• International Journal of Internet, Broadcasting and Communication
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• v.13 no.2
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• pp.145-155
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• 2021

With the recent rapid improvement in the standards of life and westernization of dietary lifestyles, the consumption of high-calorie diets such as high-fat and high-protein red meat and instant foods has increased, while less vegetables containing dietary fiber are consumed. In addition to that, stress, erroneous dietary behaviors, and contaminated environments are linked to the risk of developing ulcerative colitis, which is on the rise. Another cause of ulcerative colitis is that involve laxative abuse, including repeated, frequent use of laxatives, and include such conditions as deteriorated bowel function, irritable bowel syndrome, diarrhea, intestinal inflammation, etc. The present study aimed to investigate the comparative evaluation of pharmacological efficacy between sulfasalazine alone and combination with herbal medicine on dextran sodium sulfate (DSS)-induced UC in mice. Balb/c mice received 5% DSS in drinking water for 7 days to induce colitis. Animals were divided into five groups (n = 9): group I-normal group, group II-DSS control group, group III-DSS + sulfasalazine (30 mg/kg), group IV-DSS + sulfasalazine (60 mg/kg), group V-DSS + sulfasalazine (30 mg/kg) + Radish Extract mixture (30 mg /kg) (SRE). DSS-treated mice developed symptoms similar to those of human UC, such as severe bloody diarrhea and weight loss. SRE supplementation, as well as sulfasalazine, suppressed colonic length and mucosal inflammatory infiltration. In addition, SRE treatment significantly reduced the expression of pro-inflammatory signaling molecules through suppression both mitogen-activated protein kinases (MAPK) and nuclear factor-kappa B (NF-κB) signaling pathways, and prevented the apoptosis of colon. Moreover, SRE administration significantly led to the up-regulation of antioxidant enzyme including SOD and Catalase. This is the first report that Radish extract mixture combined with sulfasalazine protects against experimental UC via the inhibition of both inflammation and apoptosis, very similar to the standard-of-care sulfasalazine.

• Composites Research
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• v.34 no.6
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• pp.426-433
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• 2021

The carbon fiber reinforced plastic manufacturing process has a problem in that a dimensional error occurs due to thermal deformation such as residual stress, spring-in, and warpage. The main causes of thermal deformation are various, including the shape of the product, the chemical shrinkage, thermal expansion of the resin, and the mold effect according to the material and surface condition of the mold. In this study, a viscoelastic model was applied to the plate model to predict the thermal deformation. The effects of chemical shrinkage and thermal expansion of the resin, which are the main causes of thermal deformation, were analyzed, and the analysis technique of the 3-D viscoelastic model with and without mold was also studied. Then, the L-shaped mold effect was analyzed using the verified 3D viscoelastic model analysis technique. The results show that different residual deformation occurs depending on the surface condition even when the same mold is used.

• Structural Engineering and Mechanics
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• v.82 no.1
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• pp.121-131
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• 2022

The main goal of this study is to prepare a program for analyzing High Strength Steel Fibrous Reinforced Concrete (HSSFRC) slabs and predict the response and strength of the slab instead of preparing a prototype and testing it in the laboratory. For this purpose, new equations are proposed to represent the material properties of High Strength Steel Fibrous Reinforced Concrete. The proposed equations obtained from performing regression analysis on many experimental results using statistical programs. The finite element method is adopted for non-linear analysis of the slabs. The eight-node "Serendipity element" (3 DoF) is chosen to represent the concrete. The layered approach is adopted for concrete elements and the steel reinforcement is represented by a smeared layer. The compression properties of the concrete are modeled by a work hardening plasticity approach and the yield condition is determined depending on the first two stress invariants. A tensile strength criterion is adopted in order to estimate the cracks propagation. many experimental results for testing slabs are compared with the numerical results of the present study and a good agreement is achieved regarding load-deflection curves and crack pattern. The response of the load deflection curve is slightly stiff at the beginning because the creep effect is not considered in this study and for assuming perfect bond between the steel reinforcement and the concrete, however, a great agreement is achieved between the ultimate load from the present study and experimental results. For the models of the tension stiffening and cracked shear modulus, the value of Bg and Bt (Where Bg and Bt are the curvature factor for the cracked shear modulus and tension stiffening models respectively) equal to 0.005 give good results compared with experimental result.

• Computers and Concrete
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• v.29 no.6
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• pp.407-418
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• 2022

This paper numerically investigates the effect of changes in the mechanical properties (displacement, strain, and stress) of the ultra-high-performance concrete (UHPC) without rebar and the reinforced concrete (RC) using steel re-bars. This reinforced concrete is mostly used in the concrete bridge decks. A mixture of sand, gravel, cement, water, steel fiber, superplasticizer, and micro silica was used to fabricate UHPC specimens. The extended finite element method as used in the ABAQUS software is applied for considering the mechanical properties of UHPC, RC, and ordinary concrete specimens. To calibrate the ABAQUS, some experimental tests have been carried out in the laboratory to measure the direct tensile strength of UHPC by the compressive-to-tensile load converting (CTLC) device. This device contains a concrete specimen and is mounted on a universal tensile testing apparatus. In the experiments, three types of mixed concrete were used for UHPC specimens. The tensile strength of these specimens ranges from 9.24 to 11.4 MPa, which is relatively high compared with ordinary concrete specimens, which have a tensile strength ranging from 2 to 5 MPa. In the experimental tests, the UHPC specimen of size 150×60×190 mm with a central hole of 75 mm (in diameter)×60 mm (in thickness) was specially made in the laboratory, and its direct tensile strength was measured by the CTLC device. However, the numerical simulation results for the tensile strength and failure mechanism of the UHPC were very close to those measured experimentally. From comparing the numerical and experimental results obtained in this study, it has been concluded that UHPC can be effectively used for bridge decks.

• Composites Research
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• v.19 no.1
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• pp.1-8
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• 2006

Prediction of damage caused by low-velocity impact in laminated composite plate is an important problem faced by designers using composites. Not only the inplane stresses but also the interlaminar normal and shear stresses playa role in estimating the damage caused. But it is well known that the conventional approach based on the homogenization has the limit in description of damage. The work reported here is an effort in getting better predictions of dynamic behavior and damage in composite plate using DNS approach. In the DNS model, we discretize the composite plates through separate modeling of fiber and matrix for the local microscopic analysis. In the view of microscopic mechanics with DNS model, interlaminar stress behaviors in the inside of composite materials are investigated and compared with the results of the homogenized model which has been used in the conventional approach to impact analysis. Also the multiscale model based on DNS concept is developed in order to enhance the effectiveness of impact analysis, and we present the results of multiscale analysis considering micro and macro structures simultaneously.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.2A
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• pp.289-295
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• 2008

The purpose of this study was to examine the flexural behavior of reinforced concrete beams strengthened with CFRP strips. A total of 12 rectangular beams were tested. Test variables in this study were the shapes, bonded length and the number of longitudinal layers of CFRP strips. From the experimental study, flexural capacity of the beams strengthened with CFRP strips significantly increased compared to the reinforced concrete beam without a CFRP strip. Maximum increase of ultimate strength was found about 120% more than the control beam. In this test, most of the strengthened beams failed suddenly due to the debonding of CFRP strips. It is also observed that the debonding of the strip was initiated in the flexural zone of the beam and propagated rapidly to the end of the beam. The ultimate tensile strains of CFRP strips in this test were occurred at the level of 36% of rupture tensile strength of the CFRP strip, and an analytical approach to compute the flexural strength of reinforced beams strengthened with CFRP strips based on the effective stresses was conducted.

• Advances in nano research
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• v.15 no.6
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• pp.495-511
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• 2023

In this research, the impact of micro-silica, nano-silica, and polypropylene fibers on the fracture energy of self-compacting concrete was thoroughly examined. Enhancing the fracture energy is very important to increase the crack propagation resistance. The study focused on evaluating the self-compacting properties of the concrete through various tests, including J-ring, V-funnel, slump flow, and T50 tests. Additionally, the mechanical properties of the concrete, such as compressive and tensile strengths, modulus of elasticity, and fracture parameters were investigated on hardened specimens after 28 days. The results demonstrated that the incorporation of micro-silica and nano-silica not only decreased the rheological aspects of self-compacting concrete but also significantly enhanced its mechanical properties, particularly the compressive strength. On the other hand, the inclusion of polypropylene fibers had a positive impact on fracture parameters, tensile strength, and flexural strength of the specimens. Utilizing the response surface method, the relationship between micro-silica, nano-silica, and fibers was established. The optimal combination for achieving the highest compressive strength was found to be 5% micro-silica, 0.75% nano-silica, and 0.1% fibers. Furthermore, for obtaining the best mixture with superior tensile strength, flexural strength, modulus of elasticity, and fracture energy, the ideal proportion was determined as 5% micro-silica, 0.75% nano-silica, and 0.15% fibers. Compared to the control mixture, the aforementioned parameters showed significant improvements of 26.3%, 30.3%, 34.3%, and 34.3%, respectively. In order to accurately model the tensile cracking of concrete, the authors used softening curves derived from an inverse algorithm proposed by them. This method allowed for a precise and detailed analysis of the concrete under tensile stress. This study explores the effects of micro-silica, nano-silica, and polypropylene fibers on self-compacting concrete and shows their influences on the fracture energy and various mechanical properties of the concrete. The results offer valuable insights for optimizing the concrete mix to achieve desired strength and performance characteristics.

• Steel and Composite Structures
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• v.51 no.3
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• pp.243-260
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• 2024

Thirteen self-compacting recycled concrete filled aluminium tubular (SCRCFAT) columns were tested under concentric compression loads. The effects of the replacement ratio of the recycled concrete aggregate (RCA) and steel fibre (SF) reinforcement on the structural performance of the SCRCFAT columns were studied. A control specimen (C000) was cast with normal concrete without SF to be reference for comparison. Twelve columns were cast using RCA, six columns were cast using concrete incorporating 2% SF while the rest of columns were cast without SF. Failure mode, ductility, ultimate load capacity, axial deformation, ultimate strains, stress-strain response, and stiffness of the SCRCFAT columns were studied. The results showed that, the peak load of tested SCRCFAT columns incorporating 5-100 % RCA without SF reduced by 2.33-11.28 % compared to that of C000. Conversely, the peak load of tested SCRCFAT columns incorporating 5-100% RCA in addition to 2% SF increased by 21.1-40.25%, compared to C000. Consequently, the ultimate axial deformation (Δ) of column C100 (RCA=100% and SF 0%) increased by about 118.9 % compared to C000. The addition of 2% SF to the concrete mix decreased the axial deformation of SCRCFAT columns compared to those cast with 0% SF. Moreover, the stiffness of the columns cast without SF decreased as the RCA % increased. In contrast, the columns stiffness cast with 2% SF increased by 26.28-89.7 % over that of C000. Finally, a theoretical model was proposed to predict the ultimate loads tested SCRCFAT columns and the obtained theoretical results agreed well with the experimental results.

• Journal of the Korea Concrete Institute
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• v.19 no.1
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• pp.121-130
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• 2007

To investigate the enhancement in strength and deformation capacities of concrete confined by FRP composites, tests under axial loads were carried out on three groups of thirty six short columns in circular section with diverse GFRP confining reinforcement. The major test variables considered include fiber content or orientation, wrap or tube type by varying the end loading condition, and continuous or discontinuous confinement depending on the presence of vortical spices between its two halves. The circumferential FRP strains at failure for different types of confinements were also investigated with emphasis. Various analytical models capable of predicting the ultimate strength and strain of the confined concrete were examined by comparing to observed results. Tests results showed that FRP wraps or tubes provide the substantial increase in strength and deformation, while partial wraps comprising the vertical discontinuities fail in an explosive manner with less increase in strength, particularly in deformation. A bilinear stress-strain response was observed throughout all tests with some variations of strain hardening. The failure hoop strains measured on the FRP surface were less than those obtained from the tensile coupons in all tests with a high degree of variation. In overall, existing predictive equations overestimated ultimate strengths and strains observed in present tests, with a much larger scatter related to the latter. For more accuracy, two simple design- oriented equations correlated with present tests are proposed. The strength equation was derived using the Mohr-Coulomb failure criterion, whereas the strain equation was based on entirely fitting of test data including the unconfined concrete strength as one of governing factors.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.7
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• pp.1212-1217
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• 2004

The aim of this study was to investigate Quality characteristics of Pleurospermum kamtschaticum to increase the value of functional food resources. To examine Quality characteristics of Pleurospermum kamtschaticum, various factors such as color, texture, fiber, minerals, tannin, crude proteins, crude lipids and sensory quality, were determined using physicochemical methods. The contents of dietary fiber were 0.57％ and 0.54％ in each 100 g of leaf and stem parts (freeze drying base). In mineral content, potassium was the highest value in both of leaf and stem parts (freeze drying base). The contents of tannin were 108.1 $\mu$g/mL and 20.9 $\mu$g/mL in leaf and stem parts (fresh base) respectively. Blanching stems showed significant difference in hardness from freeze-drying leaves. The antioxidative activity in ethanol extracts of Pleurospermum kamtschaticum was investigated using peroxide value and free radical scavenging activity. Free radical scavenging activity in ethanol extracts of Pleurospermum kamtschaticum was 43.5％ in a 100 $\mu$g/mL level, and the antioxidative index was 1.09 in a 500 $\mu$g/mL level. For functional food using Pleurospermum kamtschaticum the contents of crude proteins and lipids were about 9％ and 26％, respectively. The results from sensory evaluation of each treatment older age showed a better acceptability.