• 한국컴퓨터정보학회논문지
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• 제15권5호
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• pp.125-132
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• 2010

본 연구에서는 소프트웨어 제품을 개발하여 테스팅을 거친 후 사용자에게 인도하는 시기를 결정하는 방출문제에 대하여 연구 하였다. 방출문제의 분포는 소프트웨어의 결함을 제거하거나 수정 작업 중에도 새로운 결함이 발생될 가능성이 있는 무한고장수를 가진 비동질적인 포아송 과정에 기초하였다. 수명분포는 지수 족 분포와 비지수족 분포를 이용한 최적 방출시기에 관한 문제를 비교 제시하였다. 이러한 지수 및 비지수분포에 근거하여 소프트웨어 요구 신뢰도를 만족시키고 소프트웨어 개발 및 유지 총비용을 최소화 시키는 최적 소프트웨어 방출 정책에 대하여 논의 되었다. 본 논문의 수치적인 예에서는 고장 간격 시간 자료를 적용하고 모수추정 방법은 최우추정법을 이용하고 추세분석을 통하여 자료의 효율성을 입증한 후 최적 방출시기를 추정하였다.

• 초등상담연구
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• 제11권3호
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• pp.427-446
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• 2012

본 연구는 장애아동가족의 스트레스가 문제해결능력에 미치는 영향에 대해 가족탄력성의 조절효과를 알아보고자 하였다. 연구대상자는 총 546명으로 특수학교에 재학 중인 유치원, 초 중 고등학교의 부모를 대상으로 설문조사를 실시하였다. 수집된 자료는 조사대상자의 스트레스, 문제해결능력, 가족탄력성의 특성을 알아보기 위해 기술적 분석과 상관관계, 그리고 조절 효과를 검증하기 위해 위계적 회귀분석을 실시하였다. 연구결과는 다음과 같다. 첫째, 장애아동가족의 스트레스, 문제해결능력, 가족탄력성 간의 유의한 상관관계가 있는 것으로 나타났다. 둘째, 장애아동가족의 스트레스와 문제해결능력의 관계에서 가족탄력성의 조절효과가 확인되었다. 즉, 가족탄력성의 신념체계와 의사소통과정은 스트레스와 문제해결능력에서 조절효과가 있는 것으로 밝혀졌다. 이는 가족탄력성이 높을수록 스트레스는 낮아지고 문제해결능력은 높아진다는 것을 의미한다고 볼 수 있다. 따라서 장애아동가족이 스트레스를 낮추고 문제해결능력을 향상시킬 수 있도록 학교현장 및 지역사회에서는 장애아동가족의 가족탄력성을 높일 수 있는 가족상담 및 부모상담, 가족탄력성 프로그램의 개발 및 지원이 필요하다고 본다.

• 대한가정학회지
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• 제20권1호
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• pp.65-77
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• 1982

The intent of this study was to focus attention on the relationship between curtain fabrics and consumer perceptions towards curtains and draperies. This study consisted of the laboratory test for thermal transmittance of selected fabrics and the exploratory survey for consumer perceptions towards curtains and draperies. The objectives of the laboratory test were to measure fabric's thermal transmittance, thickness, and count which affect to the effect in heat controlling. Selected 23 fabrics were tested at Korean Yarn and Fabrics Testing Inspection Institute. The objectives of the exploratory survey were to determine sociodemographic factors; the stage of family life cycle, the economics status, and homemaker's level of education, and physical factors; the type of houses, the direction of windows, and the type of windows, affect consumer perceptions toward curtains and draperies. Questionaires were administered to 489 homemakers selected by a stratified propotional sampling plan, in Seoul in October, 1981. Data from responses were analyzed by T-test(Analysis of Varience) and Partial Correlation. The major findings are as follows; 1. The results of the laboratory test 1) The fabrics used for draperies had higher effect in heat controlling than the fabrics used for glass curtains. 2) It did not show much differences among the fibers in heat controlling. The thicker fibers, however, had the higher effect in heat controlling among same fibers. 3) The fabrics which had high level of effect I heat controlling were corduroy, flax, rayon, nylon, acetate, thick polyester, and thick polyacrylic. The fabrics which had midium level of affect in heat controlling were velveteen, velvet, and thin polyester. The fabrics which had low level of effect in heat controlling were cotton, silk, and thin polyarcylic. 4) The draperies with lining showed 2∼5 times more effective in heat controlling than the draperies without lining. 2. The results of the exploratory survey Consumer perceptions towards curtains and draperies consisted of functional, financial, and aesthetic perception. 1) Factor affecting functional perception towards curtains and draperies was the stage of family life cycle. Families in the contracting stage considered function of curtains and draperies significantly better than those in others stages. 2) Factors affecting financial perception towards curtains and draperies were the economic status, homemaker's level of education, the direction of windows, and the type of windows. However the correlation between the factors and financial perception was too low to explain the significance of tendency. 3) There was not any factors affecting aesthetic perception towards curtains and draperies.

• 한국인구학
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• 제14권1호
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• pp.55-69
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• 1991

The objective of the study is to figure out the status of reproductive health and general characteristics related to maternal health for Korean-Americans living in Los Angeles. We collected data from the married women who wanted no more additional child birth and were attending the Family Planning Clinic of Koryo Health Foundation in Los Angeles during 1988. There were 494 women met the eligibility requirement for this study. The results are summarized below. 1. In the age distribution of the women who desired no more additional child birth, women 30-34 age group constituted the largest proportion at 36.6 percent ; the mean age of women was 35.1915.55. The mean number of child birth was 1.77, and the proportion of the women by number of child birth were 35.2 percent for one children, 50.1 percent for two children 10.5 percent for three children, and 2.6 percent for four children. All of the women experienced pregnancy at least once, and mean number of pregnancy was 3.42. The mean number of total experience of induced abortion was 1.56. and 76.7 percent of these women had experience with induced abortions. To prevent further pregnancies, 90.1 percent of the women were utilizing the contraceptive methods, and the highest proportion by the contraceptive methods was condoms(53.7%), 9.3 percent in spermicides, 8.7 percent in IUDs, 8.7 percent in rhythm method, and 6.9 percent in oral pills. 2. The mean age of women at each stage of reproductive life cycle were 14.74 years at time of menarche, 24.55 years at time of marriage, 26.60 years at time of the first child birth, and 28.75 years at time of the last child birth. In age distribution of the women by birth cohort (Group I : birth cohort 1940-1954, Group H : birth cohort 1955-1970), the mean menar-cheal age of the women was 14.96 years in group I , and 14.53 years in group H . Mean age at time of marriage was 25.01 years in group I and 24.08 years in group H . Mean child birth age of the women by birth cohort was 27.19 years In group I and 26.01 years in Group II for the first child birth and 30.07 years in group I and 27.45 years in group II for the last child birth. The total length of reproductive life cycle from menarche to menopause (presumed to be at 49 of age years) was 34.26 years. The len-gth of phase I (from menarche to marriage) was 9.81 years, while phase H (marriage to first birth) was 2.05 years, and phase Ill (first birth to last birth) was 2. 15 years, and the last phase of reproductive life cycle, phase IV (last birth to menopause) was 20.25 years. The proportion of each phase 10 total length of reproductive life cycle was 28.6 percent, 6.0 percent 6.3 percent, and 59.t percent respectively. In the tendency of each phase in reproductive life cycle by birth cohort (group I , U ), the length of phase I, II , III of birth cohort group II was diminished in comparison with those of birth cohort group I , but the length of phase IV was extended by 2.38 years. 3. Among the women, the mean number of total pregnancy by birth cohort group was 2.01 in group I and 1.10 in Group II, and mean number of child birth was 1.97 in group I and 1.58 in group II. In terms of pregnancy was-tage rate by birth cohort group, among the total pregnancy of birth cohort group I , 51.8 percent of the cases resulted in induced abortions or spontaneous abortions whils 48.2 percent resulted in live births, and 42.2 percent or total pregnancy in group II resulted in pregnancy wastage and 57.8 percent of the cases resulted in live births.

• 생명과학회지
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• 제25권1호
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• pp.1-7
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• 2015

칼슘 의존적으로 활성화되는 neutral protease calpain에 의한 단백질 분해는 세포의 성장을 조절하는데 중요한 단백질들의 역할에 매우 중요한 역할을 한다. Cyclin의 분해는 세포주기의 진행을 위한 필연적인 과정이다. D-type cyclins는 외부자극이나 신호에 의하여 세포주기의 G1 초기에 합성이 된 후 cyclin-dependent kinases (cdk4 및 cdk6)와의 결합하여 세포주기 S기 진입을 촉진하는 역할을 한다. 본 연구에서는 cyclin D3 단백질이 calpain protease에 의하여 번역 후 수준에서 조절 받고 있음을 제시하였다. 본 실험의 조건에서 lovastatin과 actinomycin D가 처리된 PC-3-M 전립선 암세포에서 cyclin D3 단백질의 발현이 완전히 사라졌지만, calpain inhibitor인 LLnL의 처리에 의하여 정상 수준으로 회복되었음을 알 수 있었다. 그러나 26S proteasome의 선택적 억제제인 lactacystin, lysosome 억제제인 ammonium chloride 및 chloroquine, serine protease 억제제인 PMSF는 동일 조건에서 lovastatin과 actinomycin D 처리에 의한 cyclin D3 단백질의 발현저하를 억제하지는 못하였다. In vitro 조건에서 순수 분리된 calpain은 cyclin D3 단백질을 칼슘 농도 의존적으로 분해하였으며, cyclin D3 단백질의 반감기는 LLnL 처리에 의하여 매우 유의적으로 증가되었다. 또한 calpain 저해인자인 calpastatin의 과발현은 PC-3-M 세포에서 뿐만 아니라 NIH 3T3 섬유아세포에서도 cyclin D3 단백질의 반감기 및 안전성을 증대시켰다. 이러한 결과는 cyclin D3 단백질이 칼슘에 의해 활성화 되는 protease calpain에 의해 조절됨을 보여주는 것이다.

• Journal of Mechanical Science and Technology
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• 제19권10호
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• pp.1919-1931
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• 2005

Human joint motion can be kinematically described in three planes, typically the frontal, sagittal, and transverse, and related to experimentally measured data. The selection of reference systems is a prerequisite for accurate kinematic analysis and resulting development of the equations of motion. Moreover, the development of analysis techniques for the minimization of errors, due to skin movement or body deformation, during experiments involving human locomotion is a critically important step, without which accurate results in this type of experiment are an impossibility. The traditional kinematic analysis method is the Angular-based method (ABM), which utilizes the Euler angle or the Bryant angle. However, this analysis method tends to increase cumulative errors due to skin movement. Therefore, the objective of this study was to propose a new kinematic analysis method, Position-based method (PBM), which directly applies position displacement data to represent locomotion. The PBM presented here was designed to minimize cumulative errors via considerations of angle changes and translational motion between markers occurring due to skin movements. In order to verify the efficacy and accuracy of the developed PBM, the mean value of joint dislocation at the knee during one gait cycle and the pattern of three dimensional translation motion of the tibiofemoral joint at the knee, in both flexion and extension, were accessed via ABM and via new method, PBM, with a Local Reference system (LRS) and Segmental Reference system (SRS), and then the data were compared between the two techniques. Our results indicate that the proposed PBM resulted in improved accuracy in terms of motion analysis, as compared to ABM, with the LRS and SRS.

• 생명과학회지
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• 제18권3호
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• pp.336-343
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• 2008

본 연구에서는 인체전립선 상피세포인 267B1 세포에서 HDAC 저해제인 TSA에 의한 증식억제가 apoptosis 유도에 의한 것임을 제시하였다. 이러한 TSA에 의한 267B1 세포의 apoptosis에는 c-IAP-1 및 c-IAP-2와 같은 IAP family의 발현감소가 동반되었으나 Bax 및 Bcl-2와 같은 Bcl-2 family의 발현에는 큰 변화가 없었다. 그리고 TSA에 의한 267Bl 세포의 apoptosis는 caspase의 활성에 의한 표적 단백질들의 분해와 연관성이 있었다. 또한 TSA에 의한 apoptosis 유도에서 $NF-{\kappa}B$의 활성이 증가된다는 것을 세포질에서 $NF-{\kappa}B$의 핵 내로의 이동에 따른 전사활성의 증가 현상에 의한 것임을 다양한 방법으로 제시하였다. 본 연구의 결과는 TSA와 같은 HDAC 저해제에 의한 apoptosis 유도에는 $NF-{\kappa}B$의 활성 증가가 동반될 수 있음을 보여주는 결과로서 HDAC 저해제의 항암활성에 대한 $NF-{\kappa}B$의 새로운 역할 가능성을 제시하여 주는 것으로서 이에 관한 추가적인 연구의 필요성을 제시하였다.

• 대한가정학회지
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• 제31권1호
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• pp.97-120
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• 1993

This study is designed to understand marital relationships of the rural couples in Korea. The primary purposes of this study are to examine the relationship between marital satisfaction and role evaluation of the spouse and to construct a path model in which shows the relationships among background variables, role evaluation of the spouse and marital satisfaction. Structured guestionnaires from 435 couples with school-age children and teenagers living in rural area are analyzed in this study. The major findings are as follows : 1. Factor analysis of the role evaluation of the spouse results I 4 factors for both husbands and wives; emotional support-sexual role child socialization-economic role, kinship role and housekeeping role. 2. The most important factor influencing the marital satisfaction is the role evaluation of the spouse o emotional support-sexual relation. While the number of children, and role evaluations of the spouse influence directly on the marital satisfaction of the wives, age, level of education, level of income and husband's occupation influence indirectly through role evaluations of the spouse on that of wives. 3. For husbands, family life cycle and their occupation influence indirectly on the marital satisfaction of the husbands and the marital satisfaction of them is also mediated by role evaluations of the wieves. Level of income of the family not only influences directly on marital satisfaction but influences on it indirectly. 4. Marital satisfaction is mediated by role evaluations of the spouse. The role evaluation of the spouse on emotional support-sexual relation has the most powerful effect on the marital satisfaction for both wives and husbands. About 60 percent of the variance in the marital satisfaction of rural couples can be explained by the role evaluation of the spouse. therefore, the result of the result of the study indicates that the role evaluation of the spouse on emotional support-sexual relation plays a significant part in determining the marital satisfaction of rural couples.

• 한국사회복지학
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• 제69권2호
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• pp.117-141
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• 2017

본 연구의 목적은 우울진입에 영향을 미치는 요인이 세대별로 어떤 차이가 있는지를 살펴보고 생애 주기별 우울 예방의 실천적 전략을 제시하는 것이다. 이를 위해 한국복지패널의 3~10차 조사 자료를 결합하여, 성년층과 중년층, 노년층의 우울진입 영향요인을 이산시간위험모델을 통해 분석하였다. 분석결과, 3세대 공통적으로 여자가 남자보다, 자아존중감이 낮을수록, 수입 만족도와 가족관계 만족도가 낮을수록 우울진입 가능성이 높았다. 또한 세대별로 차이를 나타낸 변수는 연령과 교육수준, 건강상태, 만성질환유무, 취업여부, 권역별지역, 여가생활 만족도였다. 성년(20~39세)의 경우 나이가 적을수록, 만성질환이 있는 경우에, 미취업자가 취업자보다 우울진입 가능성이 높다. 반면 중년층(40~64세)의 경우 나이가 많을수록, 건강상태가 좋지 않은 경우에, 만성질환이 없는 경우에, 여가생활 만족도가 낮은 경우에 우울진입 가능성이 높다. 마지막으로 노년층(65세 이상)은 교육수준이 높을수록, 건강상태가 좋지 않은 경우에, 도농 복합군이 서울보다, 여가생활 만족도가 낮을수록 우울진입 가능성이 높다. 이러한 결과를 바탕으로 우울진입을 예방하기 위해 세대별로 드러난 특성이 반영된 지원방안을 마련할 필요가 있음을 제시하였다.

• 한국주거학회논문집
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• 제10권2호
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• pp.223-234
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• 1999

The purpose of this study was to provide basic information for future residential flooring planning by identifying differences in preference for flooring materials of livingroom by characteristics of housewives living in apartment housing and by describing their perception of residential flooring materials and by analyzing their degree of satisfaction with the current flooring materials of livingroom. For this purpose, a survey was conducted by 281 housewives who lives in apartment, and analyzed by using frequency, percentage, mean, factor analysis, χ² test, t-test, one-way ANOVA and Duncan's Multiple Range test. The results of the study were obtained as follows: 1) The most preferred flooring materials was wood in the livingroom. Also, most of the reasons for preferred this flooring materials were good for health and good texture. 2) As a result of typifying housewives' perceptions of residential flooring materials, it was classified into fashoin-pursuit type, personality-expression type, beauty-pursuit type, health-pursuit type and practicality-pursuit type. 3) In the degree of satisfaction with the current flooring materials of livingroom, wood showed the highest level of satisfaction. 4) Differences in the degree of satisfaction with the current flooring materials of livingroom by personal characteristics of residents were analyzed. As results, it was found that the group who were later stage of family life cycle and experienced in replacing the flooring materials showed higher degree of satisfaction with the current flooring materials of livingroom.