• Journal of Korean Biological Nursing Science
• /
• v.19 no.1
• /
• pp.1-10
• /
• 2017

Purpose: The purpose of this study was to investigate influences of drinking, smoking, and obesity indices on cardio-cerebrovascular disease risk factors in Korean young men. Methods: The subjects were 234 young men, aged 20 to 39 years. Body mass index (BMI), percent body fat (PBF), body fat mass (kg), and waist hip ratio (WHR) were measured as obesity indices. Systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured as cardio-cerebrovascular disease risk factors. The data were analyzed by t-test, ANOVA, Pearson's correlation coefficient, and multiple regression analysis using SAS 9.4. Results: Statistically significant factors were BMI for SEP; age, degree of drinking, body fat mass for DBP; WHR for TC; WHR and age for TG; age, degree of smoking and PBF for HDL-C; WHR, age and degree of smoking for LDL-C. Conclusion: Factors identified in this study need to be considered in cardio-cerebrovascular disease prevention programs for young men.

• Research in Community and Public Health Nursing
• /
• v.15 no.1
• /
• pp.29-35
• /
• 2004

Purpose: The purpose of this study was to investigate the computer input frequency of blood glucose self testing in type2 diabetic patients, for three months. Method: 39 participants were recruited from the endocrinology outpatient department of a tertiary care hospital in an urban city. The computer input frequencies were measured by patients' log in and input of http://www.biodang.com. Glycosylated haemoglobin was determined by a high performance liquid chromatography technique and fasting blood glucose was analyzed by the glucose oxidase method. Diabetes knowledge was measured by a 19 item diabetes knowledge test. Results: The computer input frequency of before breakfast blood glucose was 33.5 for three months. The total blood glucose input frequency tended to be lower in female, aged patients, middle school graduates, those who have no spouse and job, those who have no insulin treatment, obese subjects, and hyperglycemia patients, than in their counterparts. The diabetic knowledge was positively correlated with the computer input frequency of blood glucose self testing. Conclusion: An educational program should be developed to increase the computer input frequency of blood glucose self testing in type2 diabetic patients.

• Asian Journal for Public Opinion Research
• /
• v.2 no.2
• /
• pp.121-139
• /
• 2015

"Living in the present moment," a Buddhist concept, was applied in this research. This concept urges the patients to cling neither to the past nor the future as well as being mindful of their body, feelings, mind, and mental qualities. The purpose of the study was to develop a "living in the present moment" model and to evaluate the power of "living in the present moment" in terms of physical and mental results. The study used non-participatory action research with quasi-experimental research design that included 3 camps composed of 6 main activities. The percentages, SD, and paired t-test statistics were used to analyze and compare 17 purposively selected diabetic patients from Pak Thong Chai Hospital before and after they attended the 3 camps. The patients improved significantly in terms of waistline, body weight, body mass index (BMI) and blood pressure (SBP and DBP). The mean of fasting plasma glucose (FPG) level was also changed considerably. The results revealed that the treatment helped the patients to gain self-awareness and self-realization (Yonisomanasikara), as well as knowledge and increased support from friends (Kalyanamitta). They also let go of their attachment to their physical and mental oppressions. This helped the patients to relieve their daily pain, fatigue, insomnia, and diabetes-related complications. About 75% of all patients were able to achieve lifestyle modifications. Therefore, implementation of the model should be expanded and utilized in other diabetic centers. The model might also be expanded to pre-diabetes.

• The Korean Journal of Community Living Science
• /
• v.14 no.3
• /
• pp.67-73
• /
• 2003

This study was carried out to investigate the supplementary effects of the rice germ oil compared with soy bean oil on blood glucose level of non-insulin dependent diabetic mice. Forty diabetic KK mice were fed two kinds of experimental diets with 20% lipid from soy bean oil as a control(CO) and rice germ oil(RG) for 8 weeks, respectively. Diet intake, body weight, organs weights and lipids levels of serum, liver and feces were measured. There was no significant difference in food and water intake, body weight gain and organs weights between experimental groups. The concentrations of fasting and random blood glucose were similar between CO and RG groups. There was no significant difference in blood glucose levels after glucose treatment during the glucose tolerance test between two groups. The levels of $HbA_{1c}$ as the index of blood glucose status, and insulin were similar in two groups. These results suggested that rice germ oil can't reduce blood glucose concentration of non-insulin dependent diabetic mice compared with soybean oil. But we need to investigate the hypoglycemic effect of rice germ oil by changing supplementary level and period.

• Journal of Biomedical Engineering Research
• /
• v.22 no.4
• /
• pp.369-375
• /
• 2001

The statistical regression model is one of the most frequently used clinical analysis methods. It has basic assumption of linearity, additivity and normal distribution of data. However, most of biological data in medical field are nonlinear and unevenly distributed. To overcome the discrepancy between the basic assumption of statistical model and actual biological data, we propose a new analytical method based on artificial neural network. The newly developed multilayer perceptron(MLP) is trained with 120 data set (60 normal, 60 patient). On applying test data, it shows the discrimination power of 0.76. The diabetic risk factors were also identified from the MLP neural network model and the logistic regression model. The signigicant risk factors identified by MLP model were post prandial glucose level(PP2), sex(male), fasting blood sugar(FBS) level, age, SBP, AC and WHR. Those from the regression model are sex(male), PP2, age and FBS. The combined risk factors can be identified using the MLP model. Those are total cholesterol and body weight, which is consistent with the result of other clinical studies. From this experiment we have learned that MLP can be applied to the combined risk factor analysis of biological data which can not be provided by the conventional statistical method.

• Journal of Korean Medicine Rehabilitation
• /
• v.21 no.4
• /
• pp.157-165
• /
• 2011

Objectives: The aim of this study is to establish the association of GNB3 with obesity-index, blood pressure, glucose and lipid level. Methods: A total of 209 Korean obese subjects participated in the study. Body weight, body mass index(BMI), waist circumference, body fat, body fat mass, resting metabolic rate, blood pressure, total cholesterol, high density lipoprotein, triglyceride and fasting blood sugar test were measured by using standardized protocols. The GNB3 was genotyped by using polymerase chain reaction with restriction fragment length polymorphism. Results: The frequency of CC, CT, TT genotype were, respectively, 18,2%, 56.9%, 24,9%, and the frequency of T allele was 53.3% in Korean obese population. There were no association of GNB3 with obesity index, blood pressure, glucose and lipid level in Korean obese population. Conclusions: Obese Korea population have a higher frequency of T alle than general Korean population. There are no association of GNB3 with obesity index, blood pressure, glucose and lipid level in Korean obese population.

• Perspectives in Nursing Science
• /
• v.10 no.2
• /
• pp.111-119
• /
• 2013

Purpose: The purpose of this study was to determine the effects of 6 months lifestyle coaching program for adults with hypertension. Methods: The study utilized the one-group pretest-posttest design. The subjects were recruited from a corporation group member of a private health maintenance organization. The data of 35 subjects who completed the program out of initial 114 subjects were analyzed for this study. The program included 6 times of monthly face-to-face visits and additional short messages by cellular phone. They were given education for self-management of hypertension and coaching for lifestyle modification. Dependent variables were measured at the beginning and at the end of 6months program and compared by paired t-test. Results: There were significant reductions in systolic and diastolic BP, BMI, total cholesterol, and fasting blood sugar. Among the variables in life style, significant changes were shown in alcohol consumption (frequency and quantity) and exercise (frequency and duration). Conclusion: This study showed that 6 months lifestyle coaching program has potential for positive outcomes on BP control and modifying lifestyle for adults with hypertension. However, additional study is needed to find sustainability of lifestyle and the long-term effect of the program with larger sample.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.24 no.4
• /
• pp.20-30
• /
• 2011

Purpose: Polycystic ovary syndrome(PCOS) is a common condition characterised by menstrual abnormalities. PCOS is now recognised to be a metabolic syndrome which may include hyperinsulinemia, hyperlipidemia, diabetes mellitus and possibly cardiac disease. Cyperi Rhizoma(CR) can soothe the liver to regulate gi and regulate menstruation to relieve pain. For these reasons, this study was designed to investigate the effects of CR on metabolic syndrome in PCO rats. Methods: Female rats injected with a single dose of 2 mg/kg estradiol valerate (EV) develop PCO, CR was given for 5 weeks. After 5 weeks administration of drugs, body weights, food uptake, Fasting Blood Glucose, Oral Glucose Tolerance Test, Total Cholesterol, HDL-Cholesterol, LDL-Cholesterol and Triglyceride were measured once a week. Results: In this experiment, single injection of EV induced hyperlipidemia, but it did not affect serum glucose levels. Oral administration of CR prevent weight loss shown in control group. In addition, treatment with CR can lower total cholesterol, LDL-cholesterol and triglyceride in serum compared to PCO induced control group. Conclusions: These results suggest that CR can regulate hyperlipidemia in PCOS.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.25 no.2
• /
• pp.264-269
• /
• 2011

This study was designed to investigate the effects of Cinnamomi Cortex extract (CC) on hypercholesterolemia induced by Estradiol valerate (EV) in female rats. We investigated the effects of CC on Changes in body weights for 5 weeks. In addition, we examined the effects on fasting blood glucose (FBS) and tested oral glucose tolerance test after oral administration of CC for 5 weeks. We also investigated the effects on levels of total cholesterol, HDL-cholesterol and LDL-cholesterol in serum. Treatment with CC restored weight gain rates suppressed by EV significantly. CC did not affect serum glucose level and glucose tolerance. Levels of total cholesterol and triglyceride were lowered by administration of CC compared to EV treated control respectively. These result suggest that CC can lower serum cholesterol level then prevent weight loss induced by EV. We also suggest the possibility as anti-hyperlipidemic agent of CC.

• Journal of Korean Biological Nursing Science
• /
• v.20 no.4
• /
• pp.261-269
• /
• 2018

Purpose: The purpose of this study was to investigate the prevalence of metabolic syndrome and diagnostic components in adult women. Methods: The subjects of this study were 12,016 women that were aged twenty years or older and underwent an annual health check-up for National Health Insurance Service (NHIS) from 2009 to 2013. Data including blood pressure, waist circumstance, fasting glucose, triglyceride, and high density lipoprotein cholesterol (HDL-C) were received from the NHIS. This data was analyzed through the use of descriptive statistics, ${\chi}^2$-test, and multiple logistic regression. Results: The prevalence of metabolic syndrome and diagnostic components increased with age. In the five diagnostic components of the metabolic syndrome, the prevalence of low HDL-C was highest in 20s to 40s. The prevalence of high blood pressure was highest in the people aged fifty or older. The risk of metabolic syndrome in 2013 was higher in women with abnormal diagnostic component of metabolic syndrome in 2009 and highest in women with abnormal waist circumstance in 2009. Conclusion: There was a need to investigate the prevalence of metabolic syndrome components according to age. Education on metabolic syndrome was required for those that had one or two abnormal diagnostic components. The risk of abdominal obesity related to metabolic syndrome needs to be emphasized. Moreover the education for management of abdominal obesity also needs to be emphasised.