• Journal of Food Hygiene and Safety
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• v.24 no.1
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• pp.12-18
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• 2009

This experiment was conducted to investigate the effect of wa-song (Orostachys japonicus A. Berger) extracts on the oxidative stability of edible oil. Wa-song was dried from hot air (HWE) and freeze (FWE), and then they were extracted by hot water. The different levels (0.1, 0.5 and 1.0 g/100 mL) of HWE and FWE were added to soybean oil and lard. The chromaticity of edible oils was generally increased with prolonged heating time and HWE was higher than FWE. The anisidine value showed significant increase during heating for 48hrs. After heating for 48 hrs, it was lower than control, except for HWE added sample of 0.5 and 1.0 g/100 mL, FWE added sample of 1.0 g/100 mL. In lard, it was lower in sample added wa-song extract than control. The acid value was not significant by added amount of wa-song. Its value in HWE added sample was lower than FWE, after heating for 48 hrs. POV was lower HWE than FWE, also. After heating for 24 hrs, TBA values in soybean oil containing HWE and FWE added sample was lower than control. In lard, its value in HWE and FWE added sample was lower than control during heating for $12{sim}48\;hrs$. Therefore, those results suggested that HWE has higher antioxidant activity than FWE added sample, and then oxidative stability of HWE in edible oil was more potential for lard during its heating.

• Biomedical Science Letters
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• v.10 no.1
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• pp.9-13
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• 2004

We have investigated the effects of hypha-water extracts (HWE), fruit body-water extracts (FWE) and cordycepin from Cordyceps militaris on serotonin release out of human platelets and human platelet aggregation. HWE and FWE inhibited the release of [$^3H$]-serotonin from human platelet stimulated by thrombin (2 U/ml) or collagen (20$\mu$g/ml) in a dose-dependent manner. Furthermore, cordycepin, a major component of Cordyceps militaris, inhibited the human platelet aggregation induced by collagen (10$\mu$g/ml) in a dose-dependent manner. These results suggest that cordycepin containing in HWE and FWE may inhibit the serotonin release by suppressing the collagen-induced human platelet aggregation. Accordingly, our data demonstrate that HWE and FWE containing much cordycepin might have antithrombotic and antimigrainous functions.

• Korean journal of food and cookery science
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• v.24 no.6
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• pp.748-756
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• 2008

This study was conducted to investigate the antioxidant activity of hot water extracts of wa-song (Orostachys japonicus A. Berger) dried using hot air (HWE) and frozen (FWE). Varying levels (0.1, 0.5 and 1.0 g/100 g) of HWE and FWE were added to soybean oil and lard. Chromaticity, anisidine value, acid value, peroxide value (POV) and thiobarbituric acid (TBA) value in oils were measured periodically during their storage for 28 days at $60^{\circ}C$. The chromaticity of edible oils showed a general increas with prolonged storage as well increasing levels of extracts. The anisidine value was not significantly increased during storage for 14 days, but was significantly increased after storage for 21 days in soybean oil and lard. The anisidine value of HWE on soybean oil was $12.60{\pm}0.92{\sim}13.82{\pm}0.68$ after storage for 28 days its value was lower than that of the control and buthylated hydroxy anisol (BHT). The antioxidant activity of HWE was found to be more effective than that of FWE. The acid value of HWE was significantly increased during storage from 14 to 21 days in soybean oil and from 7 to 14 days in lard. The antioxidant activity of FWE was particulary effective at the primary stage of the reaction system of lard storage. POV was highly increased during the storage periods between 7 and 14 days in soybean oil. The antioxidant activity in all the samples tested did not significantly increase after storage for 14 days, except when 0.1 g/ 100 g of FWE added to lard. TBA values of all the samples were lower than that of control and 0.02% BHT during their storage. The antioxidant activities of wa-song within the reaction system of oils were more effective in soybean oil than in lard.

• The Korean Journal of Applied Statistics
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• v.27 no.7
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• pp.1197-1205
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• 2014

Typical clinical dose development studies consist of the comparison of several doses of a drug with a placebo. The primary interest is to find therapeutic window that satisfying both efficacy and safety. In this paper, we propose nonparametric method for identifying effective and safe doses in linear placement using score function. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of proposed procedure are compared with previous methods.

• Defense and Technology
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• no.7 s.137
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• pp.68-75
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• 1990

지난 수년간 외국의 병기와 군사장비에 대한 시험 및 평가를 포함한 미 국방부의 2가지 프로그램은 국방관계 잡지와 신문등 매스컴의 주목을 받아왔다. 어느 나라의 방산업체에 조달을 맡길 것인가의 문제, 조달을 수행할 나라들이 제출한 계획의 수치, 그리고 미군의 타개책등이 국방성 관계자들에 의해 검토되어 왔으며, 해외로부터 방위장비를 구입할때 미국 방산업체에 미치는 영향등에 대해 면밀한 조사와 평가가 이루어져 왔다. 미 국방부의 이러한 노력은 외국산 병기평가(FWE)계획과 나토 장비류 비교시험(NCT) 계획으로, 뚜렷이 나타나고 있다. 이글은 FWE와 NCT에 대한 미 국방부의 시각을 밝히고, 이 두 프로그램에서 미 국방부가 조달 후 후보업체를 지명하는 방법에 대해 서술된 것으로, 외국 방산업체들에게 좋은 자료가 될 것으로 사료된다.

• Journal of Korean Society of Forest Science
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• v.103 no.3
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• pp.503-509
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• 2014

The purpose of this study was to investigate the effect of Forest-walking exercise on gait pattern in the elderly. The subjects (n=37) were assigned to 2 groups: Forest-walking exercise (FWE) group (n=19, $66.34{\pm}4.31$ years old) and In-door treadmill-walking exercise (ITWE) group (n=18, $67.18{\pm}2.78$ years old). The subjects participated in FWE program or ITWE program (3 times/week, 80 min/day) for 12 weeks. The subjects were tested on functional fitness (strength, endurance, agility/balance, BMI) and gait pattern (cadence, velocity, and stability) at the beginning and the end of the 12-weeks program. For data analysis, mean and standard deviation scores were calculated, and independent t-test and repeated two-way ANOVA were used. The results of this study were as follow: First, FWE group was significantly more improved than ITWE group on functional fitness(lower-body muscular strength, lower-body flexibility, mobility, cardiorespiratory endurance) after 12-weeks exercise program. But both groups showed equally improvements on functional fitness (upper-body muscular strength, upper-body flexibility, BMI). Second, FWE group was significantly more improved than ITWE group on cadence, gait velocity, and gait stability after 12-weeks exercise program. Therefore, this study may suggest that Forest-walking exercise based on sensory-motor functional integration improves efficiently functional fitness and gait pattern in the elderly, and further becomes an effective exercise method that makes more dynamic life, and prevents from falling.

• Communications for Statistical Applications and Methods
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• v.19 no.1
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• pp.33-45
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• 2012

The primary interest of drug development studies is to estimate the smallest dose that shows a significant difference from the zero-dose control. The smallest dose is called the Minimum Effective dose(MED). In this paper, we suggest a nonparametric procedure to simultaneously find the MED of each group based on placements. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of the new procedures with those of discussed nonparametric tests to find MED.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.39 no.4
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• pp.303-311
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• 2013

This study was performed to investigate the anti-inflammatory activities of fermented Scutellaria baicalensis extracts using Lactobacillus rhamnosus. The extracts were WE (water extract at $100^{\circ}C$ for 24 h), EE (70% ethanol extract at $60^{\circ}C$ for 24 h), FWE (fermented and water extract at $60^{\circ}C$ for 24 h), FEE (fermented and 70% ethanol extract at $60^{\circ}C$ for 24 h). The cytotoxicity of the extracts was in the range of 11.2 ~ 15.6 % at 1.0 mg/mL concentratioin. The FEE showed the lowest activity at 1.0 mg/mL concentratioin. Compared to the WE, hyaluronidase inhibitory activity contents in the FEE increased to 9.2% at 1.0 mg/mL concentratioin. Nitric oxide production of WE, EE, FWE and FEE at 1.0 mg/mL concentration was mesured as 7.6, 7.9, 6.9, 6.4 ${\mu}M$, respectively. $PGE_2$ secretion of the human fibroblast of the FEE were lower than 810 pg/mL. Our results suggested that the extracts from fermentation process after 70% ethanol extraction had relatively high anti-inflammatory activities and that the Scutellaria baicalensis could be more extracted in FEE than others.

• Communications for Statistical Applications and Methods
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• v.9 no.3
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• pp.693-701
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• 2002

When the lowest dose level compared with zero-dose control has significant difference in effect, it is referred as minimum effective dose (MED). In this paper, we discuss several nonparametric methods for finding MED using updated rank at each sequential test step in small sample size and suggest new nonparametric procedures based on placement. Monte Carlo Simulation is adapted to compare power and Familywise Error Rate(FWE) of the new procedures with those of discussed nonparametric tests for finding MED.

• The Korean Journal of Applied Statistics
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• v.30 no.6
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• pp.1027-1036
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• 2017

Multiple comparisons are required to confirm whether or not something is significant if the null hypothesis to test whether the difference between more than three treatments is rejected in a one-way layout. There are both parametric multiple comparison method Tukey (1953) and Nonparametric multiple comparison method based on Kruskal-Wallis (1952).This procedure is applied to a mixed sample of all data and then an average ranking is used for each of three or more treatments. In this paper, a new nonparametric multiple comparison procedure based on joint placements for a one-way layout as extension of the joint placements described in Chung and Kim (2007) was proposed. Monte Carlo simulation is also adapted to compare the family wise error rate (FWE) and the power of the proposed method with previous methods.