• 대한수의학회지
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• 제44권2호
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• pp.311-315
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• 2004

The detection of lymph node metastasis is an important step in tumor staging and is significant for therapy planning. It has been challenged to yield an appropriate image with diagnostic methods such as Magnetic Resonance (MR) and Computed Tomography (CT). Though CT has been used widely and accessed easily to show internal organs, it can hardly provide difference between lymph node and adjacent vessel or fat tissue. It has been well established that MR can reveal the subtle discrepancy within soft tissue. This study investigated the suitability of MR lymph node imaging without contrast enhancement by comparison of T1-weighted image (T1WI) and T2- weighted image (T2WI) in ten normal rabbits. According to the pulse sequence optimized from preliminary study, T1-weighted spin-echo (repetition time/echo time=400/12 ms) and T-2 weighted fast spin-echo (repetition time/echo time=3500/84 ms) images covering the hind limbs and pelvic region were acquired at 1.5 T. Two radiologists scrupulously evaluated the MR images in consensus. And signal intensity of lymph nodes was compared with that of adjacent fat. Statistical analysis showed that T1-weighted coronal image visualized the lymph nodes (iliac, superficial inguinal and popliteal lymph nodes) quickly and consistently rather than T2-weighted one. Conclusively, T1WI for evaluation of lymph nodes is moderately better than T2WI and appears to have potential for quick and sufficient mapping of the lymph nodes. In addition, this normal MR image of lymph nodes could be applied to further study for the evaluation of lymphatic system in abscess and tumor bearing animal model.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 제5회 학술대회 논문집 일렉트렛트 및 응용기술연구회
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• pp.33-37
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• 2003

Endovaginal and endorectal receiver only surface coil were designed for MR imaging(MRI) and $^1H$ MR spectroscopy(MRS) for the uterine cervix and the prostate. The shape of endovaginal coil wire was rectangular with round comer. The shape of endorectal coil wire was long elliptic shape during insertion and circular shape after insertion. Conventional spin echo and fast spin echo sequences were used as T1 and T2 weighted imaging sequences, respectively. 3D volume localized in vivo $^1H$ MR spectroscopy of the human cervix and prostate was performed using PRESS or STEAM localization method. Using home-built endvaginal and endorectal coils, excellent T1 and T2 images were obtained to visualize early cervical and prostate tumors. 3D volume localized in vivo $^1H$ MRS was useful to differentiate the cancerous tissue from the normal tissue.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.341-342
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• 2007

3T MRI system에서 고해상도 영상을 얻기 위해서는 magnetic field를 균일하게 만들어야 한다. 특히 초고속 영상 기법인 Spiral scan 방식과 EPI scan 방식에서는 이미지 영역에서의 magnetic field의 inhomogeneity에 의해 영상의 왜곡이 심해진다. 본 논문에서는 magnetic field의 inhomogeneity를 단시간 내에 측정하기 위해 fast spin echo방식의 pulse sequence 제안하고, magnetic field를 분석하기 위한 field map의 구성과, field pattern의 효과적인 분석을 통하여, magnetic field를 균일하게 만드는 방법을 제안한다.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.40-40
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• 2003

The purpose of this study was to characterize focal hepatic lesions through pre and post ferucarbotran-enhanced T2 and T2＊-weighted imaging and to help differentiate benign and malignant lesions 대상 및 방법： Consecutive 34 patients with 52 hepatic lesions underwent MRI before and after intravenous bolus injection of ferucarbotran (Resovist Sobering, Berlin, Germany) for evaluation of focal hepatic lesions. Lesions included hemangiomas (n=17), metastases (n=12), cysts (n=10), hepatocellular carcinomas (n=8), dysplastic nodules (n=4), and focal fat deposit (n=1). T2-weighted fast spin echo (TR/TE： 4060/138) and gradient echo T2＊-weighted images(TR/TE： 140/5.3, FA = 90) were obtained according to the institutional routine imaging protocol. Lesional signal-intensity and lesion-to-liver contrast changes were measured by contrast-to-noise ratio (CNR) from region of interest.

• Journal of Magnetics
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• 제21권2호
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• pp.281-285
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• 2016

The purpose of study was to evaluate SNR and CNR with different contrast agent contents (1.0 mmol/mL gadobutrol and 0.5 mmol/mL gadoterate meglumine) for spin echo (SE) and 3-dimension contrast-enhanced fast field echo (3D CE-FFE) pulse sequences. In this study, we compared the SNR and the CNR between 0.5 mmol/mL gadoterate meglumine and 1.0 mmol/mL gadobutrol according to the concentration of contrast agent in brain MRI. When we compared between SE and 3D CE-FFE pulse sequences, the higher SNR and CNR using 3D CE-FFE pulse sequence can be acquire regardless of contrast agent contents. Also, a statistically significant difference was found for SNR and CNR between all protocols. In conclusion, our results demonstrated that the SNR and CNR have not risen proportionately with contrast agent contents. We hope that these results presented in this paper will contribute to decide contrast agent contents for brain MRI.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 G
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• pp.2809-2811
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• 1999

In this paper, we develope an algorithm to calculate field inhomogeneity in MR imaging using a dual fast spin echo pulse sequence. Because phase modulation time can be easily modified with this pulse sequence, high resolution image can be obtained and acquisition time can be reduced compared to gradient echo technique. In the case of phase wrapping in field map, phase corrected using image processing technique. We assume the field pattern to be second order polynomial and apply Pseudo-Inverse equation to calculate second order polynomial coefficients. These coefficients can be used for the shimming of the magnetic field.

• Investigative Magnetic Resonance Imaging
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• 제24권1호
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• pp.21-29
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• 2020

Purpose: To investigate normal location of the peroneus longus tendon (PL) in the cuboid groove by evaluating it between ankles with no significant abnormality (asymptomatic group) and those with retromalleolar PL dislocation (dislocation group) using three-dimensional isotropic fast spin-echo (3D-FSE) magnetic resonance imaging (MRI) of the ankle. Materials and Methods: Thirty-six and 32 3D-FSE ankle MRI were assigned to the asymptomatic group and the dislocation group, respectively. Using multiplanar reformatted 3D-FSE, qualitative PL location (i.e., outside, overlying, and inside in relation to the cuboid groove), quantitative PL location (i.e., distance between the proximal margins of PL and cuboid groove), and cuboid groove size were measured in lateral, middle, and medial levels of the cuboid groove. Results: In the asymptomatic group, 64%, 42%, and 11%, respectively, had the outside or overlying-located PL in lateral, middle, and medial levels of the cuboid groove and the quantitative location gradually decreased from lateral to medial level. Qualitative and quantitative PL locations were not significantly different between the asymptomatic group and dislocation group. Cuboid groove size showed significant negative correlation with quantitative PL location in both groups. Conclusion: Outside- or overlying-located PL in lateral and middle levels of the cuboid groove would be a normal finding, regardless of PL status at the retromalleolar level.

• Journal of Korean Neurosurgical Society
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• 제47권6호
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• pp.437-441
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• 2010

Objective : The precise intra- vs. extradural localization of aneurysms involving the paraclinoid internal carotid artery is critical for the evaluation of patients being considered for aneurysm surgery. The purpose of this study was to investigate the clinical usefulness of T2-weighted threedimensional (3-D) fast spin-echo (FSE) magnetic resonance (MR) imaging in the evaluation of unruptured paraclinoid aneurysms. Methods : Twenty-eight patients with unruptured cerebral aneurysms in their paraclinoid regions were prospectively evaluated using a T2- weighted 3-D FSE MR imaging technique with oblique coronal sections. The MR images were assessed for the location of the cerebral aneurysm in relation to the dural ring and other surrounding anatomic compartments, and were also compared with the surgical or angiographic findings. Results : All 28 aneurysms were identified by T2-weighted 3D FSE MR imaging, which showed the precise anatomic relationships in regards to the subarachnoid space and the surrounding anatomic structures. Consequently, 13 aneurysms were determined to be intradural and the other 15 were deemed extradural as they were confined to the cavernous sinus. Of the 13 aneurysms with intradural locations, three superior hypophyseal artery aneurysms were found to be situated intradurally upon operation. Conclusion : High-resolution T2-weighted 3-D FSE MR imaging is capable of confirming whether a cerebral aneurysm at the paraclinoid region is intradural or extradural, because of the MR imaging's high spatial resolution. The images may help in identifying patients with intradural aneurysms who require treatment, and they also can provide valuable information in the treatment plan for paraclinoid aneurysms.

• 대한방사선기술학회지:방사선기술과학
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• 제27권4호
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• pp.17-21
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• 2004

최근 의학 영상 기술의 발전과 함께 동적 골반 MRI(Pelvic magnetic resonance imaging)가 소개되었고 이러한 기술을 이용하여 동적 MR 배변조영술이 소개되어 환자의 진단에 도움을 주기 위해 사용되고 있다. 처음에 도입 당시에는 탈장(Enterocele)과 방광탈출증(Cystocele) 등을 진단하기 위하여 사용되었지만, 이후 장기의 탈출증(Prolapse), 또는 다른 골반 장기의 이상에 점점 그 유용성이 증명되어 현재는 기능성변비 등 다른 질환에서도 많은 보고가 있다. 본 논고에서는 골반 MRI 및 동적 MR 배변조영술에 대해서 소개하고 앞으로의 임상적 응용에 대한 전망을 살펴보도록 한다. 최근까지도 Pelvic MRI의 결과들은 앙와위(Supine position)에서 골반의 움직임을 관찰하는데 Yang 등은 26명의 골반 기관의 탈출증(Pelvic organ prolapse)을 가진 환자들을 관찰하고 Pubococcygeal line을 해부학적인 지표로 이용하여 좋은 결과를 얻었다고 보고했다. 이들은 Fast gradient recalled acquisition(fast GRASS)을 이용하여, Cystocoele, Prolapse, Enterocoele 그리고 Rectocoele 등을 증상이 없는 대조군과 비교하여 보고하였다. Kruyt 등은 Posterior compartment를 주로 관찰하여 MRI가 Fluoroscopy에 비하여 더 도움이 된다고 보고하였다. Healy 등은 Fast GRASS sequence를 이용하여 변비를 가진 환자와 변실금을 가진 환자, 그리고 증상이 없는 대조군을 대상으로 하여 동적 MRI 검사를 실시하였다. 이들은 변비나 변실금 증상과 관련되어 환자들의 Posterior compartment에 여러 곳에서 Prolapse을 관찰할 수 있었다. 이후 MRI 기술은 Lienemann 등에 의해서 더욱 발전했는데 그는 Fast T2 weighted turbo spin echo 기술을 이용하여 영상을 좀더 세밀하게 얻을 수 있게 되었다. 지금까지의 앙와위에서의 검사로 진단에 한계가 있었던 Intussusception 등의 질환을 Open MR 등의 방법으로 극복할 수 있다면 장래에는 방사선학적 배변조영술을 대체할 수 있는 검사법으로 발전할 수 있을 것으로 생각된다.

• Investigative Magnetic Resonance Imaging
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• 제26권2호
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• pp.117-124
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• 2022

Purpose: In this study, we provide a way to assess even a slight effect of exercise on trunk-muscle activity. Materials and Methods: Seven healthy male participants (mean age, 24.7 ± 3.2 years; height, 171.2 ± 9.8 cm; and weight, 63.8 ± 11.9 kg) performed 15 sets of an exercise with 20 repetitions of 90° hip and right-knee flexion while lying supine. The exercise intensity was measured using the 10-point Rating of Perceived Exertion Scale after the first and 15th sets of exercises. Although cross-sectional areas and functional T2 mapping using ultrafast imaging (fast-acquired muscle functional magnetic resonance imaging, fast-mfMRI) have been proposed for imaging to evaluate exercise-induced muscle activity in real time, no previous studies have reported on the evaluation of trunk-muscle activity using functional T2 mapping. As a method for assessing trunk-muscle activity, we compared functional T2 mapping using ultrafast imaging (fast-mfMRI) with cross-sectional areas. Results: Although the muscle cross-sectional areas were increased by the exercise, there was no significant difference at rest. On the other hand, for all sets, the changes in T2 were significant compared with those at rest (P < 0.01). These results demonstrate that T2, calculated from fast-mfMRI images can be used to detect even a small amount of muscle activity induced by acute exercise, which was impossible to do with cross-sectional areas. Conclusion: Fast-mfMRI, which can also display functional information with detailed forms, enabled non-invasive real-time imaging for identifying and evaluating the degree of deep trunk-muscle activity induced by exercise.