• Bulletin of the Korean Chemical Society
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• 제33권6호
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• pp.1885-1889
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• 2012

Among 23 cytochrome P450s, CYP125A4 was proposed as a putative monooxygenase based on the high level of amino acid sequence homology (54% identity and 75% similarity) with the well characterized C27-steroid $Mycobacterium$ $tuberculosis$ CYP125A1. Utilizing MTBCYP125A1 as a template, homology modeling of SPCYP125A4 was conducted by Accelrys Discovery Studio 3.1 software. The modeled SPCYP125A4 structure with lowest energy value was subsequently assessed for its stereochemical quality and side-chain environment. The final model was generated by showing its active site through the molecular dynamics. The docking of steroids showed broad specificity of SPCYP125A4 with different orientation of ligand within active site facing the heme. One poses of C27-steroid with C26 facing the heme with distance of 3.734 ${\AA}$ from the Fe were predominant.

• Journal of Microbiology and Biotechnology
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• 제22권7호
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• pp.917-922
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• 2012

Homology modeling of Streptomyces peucetius CYP147F1 was constructed using three cytochrome P450 structures, CYP107L1, CYPVdh, and CYPeryF, as templates. The lowest energy SPCYP147F1 model was then assessed for stereochemical quality and side-chain environment by Accelrys Discovery Studio 3.1 software. Further activesite optimization of the SPCYP147F1 was performed by molecular dynamics to generate the final SPCYP147F1 model. The substrate limonene was then docked into the model. The model-limonene complex was used to validate the active-site architecture, and functionally important residues within the substrate recognition site were identified by subsequent characterization of the secondary structure. The docking of limonene suggested that SPCYP147F1 would have broad specificity with the ligand based on the two different orientations of limonene within the active site facing to the heme. Limonene with C7 facing the heme with distance of $3.4{\AA}$ from the Fe was predominant.

• 대한기계학회논문집B
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• 제26권4호
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• pp.578-586
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• 2002

Flow structures around a rectangular prism have been investigated by using a PIV(Particle Image Velocimetry) technique. A thick turbulent boundary layer was generated by using spires arid roughness elements. The boundary layer thickness, displacement thickness and momentum thickness were 650mm, 117.4mm and 78mm, respectively. The ratio between the model height(40mm) and the boundary layer thickness H/$\delta$, was 0.06. The Reynolds number based on the free stream velocity and the height of the model was 7.9$\times$10$^3$. The PIV measurements were performed at three different wall normal planes. Three recirculation regions at forward facing step, top of the roof and backward facing step are clearly seen and show three dimensional features. Dramatic changes of flow patterns are observed in the wake regions in the different spanwise wall normal planes. Instead of reattachment and recirculation zone, rising streamlines are depicted at the normal planes near the side wall due to the interaction with a rising horse shoe vortex. The peak of turbulent kinetic energy occurs at the separation bubble on top of the roof and the magnitude is 2.5 times higher compared with that of the wake region.

• Composites Research
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• 제16권3호
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• pp.18-24
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• 2003

샌드위치 구조물들은 적은 무게의 첨가로 높은 강성(stiffness)을 요구하는 조선업에 널리 사용되어져 왔다. 국부하중 조건 하에서 샌드위치 구조물에 대한 디자인 변수들을 고려하는 것은 중요시되어졌다. 이 연구는 샌드위치 보의 강도에 대한 core층의 밀도, core층의 두께 그리고 face층의 두께 비율의 영향을 기술하였다. 이차원 탄성이론에 바탕을 둔 파손 하중은 AS4/3501-6 facing과 polyurethane foam core 샌드위치 보의 3점 굴곡 실험 결과와 잘 일치 하였다. 또한 그러한 파손 하중들은 face층의 비율의 변화와 함께 비교되었다. 파괴 mode들의 교차점으로 결정되어진 최적조건은 강도(strength)와 강성(stiffness)에 대한 샌드위치 빔의 최적 core 밀도의 값이 결정되었다. 추가적으로 강도에 대한 최적조건과 그렇지 못한 샌드위치 보에 대한 face 두께 비율 효과가 하중 길이에 따라 비교되었으며, 강도와 강성이 core/face무게 비율과 항께 검토하였다.

• Corrosion Science and Technology
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• 제21권2호
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• pp.130-137
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• 2022

In this work, the degradation of high-pressure superheater tubes exposed to the flame of a duct burner in a heat recovery steam generator of a district heating system was evaluated. To assess the deterioration of the used superheater tube, the microstructure, microhardness, and tensile properties were investigated by comparison to an unused tube. The study found that a fin bound at the outer surface of the used tube became fragile only in the location facing the flame. This indicates that the tube was directly exposed to the flame from the duct burner or underwent abnormal overheating. While the unused tube showed a uniform value in hardness and equiaxial grain structure, the used tube revealed a decrease in hardness up to 105 HV and an increase in grain size with a plate-like morphology in the location facing the flame. The coarsening of the grain structure by the flame weakened the mechanical properties of yield strength, tensile strength, and elongation.

• 한국초전도ㆍ저온공학회논문지
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• 제9권1호
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• pp.22-26
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• 2007

Superconductor is weak in AC condition. Bifilar geometry provides a solution to reduce AC loss. Bifialr geometry is piled up or wound with more than two layers. When a layer of superconductor abuts on other layers, AC loss is affected by not only self-field, but also magnetic field induced by adjacent layers. In this study, two superconductors are piled up as a series connection so that current flows in different directions. By this method, magnetic field is cancelled. If magnetic field is cancelled, AC loss is reduced. To compare AC loss with respect to piling method, we measured the AC loss difference between the case facing each other with substrate side and the case facing with YBCO side. Measured AC loss is compared with one-way current flow single layer AC loss. In addition, we analyzed how much AC loss was increased, or reduced. All results were compared with those calculated with Norris equation. By this experiment, we concluded that distance between two wires is the important cause of AC loss. The distance between two wires affects magnetic field reduction in YBCO and induced current flow on substrate side.

• 제어로봇시스템학회논문지
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• 제15권4호
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• pp.445-450
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• 2009

This paper presents a new mobile robot localization method for indoor robot navigation. The method uses hexagon distributed color-coded patches on the ceiling and a camera is installed on the robot facing the ceiling to recognize these patches. The proposed "cell-coded map", with the use of only seven different kinds of color-coded landmarks distributed in hexagonal way, helps reduce the complexity of the landmark structure and the error of landmark recognition. This technique is applicable for navigation in an unlimited size of indoor space. The structure of the landmarks and the recognition method are introduced. And 2 rigid rules are also used to ensure the correctness of the recognition. Experimental results prove that the method is useful.

• 산업기술연구
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• 제35권
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• pp.47-53
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• 2015

Recent extreme weather events and natural disasters are causing rapid aging of the ancient structures with cultural value. It has threatened the safety and management. The construction design documents are not kept for such long time. Even if they are, they seem to be mismatched with the design structures due to corrosive effects. For these reasons, Korea has been facing difficulties in maintenance, reengineering and safety evaluation. In this study, three dimensional point cloud surface of bobsleigh is obtained using 3D LiDAR scanner. The obtained structure is compared with the original design and found to be highly accurate. The study shows the application of reverse engineering technique and its potential use for other civil structures.

• 한국정밀공학회지
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• 제16권5호통권98호
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• pp.74-82
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• 1999

To meet the needs of the hydraulic excavator of large capacity, tandem axial type piston pump which is high pressure and high speed have been developed. But inevitably we can not help facing the problem of noise at that time. In order to reduce the noise of this pump, many researchers have been studying the problem of oil distribution manner. But they are not interested in the symmetric structure of tandem type pump. So, focusing on the symmetric structure of tandem type pump, this paper analyzed unbalanced force developed in the pump chamber and verified the effect of the pumping phase of the piston on vibration and noise of the tandem axial type piston pump theoretically.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2006년도 추계 학술발표회
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• pp.241-255
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• 2006

Owing to a landslide or embankment damage be caused by a localized torrential downpour and heavy snowfall resulted from recent abnormal climate, a slope stability is very important. This study is investigate a general slope reinforcement method and applicability improvement of soil nailing method utilized prototype loading test for the facing stiffness effect confirmation. A prototype loading test supplements general slope stability study by numerical analysis or laboratory test with a resonable analysis of slope structure.