• Title/Summary/Keyword: Fixed-Effects Model

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The Study on the Effect of Basic Pension on Subjective Well-being of the Elderly (기초연금 수급이 고령자의 주관적 삶의 질에 미치는 영향)

  • Kim, Hyeyoun
    • 한국노년학
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    • v.40 no.1
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    • pp.1-21
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    • 2020
  • The purpose of this study is to examine that basic pension entitlement affects the subjective well-being(SWB) of the elderly. For controlling unobserved heterogeneity, we used fixed effects model for longitudinal data. The data used for this study is KLoSA from 2006 to 2016. The research results are as follows. SWB of non-basic pensioners was higher than for basic pension beneficiaries. Second, when the demographic variables were controlled, SWB of the basic pension recipients was higher then that of non-beneficiaries. Third, the factors affecting SWB were economic satisfaction, marital status, family financial support, employment status, subjective health status, daily life restrictions, gender, and age. Fourth, the effect of basic pension on SWB was positive at the lowest income quartile. The results of this study shows that the basic pension system has a positive effect on the SWB of elderly despite the low benefit level. Therefore, it is necessary to expand the basic pension system to solve poverty problems and improve the quality of life for the aged. Also, various aspects of social support for the low-income vulnerable elderly are needed. Lastly, It was suggested that the benefit level of the basic pension should be raised to have a substantial effect on the low-income class, which is a key policy subject.

Effects of Olanzapine on the Schedule-Induced Polydipsic Rats (Olanzapine이 백서의 Schedule-Induced Polydipsia에 미치는 영향)

  • Lee, Gi-Chul;Lee, Kyung-Kyu;Chang, Hwan-Il;Lee, Jung-Ho;Kim, Hyun-Woo;Ha, Jun-Myung;Jeong, Jae-Hyun;Jeong, Hong-Kyung
    • Korean Journal of Biological Psychiatry
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    • v.6 no.2
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    • pp.240-245
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    • 1999
  • Object : This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as a serotonin and dopamine blocking agent, fluoxetine as a selective serotonin reuptake inhibitor, and haloperidol for the dopamine antagonist to rats which showed schedule-induced polydipsic behavior. Methods : Spraque-Dawley rats weighing 200-250gm were individually housed and maintained and allowed free access to water. The rats were placed on a restricted diet. To induce polydipsia, rats were placed in the cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT-60s) feeding schedule over 150 minute test session per day. Water was available at all times in the cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 5 groups of rats were administered olanzapine(3mg/kg, i.p), olanzapine(10mg/kg, i.p), fluoxetine(5mg/kg, i.p.), haloperidol(0.1mg/kg, i.p.), and vehicle(1cc/kg, i.p.) for 3 weeks. The rats were tested once a week to access schedule induced polydipsic behavior. Water bottles were weighed before and after the 150-minute test session. The chronic effects of administration of experimental drugs on schedule induced polydipsic behavior were analyzed with ANOVA and Scheffe test as a posthoc comparison. In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5gm) of food per day which maintained them at their average body weight. Results and Conclusion : The results were as follows ; 1) After 4 weeks of scheduled feeding procedure, the experimental group showed significant differences than the bolus control in the amount of water consumption as compared with their average water intakes for 4 weeks. At the same periods, there were no differences between the experimental group and the bolus control in the body weight. 2) The fluoxetine group showed significant decrease in the amount of water intake over the 3 weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 3mg group showed significant decrease in the amount of water intake at 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 10mg group showed significant decrease in the amount of water intake at 2nd and 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. However, the haloperidol group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their average amount of polydipsic water intakes. 3) The fluoxetine group showed significantly lower amounts of water intake than the haloperidol group at 2nd weeks of drug treatment. And also the fluoxetine group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. The olanzapine 3mg group and the olanzapine 10mg group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The authors assume that the serotonin hypothesis and the serotonin-dopamine interaction hypothesis are preferred to the dopamine hypothesis in the biological etiology of obsessive-compulsive disorder.

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The Effect of Coal Particle Size on Char-$CO_{2}$ Gasification Reactivity by Gas Analysis (가스분석을 이용한 석탄 입자크기가 촤-$CO_{2}$ 가스화 반응성에 미치는 영향 연구)

  • Kim, Yong-Tack;Seo, Dong-Kyun;Hwang, Jung-Ho
    • Korean Chemical Engineering Research
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    • v.49 no.3
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    • pp.372-380
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    • 2011
  • Char gasification is affected by operating conditions such as reaction temperature, reactants gas partial pressure, total system pressure and particle size in addition to chemical composition and physical structure of char. The aim of the present work was to characterize the effect of coal particle size on $CO_{2}$ gasification of chars prepared from two different types of bituminous coals at different reaction temperatures(1,000-$1,400{^{\circ}C}$). Lab scale experiments were carried out at atmospheric pressure in a fixed reactor where heat was supplied into a sample of char particles. When a flow of $CO_{2}$(40 vol%) was delivered into the reactor, the char reacted with $CO_{2}$ and was transformed into CO. Carbon conversion of the char was measured using a real time gas analyzer having NDIR CO/$CO_{2}$ sensor. The results showed that the gasification reactivity increased as the particle size decreased for a given temperature. The sensitivity of the reactivity to particle size became higher as the temperature increases. The size effects became remarkably prominent at higher temperatures and became a little prominent for lower reactivity coal. The particle size and coal type also affected reaction models. The shrinking core model described better for lower reactivity coal, whereas the volume reaction model described better for higher reactivity coal.

An Study on Long Run Effects of Determinants on Export of Korean Goods to US (한국의 대미국 수출 결정요인의 장기적 영향에 관한 연구)

  • Choi, Mun Seong
    • International Commerce and Information Review
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    • v.16 no.5
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    • pp.409-433
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    • 2014
  • In this paper, I estimate long-run elasticities of US real GDP and real exchange rate between Korean Won and US Dollar on export of Korean goods to US and analyze changes in their trend by using VECM and rolling regression with a fixed window. For the purposes I use the year data from 1990 to 2013 which are selected from UNCTAD, Korea Trade Association(KTA), and Bank of Korea(BOK). The results are that the long-run elasticities of US real GDP vary from 2.849 to 2.938 for the period from 1990 to 2013 depending on the models in VECM and all of them are significant statistically. The elasticities of real exchange rate between Korean WON and US Dollar vary from 0.962 to 0.967 for the same period depending on the models in VECM and all of them are significant statistically. In case of the results through the OLS and the rolling regression, the long-run elasticities of US. real GDP are 3.015 for Basic Model, 2.949 for the modified Model 1, and 2.125 for the modified Model 2 for the period from 1990 to 2013 depending on the models and all of them are significant statistically. The average of long-run elasticities of real US GDP before the global financial crisis of 2008 is greater than that after the global financial crisis of 2008. On the other hand, the long-run elasticities of real exchange rate between Korean WON and US $ are 0.347 for Basic Model, 0.566 for the modified Model 1, and -0.217 for the modified Model 2 for the same period and all of them are significant statistically except for the modified Model 2. The average of long-run elasticities of real exchange rate before the global financial crisis of 2008 is greater than that after the global financial crisis of 2008.

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HISTOLOGIC CHANGE OF THE POSTERIOR ATTACHMENT IN ANTERIOR DISC DISPLACEMENT OF THE TEMPOROMANDIBULAR JOINT-A NEW MODEL OF INTERNAL DERANGEMENT IN RABBITS (실험가토의 악관절원판 변위시 후방부착조직의 변화)

  • Kim, Tae-Woo;Ko, Jea-Seung;Chang, Young-il
    • The korean journal of orthodontics
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    • v.23 no.4 s.43
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    • pp.503-527
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    • 1993
  • This paper describes a new method to create an animal model for TMJ internal derangement in the New Zealand white rabbits and the light and electron microscopical changes of posterior attachment of them. Twenty six rabbits(2.5-3.0kg), four normal and twenty two experimental, were used. The right disc of experimental animal was displaced anteriorly without sectioning the posterior attachment and tied to the zygomatic arch with nylon not to be reduced to the original position. The left TMJ was sham-operated to be compared with its right experimental one. Normal animals were sacrificed one day and eight weeks after experiment. Experimental animals were sacrificed one day, ten days, three weeks, five weeks and eight weeks after surgery respectively. They were fixed intravenously with $2\%$ glutaldehyde under general anesthesia and the samples of them were processed for light and electron microscopic examination. The purpose of this experiment is to make a suitable animal model of disc displacement without reduction for studying and understanding the cellular and morphologic events in posterior attachment of TMJ including early changes which were difficult to be observed in human TMJs. The results of this investigation suggest the following conclusions : 1. Authors induced anterior disc displacement surgically in rabbits with new method to examine histologic changes of posterior attachment. Tissue reactions of this model seem to be similar to those observed in human disc displacement. We think this animal model for anterior disc displacement may be used to explore and evaluate objectively the effects of many treatment modalities in disc displacements. 2. The animal disease model showed inflammation at early stage(one and ten days). At this stage there were mild-to-severe mononuclear inflammatory cell infiltration, numerous newly formed vessels, vessel dilatation and engormement and many fibroblasts. 3. At middle stage(three weeks), fibrosis occurred, where fibroblasts decreased in number, but their cytoplasm was profuse indicating high activity. Collagen fibers increased in number and the tissue looked more dense. 4. At late stage(five weeks and eight weeks) showed degenerative changes including perforation of posterior attachment, disintegration of collagen fiber bundles, degeneration of fibroblasts, metastatic ossification, and dystrophic calcification.

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Genetic Evaluation and Calculating Daughter Yield Deviation of Bulls in Iranian Holstein Cattle for Milk and Fat Yields

  • Sheikhloo, M.;Shodja, J.;Pirany, N.;Alijani, S.;Sayadnejad, M.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.5
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    • pp.611-617
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    • 2009
  • This study was aimed at a genetic evaluation of Iranian Holstein cattle for milk and fat yields and calculating daughter yield deviation (DYD) of bulls. The data file that was used in this research included 367,943 first three lactation records of 186,064 Holstein cows which calved between 1983 and 2006 in 11,806 herd-year-season groups. The model included herd-year-season of calving and age at calving as fixed effects and animal and permanent environment as random effects. Mean breeding values of cows for each year were regressed on birth year to estimate genetic trends. Genetic trends in milk and fat yields were greater for cows born after 1997 (59.38 kg/yr and 1.11 kg/yr for milk yield and fat yield, respectively). Animal evaluations were partitioned into contribution from parent average, yield deviation (YD) and progeny. DYD of bulls was calculated as described by VanRaden and Wiggans (1991). DYD provides an indication of the performance of the daughters of a bull without consideration of his parents or sons. Variance of bull DYD was greater than variance of their predicted transmitting ability (PTA). Correlation of bull DYD and PTA was dependent on the number of daughters and when this increased, the correlation of DYD and PTA was increased. Also as lactation number of daughters increased, the correlation of bull DYD and PTA was increased.

Somatic Cells Count and Its Genetic Association with Milk Yield in Dairy Cattle Raised under Thai Tropical Environmental Conditions

  • Jattawa, D.;Koonawootrittriron, S.;Elzo, M.A.;Suwanasopee, T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.9
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    • pp.1216-1222
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    • 2012
  • Somatic cells count (SCC), milk yield (MY) and pedigree information of 2,791 first lactation cows that calved between 1990 and 2010 on 259 Thai farms were used to estimate genetic parameters and trends for SCC and its genetic association with MY. The SCC were log-transformed (lnSCC) to make them normally distributed. An average information-restricted maximum likelihood procedure was used to estimate variance components. A bivariate animal model that considered herd-yr-season, calving age, and regression additive genetic group as fixed effects, and animal and residual as random effects was used for genetic evaluation. Heritability estimates were 0.12 (SE = 0.19) for lnSCC, and 0.31 (SE = 0.06) for MY. The genetic correlation estimate between lnSCC and MY was 0.26 (SE = 0.59). Mean yearly estimated breeding values during the last 20 years increased for SCC (49.02 cells/ml/yr, SE = 26.81 cells/ml/yr; p = 0.08), but not for MY (0.37 kg/yr, SE = 0.87 kg/yr; p = 0.68). Sire average breeding values for SCC and MY were higher than those of cows and dams (p<0.01). Heritability estimates for lnSCC and MY and their low but positive genetic correlation suggested that selection for low SCC may be feasible in this population as it is in other populations of dairy cows. Thus, selection for high MY and low SCC should be encouraged in Thai dairy improvement programs to increase profitability by improving both cow health and milk yield.

Current Evidence on the Relationship Between Two Polymorphisms in the NBS1 Gene and Breast Cancer Risk: a Meta-analysis

  • Zhang, Zhi-Hua;Yang, Lin-Sheng;Huang, Fen;Hao, Jia-Hu;Su, Pu-Yu;Sun, Ye-Huan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5375-5379
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    • 2012
  • Introduction: Published studies on the association between Nijmegen breakage syndrome 1(NBS1) gene polymorphisms and breast cancer risk have been inconclusive, and a meta-analysis was therefore performed for clarification. Methods: Eligible articles were identified by a search of MEDLINE and EMBASE bibliographic databases for the period up to March 2012. The presence of between-study heterogeneity was investigated using the chi-square-based Cochran's Q statistic test. When there was statistical heterogeneity, the random effects model was chosen; otherwise, fixed effects estimates were reported as an alternative approach. Results: A total of 11 eligible articles (14 case-control studies) were identified, nine case-control studies were for the 657del5 mutation (7,534 breast cancer cases, 14,034 controls) and five case-control studies were for the I171V mutation (3,273 breast cancer cases, 4,004 controls). Our analysis results indicated that the 657del5 mutation was associated with breast cancer risk (carriers vs. non-carriers: pooled OR =2.63, 95% CI: 1.76-3.93), whereas the I171V mutation was not (carriers vs. non-carriers: pooled OR =1.52, 95% CI: 0.70-3.28). Conclusion: The present meta-analysis suggests that the 657del5 gene mutation in the NBS1 gene plays a role in breast cancer risk, while the I171V mutation does not exert a significant influence.

Investigation of Electromagnetic Force for Magnetic Contactor of Railway Vehicles (철도차량용 전자접촉기 전자코일의 전자기력 특성 연구)

  • Jung, Jooyoung;Park, Ji-Won;Choi, Jinnil
    • Journal of the Korean Society for Railway
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    • v.19 no.3
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    • pp.324-330
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    • 2016
  • A magnetic contactor is a switching device widely used for electric circuits. For the operation of magnetic contactors, magnetic coils are essential; these coils create and interrupt the electric circuit. In this paper, the finite element analysis model was developed to reflect the experimental data, and was verified through alteration of the applied voltages and the numbers of turns. Effects of electromagnetic force on the geometrical variations of the facing poles for fixed and moving cores of two magnet coils were investigated. In addition, effects of slope and air gap size between two facing poles on the electromagnetic force were explored through the distribution of the magnetic flux density in the magnetic coils of a push-type solenoid. Through this analysis, the characteristics of the electromagnetic force against the facing poles were explored.

Analysis on the Effects of Interference from HAPS Ground Stations to P-MP FWA System (HAPS 지상국에서 P-MP FWA 시스템으로의 간섭 영향 분석)

  • Ham Hyung-Il;Kang Young-Heung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.2 s.105
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    • pp.152-157
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    • 2006
  • In this paper, we have analyzed the effects of interference from HAPS ground stations to P-MP FWA base station and to P-MP FWA terminal station using more detail parameters such as a new interference model, a realistic HAPS scenario, practical antenna patterns for both the HAPS system and FWA systems. The analysis results show that, in the case of interference from HAPS GSs into a P-MP BS, compatibility of the two systems can be obtained by using a sectored BS antenna with the boresight directed away from the nadir. However, in the case of interference from HAPS GSs into a P-MP TS, the two systems cannot operate effectively in the same band unless the separation distance is guranteed and/or some form of interference mitigation technique is employed such as dynamic channel allocation.