• Title/Summary/Keyword: Family Composition

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A Frameshift Mutation causes Dentinogenesis Imperfecta Type II (상아질 형성부전증 제 II 형의 원인이 되는 Frameshift 돌연변이)

  • Hong, Jiwon;Shin, Teo Jeon;Hyun, Hong-Keun;Kim, Young-Jae;Lee, Sang-Hoon;Kim, Jung-Wook
    • Journal of the korean academy of Pediatric Dentistry
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    • v.44 no.2
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    • pp.164-169
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    • 2017
  • Dentinogenesis imperfecta type II (DGI-II) is an inherited disorder affecting the dentin matrix and is related to mutations in the dentin sialophosphoprotein (DSPP) gene. The protein encoded by the DSPP gene undergoes extensive posttranslational modifications. Dentin phosphoprotein (DPP), one of the DSPP expressed products, has unique composition with highly repetitive Asp-Ser-Ser amino acid residues and is related to the maturation of dentin mineralization. We aimed to identify mutation in DSPP, including the DPP coding region, contributing to inherited dentin defects in a Korean family with DGI-II. Clinical and radiographic examinations were performed, and all five exons and exon-intron boundaries of the DSPP gene were sequenced. Additionally, allele-specific cloning for highly repetitive DPP region was performed. By sequencing and cloning, a heterozygous single nucleotide deletion (c.2688delT) was identified. The identified mutation caused a frameshift in the DPP coding region. This frameshift mutation would introduce hydrophobic amino acids instead of hydrophilic amino acids and would result in a change in the characteristics of DPP.

Industrial Utilization and Function of Omega Fatty Acid and Their Content Variation in Perilla (들깨 오메가 지방산의 기능과 함량변이 및 이용)

  • Ryu Su Noh;Lee Seung Tack;Lee Jung Il;Lee Jae Hak
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.41 no.spc1
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    • pp.110-122
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    • 1996
  • The n-3 family fatty acids containing ${\alpha}$-linolenic acid(18:3, ALA) have been known as physiological activation materials such as inhibitory effects on the incidence of hyper-tension, coronary heart disease and cancers as well as the control of senilc dementia. Although a lot of ALA(about $63\%$) are contained in perilla oil, it has not been commercialized yet because the purification technique of the ALA has not been well established. The procedure of purification of ALA from perilla oil was saponified with 1 N-KOH /ethanol and then saturated and low level unsaturated fatty acids were removed by low-temperature crystallization method. The concentrated unsaturated fatty acids (containing about $75\%$ ALA) went down through the silver nitrate-impregnated silica column chromatography for separation of high purity of ALA. The results obtained we Fraction B, C and D contained ALA more than $85.5\%$(recovery, >$88.9\%,\;95.4\%$(recovery, >$54.4\%$) and $99.9\%$(recovery, >$31.5\%$) in purity, respectively. Seed oil content of the tested varieties were ranged from 34.8 to $54.1\%$ with $45.3\%$ of varietal means. The major omega fatty acids contained in the oil were oleic acid(n-9) $15.2\%$, linoleic acid(n-6) $13.9\%$ and linolenic acid(n-3) $63.1\%$ in the mean value. Varietal variation of n-9, 6 and 3 fatty acids ranged of $9.5\~21.4\%,\;9.1\~20.4\%$ and $50.6\~70.5\%$ respectively. Unsaturated fatty acid were averaged $92.2\%$ of seed oil in fatty acid composition. The ratios of n-6 to n-3 ranged of $0.13\~0.34\%$($0.22\%$ in mean value). The highest n-3 fatty acid variety was Yecheonjong being $70.5\%$. The lowest variety in ratios of n-6 to n-3 was Goseongjong being $0.13\%$. Oil content showed positive correlation with stearic acid and linolenic acid, while the negative correlation with oil content and linoleic acid. On the other hand, A significant negative correlation were showed between linolnic acid and the ratios n-6/n-3 fatty acid, saturated fatty acid. Saturated fatty acid was highly correlated with unsaturated fatty acid negatively being $r= -0.723^{**}$.

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BCTZ Addition on the Microstructure, Piezoelectric/Dielectric Properties and Phase Transition of NKLN-AS Piezoelectric Ceramics (BCTZ첨가가 NKLN-AS계 압전세라믹스의 미세구조와 압전/유전특성 및 상전이현상에 미치는 효과)

  • Lee, Woong-Jae;Ur, Soon-Chul;Lee, Young-Geun;Yoon, Man-Soon
    • Korean Journal of Materials Research
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    • v.22 no.1
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    • pp.35-41
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    • 2012
  • Presently, the most promising family of lead-free piezoelectric ceramics is based on $K_{0.5}Na_{0.5}NbO_3$(KNN). Lithium, silver and antimony co-doped KNN ceramics show high piezoelectric properties at room temperature, but often suffer from abnormal grain growth. In the present work, the $(Ba_{0.85}Ca_{0.15})(Ti_{0.88}Zr_{0.12})O_3$ component, which has relaxor ferroelectric characteristics, was doped to suppress the abnormal grain growth. To investigate this effect, Lead-Free $0.95(K_{0.5}Na_{0.5})_{0.95}Li_{0.05}NbO_3-(0.05-x)AgSbO_3-x(Ba_{0.85}Ca_{0.15})(Ti_{0.88}Zr_{0.12})O_3$[KNLN-AS-xBCTZ] piezoelectric ceramics were synthesized by ball mill and nanosized-milling processes in lead-Free $0.95(K_{0.5}Na_{0.5})_{0.95}Li_{0.05}NbO_3-(0.05-x)AgSbO_3$ in order to suppress the abnormal grain growth. The nanosized milling process of calcined powders enhanced the sintering density. The phase structure, microstructure, and ferroelectric and piezoelectric properties of the KNLN-AS ceramics were systematically investigated. XRD patterns for the doped and undoped samples showed perovskite phase while tetragonality was increased with increasing BCZT content, which increase was closely related to the decrease of TO-T. Dense and uniform microstructures were observed for all of the doped BCZT ceramics. After the addition of BCTZ, the tetragonal-cubic and orthorhombic-tetragonal phase transitions shifted to lower temperatures compared to those for the pure KNNL-AS. A coexistence of the orthorhombic and tetragonal phases was hence formed in the ceramics with x = 0.02 mol at room temperature, leading to a significant enhancement of the piezoelectric properties. For the composition with x = 0.02 mol, the piezoelectric properties showed optimum values of: $d_{33}$ = 185 pC/N, $k_P$ = 41%, $T_C=325^{\circ}C$, $T_{O-T}=-4^{\circ}C$.

Environmental Characteristics and Species Composition of Boehmeria platanifolia Habitat in South Korea (남한 개모시풀의 자생지 환경특성과 혼생식물종 분포)

  • Kim, Seong-Min;Shin, Dong-Il;Song, Hong-Seon;Yoon, Seong-Tak;Cho, Yong-Koo
    • Korean Journal of Medicinal Crop Science
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    • v.16 no.5
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    • pp.371-375
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    • 2008
  • This study was conducted to evaluate geographical distribution patterns of natural habitats, soil properties, and plant species grown with native Boehmeria platanifolia in South Korea. The relative density and coverage of Boehmeria platanifolia were 7.0% and 25.6% respectively. Most Boehmeria platanifolia were growing below 200 m of altitude, and they were rarely found at the higher altitude. Over 80% of Boehmeria platanifolia's habitats were found at below $20^{\circ}$ and their habitats were concentrated at the west and the north face slope rather than the south face slope. Nearly 90% of Boehmeria platanifolia were grown at little and middle light condition's area, and 69.1% of them were natively growing in humid soil in their natural habitats. Soil texture of their habitats were mostly clay loam and the soil pH was 6.2. The contents of soil organic matter was $24\;g\;kg^{?1}$ and $P_2O_5$ was $31\;mg\;kg^{?1}$. Plant species grown with native Boehmeria platanifolia were 60 family, 125 genus and 171 species. Clematis apiifolia showed the highest relative density and coverage among plant species grown with native Boehmeria platanifolia.

The Study on Hyo Consciousness and Filial Piety of Middle School Students (중학생의 효 의식과 효행에 관한 연구)

  • Lee Sook-Hee;Shin Hyo-Shik;Lee Seon-Jeong
    • Journal of Korean Home Economics Education Association
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    • v.17 no.2
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    • pp.159-170
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    • 2005
  • This Study has an aim to offer the basic materials to teach the establishment and practice of Hyo consciousness to teenagers after finding the degree of accomplishment about their filial piety as the changes of related variables for the subject of this study, the Middle school boys and girls. The results of this research were followings. 1. The objects of research's Hyo consciousness and filial piety was totally high. 2. The teenagers' Hyo consciousness was showed significant difference according to adolescent's sea school's place, parents' job, the level of parents' education, income level, religion, family composition, and the place people who were educated Hyo live. 3. The teenagers' filial piety was showed significant difference according to adolescent's sea mother's job, the level of father's education, religion, and the place people who were educated Hyo live. 4. The teenagers' filial piety was showed significant difference according to Hyo consciousness. 5. In the relative influence of changes of having influence on filial piety, the better relative changes for filial piety were expressed as sex, religion, the place people who were educated Hyo a lot live, and Hyo consciousness. That is, the more they had Hyo consciousness the more they practiced filial piety. and girl students was expressed higher than boy students in practicing.

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Modern Reproducing of Jehotang Method (제호탕(醍醐湯)의 현대적 재현)

  • JI, Myoung-Soon;Jeon, Won-Kyung;Ko, Byoung-Seob;Anh, Sang-Woo;Yoon, Chang-Yeol
    • The Journal of Korean Medical History
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    • v.21 no.1
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    • pp.59-69
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    • 2008
  • The "tang[tɑ:ŋ]" in Korean pronounciation means the beverage made of boiled medicinal herbs. The"Jeho-tang", the name of Drink in this abstract, is described in a variety of medical books including the "Dongeui Bogam" as being effective for illness from the summer heat in promoting digestion, curing the heatstroke and bringing it to a halt. The Drink was used as the Royal gifts granted to retainers and royal families on the Day of Dano-festival on the fifth of the fifth month of the year according to the lunar calendar, the items of encouragement for those who worked hard in sacrifices, and the awards for students of Confucianism who were proficient in their learning. The Jeho-tang used in this study was scientifically cooked again after a long time in history through looking at the methods written in the documents concerned with the Drink such as the "Dongeui Bogam" and the "Taste of Korea". In preparation of the medicinal herbs for the Drink, the powder of thinner than 30 mesh of the "Prunus mume", which is a species of Asian plum in the family of Rosaceae, and those of 50 mesh of the "Santalum album", which is the fragrant wood of trees in the genus Santalum and the "Amomum Xanthioides", which is produced in Vietnam and is the name of a kind of herb medicines, being very effective in the desease caused from heatstrare, were used. The sugar concentration of the honey boiled down long time at low heat was $82.43^{\circ}Bx$. When cooking in a double boiler, the inner part of the liquid for the Drink was kept at $80^{\circ}C$ for 12 hours to make it finished in a state of ointment. In the general composition of the finished Jeho-tang, the moisture content was 24.4%, 1.3% of crude fat, 1.4% crude protein and 0.7% ash, along with pH3.2. The acceptance on the whole was come out to be the highest in the sample diluted with the drinking water of 7-fold of the Jeho-tang, indicating that the 7-fold's addition of water was optimum level for drinking. In the Drink cooked by a vaccum pressure extractor for herb medicine, which was developed to improve the art of cooking, the longer the time of pressure was, the less the heterogeneous feeling at tongue was and the more the glossiness of the Drink was. The Jeho-tang cooked under pressure for 7 hours received an excellent evaluation in its acceptability in every way.

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The View on Childrearing of University Women (여대생의 자녀 양육관)

  • Kim, Young-Hee;Kim, Shin-Jeong
    • Women's Health Nursing
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    • v.6 no.2
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    • pp.269-290
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    • 2000
  • This study was conducted to inquire about the view on childrearing of university women for the purpose of building up the positive parent- child relationship and setting up preliminary parenting education program. The subjects were 137 university women who were freshmen to junior in one women's university in Seoul. Using the self-report questionnaire, data were collected from December in 1998 to March in 1999 and the contents which subjects wrote down were categorized by content analysis method. The results were as followed: 1. The age range of subjects were 20-22 years and main rearer was her mother(71.5%) 2. The view of subjects were revealed by 374 statements and then tied together 34 themes: 'exemplary parent model as a guider'(8.6%), 'determination for oneself' (8.0%), 'expression of love'(6.2%), 'humanity education'(4.8%), 'carrot and stick'(4.5%), 'respect of personality'(4.3%), 'sound living habit'(4.1%), 'conversation'(3.7%), 'regulation of greediness' (3.7%), 'supply of live experience'(3.7%), 'supply of broad and substantial vision'(3.5%), 'free choice'(3.5%), 'broad-mindedness'(3.5%), 'consideration'(3.0%), 'doing together'(3.0%), 'propriety education' (2.4%), 'pursuit of naturalness'(2.4%), 'looking for one's life'(2.4%), 'confidence'(2.1%), 'rearing by oneself'(2.1%), 'encouragement'(2.1%), 'cultivation of right sexual senses'(2.1%), 'desirable home environment'(1.9%), 'doing one's best'(1.9%), 'understanding'(1.6%), 'psychological intimacy'(1.6%), 'treat fair'(1.6%), 'pursuit of physical, psychological health' (1.6%), 'concerning'(1.3%), 'religious life'(1.3%), 'respect of individuality'(1.3%), 'cooperation' (1.1%), 'often-minded family'(0.8%), 'positive attitude'(0.8%). 34 themes were categorized by 12 categories once more: 'mature parenthood'(15.5%), 'acceptance' (11.5%), 'autonomy'(11.5%), 'pursuit of healthy life style'(9.4%), 'eagerness'(9.1%), 'making efforts'(8.8%), 'education'(8.8%), 'emotional bonding' (7.8%), 'respect'(7.2%), 'corporal punishment' (4.5%), 'supporting'(3.2%), 'composition of environment'(2.7%). In conclusion, we could expect that university women had a democratic view on childrearing with love and autonomy for a base. So we need to offer them nursing implementations such as preliminary parenting programs and parenting consulting in order to promote positive and interactional parent-child relationship by strengthening their desirable view on childrearing.

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Antioxidant, Inhibitory on NO Production and In-vitro Cell Regeneration Effects of Pink-aloe (핑크-알로에의 항산화, NO 생성 억제 및 세포 재생 효과)

  • Lee, Kyung Ju;Jang, Wookju;Kim, You Ah;Park, Byoung Jun;Kang, Hakhee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.46 no.3
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    • pp.273-282
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    • 2020
  • Aloe vera (Aloe barbadensis Miller) has been used since ancient times to improve various skin diseases such as burns, wounds, and eczema. It has been reported that Aloe vera contains vitamin, enzyme, mineral, sugar, phenolic compound, fatty acid and amino acid. Aloe vera changes its color from green to red under the extreme thermal and arid climate to protect itself. These morphological changes induce variation of composition such as increasing of aloe-emodin content. Aloe-emodin is one of the major anthraquinone in aloe family plants. Since aloe-emodin contains a polyphenolic structure, this compound may be responsible for the reported antioxidant and anti-inflammatory effects of aloe. However, there is no research on the process of increasing the compounds of Aloe vera. Therefore, the purpose of this study is to develop a pink aloe manufacturing process that increases the aloe-emodin content and enhances the antioxidant and anti-inflammatory activities of aloe. As a result of heating aloe under appropriate conditions, pink aloe increased aloe-emodin content compared to general aloe, and exhibited effects such as increasing antioxidant activity, inhibiting NO production, and promoting cell regeneration. Through this study, the applicability of pink aloe as a new anti-aging material in the cosmetic field was confirmed.

Fish Assemblages by SCUBA Observations in the Water off Tongyeong, Korea (잠수관찰을 통한 경남 통영 연안의 어류상)

  • Gwak, Woo-Seok;Lee, Seung-Hwan;Lee, Yong-Deuk
    • Korean Journal of Ichthyology
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    • v.28 no.2
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    • pp.100-109
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    • 2016
  • Species composition and distribution characteristics of fish were determined by monthly underwater visual census from September. 2013 to August, 2014 at Yeongunri off Tongyeong, Korea. The study area was divided into five habitat types by depth and substrate: (1) sand bottom as depth of 0~2 m, (2) seagrass bed of 2~5 m, (3) rocky outcrop of 0~2 m, (4) rocky bottom of 2~5 m, (5) sandy mud bottom of 5~8 m. A total of 1,673 individuals belonging to 43 species in 26 families were recorded during the study period. The number of species tended to decrease after October, 2013 and increase from March, 2014 showing the highest number in October (autumn), and lowest in January (winter). In terms of the number of species, Gobiidae was the most dominant family (7 species), followed by Scorpaenidae (4 species). Embiotocidae was the most abundant (26.1% in total number of individuals), followed by Scorpaenidae (19.9%) and Gobiidae (19.3%). The dominant species were Sebastes inermis (19.2%), Ditrema temminckii (13.1%), and Neoditrema ransonnetii (12.9%). The number of species and abundance were relatively high at the depth between 2 and 5 m on seagrass bed and rocky bottom, whereas they were lower at the depth between 0 and 2 m on the sand bottom, suggesting that seagrass beds and rocky bottoms provided the diverse habitats for various fish species in this sea.

A Study on the Spatial Structure of the rural Dwelling Houses of China's Korean Ethnic - Based on Investigating and analyzing each District's rural Dwelling houses of China's Three Northeastern Provinces - (조선족 농촌주거 공간구성형태의 지역적 특징에 관한 연구 - 중국 동북3성 각 지역의 조선족 농촌주거에 대한 조사연구를 중심으로 -)

  • Jin, Ri-Xue;Park, Yong-Hwan
    • Journal of Korean Society of Rural Planning
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    • v.15 no.4
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    • pp.75-87
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    • 2009
  • This paper tries to explore the local uniqueness and evolutionary characteristics of the spatial structure of the rural dwelling houses of China's Korean Ethnic. For this purpose, the paper selected 51 typical samples in each district, analyzing their ancestral home, building age, size, construction method, family composition etc. Moreover, the paper classified the pattern of the samples and analyzed the characteristic and evolutionary process of each pattern. Conclusions based on the analysis of the ancestral homes are as follows: 1.The house pattern of these China's Korean ethnics who are originally from the Hamkyung province is mainly jeongji- access type (A-type). A-type is mainly distributed along the Tumen River and Yalu River, in the Sino-Russian borders and the inland areas of Heilongjiang province. With the migration of the China's Korean ethnics, in Sino-Russian borders and the inland areas of Heilongjiang province, A-type with the 'badang' space, vestibule-access type (C-type) and living-centered type (D-type) appeared. 2. House patterns of Korean ethnics who are originally from the Pyongan province include three types: A-type, kitchen type (B-type) and C-type. A-type is mainly distributed along the Yalu River while B-type and C-type are mainly in the inland areas of these three Northeast provinces. With the decrease of population, the merger of rooms happened in A-type; while in the B-type and C-type, bathroom and storage came to exist in the north of the room. 3. The house pattern of Korean ethnics who are originally from the Gyeongsang province is mainly B-type, which is distributed in the inland areas of Heilongjiang and Jilin provinces. Besides, C-type and D-type also exist. They are in Jilin and Liaoning provinces. In the process of evolution, storage was set in the north part of the room or the window was cancelled in order to defend the coldness in Heilongjiang area, while in Jilin and Liaoning provinces, living room came into existence, which is gradually developing to D-type.