• 제목/요약/키워드: Facilitating Factor

검색결과 155건 처리시간 0.028초

Human ChlR1 Stimulates Endonuclease Activity of hFen1 Independently of ATPase Activity

  • Kim, Do-Hyung;Kim, Jeong-Hoon;Park, Byoung Chul;Lee, Do Hee;Cho, Sayeon;Park, Sung Goo
    • Bulletin of the Korean Chemical Society
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    • 제35권10호
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    • pp.3005-3008
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    • 2014
  • Human ChlR1 protein (hChlR1), a member of the cohesion establishment factor family, plays an important role in the segregation of sister chromatids for maintenance of genome integrity. We previously reported that hChlR1 interacts with hFen1 and stimulates its nuclease activity on the flap-structured DNA substrate covered with RPA. To elucidate the relationship between hChlR1 and Okazaki fragment processing, the effect of hChlR1 on in vitro nuclease activities of hFen1 and hDna2 was examined. Independent of ATPase activity, hChlR1 stimulated endonuclease activity of hFen1 but not that of hDna2. Our findings suggest that the acceleration of Okazaki fragment processing near cohesions may aid in reducing the size of the replication machinery, thereby facilitating its entry through the cohesin ring.

Factors Affecting the Behavioral Intention and Behavior of Using E-Wallets of Youth in Vietnam

  • PHAN, Trong Nhan;HO, Truc Vi;LE-HOANG, Phuong Viet
    • The Journal of Asian Finance, Economics and Business
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    • 제7권10호
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    • pp.295-302
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    • 2020
  • The study examines an empirical case that explores the key constructs of the Unified Theory of Acceptance and Use of Technology (UTAUT) (Venkatesh, Morris, Davis & Davis, 2003) and the relationship between security and privacy of the Theory of Perceived Risk (TPR) (Bauer, 1960). This study employs survey data of 200 young Internet users aged 18 to 25. The study was conducted through two steps: preliminary research by qualitative research method to form the official research scale then formal research by quantitative research method using CFA and SEM to test the research model. The research results show that performance expectancy and social influence significantly predict behavioral intention to use e-wallets in payment. In contrast, the factors, namely, security and privacy, and effort expectancy, are statistically insignificant on behavioral intention. Nevertheless, the facilitating conditions factor still affects the behavior of using e-wallets. The study proposes a model to generalize the online payment environment through the integration of UTAUT and TPR models that are important for online payment management and researchers in the technology environment. The findings of this study suggest that social influence significantly affects the intention of young people to use e-wallets instead of security and privacy.

협업기반 상황인지를 위한 u-Surveillance 다중센서 스테이션 개발 (Development of Multi-Sensor Station for u-Surveillance to Collaboration-Based Context Awareness)

  • 유준혁;김희철
    • 제어로봇시스템학회논문지
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    • 제18권8호
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    • pp.780-786
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    • 2012
  • Surveillance has become one of promising application areas of wireless sensor networks which allow for pervasive monitoring of concerned environmental phenomena by facilitating context awareness through sensor fusion. Existing systems that depend on a postmortem context analysis of sensor data on a centralized server expose several shortcomings, including a single point of failure, wasteful energy consumption due to unnecessary data transfer as well as deficiency of scalability. As an opposite direction, this paper proposes an energy-efficient distributed context-aware surveillance in which sensor nodes in the wireless sensor network collaborate with neighbors in a distributed manner to analyze and aware surrounding context. We design and implement multi-modal sensor stations for use as sensor nodes in our wireless sensor network implementing our distributed context awareness. This paper presents an initial experimental performance result of our proposed system. Results show that multi-modal sensor performance of our sensor station, a key enabling factor for distributed context awareness, is comparable to each independent sensor setting. They also show that its initial performance of context-awareness is satisfactory for a set of introductory surveillance scenarios in the current interim stage of our ongoing research.

산림경관과 치유 효과에 관한 국내문헌 고찰 (A Systematic Review on the Correlation between Forest Landscape and Therapeutic Effects)

  • 정필영;이주영
    • 한국환경과학회지
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    • 제30권7호
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    • pp.529-536
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    • 2021
  • The forest landscape has been considered to be one of the most beneficial factors, in regard to facilitating the therapeutic effects of the forest environment. The aim of this study was to review the preceding literary works on the correlation between forest landscape and its therapeutic effects and to ponder on key factors of forest landscape that promotes therapeutic results on people's psychological and physiological responses. Literature found in domestic research databases was analyzed and examined in accordance with the 'Preferred reporting items for systematic reviews and meta-analyses(PRISMA)' process. Six papers out of 1,890 were selected as key literature to support the connection. The quality of forest landscape was found to be an integral environmental factor in determining the healing effects of forests. In particular, several factors, including forest types, aquatic elements within the forest landscape, forest-use density and aesthetic elements of forest landscape were found to be crucial for enhancing the therapeutic effects on people's wellbeing. Despite the limited sample groups in the analyzed literature, the results offered a significant insight in supporting the healing effects of forests. Further studies on this subject are required to provide more scientific data for verifying the quality of the therapeutic effects of forests.

Factors Affecting Acceptance and Use of E-Tax Services among Medium Taxpayers in Phnom Penh, Cambodia

  • ANN, Samnang;DAENGDEJ, Jirapun;VONGURAI, Rawin
    • The Journal of Asian Finance, Economics and Business
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    • 제8권7호
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    • pp.79-90
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    • 2021
  • The purpose of this research is to identify factors affecting the acceptance and use of e-tax services among medium taxpayers in Phnom Penh, Cambodia. The researcher conducted the study based on a quantitative approach by using multi-stage sampling method, which selects a sample size by two or more stages. The first stage sampling was the stratified random sampling and the subsequent stage was purposive sampling. In this study, the stratified random sampling was first used, followed by purposive sampling. The data were collected from 450 medium taxpayers who experienced using e-tax services located in three tax branches in Phnom Penh. This study adapted the confirmatory factor analysis (CFA) and structural equation model (SEM) to analyze the model accuracy, reliability and influence of various variables. The primary result showed that behavioral intention has a significant effect on user behavior of e-tax services among medium taxpayers in Phnom Penh, Cambodia. Moreover, the results revealed that performance expectancy, effort expectancy, social influence, and anxiety have significant impact on behavioral intention. In addition, social influence has the strongest impact on behavioral intention, followed by anxiety, performance expectancy and effort expectancy. Conversely, facilitating conditions, trust in government, and trust in internet do not influence behavioral intention.

Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2

  • Choi, Jeongsuk;Buyannemekh, Dolgorsuren;Nham, Sang-Uk
    • Molecules and Cells
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    • 제43권12호
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    • pp.1023-1034
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    • 2020
  • Complement fragment iC3b serves as a major opsonin for facilitating phagocytosis via its interaction with complement receptors CR3 and CR4, also known by their leukocyte integrin family names, αMβ2 and αXβ2, respectively. Although there is general agreement that iC3b binds to the αM and αX I-domains of the respective β2-integrins, much less is known regarding the regions of iC3b contributing to the αX I-domain binding. In this study, using recombinant αX I-domain, as well as recombinant fragments of iC3b as candidate binding partners, we have identified two distinct binding moieties of iC3b for the αX I-domain. They are the C3 convertase-generated N-terminal segment of the C3b α'-chain (α'NT) and the factor I cleavage-generated N-terminal segment in the CUBf region of α-chain. Additionally, we have found that the CUBf segment is a novel binding moiety of iC3b for the αM I-domain. The CUBf segment shows about a 2-fold higher binding activity than the α'NT for αX I-domain. We also have shown the involvement of crucial acidic residues on the iC3b side of the interface and basic residues on the I-domain side.

Acceptance and Use of Mobile Banking in Central Asia: Evidence from Modified UTAUT Model

  • IVANOVA, Aisena;KIM, Ju Yeon
    • The Journal of Asian Finance, Economics and Business
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    • 제9권2호
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    • pp.217-227
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    • 2022
  • The main purpose of this study is to analyze the adoption and use of mobile banking by university students and its potential determining factors. This study comprises 259 completed questionnaires answered through an online survey method. The respondents are Mongolian university students who have experience in using mobile banking applications. Young adults rely heavily on technology and are more likely to adopt mobile banking applications; however, there is limited research on the acceptance and use of mobile banking applications among this cohort, particularly from the perspective of Central Asian developing economies. Through using the SmartPLS 3.3 software, confirmatory factor analysis was conducted to evaluate the construct and structural equation modeling. The main results indicate that performance expectancy, effort expectancy, social influence, and facilitating conditions are the main constructs related to mobile banking technology acceptance; perceived security positively impacts perceived trust. Moreover, perceived trust is the construct of the use of mobile banking technology by the university students who responded to the questionnaire. However, the relationship between perceived risk and use behavior was not accepted.

Determining Behavioral Intention of Logistic and Distribution Firms to Use Electric Vehicles in Thailand

  • Somsit DUANGEKANONG
    • 유통과학연구
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    • 제21권5호
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    • pp.31-41
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    • 2023
  • Purpose: Electric vehicle (EV) technology started in 2015 in Thailand. The Thai Government has indicated that 30% of all cars produced in Thailand by 2025 will be EVs. Using EVs in Thailand will reduce road pollution and increase energy efficiency, especially in major cities. Hence, the adoption of EVs in the country has been promoted. This study pointed out that social influence, facilitating conditions, perceived enjoyment, environmental concern, attitude, and perceived behavioral control are key factors affecting the behavioral intention to adopt EVs among logistic and distribution firms in Thailand. Research design, data, and methodology: 500 top management, middle management and purchasing managers of logistic and distribution firms in Thailand are surveyed. The study employed judgmental, convenience, and snowball sampling. Confirmatory Factor Analysis (CFA) and Structural Equation Model (SEM) are the main statistical tools for data analysis. Results: The results show that all determinants impact customers' willingness to adopt EVs, except perceived enjoyment and environmental control. Conclusions: The study proposes to promote the incentives by decreasing electricity prices and endorsing EVs purchase to accelerate the adoption of EVs in Thailand. Therefore, future policies should focus on behavioral intention toward EVs amongst logistic and distribution firms for enhancing the future of mobility in Thailand.

The Effect of Sports Club Membership Lifestyle on Choice Behavior

  • Sunmun Park;Shuo LI
    • International Journal of Advanced Culture Technology
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    • 제11권2호
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    • pp.267-275
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    • 2023
  • The purpose of this study is to investigate the influence of sports center members' lifestyles on participation promotion and choice behavior. To this end, more specifically, we intend to establish and clarify a hypothetical model based on the preceding studies of facilitating factors and factors that continue to participate according to the lifestyle of sports center members. In order to achieve this research purpose, the study subjects were set as the population of male and female adults over 20 who are using sports centers in Gwangju Metropolitan City and Jeollanam-do in 2021. As for the sampling method, the sample was extracted using cluster random sampling, and 300 people were used for the actual analysis, excluding 60 copies of double-entry and insincere or unreliable questionnaires. The survey tool was modified and supplemented according to this study based on the questionnaire that had been verified for reliability and validity in previous studies, and all questionnaire items were composed of a 5-point scale. The statistical analysis used for data analysis was frequency analysis, exploratory factor analysis, reliability analysis, and multiple regression analysis using SPSS Windows 21.0 Version. The conclusions obtained in this study through data analysis by such methods and procedures are as follows. First, according to the lifestyle of sports center members, participation promotion factors were found to have a partial influence. Second, according to the lifestyle of sports center members, the selection behavior was found to have a partial influence. Third, it was found that the participation promotion factors of sports center members partially affected the choice behavior.

Determining Leadership Styles to Support Civil Servant Relocation: A Case Study of Indonesia's New Capital Plan

  • IRAWANTO, Dodi Wirawan;NOVIANTI, Khusnul Rofida;FANANI, Lutfi
    • The Journal of Asian Finance, Economics and Business
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    • 제10권1호
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    • pp.233-242
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    • 2023
  • This study intends to investigate the impact of leadership style on civil servants' (in 4 ministries representatives of the Indonesian government) readiness to change and relocate to the future capital of Indonesia (Ibu Kota Nusantara / IKN). The quantitative approach was used from the data survey from 62 high-level civil servant representatives using a questionnaire. The collected data was analyzed using the SPSS software and exploratory factor analysis (EFA). The findings also indicated that, out of the 12 indicators of leadership style measured in this study, persuasion and integration leadership style should be considered crucial and important factors in shaping supportive behavior in the context of readiness for change. Making the relocation process successful requires avoiding the type of initiation structure leadership style. The finding of this study reveals that to choose the best leaders, the Indonesian government is urged to use these two criteria (persuasion and integration leadership style), especially for those in charge of facilitating the relocation process to IKN. Additionally, to demonstrate their confidence and make full use of their resources, leaders who are in command must be able to anticipate that the relocation of civil servants would go smoothly with less risk.