• Applied Chemistry for Engineering
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• v.10 no.4
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• pp.599-602
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• 1999

Chitosan was depolymerized by using nitrous acid. In order to synthesize new fluorinated chitosan oligomer(FCO) derivative, free amine groups of resulting low molucular weight chitosan oligomers were reacted with trifluoroacetic anhydride. The structure changes in the samples were conformed by using FT-IR, $^{1}H\;NMR$, $^{13}C\;NMR$ and $^{19}F\{^{1}H\}NMR$. Antiviral activity of FCO was studied by measuring DAN amounts of the replication viruses at 36 hr after the cells were infected with the viral solution containing FCO of various concentrations. The viral replications in the cells infected with the viral solution containing FCO were proportionally decreased with the FCO does, compared to those of the control groups, indicating that FCO efficiently inhibits viral infection. In particular, viral replication was decreased to 40% in the 1% FCO-treated cells.

• Bulletin of the Korean Chemical Society
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• v.11 no.6
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• pp.511-515
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• 1990

Ab initio calculations with MP3 and CISD method were performed for the FCO and $FCO^+$. The equilibrium geometry of FCO shows the reasonable agreement with experimental values. $FCO^+$ has a linear geometry with $R_{CF}=1.213\;and\;R_{CO}=1.118{\AA}$. The quadratic force constants of $FCO^+$ are 23.21 md ${\AA}^{-1}$ for CO stretch and 12.38 md ${\AA}^{-1}$ for CF stretch. The cubic force constants and the other molecular constants are also calculated.

• Journal of Veterinary Science
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• v.23 no.2
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• pp.27.1-27.16
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• 2022

Background: The role of Toll-like receptors (TLRs) in a feline infectious peritonitis virus (FIPV) infection is not completely understood. Objectives: This study examined the expression of TLR3, TLR7, TLR9, tumor necrosis factor-alpha (TNF-α), interferon (IFN)-β, and interleukin (IL)-10 upon an FIPV infection in Crandell-Reese feline kidney (CRFK) cells and feline monocytes. Methods: CRFK cells and monocytes from feline coronavirus (FCoV)-seronegative cats and FCoV-seropositive cats were infected with type II FIPV-79-1146. At four, 12, and 24 hours post-infection (hpi), the expression of TLR3, TLR7, TLR9, TNF-α, IFN-β, and IL-10, and the viral load were measured using reverse transcription quantitative polymerase chain reaction. Viral protein production was confirmed using immunofluorescence. Results: FIPV-infected CRFK showed the upregulation of TLR9, TNF-α, and IFN-β expression between 4 and 24 hpi. Uninfected monocytes from FCoV-seropositive cats showed lower TLR3 and TLR9 expression but higher TLR7 expression compared to uninfected monocytes from FCoV-seronegative cats. FIPV-infected monocytes from FCoV-seropositive cats downregulated TLR7 and TNF-α expression between 4 and 24 hpi, and 4 and 12 hpi, respectively. IFN-β was upregulated early in FIPV-infected monocytes from FCoV-seropositive cats, with a significant difference observed at 12 hpi compared to FCoV-seronegative cats. The viral load in the CRFK and FIPV-infected monocytes in both cohorts of cats was similar over time.ConclusionTLR7 may be the key TLR involved in evading the innate response against inhibiting TNF-α production. Distinct TLR expression profiles between FCoV-seronegative and FCoV-seropositive cats were observed. The associated TLR that plays a role in the induction of IFN-β needs to be explored further.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2005.11a
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• pp.307-310
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• 2005

This Study was performed for the Insensitive Munition Technology Program contract between Roxel and ADD. Two Slow Coo-off(SCO) tests and One fast Cook-off(FCO) test have been made based on MIL-STD-2105C. SCO and FCO tests were made in order to evaluate the behaviour of the hybrid rocker motor with insensitive igniter and two types of propellants of which burning rates were 9.8 mm/s and 21.2 mm/s @ 7 MPa each other. The Reaction level of the two rocker motors to SCO test was classified as type IV and that of FCO test was classified as type V.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.65.2-65.2
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• 2013

We present a study of outflows on 24 embedded young stellar objects (YSOs), which are selected from the sources of the Dust, Ice, and Gas in Time (DIGIT) Herschel key program. Molecular outflow activity, which is believed to have strong dependence on accretion process, is the most powerful in the early embedded phase of star formation and declines as the central protostars evolve to the main sequence stage. In order to study the relation between the CO outflow observed in low J transitions and the properties of protostars, we mapped the CO outows of the selected targets in J = 1-0 and J = 2-1 lines with the 14-m TRAO telescope and the 6-m SRAO telescope, respectively. We estimate CO outflow momentum fluxes (Fco) and compare with bolometric luminosity, Lbol, bolometric temperature, Tbol, and the FIR molecular line luminosities of CO, $H_2O$, OH and [O I], which were detected by the Herschel-PACS observations. We found that $Fco_{1-0}$ is greater than $Fco_{2-1}$, and the mean ratio is about 2. L1455-IRS3 and IRAM04191 have high Fco in spite of low $L_{bol}$. The well known correlation between Fco and $L_{bol}$. is not very evident from all our samples. However, Fco and $L_{bol}$. show a rather strong correlation if L1455-IRS3 and IRAM04191 are excluded. Fco shows little correlation with FIR line luminosities of individual species, while the total FIR line luminosity summed over CO, $H_2O$, OH, and [OI] lines seems to have some correlation. In addition, we report 22 GHz $H_2O$, and 44 GHz CH3OH maser line detections in four sources out of the 24 YSOs.

• The KIPS Transactions:PartA
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• v.17A no.4
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• pp.197-202
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• 2010

The recorder at observatory can save the measured data from water gauge and rain gauge at an interval of five minutes. And then, the RTU (Remote Terminal Unit) in observatory sends the measured data in the recorder to the TM (Telemetering) in FCO (Flood Control Office) at an interval of ten minutes using VHF or satellite communication. But the transmitted data is not the stored data at the recorder, it is just data that is measured at an interval of ten minutes. In the FCO, the transmitted data is analyzed in order to forecast the flood. And also one of the most important things is the maintenance of an observatory. In this paper, an effective management system for the flood forecast is proposed. It uses the CDMA and the Blutooth technology on PDA. The proposed system is very portable, and also easily able to send the data stored at the recorder in observatory to TM in FCO without RTU. And it allows us to view remotely the data of other observatories by downloading from the FCO. Hence the system can do efficiently the maintenance of observatory without wasting manpower and time.

• Journal of the Korean Home Economics Association
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• v.34 no.3
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• pp.89-105
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• 1996

The purpose of the study was to investigate the causal relationships between communication situation - communication apprehension(CA), family communication orientation(FCO), individual viewing motives and perceived realism of aggressive films - and aggression. The data from 193 high school students were analysed by SAS program. The respondents were asked to complete the self-report questionnaires, and the data were analysed by Cronbach's to the reliability, factor analysis, frequencies, percentage, means, standard deviation, Pearson's correlation coefficient, Duncan's multiple test, multiple regression, and path analysis, The results showed that CA was positively related to both aggression against the materials, and potential aggression. FCO had no direct effect on aggression but concept-oriented family affected indirect effect on aggression through viewing motives. The ritualistic motives were more positively related to aggression and identity than instrumental motive.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.265-272
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• 2010

Follicular cystic ovary (FCO) is one of the most frequently diagnosed ovarian diseases and is a major cause of reproductive failure in mammalian species. However, the mechanism by which FCO is induced remains unclear. Genetic alterations which affect the functioning of many kinds of cells and/or tissues could be present in cystic ovaries. In this study, we performed a comparison analysis of gene expression in order to identify new molecules useful in discrimination of bovine FCO with follicular cystic follicles (FCFs). Normal follicles and FCFs were classified based on their sizes (5 to 10 mm and $\geq25mm$). These follicles had granulosa cell layer and theca interna and the hormone $17{\beta}$-estradiol ($E_2$)/ progesterone ($P_4$) ratio in follicles was greater than one. Perifollicular regions including follicles were used for the preparation of RNA or protein. Differentially expressed genes (DEG) that showed greater than a 2-fold change in expression were screened by the annealing control primer (ACP)-based PCR method using $GeneFishing^{TM}$ DEG kits in bovine normal follicles and FCFs. We identified two DEGs in the FCFs: ribosomal protein L15 (RPL15) and microtubule-associated protein 1B (MAP1B) based on BLAST searches of the NCBI GenBank. Consistent with the ACP analysis, semi-quantitative PCR data and Western blot analyses revealed an up-regulation of RPL15 and a down-regulation of MAP1B in FCFs. These results suggest that RPL15 and MAP1B may be involved in the regulation of pathological processes in bovine FCOs and may help to establish a bovine gene data-base for the discrimination of FCOs from normal ovaries.

• Korean Journal of Veterinary Service
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• v.45 no.2
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• pp.101-110
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• 2022

This study was performed to investigate infectious gastrointestinal diseases in 115 Korean cats (83 indoors and 32 outdoors) with digestive signs such as diarrhea, anorexia or abdominal distention. Detection of infectious pathogens was analyzed using real-time PCR. As a result, 85 of 115 Korean cats were detected with feline corona virus (FCoV), feline parvo virus, Group A rotavirus, Clostridium perfringens (C. perfringens), Campylobacter coli (C. coli), Campylobacter jejuni, enterotoxigenic Escherichia coli, enteropathogenic Escherichia coli, Salmonella spp., Tritrichomonas foetus, Cyclospora cayetanensis, and Giardia lamblia. The most frequently detected pathogen was C. perfringens (52 cats, 61.2%), followed by FCoV (43 cats, 50.6%) and C. coli (16 cats, 18.8%). Also, single infection was the most common (43 cats), followed by double infection in 31 cats, triple infection in 7 cats, and quadruple infection in 4 cats. There was no significant relationship between pathogen detection and age, gender, living environment, weather, and diarrhea. However, there was a significant difference between the age group under 1 year and the age group 1~7 (P value<0.05). In this study, cats with suspected gastrointestinal infection were randomly evaluated, and other factors that could affect pathogen detection were insufficiently considered. For this reason, additional epidemiological investigations with a larger number of cats and sufficient consideration of the causes that may affect the results are needed. Nevertheless, it is thought that this study can also provide valuable information on gastrointestinal pathogens in Korean cats.

• Korean Journal of Veterinary Service
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• v.40 no.2
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• pp.143-147
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• 2017

A Korean domestic short hair (1-year-old, male) presented with 2 to 3 weeks of seizures, aggressive behavior, vomiting, anorexia, and lethargy. The frequency of seizure had gradually increased from once a week to once every 3 hours. Physical and neurologic examination, diagnostic screening tests, including complete blood count (CBC), serum chemistry, electrolyte, coagulation test, X-ray, ultrasonography, and urinalysis were performed. Feline Leukemia Virus (FeLV), Feline Immunodeficiency Virus (FIV) and Toxoplasma spp. All tested negative, but the Feline Corona Virus (FCoV) kit revealed a positive result. To determine the exact diagnosis, magnetic resonance imaging (MRI) was performed but yielded no specific findings. The patient was then diagnosed with idiopathic epilepsy and treatment of phenobarbital was initiated. A month's treatment with phenobarbital proved ineffective as symptoms worsened. Zonisamide was then selected as an additional anticonvulsant. After adding zonisamide, symptoms improved, and seizures abated for 15 months. This is the first case report in South Korea describing the use of phenobarbital and zonisamide in the treatment of a cat with idiopathic epilepsy.