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http://dx.doi.org/10.5351/CKSS.2002.9.3.693

Nonparametric Procedures for Finding Minimum Effective Dose in a One-Way Layout  

Kim, Hyeonjeong (Department of Biostatistics, The Catholic University of Korea)
Kim, Dongjae (Department of Biostatistics, The Catholic University of Korea)
Publication Information
Communications for Statistical Applications and Methods / v.9, no.3, 2002 , pp. 693-701 More about this Journal
Abstract
When the lowest dose level compared with zero-dose control has significant difference in effect, it is referred as minimum effective dose (MED). In this paper, we discuss several nonparametric methods for finding MED using updated rank at each sequential test step in small sample size and suggest new nonparametric procedures based on placement. Monte Carlo Simulation is adapted to compare power and Familywise Error Rate(FWE) of the new procedures with those of discussed nonparametric tests for finding MED.
Keywords
Minimum Effective Dose(MED); Nonparametric; Placement;
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