arms, lever, and cam-shaft in a mobile air handling unit. These parts are complicated because doors, arms, lever and cam-shaft are connected nonlinearly in 3D. The current tolerance analysis method poses problems in design analysis because the moving doors are reasonably suitable for the AHU function. The 3-DCS analysis method provided useful results not only in establishing the inspection criteria for the quality control of products but also in enabling economical production. As a result, the vent door had $1.62^{\circ}{\sim}1.72^{\circ}$ and the defrost door had $0.84^{\circ}{\sim}0.9^{\circ}$ for the directly connected arms operating-type. For the lever connected arm operating-type, the foot door had $2.0^{\circ}{\sim}2.24^{\circ}$ tolerance, while the tolerance values satisfied the air flow volume distribution rate criteria in the AHU. Finally, the results have confirmed the design's tolerance suitability by using 3-DCS analysis at the early design stages. Reliability can be achieved by analyzing accumulated tolerance during the sub-parts assembly process and the moving mechanism linked especially by arms, lever, and cam-shaft.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1507-1515
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• 2006

Angelica gigantis (AG), Rehamaninae Radix(RR), Paenia japonica (PJ), and Polygoni multiflori Radix (PM) have been used as medicinal plants to tonify the blood. General function of the drugs have been known to nourish blood and control the heart and liver meridians. Recently, several studies have proposed mechanisms by which some oriental medicinal herbs work on the immune system. However, it is uncertain whether aqueous-extract of these drugs has immunomodulatory effect yet. In this study, I investigated the immune promotive effects of the water-extracted AG, RR, PJ and PM. The water-extracted AG, RR, PJ and PM inhibited NO production and iNOS expression in LPS stimulated RAW 264.7 macrophage cell line. Among these extracts, AG and PM induced expression of IL-2 and IFN${\gamma}$ in mouse spleen cells. In the flow cytometry analysis, PM-stimulated mouse spleen cells showed an increase in B-cell phenotype (CD45R/B220). The oral administration of Polygoni multiflori water-extracts to mice having S-180 abdominal dropsy cancer prolonged life-span more than control mice. These data suggest that among these extracts, PM has cellular and humoral immune-enhancement effect through IL-2 and IFN${\gamma}$ cytokine production, the regulation of NO production in macrophage cells and the B cell production in spleen cells.

• International Journal of Computer Science & Network Security
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• v.21 no.4
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• pp.255-263
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• 2021

Smart grid is a fully-automated, bi-directional, power transmission network based on the physical grid system, which combines sensor measurement, computer, information communication, and automatic control technology. Blockchain technology, with its security features, can be integrated with Smart Grids to provide secure and efficient power management and transmission. This paper dicusses the deployment of Blockchain technology in Smart Grid. It presents application areas and protocols in which blockchain can be applied to in securing smart grid. One application of each area is explored in detail, such as efficient peer-to-peer transaction, lower platform costs, faster processes, greater flexibility in power generation to transmission, distribution and power consumption in different energy storage systems, current barriers obstructing the implementation of blockchain applications with some level of maturity in financial services but concepts only in energy and other sectors. Wide range of energy applications suggesting a suitable blockchain architecture in smart grid operations, a sample block structure and the potential blockchain technicalities employed in it. Also, added with efficient data aggregation schemes based on the blockchain technology to overcome the challenges related to privacy and security in the smart grid. Later on, consensus algorithms and protocols are discussed. Monitoring of the usage and statistics of energy distribution systems that can also be used to remotely control energy flow to a particular area. Further, the discussion on the blockchain-based frameworks that helps in the diagnosis and maintenance of smart grid equipment. We have also discussed several commercial implementations of blockchain in the smart grid. Finally, various challenges have been discussed for integrating these technologies. Overall, it can be said at the present point in time that blockchain technology certainly shows a lot of potentials from a customer perspective too and should be further developed by market participants. The approaches seen thus far may have a disruptive effect in the future and might require additional regulatory intervention in an already tightly regulated energy market. If blockchains are to deliver benefits for consumers (whether as consumers or prosumers of energy), a strong focus on consumer issues will be needed.

• Journal of The Korea Institute of Healthcare Architecture
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• v.27 no.4
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• pp.7-14
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• 2021

Purpose: This study summarized architectural planning data for clinical practice spaces for CPX/OSCE and Simulation spaces, through analysis of domestic and foreign literature and a survey of domestic colleges of medicine. Methods: This study analyzed the architectural planning elements of the clinical practice spaces of the college of medicine, through a literature review on the clinical practice space and the survey of four recently established colleges of medicine. Results: ① It is desirable to plan the floor plan type for Simulation and CPX/OSCE spaces as a corridor-separated type that separates the circulations between students and staff (faculty). ② The simulation area arranges their practice rooms around the control space where the circulation of the staff is made. Conversely, it is desirable to arrange the CPX/OSCE rooms around the test waiting room where students enter. ③ It is desirable to separate access to the staff and students to allow student control, and to install various support spaces facing the staff corridor to secure the movement of equipment and the flow of evaluators. ④ In the simulation area, the equipment stored in the storage must be set in each room before the practice according to the setting of delivery or surgery like, and the equipment that has been removed must be back, so the circulation is short and does not intersect with the student circulations. ⑤ Debriefing rooms, seminar rooms, etc. are arranged in the staff area for review and discussion of clinical situations where practice and evaluation have been completed. Implications: It is important to configure an appropriate movement system and spatial zoning for each space for simulation and CPX/OSCE.

• Journal of The Korean Society of Agricultural Engineers
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• v.64 no.5
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• pp.9-16
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• 2022

Syngas, also known as synthesis gas, synthetic gas, or producer gas, is a combustible gas mixture generated when organic material (biomass) is heated in a gasifier with a limited airflow at a high temperature and elevated pressure. The present research was aimed at modifying the existing LPG engine generator for fully operated syngas. During this study, the designed gasifier-powered woodchip biomass was used for syngas production to generate power. A 6.0 kW LPG engine generator was modified and tested for operation on syngas. In the experiments, syngas and LPG fuels were tested as test fuels. For syngas production, 3 kg of dry woodchips were fed and burnt into the designed downdraft gasifier. The gasifier was connected to a blower coupled with a slider to help the air supply and control the ignition. The convection cooling system was connected to the syngas flow pipe for cooling the hot produce gas and filtering the impurities. For engine modification, a customized T-shaped flexible air/fuel mixture control device was designed for adjusting the correct stoichiometric air-fuel ratio ranging between 1:1.1 and 1.3 to match the combustion needs of the engine. The composition of produced syngas was analyzed using a gas analyzer and its composition was; 13~15 %, 10.2~13 %, 4.1~4.5 %, and 11.9~14.6 % for CO, H₂, CH₄, and CO₂ respectively with a heating value range of 4.12~5.01 MJ/Nm³. The maximum peak power output generated from syngas and LPG was recorded using a clamp-on power meter and found to be 3,689 watts and 5,001 watts, respectively. The results found from the experiment show that the LPG engine generator operated on syngas can be adopted with a de-ration rate of 73.78 % compared to its regular operating fuel.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.6
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• pp.48-56
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• 2008

This study provides to car driver with car exhaust gas and sensor information which are car trouble code in engine and many sensors when the car has some problems. This is to provide car manager with many information of car sensors when we go to vehicle maintenance. For example, information of engine RPM, fuel system, intake air temperature, air flow sensors and oxygen sensors can provide to owner or garage, and also add to multimedia system for mp3 files and video files. This system consists of embedded linux system of low power while driving the car which uses OBD-II protocols and zigbee communication interface from CAN communication of car system to self-diagnosis embedded system of car. Finally, low power embedded system has a lot of application and OBD-II protocols for embedded linux system and CAN communication which get sensor informations of car control sensor system while driving the car.

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.2
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• pp.76-83
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• 2006

Epidemiological studies have indicated that the ubiquitous consumption of seaweeds is a protective factor against some types of cancer. Previous results showed that the administration of seaweed powder or extract reduced the incidence rate of chemically induced tumorigenesis using in vivo animal model. Recently, we reported that the extracts of Gloiopeltis furcata, a kind of Korean edible seaweed, caused he cell growth inhibition of various human cancer cell lines, among them methanol extract exhibited a relatively strong antiproliferative activity. However, the molecular mechanisms of this seaweed in malignant cells have been poorly studied until now. To elucidate this problem, we investigated the effects of methanol extract of G. furcata (MEGF) on the growth inhibition in several human cancer cell lines, and further we analyzed the effects of this extract were tested on the activity of apoptosis induction in human leukemic cells. The results demonstrated that MEGF treatment resulted in the morphological changes and the growth inhibition in a dose-dependent manner. Furthermore, MEGF potently suppresses the growth of human leukemic U937 cells by induction of apoptosis, which was associated with induction of cyclin-dependent kinase inhibitor p21(WAF1/CIP1) in a tumor suppressor p53-independent fashion and up-regulation of Fas/FasL system. Further studies will be needed to identify the active compounds that confer the anticancer activity of MEGF. Once such compounds are identified, the mechanisms by which they exert their effects can begin to be characterized.