• Title/Summary/Keyword: FUNCTIONAL GROUPS

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Genomic Tree of Gene Contents Based on Functional Groups of KEGG Orthology

  • Kim Jin-Sik;Lee Sang-Yup
    • Journal of Microbiology and Biotechnology
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    • v.16 no.5
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    • pp.748-756
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    • 2006
  • We propose a genome-scale clustering approach to identify whole genome relationships using the functional groups given by the Kyoto Encyclopedia of Genes and Genomes Orthology (KO) database. The metabolic capabilities of each organism were defined by the number of genes in each functional category. The archaeal, bacterial, and eukaryotic genomes were compared by simultaneously applying a two-step clustering method, comprised of a self-organizing tree algorithm followed by unsupervised hierarchical clustering. The clustering results were consistent with various phenotypic characteristics of the organisms analyzed and, additionally, showed a different aspect of the relationship between genomes that have previously been established through rRNA-based comparisons. The proposed approach to collect and cluster the metabolic functional capabilities of organisms should make it a useful tool in predicting relationships among organisms.

Diagnostic Values of Tongue Coating Thickness and Sterno-costal Angle in Functional Dyspepsia (기능성 소화불량 환자에서 설태후박 및 흉늑각 측정의 진단적 가치)

  • Son, Ji-Young;Kim, Jin-Sung
    • The Journal of Internal Korean Medicine
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    • v.35 no.2
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    • pp.157-174
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    • 2014
  • Objectives : The aims of this study were to evaluate the diagnostic values of tongue coating thickness and sterno-costal angle as the quantitative diagnostic indicators in functional dyspepsia. Methods : We surveyed 60 functional dyspepsia patients recruited by the clinical trial, 'Clinical Trial for Evaluation on Availability of tongue diagnosis system (CTS-1000) : a Pilot study'. The patients were classified into three groups according to Rome III criteria for functional dyspepsia, and categorized into five groups according to Instrument of pattern identification for functional dyspepsia. Nepean dyspepsia index-Korean version (NDI-K) score, tongue coating thickness (percentage of tongue coating by tongue diagnosis system (CTS-1000), and weight of tongue coating by microbalance), sterno-costal angle, duration of illness and body mass index (BMI) were investigated. Results : Among the 5 types by instrument of pattern identification for functional dyspepsia, a significant difference of percentage of tongue coating was found. Percentage of tongue coating and weight of tongue coating showed significant correlation with total NDI-K score. Sterno-costal angle showed strong positive correlation with BMI and also showed significant difference between the non-overweight (BMI<23, n=32) and overweight ($BMI{\geq}23$, n=28) groups. Conclusions : Tongue coating thickness showed its potential as a new quantitative diagnostic indicator of functional dyspepsia. Further studies on the sterno-costal angle are anticipated to evaluate its potential as a new quantitative diagnostic indicator.

Comparative Study of Acute Dyspepsia, Functional Dyspepsia, Organic Dyspepsia by HRV(Heart Rate Variability) (심박변이도를 통한 급성, 기능성, 기질성 소화불량증의 비교연구)

  • Kim, Hyo-Jin;Kim, Bo-Kyung;Kim, Won-Il
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.2
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    • pp.75-85
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    • 2010
  • Objectives : This study was designed to evaluate the correlation between patterns of dyspepsia(acute dyspepsia, functional dyspepsia, dyspepsia with the organic disease) and autonomic nerve system dysfunction using HRV analysis. Methods : The patient group consisted of 88 patients diagnosed as a dyspepsia (Acute dyspepsia group-35 patients, Functional dyspepsia group-28 patients, Dyspepsia with the organic disease group-28 patients) who visited in the Oriental Medical Hospital of Dong-eui University from 2005.3.OO to 2008.8.OO. And the control group consisted of 33 patients diagnosed as a normal state of stomach during the same period. We checked HRV of the 4 groups over 5 minutes and compared the HRV index between groups. Results : 1. HF, LF, VLF and TP were significantly lower in the acute dyspepsia, functional dyspepsia and organic dyspepsia patient group than in the control group. 2. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. 3. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the functional dyspepsia patient group, but the differences were not statistically significant. 4. HF, LF, VLF and TP were lower in the functional dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. Conclusions : Compared to the control group, all of the dyspepsia patient groups showed the tendency that the overall activity of the autonomic nervous system and the activity of sympathetic nerves decreased. Although there was no significant difference in the suppression of the autonomic nervous system, chronic dyspepsia patient group was lower than acute dyspepsia patient group, functional dyspepsia patient group was lower than the organic dyspepsia patient group in HRV.

Surface Modification of Polymer Films by Vapor Phase Photografting of Functional Monomers (기상 UV 그라프트 반응에 의한 고분자 필름의 표면 개질)

  • Oh, Seung Hee;Oh, Se Heang;Lee, Jin Ho
    • Journal of Adhesion and Interface
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    • v.1 no.1
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    • pp.23-29
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    • 2000
  • Surface modification of hydrophobic polymeric materials to be hydrophilic or to have specific functional groups is of great importance for a diversity of applications of the materials. In this study, polyethylene (PE) film surfaces were modified by vapor phase photografting of hydrophilic vinyl monomers with different functional groups. The functional monomers were introduced on PE films by introducing the monomers in vapor phase using a vapor phase photografting apparatus designed by our laboratory. Functional monomers used were acrylic acid (negatively chargeable), acrylamide and allylalcohol (neutral), and allylamine and N,N-dimethyl aminopropyl acryamide (positively charged). The functional monomer-grafted PE film surfaces were characterized by the measurement of water contact angles and the attenuated total reflectance Fourier-transform infrared spectroscopy. The vapor phase photografting seems to be effective means for introduction of various functional groups onto polymeric substrates.

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Consumer Categorization Based on Perception of Functional Jacket and their Utilization of Functional Information and Hang-tag (기능성의류 인식에 따른 소비자 분류와 이에 따른 제품정보 및 행택 활용도 연구)

  • Bang, Giseong;Yoo, Shinjung
    • Science of Emotion and Sensibility
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    • v.18 no.4
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    • pp.75-86
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    • 2015
  • As a part of integrated study for technical communication between consumer and manufacturer of functional clothing, functional clothing consumers were categorized based on their perception of the functional outdoor jacket and the differences in the source of information and use of hang-tag were examined according to the groups. Questionnaire survey was conducted on 472 males and females in their 20s to 60s, who have experience of purchasing functional outdoor jackets. Perception of functional outdoor jackets was classified into four factors ('functionality', 'price', 'experience/knowledge' and 'brand/design') and the respondents were categorized into three groups according to the factors: 'unconversant/brand & design pursuing group', 'conversant/function pursuing group' and 'high-priced products preferring group'. 'Unconversant/brand & design pursuing group' was composed of high rate of office workers and students in their 20s and 30s who use internet most frequently as source of information while 'conversant/function pursuing group' was composed of high rate of professionals in their 40s and 50s who make the most frequent use of information on hang-tag. 'High-priced products preferring group', which has high rate of the elderly in their 60s and housewives, obtain their information mainly from salespersons. 'Unconversant/brand & design pursuing group' was satisfied with functional information more than other two groups and 'conversant/function pursuing group' concerned for the hang-tag and required more explanation of terminology used in hang-tag. The results effectively explained the features of consumer groups and their different responses toward the information of functional outdoor jacket.

The Effects of Trunk Stability Exercise on Functional Movement, Dynamic Balance Ability and Trunk Stability in Patients with Chronic Back Pain (체간 안정성 운동이 만성 요통 환자의 기능적 움직임과 동적 균형능력 및 체간 안정성에 미치는 영향)

  • Jung, Jooyeon;Kim, Taegyu;Kim, Sooyong
    • Journal of the Korea Convergence Society
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    • v.11 no.3
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    • pp.245-252
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    • 2020
  • The present study aimed to identify the effects of the trunk stability exercise on functional movement, dynamic balance, and trunk stability in patients with chronic low back pain, and to compare the difference among yoga exercise, pilates exercise and core exercise. Forty-three patients with chronic low back pain were divided into three groups; 15 yoga groups, 15 pilates groups, and 13 core exercise groups. All subjects were tested the Functional movement, dynamic balance, and trunk stability using Functional Movement Screen (FMS), Lower Quater Y-Balance Test (YBT-LQ) and Trunk Stability Test (TST), respectively, and after each 8-week exercise program was applied, all variables were retested. After exercising during 8 weeks, FMS, YBT-LQ and TST scores of all three groups were significantly improved, compared to before, but there were no interaction effect among three groups depending on application of exercise program. These results showed that yoga, pilates and core exercise help to improve functional movement, dynamic balance and trunk stability in adults with chronic low back pain.

The Effects of High Intensity Laser Therapy on Pain and Function of Patients with Frozen Shoulder

  • Jeon, Chun-Bae;Choi, Seok-Joo;Oh, Hyun-Ju;Jeong, Mu-Geun;Lee, Kwan-Sub
    • The Journal of Korean Physical Therapy
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    • v.29 no.4
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    • pp.207-210
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    • 2017
  • Purpose: This study was to identify the effectiveness of high-intensity laser therapy on pain and function of a frozen shoulder. Methods: Thirty patients were assigned to two groups: the experimental group (n=15) and the control group (n=15). Both groups received traditional therapy for 4 weeks, 3 days a week. The experimental group, however, received an additional high intensity laser therapy. Pain was measured using the visual analogue scale (VAS). The functional ability was measured using the patient specific functional scale (PSFS). A paired t-test was used to determine any differences before and after the treatment, and an independent t-test was used to determine any differences between treatment groups. Results: Both groups showed a statistically significant difference for VAS and PSFS score (p<0.05). In comparison between two groups, more experimental group than control group statistically significant difference (p<0.05). Conclusion: There seems to be a positive effect on pain and function of frozen shoulder from using high intensity laser therapy.

$CO_2$ Adsorption Behaviors of Activated Carbons Modified by Chelating Groups (킬레이트 관능기가 도입된 활성탄소의 이산화탄소 흡착거동)

  • Jang, Dong-Il;Park, Soo-Jin
    • Applied Chemistry for Engineering
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    • v.21 no.4
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    • pp.396-400
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    • 2010
  • In this work, the adsorption behaviors of activated carbons (ACs) containing chelating functional groups were studied in $CO_2$ removal. The ACs were modified by pyrolysis of peroxide and glycidyl methacrylate graft polymerization in order to induce chelating functional groups, such as diethylenetriamine groups on the AC surfaces. The surface functional groups of the ACs were characterized by scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). The textural properties of the ACs were analyzed by $N_2$/77 K isotherms. Adsorption behaviors of the ACs were observed in the amounts of $CO_2$ adsorption. From the results, we found that the chelating functional groups on the AC surfaces led to enhance selectivity and chemisorption on $CO_2$ adsorption in spite of decreasing the physical adsorption properties.

Comparing the Immediate Effectiveness of Lumbar Flexion and Extension Exercise With Regards to Pain, Range of Motion, Pelvic Tilt, and Functional Gait Ability in Patients With Lumbar Spinal Stenosis

  • Do, Hyun-ho;Chon, Seung-chul
    • Physical Therapy Korea
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    • v.26 no.4
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    • pp.10-19
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    • 2019
  • Background: In patients with lumbar spinal stenosis (LSS), lumbar flexion exercise (LFE) is considered a standard therapeutic exercise that widens the space between the spinal canal and intervertebral foramen. However, some researchers have reported that lumbar extension exercise (LEE) may improve lumbar pain and functional ability in patients with LSS. Although exercise intervention methods for patients with LSS have been widely applied in clinical settings, few studies have conducted comparative analysis of these exercise methods. Objects: This study aimed to compare the effects of LFE, LEE, and lumbar flexion combined with lumbar flexion-extension exercise (LFEE) on pain, range of motion (ROM), pelvic tilt angle, and functional gait ability in patients with LSS. Methods: A total of 30 patients with LSS, LFE (n1=10), LEE (n2=10), and LFEE (n3=10) were assigned to each of the three exercise groups. The numerical pain rating scale (NPRS), modified-modified schober test (MMST)-flexion, MMST-extension, pelvic tilt inclinometer, and 6-minute walking test (6MWT) were measured. Results: After the intervention, statistically significant differences were observed in the NPRS (p=.043), MMST-flexion (p<.001), MMST-extension (p<.001), and 6MWT (p=.005) between groups. According to the post hoc test, the NPRS was statistically significant difference between the LFEE and LEE groups (p=.034). The MMST-flexion was statistically significantly different between the LFE and LEE (p=.000), LFE and LFEE (p=.001), and LEE and LFEE (p=.001) groups. The MMST-extension was statistically significantly different between the LFE and LEE (p<.001), LFE and LFEE (p=.002), and LEE and LFEE (p=.008) groups. The 6MWT was statistically significantly different between the LFE and LFEE (p=.042) and the LEE and LFEE (p=.004) groups. Conclusion: This study suggested that LFEE was the most effective exercise for pain and functional gait ability in patients with LSS, LFE was the most effective exercise for lumbar flexion ROM, and LEE was the most effective exercise for lumbar extension ROM.

The Functional Role of the Corticospinal Track in Relation to Motor Functions in Chronic Stroke Patients (만성 뇌졸중 환자에서 피질 척수로와 운동 능력의 상관관계 연구)

  • Yeo, Sang-Seok
    • PNF and Movement
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    • v.12 no.3
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    • pp.143-150
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    • 2014
  • Purpose: The corticospinal tract (CST) is known to be an important pyramidal tract for walking and motor function. However, very little is known about the functional role of the CST in the recovery of motor function. In the current study, we investigated the relation between the CST and motor function in chronic hemiparetic stroke patients. Methods: Fifty-four patients and 20 normal subjects were recruited. The Functional Ambulation Category (FAC) was used in measurement of the walking ability. We classified patients into three groups according to the ability to walk independently: group A, patients who could not walk independently (FAC: 0-2); group B, patients who could walk independently (FAC: 3); and group C, patd walk functionally (stairs and uneven surfaces, FAC 4-5). The Motricity Index (MI) was used to measure the motor function of the affected upper and lower extremities (maximum score: 100). The fractional anisotropy (FA) value, apparent diffusion coefficient (ADC) value, and fiber volume of the CST were used for the diffusion tensor imaging (DTI) parameters. Results: In terms of the CST of the unaffected hemisphere, the FA value of group A was significantly lower than that of normal controls (p <0.05). The fiber volume of group C was significantly higher than that of normal controls (p <0.05). In contrast, the ADC values of all patient groups and the control group did not show any difference (p >0.05). In terms of lower MI and total MI, significant differences were observed between all patient groups (p <0.05). In addition, significant differences in terms of the upper MI scores were observed between groups A and C and between groups B and C (p <0.05); however, no significant difference was observed between groups A and B (p>0.05). Conclusion: The increased fiber volume of the CST in the unaffected hemisphere appears to be related to functional walking ability in chronic stroke patients. This result would be useful for elucidation of the neural recovery mechanism of walking and the investigation of new modalities for the recovery of walking following a stroke with CST injury.