• Title/Summary/Keyword: FPM

Search Result 65, Processing Time 0.039 seconds

Genome-wide association study for frozen-thawed sperm motility in stallions across various horse breeds

  • Nikitkina, Elena V.;Dementieva, Natalia V.;Shcherbakov, Yuri S.;Atroshchenko, Mikhail M.;Kudinov, Andrei A.;Samoylov, Oleg I.;Pozovnikova, Marina V.;Dysin, Artem P.;Krutikova, Anna A.;Musidray, Artem A.;Mitrofanova, Olga V.;Plemyashov, Kirill V.;Griffin, Darren K.;Romanov, Michael N.
    • Animal Bioscience
    • /
    • v.35 no.12
    • /
    • pp.1827-1838
    • /
    • 2022
  • Objective: The semen quality of stallions including sperm motility is an important target of selection as it has a high level of individual variability. However, effects of the molecular architecture of the genome on the mechanisms of sperm formation and their preservation after thawing have been poorly investigated. Here, we conducted a genome-wide association study (GWAS) for the sperm motility of cryopreserved semen in stallions of various breeds. Methods: Semen samples were collected from the stallions of 23 horse breeds. The following semen characteristics were examined: progressive motility (PM), progressive motility after freezing (FPM), and the difference between PM and FPM. The respective DNA samples from these stallions were genotyped using Axiom Equine Genotyping Array. Results: We performed a GWAS search for single nucleotide polymorphism (SNP) markers and potential genes related to motility properties of frozen-thawed semen in the stallions of various breeds. As a result of the GWAS analysis, two SNP markers, rs1141327473 and rs1149048772, were identified that were associated with preservation of the frozen-thawed stallion sperm motility, the relevant putative candidate genes being NME/NM23 family member 8 (NME8), olfactory receptor family 2 subfamily AP member 1 (OR2AP1), and olfactory receptor family 6 subfamily C member 4 (OR6C4). Potential implications of effects of these genes on sperm motility are herein discussed. Conclusion: The GWAS results enabled us to localize novel SNPs and candidate genes for sperm motility in stallions. Implications of the study for horse breeding and genetics are a better understanding of genomic regions and candidate genes underlying stallion sperm quality, and improvement in horse reproduction and breeding techniques. The identified markers and genes for sperm cryotolerance and the respective genomic regions are promising candidates for further studying the biological processes in the formation and function of the stallion reproductive system.

Preliminary Experimental Study for Water Recovery and Particulate Matter Reduction through a Hybrid System that Combines Exhaust Cooling and Absorption from Ships (선박배출 배기냉각과 흡수식이 결합된 하이브리드 시스템을 통한 물 회수 및 미세먼지 저감을 위한 기초실험연구)

  • Youngmin Kim;Donggil Shin;Younghyun Ryu
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.28 no.7
    • /
    • pp.1252-1258
    • /
    • 2022
  • The exhaust gas from the marine engines include a quantity of water vapor and particulate matter. The total particulate matter includes filterable particulate matter (FPM) and condensable particulate matter (CPM) that condense after releasing into the atmosphere. The portion of CPM is higher than that of FPM that is removable through the filter before discharging. An experimental setup for waste heat and water recovery and removal of CPM in the exhaust gas was tested using an industrial gas boiler in the laboratory. The water and CPM in the exhaust gas were removed through the first stage of cooling method and further removed through the second stage of absorption method. The efficiencies of water recovery were 73% after the first stage of cooling method and 90% after the second stage of absorption method. At the same time, the CPM was removed by 80-90% through the processes. The waste heat recovered could be used to process heat, and the water recovered could be used to process water in the ship. Furthermore, the CPM, which is a major source of the particulate matter but not subject to administrative regulation, could be removed effectively.

Organic Compounds in Condensable Particulate Matter Emitted from Coal Combustion (석탄 연소 시 배출되는 응축성 미세먼지의 유기 성분)

  • Jin Park;Sang-Sup Lee
    • Clean Technology
    • /
    • v.29 no.4
    • /
    • pp.279-287
    • /
    • 2023
  • Fine dust emitted from coal combustion is classified into filterable particulate matter (FPM) and condensable particulate matter (CPM). CPM is difficult to control with existing air pollution control devices, so research is being conducted to understand the characteristics of CPM. Components constituting condensable particulate matter (CPM) are divided into inorganic and organic components. There are many quantitative analysis results for the ionic components, which account for a significant proportion of the CPM inorganic components, but little is known about the organic components. Thus, there is a need for a quantitative analysis of CPM organic components. In this study, aromatic hydrocarbons (toluene, ethyl benzene, m,p-xylene, and o-xylene) and n-alkanes with 10 to 30 carbon atoms were quantitatively analyzed to understand the organic components of CPM emitted from a lab-scale coal combustor. Of the aromatic hydrocarbons, toluene accounted for 1.03% of the CPM organic components. On the other hand, the contents of ethyl benzene, m,p-xylene, and o-xylene showed low values of 0.11%, 0.18%, and 0.51% on average, respectively. Among the n-alkanes, triacontane (C30) showed a high content of 2.64% and decane (C10) showed a content of 2.05%. The next highest contents were shown with dodecane (C12), tetradecane (C14), and heptacosane (C27), all of which were higher than that of toluene. The n-alkane substances that had detectable concentrations showed higher contents than ethyl benzene, m,p-xylene, and o-xylene except for tetracosane (C24).

NUMERICAL STUDY ON TWO-DIMENSIONAL INCOMPRESSIBLE VISCOUS FLOW BASED ON GRIDLESS METHOD (2차원 비압축성 점성유동에 관한 무격자법 기반의 수치해석)

  • Jeong, S.M.;Park, J.C.;Heo, J.K.
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2009.04a
    • /
    • pp.239-244
    • /
    • 2009
  • The gridless (or meshfree) methods, such as MPS, SPH, FPM an so forth, are feasible and robust for the problems with moving boundary and/or complicated boundary shapes, because these methods do not need to generate a grid system. In this study, a gridless solver, which is based on the combination of moving least square interpolations on a cloud of points with point collocation for evaluating the derivatives of governing equations, is presented for two-dimensional unsteady incompressible Navier-Stokes problem in the low Reynolds number. A MAC-type algorithm was adopted and the Poission equation for the pressure was solved by successively in the moving least square sense. Some weighing functions were tested in order to investigate the up-winding effect for the convection term. Some typical problems were solved by the presented solver for the validation and the results obtained were compared with analytic solutions and the numerical results by conventional CFD methods, such as FVM.

  • PDF

Evolutionarily Optimized Design of Self-Organized Fuzzy Polynomial Neural Networks by Means of Dynamic Search Method of Genetic Algorithms (유전자 알고리즘의 동적 탐색 방법을 이용한 자기구성 퍼지 다항식 뉴럴 네트워크의 진화론적 최적화 설계)

  • Park Ho-Sung;Oh Sung-Kwun;Ahn Tae-Chon
    • Proceedings of the Korean Institute of Intelligent Systems Conference
    • /
    • 2005.11a
    • /
    • pp.475-478
    • /
    • 2005
  • 본 논문에서는 자기구성 퍼지다항식 뉴럴 네트워크(SOFPNN)를 구성하고 있는 퍼지 다항식뉴론(FPM)의 구조와 파라미터를 유전자 알고리즘을 이용하여 최적화시킨 새로운 개념의 진화론적 최적 고급 자기구성 퍼지 다항식 뉴릴 네트워크를 소개한다. 기존의 자기구성 퍼지 다항식 뉴럴 네트워크에서 모델을 설계할 때에는 설계자의 주관적인 특징과 시행착오에 의해서 모델을 구축하였다. 이러한 설계자의 경험을 배제하고 객관적이고 효율적인 모델을 구축하기 위해서 본 논문에서는 FPH의 파라미터들을 최적화 알고리즘인 유전자 알고리즘을 이용하여 동조하였다. 즉, 모델을 구축하는데 기본이 되는 FPN의 각각의 파라미터들-입력변수의 수, 다항식 차수, 입력변수, 멤버쉽 함수의 수, 그리고 멤버쉽 함수의 정점-을 동조함으로써 기존의 모델에 비해서 구조적으로 그리고 파라미터적으로 최적화된 네트워크를 생성할 수 있다. 뿐만 아니라 주어진 데이터의 특성을 모델 구축에 반영하고자 멤버쉽 함수의 정점 역시 유전자 알고리즘으로 동조하였다. 실험적 예제를 통하여 제안된 모델의 성능을 확인한 결과 기존의 퍼지모델 및 신경망 모델에 비해서 아주 우수한 근사화 능력과 일반화 능력을 가짐을 알 수 있다.

  • PDF

A Study on the Condensation Heat Transfer of Low Integral Fin Tubes (낮은 핀 관의 응축 열전달 성능에 관한 연구)

  • Han, Gyu-Il;Park, Seong-Guk
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.32 no.1
    • /
    • pp.67-77
    • /
    • 1996
  • The heat transfer performance of R - 11 vapor condensing on integral fin tubes has been studied using fin tubes having the fin density from 748 to 1654 fins per meter. Electric heater supplied heat energy to the boiler to generate R - 11 vapor over the range of 25-60W. Condensation rates of each tubes were tested under the condition of cooling water flow rate from 400l/h to 2500l/h. For the seven fin tubes tested, the best performance has been obtained with a tube having a fin density of 1417fpm and a fin height of 1.3mm. This tube has yielded a maximum value of the heat transfer coefficient of 16500W/$m_2$K, at a vapor to wall temperature difference of 3K. Experimental results of integral fin tubes have been compared with available predictive models such as Beatty - Katz's analysis, Webb's analysis, Sukhatme's analysis and Rudy's empirical relation. The experimental results were shown to be in good agreement with that of the Sukhatme's analysis.

  • PDF

Condensation Heat Transfer Coefficients of Flammable Refrigerants on Various Enhanced Tubes

  • Park Ki-Jung;Jung Dongsoo
    • Journal of Mechanical Science and Technology
    • /
    • v.19 no.10
    • /
    • pp.1957-1963
    • /
    • 2005
  • In this study, external condensation heat transfer coefficients (HTCs) of six flammable refrigerants of propylene (RI270), propane (R290), isobutane (R600a), butane (R600), dimethylether (RE170), and HFC32 were measured at the vapor temperature of $39^{\circ}C$ on a 1023 fpm low fin and Turbo-C tubes. All data were taken under the heat flux of $32\~116\;and\;42\~142kW/m^2$ for the low fin and Turbo-C tubes respectively. Flammable refrigerants' data obtained on enhanced tubes showed a typical trend that external condensation HTCs decrease with increasing wall subcooling. HFC32 and DME showed up to $30\%$ higher HTCs than those of HCFC22 due to their excellent thermophysical properties. Propylene, propane, isobutane, and butane showed similar or lower HTCs than those of HCFC22. Beatty and Katz' correlation predicted the HTCs of the flammable refrigerants obtained on a low fin tube within a mean deviation of $7.3\%$. Turbo-C tube showed the best performance due to its 3 dimensional surface geometry for fast removal of condensate.

A Study on Finned Tube Used in Turbo Refrigerator(II) - on boiling heat transfer - (터보 냉동기용 핀 튜브에 관한 연구(II) - 비등 열전달에 관하여 -)

  • Han, Kyu-Il;Kim, Si-Young;Cho, Dong-Hyun
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.5 no.2
    • /
    • pp.119-127
    • /
    • 1993
  • This work studies for heat transfer and pressure drop performance of integral inner and outer fin tubes, designed to enhance the heat transfer performance of smooth tubes for in recipro and turbo refrigerator or high performance compact heat exchangers. Eight different inner spiral fin copper tubes with integral fin at outside surfaces were employed to improve boiling heat transfer coeffcient. For comparison, tests were made using a plain tube having the inside diameter and an outside diameter equal to that at the root of the fins for the finned tubes. Pool boiling heat transfer is investigated experimentally and theoretically on single tube arrangement. The refrigerant evaporates at a saturation state of 1 bar on the outside tube surface heated by hot water. The refrigerant R11 ($CFCl_3$) was used at a pressure of $P_s=1bar$ as a convenient test fluid with a boiling temperature of $T_s=23.6^{\circ}C$. The observed heat transfer enhancement of boiling for finned tubes significantly exceeded that to be expected on grounds of increased area. The maximum Vapor - side enhancement(i.e., vapor - side heat transfer coefficient of finned tube/vapor - side coefficient for plain tube) was found to be around 4 at 1299fpm - 30grooves tube.

  • PDF

Study on Airborne Particulate Matter ($PM_{10}$) Monitoring in Urban and Rural Area by Using Gent SFU Sampler and Instrumental Neutron Activation Analysis (중성자 방사화분석법과 Gent SFU 샘플러를 이용한 도시의 농촌지역의 대기분지($PM_{10}$)관측 연구)

  • 정용삼;문종화;김선하;박광원;강상훈
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.16 no.5
    • /
    • pp.453-467
    • /
    • 2000
  • The aim of this research is to collect and characterize fine particles (FPM:$\leq$2.5${\mu}{\textrm}{m}$) and coarse particles (CPM: 2.5~10${\mu}{\textrm}{m}$) using a low volume air sampler provided by the IAEA, at urban (Taejon) and rural area(Wonju) for a period of about two years(April 1996 to May 1998) and to promote a use of nuclear analytical techniques for air pollution studies. For the collection of airborne particulate matter (PM(sub)10), the Gent stacked filter unit sampler and polycarbonate membrane filters were employed. The concentration of trace elements in collected APM samples were determined byu instrumental Neutron Activation Analysis. For validation of the analytical data, internal quality control were implemented by using both the comparison of the analytical results of standard reference materials(NIST SRM 1648) and interlaboratory comparison for proficiency test (NAT-3). The standard uncertainty was less than 15% and Z-score of two samples were within $\pm$1. The monitoring of (PM(sub)10) mass concentration and elemental concentrations were carried out weekly. The average mass concentration of (PM(sub)10) in urban and rural areas were 59.2$\pm$36.5$\mu\textrm{g}$/㎥ and 41.4$\pm$23.7$\mu\textrm{g}$/㎥, respectively. To investigate the emission source, the enrichment factors were calculated for the fine and coarse particle fractions at two sites, respectively and these values were classified for anthropogenic and soil origin elements.

  • PDF

The Effect of Gender on the Gastric Alcohol Dehydrogenase (GADH) Activity in Normal Sprague-Dawley Rats (Sprague-Dawley계 정상 흰쥐에서 위점막 알코올 탈수소효소 활성에 대한 성별의 영향)

  • 성기철;강주섭;이창호;고현철;신인철;강석한;전용철;엄애선
    • Biomolecules & Therapeutics
    • /
    • v.8 no.1
    • /
    • pp.38-43
    • /
    • 2000
  • Several studies have shown that the stomach has sufficient alcohol dehydrogenase (ADH) activity to metabolize some amount of orally administered alcohol and the sex-related differences in the first-pass metabolism of alcohol might be associated with differences in the activity of gastric ADH(GADH). The aim of this study was to asses the sex-related differences in GADH in 48 male and 48 female Sprague-Dawley rats aged 1, 4, 10, 15, 20, and 30 weeks which each aged group had same sex ratio. The GADH activity was determined spectrophotometrically at 37$^{\circ}C$. The formation of NADH was monitored at 340nm for 10 minutes in the 1 ml of reaction mixture (0.5 M of Tris-HCl, pH 7.2 + 1.5 M of ethanol + 2.8 mM of NAD + 30 $\mu$l gastric mucosal supernatant). The GADH activity (nM of NADH/min/mg of cytosolic protein) was calculated using molecular extinction coefficient of 6.22 $\textrm{cm}^2$/$\mu$M for NADH. The GADH activities were 2.94$\pm$0.82 (n=48) in female rats and 3.34$\pm$2.17 (n=48) in male rats and had not significant difference between sex. However, the GADH activities were significantly (p<0.01) higher in female (1.91$\pm$0.59 and 3.30$\pm$0.49) than in male (0.68$\pm$0.43 and 1.92$\pm$0.81) of 1 and 4 weeks rats. However, it was significantly (p<0.05) higher in male (6.48$\pm$1.81, 3.65$\pm$1.04 and 5.13$\pm$1.30) than in female (4.23$\pm$1.23, 2.18$\pm$0.77 and 2.56$\pm$0.93) of 10, 20 and 30 weeks rats, respectively. Therefore, the results suggested that sex-related differences of the GADH activities in same aged rats were existed by age.

  • PDF