• Journal of Veterinary Clinics
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• v.3 no.1
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• pp.235-241
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• 1986

The 587 Holstein cows which calved from January 1983 to December 1984 at an integrated dairy farm in Chung-Nam Province were investigated on incidence of retained fetal membrane. The results obtained were as follows ; 1. The incidence of retained fetal membrane was 15.2% (89 heads) among 587 heads which investigated. 2. The cows which calved in summer showed significantly higher incidence of retained fetal membrane than those which calved in winter(P<0.01), spring and autumn (P<0.05). 3. There was no difference in incidence of retained fetal membrane by calving number.

• Animal cells and systems
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• v.1 no.2
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• pp.337-340
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• 1997

The purpose of this study is to evaluate whether water soluble chitosan, a natural nontoxic chelator, can reduce fetal contamination of radiostrontium in pregnant mice. Various forms of water soluble chitosans (10% or 1% powder, or 1% solution) were given to pregnant mice before or after contamination of 0.005 uCi/B.W(g) Sr-85. Transplacental transfer of Sr-85 to fetus was $6.8{\pm}2.7%$ of injected dose, when Sr-85 was administered at the 20th day of pregnancy. Fetal radioactivity was significantly reduced when mother mice were treated with water soluble chitosan before contamination of Sr-85. Water soluble chitosans of 10% or 1% powder, or 1% solution significantly reduced fetal retention of Sr-85 to $2.3{\pm}0.7%$, $2.7{\pm}0.8%$, and $2.0{\pm}0.9%$, respectively. However, fetal contamination was not reduced, when water soluble chitosans of 10% or 1% powder, or 1% solution were administered after maternal contamination of Sr-85. From these data we can conclude that water soluble chitosan could reduce fetal contamination of radiostrontium in pregnant mice, when given before the pregnant mice were exposed to radiostrontium.

• Journal of Genetic Medicine
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• v.12 no.2
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• pp.72-78
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• 2015

Recently, noninvasive prenatal test (NIPT) has been adopted as a primary screening tool for fetal chromosomal aneuploidy. The principle of NIPT lies in isolating the fetal fraction of cell-free DNA in maternal plasma and analyzing it with bioinformatic tools to measure the amount of gene from the target chromosome, such as chromosomes 21, 18, and 13. NIPT will contribute to decreasing the need for unnecessary invasive procedures, including amniocentesis and chorionic villi sampling, for confirming fetal aneuploidy because of its higher positive predictive value than that of the conventional prenatal screening method. However, its greater cost than that of the current antenatal screening protocol may be an obstacle to the adoption of this innovative technique in clinical practice. Digital polymerase chain reaction (dPCR) is a novel approach for detecting and quantifying nucleic acid. dPCR provides real-time diagnostic advantages with higher sensitivity, accuracy, and absolute quantification than conventional quantitative PCR. Since the groundbreaking discovery that fetal cell-free nucleic acid exists in maternal plasma was reported, dPCR has been used for the quantification of fetal DNA and for screening for fetal aneuploidy. It has been suggested that dPCR will decrease the cost by targeting specific sequences in the target chromosome, and dPCR-based noninvasive testing will facilitate progress toward the implementation of a noninvasive approach for screening for trisomy 21, 18, and 13. In this review, we highlight the principle of dPCR and discuss its future implications in clinical practice.

• Women's Health Nursing
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• v.4 no.2
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• pp.245-257
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• 1998

The characteristics of health behavior related pregnancy and childbirth have reflected on the cultural belief and value in the society. The efforts for women's health promotion through the current illumination of the traditional health care are the prompting assignment to be in nursing. The process of motherhood already progress before the motherhood actually. The functional state as the expectant mother can be the important predicting factor of the postpartum state, the quality of a married life. Motherhood was analyzed by Walker and Avant's method to clarify the concept 'to be a mother' using the various concepts like Koreans' Taekyo, transition to motherhood, maternal identity, maternal role attainment, maternal fetal attachment, and maternal fetal interaction. Upon the concept analysis, naturalness, responsibility, attachment, readiness, controllability were identified as the defining characteristics of motherhood. The antecedents of motherhood were consist of maternal affection, positive self esteem, pregnancy acceptance, fetus recognition and the consequences of motherhood were consist of positive maternal identity, maternal fetal attachment, confidence about the maternal role, the healthy mother and the healthy baby. The empirical referents of motherhood were consists of recognition of motherhood, expectation about motherhood, fetal recognition with ultrasonography and fetal movement, experience of unification between mother and fetus, expression of affection to the fetus, concern about fetal health, concern and practice about Taekyo, adaptation behavior about physical change and discomfort due to pregnancy. Therefore it is necessary to develop the instruction program of motherhood including the defining attributes identified in this study.

• KSBB Journal
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• v.19 no.3
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• pp.210-214
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• 2004

Whole liver transplantation, the currently available treatment of end-stage liver disease, has limitations including serious donor shortage, fatal surgical complications, risk of allograft rejection, and the requirement of life-long immunosuppression. In this study, we investigated the possibility of reconstructing liver tissues in vivo by implanting fetal hepatocytes on polymer scaffolds as a potential method to replace the current treatments. Fetal hepatocytes were freshly isolated from mice and seeded onto porous mesh scaffolds fabricated from polyglycolic acid, a biodegradable synthetic polymer. The seeded scaffolds were implanted into peritoneal cavity of athymic mice for one week. As a control, fetal hepatocytes were implanted without scaffold. One week after transplantation, liver-like tissues formed. Histological and immunohistochemical analyses indicated that the hepatocyles and liver tissue structures (bile ducts) were present in the newly formed tissues. In the control group, no transplanted hepatocytes were observed. Theses preliminary results suggest that liver tissues may be regeneration by transplanting fetal hepatocytes on polymer scaffolds.

• Toxicological Research
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• v.17 no.4
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• pp.279-286
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• 2001

Recently, there is an increasing nationwide concern in Korea that exposure to electric and magnetic fields in the home environment may not be safe in humans. To identify possible effects of horizontally polarized magnetic fields (MF) exposure on embryo-fetal development, timed-mated female Sprague-Dawley rats (24/group) received continuous exposure to 60 Hz MF at field strengths of 0 Gauss (sham control), 50mG,833 mG, or 5000 mG. Dams received MF of sham exposures for 22hr/day on gestation days 6 through 20. Experimentally generated MF were monitored continuously througout the study. There was no evidence of maternal toxicity of developmental toxicity in any MF-exposed groups. Mean maternal body weight, organ weights, and gross findings in groups exposed to MF did not differ from those in sham control. No significant differences in fetal deaths, fetal body weight, and placental weight were observed between MF-exposed groups and sham control. External, visceral, and skeletal examination of fetuses demonstrated no significant differences in the incidence of fetal malformations between MF-exposed and sham control groups. In conclusion, exposure of pregnant Sprague-Dawley rats to 60 Hz at MF strengths up to 5000 mG during gestation day 6-20 did not produce any biologically significant effect in either dams of fetuses.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.320-324
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• 1996

Digital fetal monitoring system based on the personal computer combined with the digital signal processing board was implemented. The DSP board acquires and digitally processes ultrasound fetal Doppler signal for digital rectification, FIR filtering, autocorrelation function calculation, its peak detection and MEDIAN filtering. The personal computer interfaced with the DSP board is in charge of graphic display, hardcopy, data transmission and on-line analysis of fetal heart rate change including and variability. I used a recursive technique for autocorrelation function computation method and MEDIAN filter which can greatly reduce the amount of calculation and accuracy. I also implemented analysis algorithm of fetal heart rate change based on normal fetal sample data in order to exact diagnosis.

• Women's Health Nursing
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• v.25 no.2
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• pp.182-193
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• 2019

Purpose: The purpose of the study was to identify effects of anxiety, social support, and Taegyo practice toward maternal-fetal attachment in pregnant women having an abortion. Method: Participants included 99 pregnant women having an abortion, who participated in this study. Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation, and multiple regression with the SPSS WIN 23.0 program. Results: Maternal-fetal attachment was significantly negatively correlated with anxiety, and significantly positively correlated with social support and Taegyo practice. Spousal support and Taegyo practice, explained 43.8% of participants' maternal-fetal attachment. Conclusion: Results indicate that less anxiety and more social support, and Taegyo practice in pregnant women having an abortion, were associated with stronger maternal-fetal attachment. To strengthen the maternal-fetal attachment of pregnant women having an abortion experience, it would be necessary to develop and implement the Taegyo program, focusing on practicing Taegyo-related encouragement. Additionally, it is recommended that nursing intervention is provided, to encourage families to participate in the Taegyo practice together throughout the gestational period, and to maintain a positive relationship among partners.

• Clinical and Experimental Pediatrics
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• v.65 no.3
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• pp.131-135
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• 2022

Purpose: There is inconsistent evidence about the association between fetal nuchal cord and the risk of autism spectrum disorder (ASD). We performed a meta-analysis to investigate whether fetal nuchal cord is associated with an increased risk of ASD in offspring. Methods: Three main English databases were searched until January 2021. The Newcastle-Ottawa Scale was used to assess study quality. Study heterogeneity was determined using the I 2 statistic, while publication bias was assessed using Begg and Egger tests. Results are presented as odds ratios (ORs) and relative ratios with 95% confidence intervals (CI) and were determined by a random-effects model. Results: Five articles (1 cohort, 4 case-control; 3,088 total children) were included in the present meta-analysis. Fetal nuchal cord was not a risk factor for ASD (OR, 1.11; 95% CI, 0.66-1.57). There was homogeneity among studies that reported a risk of ASD (I²=0.0%). Conclusion: Our results showed that fetal nuchal cord is not a risk factor for ASD. Future large cohort studies should confirm this finding.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.3
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• pp.111-116
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• 2022

In the paper, A prototype Fetal Heart Monitor, mini - size, was designed and produced for pre-mothers to measure the rate and rhythm of their features's heart at home.Pre-mothers could listen fetal heart rhythm through an inner bluetooth speaker ant the monitor. LED colors show the frequency of fetal heart rate variability on the monitor. All measured health information, by ultrasonic resonator and bluetooth speaker, is linked to a mother's smart phone. A test verified this simple measuring device helps users discover the symptoms of fetal health. Patients using at home devices usefully prevent sudden cardiac death and myocardial infraction by discovering symptoms.