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Characteristics of Coagulase-negative Staphylococci Isolates from Dental Clinic Environments in Busan, Korea (부산지역 치과환경에서 분리된 coagulase-negative staphylococci의 특성)

  • Jung, Hye-In;Jung, So Young;Park, Indal;Bae, Il Kwon
    • Journal of Life Science
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    • v.26 no.2
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    • pp.220-225
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    • 2016
  • Coagulase-negative staphylococci (CNS) have recently become the bacteria most frequently found in clinical infections. The aim of this study was to investigate the prevalence, antimicrobial susceptibilities, and molecular characteristics of CNS isolates from dental clinic environments in Busan, Korea. One hundred and fifty-four samples were collected from 10 dental clinics and dental hospitals in Busan from December 2014 to January 2015. Species were identified by matrix-assisted laser desorption/ionization–time-of-flight. Antimicrobial susceptibility was determined by disk diffusion methods. A polymerase chain reaction was performed to detect mecA, mupA gene, and SCCmec types. Of the 154 samples, 10(6.5%) isolates were identified as CNS (5 Staphylococcus epidermidis, 2 Staphylococcus capitis, 2 Staphylococcus, and 1 Staphylococcus haemolyticus). Among the 10 isolates, 6 were resistant to penicillin, 5 were resistant to gentamicin, 3 were resistant to tetracycline, and 2 were resistant to cefoxitin and erythromycin. However, clindamycin, ciprofloxacin, teicoplanin, and trimethoprim-sulfamethoxazole resistant isolates were not present. Genes encoding mecA were detected in 4 (2 S. warneri and 2 S. haemolyticus) isolates, and mupA in 1 (S. epidermidis) isolate. One methicillin-resistant CNS (S. warneri) isolate was determined as being of the SCCmec type I. It is concluded that CNS resistant to various antimicrobial agents was widely distributed in dental clinic environments in Korea.

Characterization of Water Absorption by CFRP Using Air-Coupled Ultrasonic Testing (공기결합 초음파탐상에 의한 CFRP 복합재의 흡습 특성 평가)

  • Lee, Joo-Min;Lee, Joo-Sung;Kim, Yong-Kwon;Park, Ik-Keun
    • Journal of the Korean Society for Nondestructive Testing
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    • v.34 no.2
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    • pp.155-164
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    • 2014
  • Carbon-fiber-reinforced plastic (CFRP) composites are increasingly being used in a variety of industry applications, such as aircraft, automobiles, and ships because of their high specific stiffness and high specific strength. Aircraft are exposed to high temperatures and high humidity for a long duration during flights. CFRP materials of the aircraft can absorb water, which could decrease the adhesion strength of these materials and cause their volumes to change with variation in internal stress. Therefore, it is necessary to estimate the characteristics of CFRP composites under actual conditions from the viewpoint of aircraft safety. In this study air-coupled ultrasonic testing (ACUT) was applied to the evaluation of water absorption properties of CFRP composites. CFRP specimens were fabricated and immersed in distilled water at $75^{\circ}C$ for 30, 60, and 120 days, after which their ultrasonic images were obtained by ACUT. The water absorption properties were determined by quantitatively analyzing the changes in ultrasonic signals. Further, shear strength was applied to the specimens to verify the changes in their mechanical properties for water absorption.

Three body problem in early 20th century (20세기초의 삼체문제에 관해서)

  • Lee, Ho Joong
    • Journal for History of Mathematics
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    • v.25 no.4
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    • pp.53-67
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    • 2012
  • Today, it is necessary to calculate orbits with high accuracy in space flight. The key words of Poincar$\acute{e}$ in celestial mechanics are periodic solutions, invariant integrals, asymptotic solutions, characteristic exponents and the non existence of new single-valued integrals. Poincar$\acute{e}$ define an invariant integral of the system as the form which maintains a constant value at all time $t$, where the integration is taken over the arc of a curve and $Y_i$ are some functions of $x$, and extend 2 dimension and 3 dimension. Eigenvalues are classified as the form of trajectories, as corresponding to nodes, foci, saddle points and center. In periodic solutions, the stability of periodic solutions is dependent on the properties of their characteristic exponents. Poincar$\acute{e}$ called bifurcation that is the possibility of existence of chaotic orbit in planetary motion. Existence of near exceptional trajectories as Hadamard's accounts, says that there are probabilistic orbits. In this context we study the eigenvalue problem in early 20th century in three body problem by analyzing the works of Darwin, Bruns, Gyld$\acute{e}$n, Sundman, Hill, Lyapunov, Birkhoff, Painlev$\acute{e}$ and Hadamard.

Improvement of Altitude Measurement Algorithm Based on Accelerometer for Holding Drone's Altitude (드론의 고도 유지를 위한 가속도센서 기반 고도 측정 알고리즘 개선)

  • Kim, Deok Yeop;Yun, Bo Ram;Lee, Sunghee;Lee, Woo Jin
    • KIPS Transactions on Software and Data Engineering
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    • v.6 no.10
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    • pp.473-478
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    • 2017
  • Drones require altitude holding in order to achieve flight objectives. The altitude holding of the drone is to repeat the operation of raising or lowering the drone according to the altitude information being measured in real-time. When the drones are maintained altitude, the drone's altitude will continue to change due to external factors such as imbalance in thrust due to difference in motor speed or wind. Therefore, in order to maintain the altitude of drone, we have to exactly measure the continuously changing altitude of the drone. Generally, the acceleration sensor is used for measuring the height of the drones. In this method, there is a problem that the measured value due to the integration error accumulates, and the drone's vibration is recognized by the altitude change. To solve the difficulty of the altitude measurement, commercial drones and existing studies are used for altitude measurement together with acceleration sensors by adding other sensors. However, most of the additional sensors have a limitation on the measurement distance and when the sensors are used together, the calculation processing of the sensor values increases and the altitude measurement speed is delayed. Therefore, it is necessary to accurately measure the altitude of the drone without considering additional sensors or devices. In this paper, we propose a measurement algorithm that improves general altitude measurement method using acceleration sensor and show that accuracy of altitude holding and altitude measurement is improved as a result of applying this algorithm.

Obesity-Associated Metabolic Signatures Correlate to Clinical and Inflammatory Profiles of Asthma: A Pilot Study

  • Liu, Ying;Zheng, Jing;Zhang, Hong Ping;Zhang, Xin;Wang, Lei;Wood, Lisa;Wang, Gang
    • Allergy, Asthma & Immunology Research
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    • v.10 no.6
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    • pp.628-647
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    • 2018
  • Purpose: Obesity is associated with metabolic dysregulation, but the underlying metabolic signatures involving clinical and inflammatory profiles of obese asthma are largely unexplored. We aimed at identifying the metabolic signatures of obese asthma. Methods: Eligible subjects with obese (n = 11) and lean (n = 22) asthma underwent body composition and clinical assessment, sputum induction, and blood sampling. Sputum supernatant was assessed for interleukin $(IL)-1{\beta}$, -4, -5, -6, -13, and tumor necrosis factor $(TNF)-{\alpha}$, and serum was detected for leptin, adiponectin and C-reactive protein. Untargeted gas chromatography time-of-flight mass spectrometry (GC-TOF-MS)-based metabolic profiles in sputum, serum and peripheral blood monocular cells (PBMCs) were analyzed by orthogonal projections to latent structures-discriminate analysis (OPLS-DA) and pathway topology enrichment analysis. The differential metabolites were further validated by correlation analysis with body composition, and clinical and inflammatory profiles. Results: Body composition, asthma control, and the levels of $IL-1{\beta}$, -4, -13, leptin and adiponectin in obese asthmatics were significantly different from those in lean asthmatics. OPLS-DA analysis revealed 28 differential metabolites that distinguished obese from lean asthmatic subjects. The validation analysis identified 18 potential metabolic signatures (11 in sputum, 4 in serum and 2 in PBMCs) of obese asthmatics. Pathway topology enrichment analysis revealed that cyanoamino acid metabolism, caffeine metabolism, alanine, aspartate and glutamate metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, pentose phosphate pathway in sputum, and glyoxylate and dicarboxylate metabolism, glycerolipid metabolism and pentose phosphate pathway in serum are suggested to be significant pathways related to obese asthma. Conclusions: GC-TOF-MS-based metabolomics indicates obese asthma is characterized by a metabolic profile different from lean asthma. The potential metabolic signatures indicated novel immune-metabolic mechanisms in obese asthma with providing more phenotypic and therapeutic implications, which needs further replication and validation.

The Study on Improvement about Structural Integrity of Main Landing Gear for Rotorcraft (회전익 항공기 구조건전성 향상을 위한 주륜착륙장치 결함 개선연구)

  • Jang, Min-Uk;Lee, Yoon-Woo;Seo, Young-Jin;Ji, Sang-Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.10
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    • pp.459-467
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    • 2019
  • The landing gear is a component that requires a high degree of safety to protect the lives of rotary-wing aircraft and boarding personnel, absorbing the impact on transfer/landing and supporting the fuselage during taxiing and mooring on the ground. In particular, the wheel landing gear supporting the aircraft fuselage absorbs most of the shock from the ground through the shock absorber and tires. This ensures the safety of the pilot on board the aircraft and satisfies the operational capability of the soldiers between missions. During the operation of a rotary-wing aircraft, a number of piston pins, which are a component of the right main wheel landing gear, were found to be broken. Therefore, this study examined the root cause of the piston pin crack phenomenon found in the main wheel landing gear. For this purpose, various causes were identified from fracture surface analysis of a flight test. In particular, the possibility of cracking was analyzed based on the influence on the fastening torque with the drag beam component applied to the piston pin at the time of development. This ensures the fatigue life and structural integrity.

Auto-Tracking Camera Gimbal for Power Line Inspection Drone and its Field Tests on 154 kV Transmission Lines (송전선로 자동추적 카메라 짐벌 및 154 kV 송전선로 현장시험)

  • Kim, Seok-Tae;Park, Joon-Young;Lee, Jae-Kyung;Ham, Ji-Wan
    • KEPCO Journal on Electric Power and Energy
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    • v.5 no.3
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    • pp.149-156
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    • 2019
  • In the field of maintenance of power transmission lines, drones have been used for their patrol and inspection by KEPCO since 2017. This drone technology was originally developed by KEPCO Research Institute, and now workers from four regional offices of KEPCO have directly applied this technology to the drone patrol and inspection tasks. In the drone inspection system, a drone with an optical zooming camera and a thermal camera can fly automatically along the transmission lines by the ground control system developed by KEPCO Research Institute, but its camera gimbal has been remotely controlled by a field worker. Especially the drone patrol and inspection has been mainly applied for the transmission lines in the inaccessible areas such as regions with river-crossings, sea-crossings and mountains. There are often communication disruptions between the drone and its remote controller in such extreme fields of mountain areas with many barriers. This problem may cause the camera gimbal be out of control, even though the inspection drone flies along the flight path well. In addition, interference with the reception of real-time transmitted videos makes the field worker unable to operate it. To solve these problems, we have developed the auto-tracking camera gimbal system with deep learning method. The camera gimbal can track the transmission line automatically, even when the transmitted video on a remote controller is intermittently unavailable. To show the effectiveness of our camera gimbal system, its field test results will be presented in this paper.

Optimization of Agri-Food Supply Chain in a Sustainable Way Using Simulation Modeling

  • Vostriakova, Viktorija;Kononova, Oleksandra;Kravchenko, Sergey;Ruzhytskyi, Andriy;Sereda, Nataliia
    • International Journal of Computer Science & Network Security
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    • v.21 no.3
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    • pp.245-256
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    • 2021
  • Poor logistical infrastructure and agri-food supply chain management leads to significant food waste in logistic system. The concept of the sustainable value added agri-food chains requires defined approach to the analysis of the existing situation, possible improving strategies and also assessment of these changes impact on further development. The purpose of research is to provide scientific substantiation of theoretical and methodological principles and develop practical recommendations for the improvement of the agri-food logistics distribution system. A case study methodology is used in this article. The research framework is based on 4 steps: Value Stream Mapping (VSM), Gap and Process Analysis, Validation and Improvement Areas Definition and Imitation Modelling. This paper presents the appropriateness of LEAN logistics tools using, in particular, Value Stream Mapping (VSM) for minimizing logistic losses and Simulation Modeling of possible logistics distribution system improvement results. The algorithm of VSM analysis of the agri-food supply chain, which involves its optimization by implementing the principles of sustainable development at each stage, is proposed. The methodical approach to the analysis of possible ways for optimizing the operation of the logistics system of the agri-food distribution is developed. It involves the application of Value Stream Mapping, i.e. designing of stream maps of the creation of the added value in the agri-food supply chain for the current and future state based on the minimization of logistic losses. Simulation modeling of the investment project on time optimization in the agri-food supply chain and economic effect of proposed improvements in logistics product distribution system functioning at the level of the investigated agricultural enterprise has been determined. Improvement of logistics planning and coordination of operations in the supply chain and the innovative pre-cooling system proposed to be introduced have a 3-year payback period and almost 75-80% probability. Based on the conducted VSM analysis of losses in the agri-food supply chain, there have been determined the main points, where it is advisable to conduct optimization changes for the achievement of positive results and the significant economic effect from the proposed measures has been confirmed. In further studies, it is recommended to focus on identifying the synergistic effect of the agri-food supply chain optimization on the basis of sustainable development.

Obtaining Informed Consent Using Patient Specific 3D Printing Cerebral Aneurysm Model

  • Kim, Pil Soo;Choi, Chang Hwa;Han, In Ho;Lee, Jung Hwan;Choi, Hyuk Jin;Lee, Jae Il
    • Journal of Korean Neurosurgical Society
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    • v.62 no.4
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    • pp.398-404
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    • 2019
  • Objective : Recently, three-dimensional (3D) printed models of the intracranial vascular have served as useful tools in simulation and training for cerebral aneurysm clipping surgery. Precise and realistic 3D printed aneurysm models may improve patients' understanding of the 3D cerebral aneurysm structure. Therefore, we created patient-specific 3D printed aneurysm models as an educational and clinical tool for patients undergoing aneurysm clipping surgery. Herein, we describe how these 3D models can be created and the effects of applying them for patient education purpose. Methods : Twenty patients with unruptured intracranial aneurysm were randomly divided into two groups. We explained and received informed consent from patients in whom 3D printed models-(group I) or computed tomography angiography-(group II) was used to explain aneurysm clipping surgery. The 3D printed intracranial aneurysm models were created based on time-of-flight magnetic resonance angiography using a 3D printer with acrylonitrile-butadiene-styrene resin as the model material. After describing the model to the patients, they completed a questionnaire about their understanding and satisfaction with aneurysm clipping surgery. Results : The 3D printed models were successfully made, and they precisely replicated the actual intracranial aneurysm structure of the corresponding patients. The use of the 3D model was associated with a higher understanding and satisfaction of preoperative patient education and consultation. On a 5-point Likert scale, the average level of understanding was scored as 4.7 (range, 3.0-5.0) in group I. In group II, the average response was 2.5 (range, 2.0-3.0). Conclusion : The 3D printed models were accurate and useful for understanding the intracranial aneurysm structure. In this study, 3D printed intracranial aneurysm models were proven to be helpful in preoperative patient consultation.

Analysis and Estimation of Food and Beverage Sales at Incheon Int'l Airport by ARIMA-Intervention Time Series Model (ARIMA-Intervention 시계열 모형을 이용한 인천국제공항 식음료 매출 분석 및 추정 연구)

  • Yoon, Han-Young;Park, Sung-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.458-468
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    • 2019
  • This research attempted to estimate monthly sales of food and beverage at the passenger terminal of Incheon int'l airport from June of 2015 to December 2020. This paper used ARIMA-Intervention model which can estimate the change of the sales amount suggesting the predicted monthly food and beverage sales revenue. The intervention variable was travel-ban policy against south Korea from P.R. China since July 2016 to December 2017 due to THAAD in south Korea. According to ARIMA, it was found normal predicted sales amount showed the slow growth increase rate until 2020 due to the effect of intervened variable. However, the monthly food sales in July and August 2019 was 20.3 and 21.2 billion KRW respectively. Each amount would increase even more in 2020 and the amount would increase to 21.4 and 22.1 billion KRW. The sales amount in 2019 would be 7.7 and 8.1 billion KRW and climb up 7.9 and 8.2 billion KRW in 2020. It was expected LCC passengers tend to spend more money for F&B at airport due to no meal or drink service of LCC or the paid-in meal and beverage service of LCC. The growth of sales of food and beverate will be accompanied with the growth of LCC according to estimated data.