• Title/Summary/Keyword: Fibrous

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A CLINICOPATHOLOGIC STUDY ON FIBROUS DYSPLASIA OF THE MAXILLOFACIAL REGIONS (악안면 부위에 발생한 섬유성 골이형성증에 대한 임상조직병리학적 연구)

  • PYO, Sung-Woon;Nam, Il-Woo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.14 no.1_2
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    • pp.124-134
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    • 1992
  • Fibrous dysplasia is a benign pathologic condition of bone in which fibrous tissue gradually expands and replaces normal bone into fibro-osseous lesion. It is a primary developmental abnormality of bone-forming mesenchyme in origin. This study shows clinical history, radiological and histopathological feature of fibrous dysplasia with the intention of establishing correct diagnosis, treatment plan and evaluation of prognosis. This paper reviews and summarizes the materials from 57 fibrous dysplasias submitted to the Department of Oral and Maxillofacial Surgery in College of Dentistry, Seoul National University. Conclusions obtained were as following : 1. Fibrous dysplasia developed mainly in teenagers and shows female predeliction. 2. Fibrous dysplasia developed much on the maxilla 3. Monostotic fibrous dysplasia was most popular form. 4. Main symptom of fibrous dysplasia was painless swelling. 5. Radiological feature of fibrous dysplasia was ground-glass appearance, 6. Histopathological feature of fibrous dysplasia was irregular immature bony trabeculae(woven bone). 7. Treatment of fibrous dysplasia was mainly conservative contouring surgery.

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A Case of Malignant Fibrous Histiocytoma of Trachea (기관에 발생한 악성 섬유성 조직구종 1례)

  • 이석기;김경봉;임길채;김상윤
    • Korean Journal of Bronchoesophagology
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    • v.7 no.1
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    • pp.46-49
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    • 2001
  • Fibrous histiocytoma is the soft tissue tumor of histiocytic origin that have a variety of histological patterns. Although cases of malignant fibrous histiocytoma in the head and neck have been reported increasing frequency in recent years, they are rare conditions. We reporeted a case of malignant fibrous histiocytoma of the trachea in which the Patient had been given laryngomicrosurgical biopsy for subglottic mass. Prognosis of malignant fibrous histiocytoma, the use of radiation as primary treatment, and its role in the development of secondary primary tumors in the head and neck region are reviewed.

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Current concepts of craniofacial fibrous dysplasia: pathophysiology and treatment

  • Dong Yeon Kim
    • Archives of Craniofacial Surgery
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    • v.24 no.2
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    • pp.41-51
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    • 2023
  • Fibrous dysplasia is an uncommon genetic disorder in which bone is replaced by immature bone and fibrous tissue, manifesting as slow-growing lesions. Sporadic post-zygotic activating mutations in GNAS gene result in dysregulated GαS-protein signaling and elevation of cyclic adenosine monophosphate in affected tissues. This condition has a broad clinical spectrum, ranging from insignificant solitary lesions to severe disease. The craniofacial area is the most common site of fibrous dysplasia, and nine out of 10 patients with fibrous dysplasia affecting the craniofacial bones present before the age of 5. Surgery is the mainstay of treatment, but the technique varies according to the location and severity of the lesion and associated symptoms. The timing and indications of surgery should be carefully chosen with multidisciplinary consultations and a patient-specific approach.

Pediculated Fibrous Dysplasia in Maxillary Sinus: A Case Report

  • Kim, Jung Ho;Lee, Baek Soo;Kwon, Yong Dae;Choi, Byung Joon;Lee, Jung Woo;Lee, Hyun Woo;Kim, Do Seop;Ohe, Joo Young
    • Journal of Korean Dental Science
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    • v.8 no.1
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    • pp.36-40
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    • 2015
  • Fibrous dysplasia is a bone disorder characterized by progressive replacement of normal bone by fibrous bone tissue. Common involving sites of fibrous dysplasia are the skeletal system including long bones, ribs, craniofacial bones and the pelvis. If maxilla were affected by fibrous dysplasia, antrum is almost always involved. And fibrous dyplasia in maxillary sinus were followed the shape of bone. In our case, the lesion involves antrum but, its shape was different from typical fibrous dysplasia pattern of maxillary sinus. Therefore we report a case of monostotic pediculated fibrous dysplasia in the maxillary sinus with a review of literature.

Radiographic Differential Diagnosis between the Fibrous Dysplasia and the Ossifying Fibroma (섬유성이형성증과 골화섬유종의 방사선학적 감별진단)

  • Choi Karp-Shik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.1
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    • pp.55-63
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    • 1999
  • The author observed and compared the radiographic features of 49 cases of the fibrous dysplasia and 14 cases of the ossifying fibroma in the osteoblastic or mature stage radiologically and histopathologically. The obtained results were as follows: 1. Fibrous dysplasia occurred most frequently in the 2nd decade, but ossifying fibroma in the 3rd and 4th decades, and both lesions occurred with slight predilection in females. 2. In most cases, chief complaints were painless facial swelling. And 61.1% of fibrous dysplasia occurred in the maxilla, 92.9% of ossifying fibroma in the mandible, and most of these lesions occurred in the premolar-molar region. 3. In the mandibular lesions, ossifying fibroma was shown more oval and round shape. but fibrous dysplasia was shown fusiform shape. 4. Fibrous dysplasia was shown homogeneously distributed. complete radiopaque shadow at 63%, and ossifying fibroma was shown concentric. mixed appearance of radiolucent and radiopaque shadow at 92.9%. 5. Fibrous dysplasia was entirely shown poorly outlined and blended to normal surrounding bone, but ossifying fibroma was shown well-defined border. 6. Cortical thinning and expansion were observed in these lesions. but degree of cortical expansion was more severe in ossifying fibroma than fibrous dysplasia. 7. Loss of lamina dura. tooth displacement. and displacement of mandibular canal were observed in both lesions. but root resorption was observed in ossifying fibroma only.

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Fracture Behavior of $Al_2O_3$ Macro-composites with Layered and Fibrous Structure (층상 및 섬유상 $Al_2O_3$ 거시복합체의 파괴거동)

  • 신동우;윤대현;박삼식;김해두
    • Journal of the Korean Ceramic Society
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    • v.34 no.7
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    • pp.758-766
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    • 1997
  • Non-brittle fracture behaviour of the two composite structures made of two different brittle materials was investigated using 3-point bending test. First, the layered and fibrous macro-composites were fabricated using the material easily formed, yet showing a brittle fracture behaviour similar to ceramics. The layered and fibrous Al2O3 /Al2O3 composites with weak interface were also fabricated using plate of 2 mm thickness and rod of 3 mm diameter respectively. Comparison of the mechanical properties between these two structures was performed in the lights of flexural strength and work of fracture for the composites consisting of Al2O3 and simulated materials respectively. The strength ratio of layered structure to the monolith of same volume was 0.6 and the ratio of fibrous one was about 0.2 for the composites made of simulated brittle material. The ratio of the work of fracture of the fibrous to the layered was 0.47. For Al2O3/Al2O3 composites, the strength ratio of layered and fibrous structures to the monolith with same volume were about 0.6 and 0.2 respectively. The ratio of work of fracture of the fibrous to the layered was 0.6. These confirmed that the layered structure was superior to the fibrous one in terms of flexural strength and work of fracture.

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Fracture Charateristics of the Pre-Cracked fibrous Concrete Beams (前 龜裂을 준 鋼纖維 콘크리트보의 破壞特性)

  • Kwark, Kae-Hwan;Park, Jong-Gun;Park, Sai-Woong
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.34 no.2
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    • pp.49-59
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    • 1992
  • In our researches we made mix-design, with the mixing ratio and pre-cracked ratio of steel fibrous different from each other, building the steel fibrous concrete beam which had pre-cracks. To obtain the fracture characteristics of steel fibrous reinforced concrete, series of experiment were conducted on pre-cracked beam subjected to 3-point bending. Thus, we carried out experiments on the destructive characteristics of its pre-crack and post-crack and the result is as follows. 1. The compressive strength of steel fibrous concrete beam increased more slightly than plane beam, and the tensile strength increased 37%, 59%, 94% and 121% respectively when the amount of fibrous was 0.5%, 0.1% 1.5%, and 1.75% respectively. 2. As the amount of steel fibrous mixing increased ant the steel fibrous inhibited the crack growth, the crack condition of steel fibrous concrete beam was retarded irregularly, and this increased fracture load. 3. The defiance of destruction was reduced in the ratio of 1.35 times and 1.22 times respectively when the length of pre-crack was each 2cm and 4cm in comparison with the case of being without the length, and was similar to that of plane beam when the amount of steel fibrous mixing was below 1.0%, and increased linearly when it as above 1.0%. 4. The experimental formula seeking fracture energy was follows and thus we found that the value of fracture energy depended upon tensile strength and the size of speciment. $G_f=K\;{\cdot}\;f_f^'{\cdot}$da/Ec 5. We observed that in the load-strain curve of steel fibrous concrete beam the progress of the crack became slow, compared with plane beam because the crack condition became long to the extent of about 10 times. Concrete was faultiest brittleness fracture through the study, it was known ductile.

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Malignant Transformation of Fibrous Dysplasia on Anterior Skull Base

  • Lee, Chul-Jae;Kim, Seong-Min
    • Journal of Korean Neurosurgical Society
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    • v.37 no.5
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    • pp.383-385
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    • 2005
  • Malignant transformation of fibrous dysplasia is a rare condition and the incidence is estimated at 0.4% for fibrous dysplasia and 4% for Albright's syndrome. The authors did not find a reported case of malignant change at skull base around the orbit in the literature. We experienced a case of fibrous dysplasia, in which neurologic symptoms were aggravated due to malignant change around the orbit, and report its favorable outcome obtained with total surgical removal.

A Radiographic study of Fibro-osseous lesions of the jaw bones (악골 섬유성 골병소의 방사선학적 연구)

  • Kwon Kyung-Yun;Choi Karp-Shik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.28 no.1
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    • pp.27-36
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    • 1998
  • The purpose of this study was to obtain information on the clinical and radiographic features of the fibro-osseous lesions in the jaws. For this study, the author examined and analysed the clinical records and radiographs of 71 cases of 68 patients in fibrous dysplasia, 35 cases of ossifying fibroma and 30 cases of 16 patients of periapical cemental dysplasia diagnosed by clinical and radiographic or histopathological examinations. The obtained results were as followings: L Fibrous dysplasia occurred most frequently in the 2nd decade (30.0%), ossifying fibroma in the 3rd-4th decades, periapical cemental dysplasia in the 4th decade, and all of three lesions showed slight predilection in females. In most cases, chief complaints were painless facial swelling in fibrous dysplasia and ossifying fibroma, and periapical cemental dysplasia was found accidentally in radiographs. 2. Fibrous dysplasia was occurred more frequently in maxilla, ossifying fibroma in mandible and both lesions in premolar-molar area. Periapical cemental dysplasia was occurred most frequently in the mandibular anterior area. The size of fibrous dysplasia was larger than that of ossifying fibroma, and the shape of ossifying fibroma was more round and elliptical than fibrous dysplasia whose was fusiform. 3. Fibrous dysplasia was shown homogeneous radiopaque shadow of 57.6% and ossifying fibroma & periapical cemental dysplasia were shown mixed appearance of radiolucency and radiopacity shadows at 74.2%, 60.0%, respectively. 4. Fibrous dysplasia was entirely shown poorly defined at 87.7%, but ossifying fibroma & periapical cemental dysplasia were shown well outlined at 60.0%, 70.0%, respectively. 5. Cortical thinning and expansion were observed in fibrous dysplasia and ossifying fibroma, and severe in ossifying fibroma than fibrous dysplasia, and those signs were not seen in periapical cemental dysplasia. Loss of lamina dura was dominant in fibrous dysplasia and root resorption was dominant in ossifying fibroma. Displacement of mandibular canal and the degree of the increase of vertical dimension were alike in both lesions. Displacement of maxillary sinus or nasal cavity, thinning & expansion of the maxillary sinus were dominant in fibrous dysplasia. 6. Polyostotic fibrous dysplasia was occurred at 5.9%, Multiple periapical cemental dysplasia at 43.7%. Occurrence rate in the edentulous area of fibrous dysplasia and ossifying fibroma were 7.0%, 8.6%, respectively.

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Monostotic Fibrous Dysplasia in the Metacarpal Bone: A Case Report (중수골에 발생한 단골성 섬유성 이형성증: 1예 보고)

  • Cho, Han-Il;Park, Sung-Hoon;Juhng, Seon-Kwan
    • Investigative Magnetic Resonance Imaging
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    • v.13 no.2
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    • pp.203-206
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    • 2009
  • Fibrous dysplasia is a slowly progressive, benign disorder characterized by fibrous tissue replacement of skeleton and may affect solitary or multiple bones. Monostotic fibrous dysplasia mainly occurrs in the rib, femur and tibia, however, rarely in the hand. We report a case of monostotic fibrous dysplasia confined to the 2nd metacarpal bone with findings of plain radiographs and MR imaging.

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