• Journal of Nutrition and Health
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• 제51권1호
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• pp.60-72
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• 2018

일생 중 중년기에 해당되는 연령 40 ~ 50대 소비자를 대상으로 성별, 비만도별 일반적 특성, 외식, 음주, 식생활 라이프스타일, 건강한 식생활역량의 차이를 살펴보았으며, 이를 위해 2016년 식품소비행태조사 자료를 이용하여 분석하였다. 그 결과, 첫째, 체중조절 (다이어트)에 대한 관심도는 여성이 남성에 비해 유의하게 높았고, 남녀 모두 비만도가 높을수록 관심도가 높은 특성을 보였다. 실제 식사량 조절 경험 역시 여성이 남성에 비해 매우 높았으며, 남성은 비만수준이 높을수록 식사량 조절경험이 많은 반면, 여성은 과체중군이 가장 많았고 오히려 비만군이 가장 낮았다. 둘째, 외식, 음주와 비만과의 관계는 남성의 경우에만 유의한 것으로 나타났다. 즉, 외식빈도, 월평균 지출비용, 1회 지출비용 수준은 남성이 여성보다 모두 유의하게 높았으며, 이 중 월평균 지출비용, 1회 지출비용은 남성의 경우에만 비만군이 다른 집단에 비해 높은 수준을 보였다. 음주빈도 역시 남성이 여성보다 유의하게 높았으며, 남성의 경우에만 비만도별로 유의한 차이를 보이며 역시 비만군이 정상군보다 높은 수준을 보였다. 남성의 경우 외식유형 중 저녁을 포장마차 등 길거리음식으로 이용하는 횟수가 여성보다 더 높으며 비만군이 정상군 보다 더 높다는 결과 역시 남성의 외식 및 음주 특성과 무관하지 않은 것으로 판단된다. 셋째, 식생활 라이프스타일은 남성과 여성 모두 유사한 요인으로 분류되었으며, 비만도에 따라 차이를 보인 것은 남성의 경우, 건강 및 고급추구와 가격추구 식생활 라이프 스타일 등 2개 요인이며, 여성의 경우는 고급추구와 안전 추구 식생활 라이프스타일 등 2개 요인이다. 그리고 남녀 모두 정상군이 비만군보다 해당 라이프스타일의 성향을 더 갖는 것으로 나타났다. 넷째, '건강한 식생활 역량' 수준은 여성이 남성에 비해 지식, 실천 수준 모두 높았으며, 비만도에 따른 차이는 여성의 경우에만 유의하였다. 즉, 여성 중 정상군은 비만군에 비해 건강한 식생활 역량의 지식, 실천 수준이 모두 유의하게 높았으며, 특히 실천부분이 비만도와의 관련성이 더 큰 것으로 나타났다.

• 디지털융복합연구
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• 제11권8호
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• pp.219-225
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• 2013

본 연구는 아동의 안면 연부조직에 발생되는 열상에 영향을 미치는 요인을 확인하기 위한 서술적 조사 연구이다. 자료 수집은 2010년 4월부터 2011년 5월까지 인천 I 종합병원의 응급실에 내원 후 성형외과에 의뢰되어 치료한 소아 안면열상 환자 126명을 대상으로 실시하였다. 분석결과 모든 연령별로 남녀의 발생 빈도는 유의한 차이를 보였다(p<.05). 손상 발생 장소는 집 밖에서 발생된 경우가 49%, 손상의 원인은 미끄러짐(42%), 부딪침(40%)이 많았다. 계절별로는 여름이 30.2%로 가장 많았고, 발생 시간대는 12~16시가 56%로 가장 많이 발생되었다. 손상 후 내원시간은 1시간 이내의 경우가 대부분(83%) 이었다. 손상 부위는 이마부위 발생 빈도가 가장 높게 나타났고(26%), 손상의 깊이는 피하조직까지 손상된 경우가 54%, 손상의 길이는 1~2cm가 46%로 가장 많았다. 손상 국소마취를 통해 봉합치료한 경우는 40%, 동반골절이 있는 경우는 4명(1.53%)이었다. 결론적으로 안면 열상 후 봉합으로 영구적인 상흔을 남길 수 있으며, 외모의 기형을 초래할 수 있으므로 발생 상황과 손상기전에 대한 상세한 조사를 통해 보다 안전한 생활환경을 조성하는 방법을 모색하고 아동의 사고 발생을 예방하기 위한 안전 교육이 필요하겠다.

• 한국응용곤충학회지
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• 제48권3호
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• pp.347-354
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• 2009

본 연구는 차먼지응애의 천적인 오이이리응애의 생물적 방제효과를 조사하였다. 차먼지응애는 상위 엽을 가해하다가 밀도가 높아짐에 따라 먹이조건이 나빠지기 때문에 새로운 서식처를 찾아 이동하였다. 오이이리응애와 차먼지응애의 밀도변동은 먹이충인 차먼지응애의 이동에 따라 천적인 오이이리응애의 서식지가 같아졌다. 차먼지응애에 대해 천적인 오이이리응애의 포식량은 15, 20, 25 및 $30^{\circ}C$에서 각각 8.8, 15.2, 27.0 및 30.3마리를 포식하였다. $25^{\circ}C$ 조건하에서 부화유충은 0.5마리, 전약충은 1.6마리, 후약충은 5.2마리, 수컷 성충은 3.8마리, 암컷 성충은 27.0마리의 차먼지응애 성충을 포식하였다. 차먼지응애 성충에 대한 오이이리응애 성충의 기능반응은 차먼지응애의 밀도가 증가함에 따라 포식량은 점차 증가하였으나 그의 포식율은 감소하여 Holling의 기능반응곡선 제II형과 일치하였다. 천적인 오이이리응애와 먹이충인 차먼지응애 접종비율이 고추에서 1:40일 경우 밀도억제효과가 98% 이상으로 가장 효과적이었다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.463-467
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• 2012

Purpose: To assess the safety and efficacy of a gemcitabine plus docetaxel regimen as a second line therapy for patients with advanced soft tissue sarcoma (STS) resistant to doxorubicin and ifosfamide-based therapy. Patients and Methods: Medical records of 64 patients with advanced STS who received gemcitabine plus docetaxel regimen as a second line treatment between May 2006 and June 2011 were examined. All patients had been previously treated with doxorubicin plus ifosfamide-based regimen at first line setting. Patients received gemcitabine 900 $mg/m^2$ on days one and eight intravenously over 90 minutes, followed by docetaxel 75 $mg/m^2$ on day eight intravenously over one hour. Cycles were repeated every 3 weeks. Results: The male-to-female ratio was 37/27 and the median age was 44 years (range; 19-67 years). Objective responses were observed in 13 (20.3 %) patients (2 CR, 11 PR) and stable disease in 21 (32.8 %). Total clinical benefit (CR+PR+SD) was observed in 34 (53.1 %). Median overall survival (OS) was 18 months (95% confidence interval (CI):12.1-23.9) and Median time to progression (TTP) was 4.8 months (95% CI: 3.6-6). A total of 243 cycles of chemotherapy were administered. The median number of cycle was 3 (range;1-11). The most common grade 3-4 hematologic toxicity was neutropenia (35.9 %). The most common nonhematologic toxicities consisted of nausea/vomiting (37.5 %), mucositis (32.8 %), peripheral neuropathy (29.7%), and fatigue (26 %). There was no toxicity-related death. Conclusion: The combination of gemcitabine plus docetaxel is an active and tolerable regimen as a second line therapy for patients with advanced soft tissue sarcoma who have failed doxorubicin and ifosfamide-based therapy.

• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8495-8497
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• 2014

Purpose: To investigate whether it is safe to use leucogen tablets 60 mg three times per day (180 mg for a day) and whether this regimen could reduce the incidence of febrile neutropenia caused by chemotherapy. Methods: This prospectively designed study focused on the safety and effectiveness of leucogen tablets 60mg three times per day for a group of cancer patients during chemotherapy for mainly lung or gastric cancers. The tablets were administered from 5 days before until the termination of chemotherapy. Neutropenia and other healthcare encounters were defined as events and occurrence was estimated for comparison. Results: We identified 39 patients receiving leucogen tablets 60mg three times per day, including 11 with gastric, 12 with lung and 16 with other sites of cancer. The mean age was 65 (29-75) years and there were 27 male and 12 female patients. The mean duration of leucogen tablets intake was 59 days. Eighteen patients were treated with taxane-based, 4 with irinotecan-based and 17 with other chemotherapy. The incidence of febrile neutropenia was 0%. Twelve patients were found severe neutropenia (grade III/IV), and the duration of severe neutropenia (grade III/IV) was 5 days. Treatment-emergent adverse events were attributable to complications of myelosuppressive chemotherapy or the primary disease (i.e., alopecia, nausea, asthenia, neutropenia, and severe hepatic renal dysfunction). No chemotherapy was delayed and no treatment related death was observed. Conclusions: This study suggested that leucogen tablets 60mg three times per day (180mg for a day) are safe and could be effective for preventing febrile neutropenia in patients with chemotherapy.

• 대한지역사회영양학회지
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• 제20권5호
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• pp.327-337
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• 2015

Objectives: Dietary life is closely associated with dietary attitude and diet-related knowledge. Particularly, dietary habit such as sodium intake can be affected by various dietary behaviors such as food choices, dietary attitude toward salty food and a preference for salty taste. The purpose of this study was to assess sodium-related nutrition knowledge and to identify sodium-related attitude and behaviors according to the level of sodium-related knowledge of university students. Methods: Anthropometric measurements were provided by 408 students who participated in this study. The study participants answered questionnaires to provide information on general dietary behaviors, sodium-related dietary attitude and other behavioral factors. A total score of nutrition knowledge was used to categorize study participants in to two groups, namely, low level in sodium-related knowledge (LNaK) or high level in sodium-related knowledge (HNaK) and the attitude and the behaviors of students toward sodium intake were compared between these two groups. Results: The ratio of female students in HNaK group was higher than that in the LNaK group. HNaK group had a higher score in checking nutrition label of processed food than the LNaK group. Total score of sodium-related attitude and behaviors of HNaK group were 34.81 and 32.75, respectively and these scores were significantly higher than that of the LNaK group whose scores were 32.57 and 30.57, respectively. Total energy intake was not different between two groups but the intakes of calcium, vitamin B2 and folate were higher in HNaK group than in the LNaK group. Correlation analysis adjusted for age and gender revealed that total score of sodium-related nutrition knowledge was positively correlated with total score of sodium-related attitude and behaviors. Conclusions: In conclusion, students who had high level of sodium-related nutrition knowledge had desirable attitude and behaviors toward sodium intake and these results can be considered in nutrition education for university students.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2001년도 발생공학 국제심포지움 및 학술대회 발표자료집
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• pp.37-43
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• 2001

1. About fifty thousand of cattle embryos were transferred and 16000 ET-calves were born in 1999. Eighty percents of embryos were collected from Japanese Black beef donors and transferred to dairy Holstein heifers and cows. Since 1985, we have achieved in bovine in vitro fertilization using immature oocytes collected from ovaries of slaughterhouse. Now over 8000 embryos fertilized by Japanese Black bull, as Kitaguni 7~8 or Mitsufuku, famousbulls as high marbling score of progeny tests were sold to dairy farmers and transferred to their dairy cattle every year. 2. Embryo splitting for identical twins is demonstrated an useful tool to supply a bull for semen collection and a steer for beef performance test. According to the data of Dr. Hashiyada(2001), 296 pairs of split-half embryos were transferred to recipients and 98 gave births of 112 calves (23 pairs of identical twins and 66 singletons). 3. A blastomere-nuclear-transferred cloned calf was born in 1990 by a joint research with Drs. Tsunoda, National Institute of Animal Industry (NIAI) and Ushijima, Chiba Prefectural Farm Animal Center. The fruits of this technology were applied to the production of a calf from a cell of long-term-cultured inner cell mass (1988, Itoh et al, ZEN-NOH Central Research Institute for Feed and Livestock) and a cloned calf from three-successive-cloning (1997, Tsunoda et al.). According to the survey of MAFF of Japan, over 500 calves were born until this year and a glaf of them were already brought to the market for beef. 4. After the report of "Dolly", in February 1997, the first somatic cell clone female calves were born in July 1998 as the fruits of the joint research organized by Dr. Tsunoda in Kinki University (Kato et al, 2000). The male calves were born in August and September 1998 by the collaboration with NIAI and Kagoshima Prefecture. Then 244 calves, four pigs and a kid of goat were now born in 36 institutes of Japan. 5. Somatic cell cloning in farm animal production will bring us as effective reproductive method of elite-dairy- cows, super-cows and excellent bulls. The effect of making copy farm animal is also related to the reservation of genetic resources and re-creation of a male bull from a castrated steer of excellent marbling beef. Cloning of genetically modified animals is most promising to making pig organs transplant to people and providing protein drugs in milk of pig, goat and cattle. 6. Farm animal cloning is one of the most dreamful technologies of 21th century. It is necessary to develop this technology more efficient and stable as realistic technology of the farm animal production. We are making researches related to the best condition of donor cells for high productivity of cloning, genetic analysis of cloned animals, growth and performance abilities of clone cattle and pathological and genetical analysis of high rates of abortion and stillbirth of clone calves (about 30% of periparutum mortality). 7. It is requested in the report of Ministry of Health, labor and Welfare to make clear that carbon-copy cattle(somatic cell clone cattle) are safe and heathy for a commercial market since the somatic cell cloning is a completely new technology. Fattened beef steers (well-proved normal growth) and milking cows(shown a good fertility) are now provided for the assessment of food safety.

• 대한예방한의학회지
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• 제11권2호
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• pp.71-86
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• 2007

This study aims at looking into the use of oriental medical services in treating disease and patient's attitude of oriental medicine by social classes. The first to be explored through this study is medical accessibility, classifying them by age, gender and job. Second is to examine kinds of oriental medical services and expenses incurred in treating the disease. Third is to compare satisfaction for the services offered and investigate into relations between disease and oriental medicine through cross-analysis by class, and provide fundamental materials for enhancing accessibility to oriental medical centers for treating chronic diseases. The 1,376 households for the period of time from Apr. to Jun. 2005, were asked to answer to the questionnaires offered. The conclusion from the survey can be summarized as follows. Medical services for the onset of disease were less offered to females, older group, low schooling, and low-income bracket. It is attributable to an economic cause, in both genders. The in- and outpatients' rate were found higher in groups of female, older age, low-income and blue-color workers. Use of oriental medical centers were higher in outpatients than inpatients probably for low-income brackets were less frequently put on regular physical checkups, more exposing to diseases. Each hospitalization was found over six days longer in average; 19.7 days for oriental medical hospitals, 12.5 for hospitals. The hospital charges that patients should pay for one hospitalization showed 909,000 won in oriental medical hospitals, much higher than 518,000 won in hospitals. Outpatients were also found to pay more for oriental medical services; 55,000 won for oriental medical hospitals, 19,000 for hospitals. As to outpatients' satisfaction, oriental medical hospitals were generally found to be a little more satisfactory than general hospitals; 11.2% of respondents answered Very Satisfactory. Satisfaction to services offered to outpatients showed 82.2% of respondents responded to Over Satisfactory for herb clinics, 76% for general hospitals. For future intention to use oriental medical services, females, over 51 years old, lower education and income, and blue color workers showed more intention to use them. To be more competitive in treating chronic diseases, it is necessary that oriental medical services become more accessible through extending its coverage of insurance into more medical herbs and their prepared packs, as well as mapping out extensive publicity strategies to make known to the public about high efficacy of medical herbs and their safety.

• Journal of Chest Surgery
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• 제42권3호
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• pp.401-403
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• 2009

63세 여자 환자의 악성 흉선종 절제수술 시에 횡격막 신경의 절제 및 복원술이 시행되었다. 수술 소견상 좌측 횡격막 신경이 2 cm정도의 길이로 종양에 완전히 둘러싸여 있어서 위아래로 5 mm 길이의 여유를 두고 3 cm정도의 횡격막 신경을 절제하였으며 직접 단단 문합 하였다. 수술 후 11개월에 시행한 투시진단에서 양측 횡격막은 적절하고 대칭적인 움직임을 보임으로서 신경기능의 회복을 시사했다. 수술 후 30개월에 시행한 폐 기능 검사 결과는 수술 전의 소견과 유사하였다. 환자는 재발 없이 현재 외래 추적 관찰 중이다.

• 생물정신의학
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• 제7권2호
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• pp.191-197
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• 2000

Objectives : Risperidone is a new antipsychotic drug developed to overcome the therapeutic limitation of conventional antipsychotics. It responses to negative as well as positive symptoms by blocking both dopaminergic and serotonergic receptors, causing no significant side effects such as agranulocytosis and seizure. It is, however, not known whether it induces any serious cardiovascular side effects as evoked by other conventional antipsychotic drugs. The aims of this study were to evaluate the effect of risperidone on cardiovascular function, and to discuss the factors affecting the cardiovascular function. Methods : For 42 patients(22 males and 20 females) diagnosed as schizophrenia, schizophreniform disorder or schizoaffective disorder according to the DSM-IV classification, the cardiovascular fuctions such as heart rate, systolic and diastolic blood pressure, PR interval, QRS interval and QT interval were successively checked before and after 2 weeks and 4 weeks risperidone administration. Furthermore, variables such as body weight, Brief Psychiatric Rating Scale(BPRS), Clinical Global Impression(CGI), Extrapyramidal Symptom Rating Scale(ESRS), Anticholinergic Rating Scale(ARS), serum cholesterol level, serum triglyceride level, serum high-density-lipoprotein level, serum WBC, serum Hb, serum platelet level, prothrombin time and partial thromboplastin time were also analyzed before and after 2 weeks and 4 weeks risperidone administration. Results : 1) Risperidone treatment resulted in a significantly decreased heart rate and increased QT interval after 4 weeks administration(p<0.005 respectively). 2) The scores of BPRS and CGI were significantly decreased after 2 weeks and 4 weeks risperidone administration as compared with baseline(p<0.001 respectively). The scores of ESRS and ASRS were significantly increased after 2 weeks and 4 weeks risperidone administration as compared with baseline(p<0.001 respectively). 3) There were positive correlations between heart rate after 4 weeks and total dose(P<0.05). Blood pressure was significantly(p<0.05) correlated with sex(higher in male) and significantly(p<0.05) positive correlated with body weight. QT interval was significantly(p<0.05) correlated with sex(longer in female) and smoking history(shorter in smokers). Conclusions : Risperidone could induce significant change in heart rate and Q-T interval. Therefore, the cardiovascular safety for risperidone should be reconsidered according to the duration and dosage increase.