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Effects of Cinnamomi Cortex on Hypercholesterolemia Induced by Estradiol Valerate in Rats  

Choi, Eu-Gene (School of Korean Medicine, Pusan National University)
Kim, Hyung-Woo (School of Korean Medicine, Pusan National University)
Chung, Hee-Jin (School of Korean Medicine, Pusan National University)
Joung, Young-Min (School of Korean Medicine, Pusan National University)
Shin, Dong-Sung (School of Korean Medicine, Pusan National University)
Cho, Su-In (School of Korean Medicine, Pusan National University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.25, no.2, 2011 , pp. 264-269 More about this Journal
Abstract
This study was designed to investigate the effects of Cinnamomi Cortex extract (CC) on hypercholesterolemia induced by Estradiol valerate (EV) in female rats. We investigated the effects of CC on Changes in body weights for 5 weeks. In addition, we examined the effects on fasting blood glucose (FBS) and tested oral glucose tolerance test after oral administration of CC for 5 weeks. We also investigated the effects on levels of total cholesterol, HDL-cholesterol and LDL-cholesterol in serum. Treatment with CC restored weight gain rates suppressed by EV significantly. CC did not affect serum glucose level and glucose tolerance. Levels of total cholesterol and triglyceride were lowered by administration of CC compared to EV treated control respectively. These result suggest that CC can lower serum cholesterol level then prevent weight loss induced by EV. We also suggest the possibility as anti-hyperlipidemic agent of CC.
Keywords
Cinnamomi Cortex; hyperlipidemia; hypercholesterolemia; herbal medicine;
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Times Cited By KSCI : 9  (Citation Analysis)
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