• Journal of Microbiology and Biotechnology
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• 제33권5호
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• pp.680-686
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• 2023

Aging is a complex series of multi-organ processes that occur in various organisms. As such, an in vivo study using an animal model of aging is necessary to define its exact mechanisms and identify anti-aging substances. Using Drosophila as an in vivo model system, we identified Crataegus pinnatifida extract (CPE) as a novel anti-aging substance. Regardless of sex, Drosophila treated with CPE showed a significantly increased lifespan compared to those without CPE. In this study, we also evaluated the involvement of CPE in aging-related biochemical pathways, including TOR, stem cell generation, and antioxidative effects, and found that the representative genes of each pathway were induced by CPE administration. CPE administration did not result in significant differences in fecundity, locomotion, feeding amount, or TAG level. These conclusions suggest that CPE is a good candidate as an anti-aging food substance capable of promoting a healthy lifespan.

• Safe Food
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• 제3권3호
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• pp.19-22
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• 2008

• 한국어업기술학회:학술대회논문집
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• 한국어업기술학회 2001년도 추계 수산관련학회 공동학술대회발표요지집
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• pp.22-22
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• 2001

Enzymes have been used in practical applications as diverse as brewing and industrial fermentations, detergent, analytical determinations and recombinant DAN technology. As processing aids, enzymes have been used in the manufacture of food products to improve their quality, solubility and stability for centuries. About 50％ of the enzyme used as industrial processing aids are pretenses which have been used in a number of industrial applications including laundry detergents, chill proofing, meat tenderizing, fermented sauces, and the production of pharmaceuticals. (omitted)

• Toxicological Research
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• 제19권1호
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• pp.1-12
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• 2003

New breeding method by genetic engineering is expected as a key technology to solve food shortage due to the growing world population in the year 2000s. Many genetically modified organisms (GMOs) were already developed and the commercial cultivation had started. The first GMO, Flavr Savr tomato, which rotted at a much slower pace than ordinary ones, was developed in US in 1994. Since then, over than 70 different agricultural products including corn, cotton, soybean, papaya, potato, and squash made with genetically modified plants are reportedly on sale worldwide. Supporters favor the GMOs because they have greater yields, longer shelf lives and stronger resistance to disease and insects. On the other hand, opponents say that the supporters ignore a potential danger that they may damage the environment as well as human beings. To assure the safe development and use of GMOs as food and other biotech products, the possible risks on biological environment and human health should be throughly examined and regulated by developer and government. Because the biosafety problem is a global, environmental, and trade issue, a new international treaty is under development. The Cartagena Protocol on Biosafety was adopted at the 1 st Extraordinary Conference of Parties of the Convention on Biological Diversity which was held at Mont-real, Canada, Jan. 29th, 2000. The adoption of the Protocol is seen as a breakthrough in that it is based on the" Precautionary Principle" despite scientific uncertainties surrounding potential risks that GMOs may inflict on human health and the environment and that it has laid the ground for introduction of specific steps to handle international trading of GMOs. In this paper, the authors would like to introduce the current status and perspective of environmental and human risk assessment of GMOs.t of GMOs.

• Journal of Microbiology
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• 제33권2호
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• pp.95-102
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• 1995

A probability identification matrix of acidophilic Streptomyces was constructed. The phenetic data of the strains were derived from numerical classification described by Seong et al. The minimum number of diagnostic characters was determined using computer programs for calculation of different separation indices. The resulting matrix consisted of 25 clusters versus 53 characters. Theoretical evaluation of this matrix was achieved by estimating the chuster overlap and the identification scores for the Hypothetical Median Organisms (HMO) and for the representatives of each cluster. Cluster overlap was found to be relatively small. Identification scores for the HMO and the randomly selected representatives of each cluster were satisfactory. The matrix was assessed practically by applying the matrix to the identification of unknown isolates. Of the unknown isolates, 71.9% were clearly identified to one of eight clusters. The numerical classification data was also used to design a selective isolation medium for antibiotic-producing organisms. Four chemical substances including 2 antibiotics were determined by the DLACHAR program as diagnostic for the isolation of target organisms which have antimicrobial activity against Micrococcus luteus. It was possible to detect the increased rate of selective isolation on the synthesized medium. Theresults show that the numerical phenetic data can be applied to a variety of purposes, such as construction of identification matrix and selective isolation medium for acidophilic antinomycetes.

• 한국식품영양과학회지
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• 제36권4호
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• pp.470-475
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• 2007

두부에서 분리한 부패 미생물 16균주와 6종류의 병원성 미생물에 대한 황금 에탄을 추출물의 항균활성을 조사한 결과 분리 13균주와 병원성 미생물에 대해서 항균활성을 나타내었으며, 두부 부패 미생물인 KN-4, KN-6, KN-10, KN-20에 대하여 황금 에탄을 추출물 0.05% 이상의 농도에서 성장억제 현상을 나타내었다 선발균주를 동정한 결과, KN-4, KN-6, KN-10과 KN-20 공히 Bacillus sp.로 동정되었다. 황금 에탄을 추출물은 Listeria monocytogenes ATCC 19115, Pseudomonas fluorescens ATCC 21541, Staphylococcus aureus ATCC 29273, Salmonella Typhimurium ATCC 21541, Vibrio parahaemolyticus ATCC 17802, Aeromonas hydrophila KCTC 2358에 대해 항균활성을 나타내었으며, 0.5% 이상 농도에서 성장이 억제되었다 황금에탄올 추출물은 $80^{\circ}C$에서 30min, $100^{\circ}C$에서 30 min, $121^{\circ}C$에서 15 min 열처리에 의해, 공시균주에 대한 항균활성이 다소 감소하는 현상을 나타내었으나 열처리 후에도 두부 부패미생물과 공시 병원성 미생물에 대한 항균활성은 뚜렷하게 유지되었다. 두부 부패 미생물과 병원성 미생물에 대한 황금 에탄을 추출물의 최소저해농도는 각각 0.1%와 0.5%이었다.

• Journal of Plant Biotechnology
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• 제36권4호
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• pp.301-308
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• 2009

Higher agricultural commodity prices are a particular concern for food importing countries like Korea that has a very low self-sufficiency ratio. Korean people eat approximately 4.5 million metric tons of rice each year, which is met without a problem by domestic production. The domestic production of corn and soybean which are important raw materials for commercial food processing and livestock feed is only minimal. Demands of corn and soybean in Korea are approximately 7.2 million and 1.3 million metric tons per year, respectively. Since Korean consumers are reluctant to accept biotech (GM) foods, Korean food processors are fighting an up-hill battle in purchasing non-biotech (non- GM) crops which are becoming scarce.

• 한국어류학회지
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• 제9권2호
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• pp.221-227
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• 1997

1994년 1월부터 1994년 12월까지 광양만 대도주변 잘피밭에서 채집된 주둥치의 식성을 조사하였다. 주둥치는 주로 요각류와 게의 유생을 먹었으며, 그 외 갯지렁이류, 단각류, 곤쟁이류, 새우류 등을 소량씩 먹었다 주둥치가 성장함에 따라 먹이생물의 조성 및 크기가 점차 변하였다. 체장이 작은 크기에서는 요각류를 상당히 많이 먹었으나, 체장이 증가하면서 위내용물 중 요각류가 차지하는 비율이 점차 낮아진 반면, 갯지렁이류의 비율은 점차 증가하였다. 한편, 게의 유생은 전 크기군에 걸쳐 지속적으로 많이 섭이되었다. 대체적으로 계절에 관계없이 게 유생의 섭이 비율은 거의 일정하였으나, 요각류와 갯지렁이류의 비율은 뚜렷한 계절 변동을 보였는데, 이는 출현하는 주둥치의 크기 조성이 계절에 따라 달라졌기 때문이다.

• Food Science and Biotechnology
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• 제18권4호
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• pp.872-877
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• 2009

By-products of marine organisms including salmon, skate, flatfish, and yellow goosefish were investigated to search for new source of chondroitin sulfate (CS). Agarose gel electrophoresis with chondroitinase depolymerization showed that purified chondroitin sulfate did not contain any other glycosaminoglycans. 1H-nuclear magnetic resonance (NMR) spectra were acquired to confirm the structure and purity. The average molecular weight ranging from 22 to 64 kDa was determined by high performance size exclusion chromatography. Disaccharide compositions and purities were determined by strong anion exchange-high performance liquid chromatography (SAX-HPLC) after chondroitinase ABC depolymerization. SAX-HPLC data exhibited that the purity was from $81.7{\pm}1.3$ to $114.2{\pm}2.5%$ and the yield was from 1.3 to 12.5%. All analytical results indicate that salmon cartilage, skate cartilage, and yellow goosefish bone could be promising sources of CS to substitute shark cartilage CS in commercial neutraceuticals.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2006년도 전기학술대회논문집
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• pp.273-274
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• 2006

The sea is origin of all lift, and 90% of the all living organisms are in the sea. The biosynthesis is very different. Many organisms are kept on a lower or developed to another evolutionary level than on shore. Our society is increasing demand and need for marine food and this food has to product at onshore or offshore fish farming sites. Ocean fish farms have a special operation properties such as a good quality water, net cage, sheltered locations and feeding system. The farming site is controlled and monitored for fish welfare as ammonia($NH_3$), temperature, the speed of a running fluid. Specially, the fish farm is seriously influenced by ammonia. In this paper, $NH_3$ monitoring system for ocean fish farm is researched for the suitable fish farming sites, and test equipment is designed for achieving practical data. The equipment wit monitoring algorithm is expected to the useful system for ocean fish farm.