• Title/Summary/Keyword: FAS

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A Detection Method for Synchronization Secession in Frame for The EUROCOM Communication System (EUROCOM 통신시스템의 동기이탈 검출 방법)

  • 이승수
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.10A
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    • pp.853-858
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    • 2003
  • In the EUROCOM communication system, it defines frame structures as data rate. each frame includes a synchronization bit as frame alignment signal. In my paper proposes a FAS detector for determining state of synchronization as compare received data with FAS pattern, also presents a new detection method for synchronization secession which can decide acquisition state of synchronization with searching a synchronization channel through entire channels in frame.

Inhibition of tyrosine phosphatases blocks plasma membrane blebbing during Fas- induced apoptosis of Jurkat T cells without affecting the cytotoxicity of Fas-ligation

  • Cho, Jun-Young;Kim, Kwang-Dong;Kho, Chang-Won;Park, Sung-Goo;Chung, Kyeong-Soo;Lim, Jong-Seok
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.135.2-135.2
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    • 2003
  • Plasma membrane blebs are observed in many types of apoptotic cells, but their processes of formation remain to be clarified. In the present study, we investigated whether there is a relationship between change of intracellular phosphotyrosine levels and biochemical apoptotic events in Jurkat T cells undergoing apoptosis by agonistic anti-Fas antibody. When Jurkat cells were treated with Fas-antibody in the presence or absence of pretreatment with sodium orthovanadate ($Na_3${VO}_4$), a phosphotyrosine phosphatase (PTPase) inhibitor, membrane blebs disappeared in orthovanadate-treated cells. (omitted)

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Effects of Benzalkonium Chloride on the growth and survival of Human corneal epithelial cells (점안액 보존제 성분 Benzalkonium Chloride에 의해 유도된 각막상피세포의 세포고사 유도)

  • Kim, Jai-Min;Lee, Seok-Ju;Seo, Eun-Sun
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.189-195
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    • 2002
  • The aim of this study was to investigate the action of benzalkonium chloride (BAC) used as a preservative in most ophthalmic topical solutions, on human corneal epithelial (HCE) cells in vitro. HCE cell line was exposed to BAC solutions at various concentrations (0.01%~0.0001%) for 15 minutes followed by 24 hours of cell recovery. Cell viability was assessed using MTT assay and chromatin condensation with a Hoechst 33342 test. The expression of membrane protein Fas and Fas ligand was examined by western blot and immunocytochemistry, and DNA fragmentation was studied by agarose gel electrophoresis. A significant decrease of membrane integrity with chromatin condensation was observed with BAC tested at concentrations of 0.005% and higher. BAC was cytotoxic preservatives in this study. An apoptotic mechanism appeared to be present at low concentrations of BAC, whereas a necrotic process appeared at higher concentrations. A functional Fas-mediated apoptotic pathway is present in cultured HCE cells and can be activated by upregulation of Fas expression with BAC.

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Effects of Compounds from Physalis angulata on Fatty Acid Synthesis and Glucose Metabolism in HepG2 Cells via the AMP-activated Protein Kinase Pathway

  • Hoa, Hoang Thai;Thu, Nguyen Thi;Dong, Nguyen Thuong;Oanh, Tran Thi;Hien, Tran Thi;Ha, Do Thi
    • Natural Product Sciences
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    • v.26 no.3
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    • pp.200-206
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    • 2020
  • The ability of the total extract from Physalis angulata; three fractions after partitioning with n-hexane, ethyl acetate (TBE), and water; and four withanolides (compounds 1 - 4) to phosphorylate 5'-adenosine monophosphate-activated protein kinase (AMPK) and acetyl-CoA carboxylase (ACC) in HepG2 cells was evaluated. The TBE fraction (50 ㎍/mL) activated p-ACC and p-AMPK expression most strongly. Compounds 1 - 4 (10 μM) upregulated p-ACC expression at different levels. Compound 4 induced the most significant changes in p-AMPK expression, followed by 1 and 2. Sterol regulatory element-binding proteins (SREBPs) play a functional role in the transcriptional regulation of the lipogenic pathway, including fatty acid synthase (FAS) and ACC. The effects of compounds 2 and 4 (10 μM) on FAS and SREBP-1c expression under high glucose conditions (30 mM) in HepG2 cells were evaluated further. Both dose-dependently inhibited FAS and SREBP-1c expression as well as lipid accumulation (1 - 10 μM) were compared to high-concentration glucose control, which upregulated FAS and SREBP-1c. These results suggest that compounds 2 and 4 upregulate AMPK, suppress FAS and SREBP-1c, and have potential effects on glucose and lipid metabolism.

Effects of Dietary Energy Density on Growth, Carcass Quality and mRNA Expression of Fatty Acid Synthase and Hormone-sensitive Lipase in Finishing Pigs

  • Liu, Z.H.;Yang, F.Y.;Kong, L.J.;Lai, C.H.;Piao, X.S.;Gu, Y.H.;Ou, X.Q.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.10
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    • pp.1587-1593
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    • 2007
  • A single factorial experiment was conducted to test the effects of three dietary levels of energy on mRNA expression of fatty acid synthase (FAS-mRNA) and hormone-sensitive lipase (HSL-mRNA) and their association with intramuscular fat in finishing pigs. 72 crossbred (Large $White{\times}Rongchang$) barrows with an average initial body weight of 20.71 (s.e. 0.1) kg, were randomly allotted to three dietary treatments (11.75, 13.05 and 14.36 MJ DE/kg) and fed until slaughtered at 100 or 101 kg. The diets were iso-nitrogenous and iso-essential amino acids. The growth performances including the duration of finishing were changed linearly (p<0.05) or quadratically (p<0.05) with increased dietary energy levels. The effects of dietary energy content on the percentage of external fat, intramuscular backfat and the fat thickness were linear (p<0.05). The content of dietary energy increased FAS-mRNA linearly or quadratically, while HSL-mRNA decreased linearly or quadratically in backfat and Longissmus dorsi muscle. Meanwhile, significant positive correlations (p<0.05) were found between energy level and intramuscular fat, FAS-mRNA or the ratio of FAS-mRNA to HSL-mRNA, between the ratio of FAS-mRNA to HSL-mRNA and intramuscular fat. However, the correlations between HSL mRNA and dietary energy or intramuscular fat were negative (p<0.05). The results indicated that dietary energy level regulates lipid accumulation, especially intramuscular fat, possibly by modulating the mRNA of FAS and HSL together rather than individually.

Fluidity of Cement Paste and Fluidity and Compressive Strength of Cement Mortar Substituted by Pozzolanic fine Powders and II-Anhydrite (포졸란계 미분말과 ∥ 형 무수석고 치환 시멘트 페이스트 유동성과 시멘트 모르타르의 유동성 및 압축강도)

  • 노재성;이범재;김도수;이병기
    • Magazine of the Korea Concrete Institute
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    • v.9 no.3
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    • pp.149-156
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    • 1997
  • In order to improve compressive strength of cement mortar, powder admixture(FAS) was mmufactured by mixing fly ash. Il-anhydite and silica hume, and superplasticizer was used for the control of fluidity reduction with the use of this admixture. Cement was substituted by 10, 20wt% of FAS respectively. At W/S = 0.40, the fluidity of' cement paste substituted by PAS was decreased. NSF and NT-2 were very effective fbr the control of fluidity reduction. As the particle size of U -anhydrite was fine, the fluidity of cement mortar was increased. The fluidity reduction of cement mortar substituted by 10wt% of FAS was controlled. The compressive strength of cement mortar substituted by 10wt% of FAS showed higher. value than that of 20wt%, expecially specimen(C1) substituted by 10wt% of $\gamma$ had the highest compressive strength value.

Identification of Single Nucleotide Polymorphism Marker and Association Analysis of Marbling Score in Fas Gene of Hanwoo

  • Kim, Seung-Chang;Lee, Seung-Hwan;Lee, Ji-Woong;Kim, Tae-Hun;Choi, Bong-Hwan
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.1
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    • pp.23-28
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    • 2016
  • The Fas (APO-1, TNFRSF6) gene known as a member of the tumor necrosis factor receptor superfamily was selected for DNA marker development in Korean cattle. It is a cell membrane protein and mediates programmed cell death (apoptosis). We discovered single nucleotide polymorphisms (SNPs) within Fas gene in order to develop novel DNA markers related to economical traits at the genomic level. The sequences of whole exon and 1 kb range of both front and back of the gene were determined by direct-sequencing methods using 24 cattle. A total of 55 SNPs were discovered and we selected 31 common polymorphic sites considering their allele frequencies, haplotype-tagging status and linkage disequilibrium (LD) for genotyping in larger-scale subjects. The SNPs were confirmed genotype through the SNaPshot method (n = 274) and were examined for a possible genetic association between Fas polymorphisms and marbling score. So, the SNPs that were identified significant are g.30256G>C, g.31474C>A, g.31940A>G, and g.32982G>A. These results suggest that SNPs of Fas gene were associated with intramuscular fat content of meat quality traits in Korean cattle.

LH-FAS v2: Head Pose Estimation-Based Lightweight Face Anti-Spoofing (LH-FAS v2: 머리 자세 추정 기반 경량 얼굴 위조 방지 기술)

  • Hyeon-Beom Heo;Hye-Ri Yang;Sung-Uk Jung;Kyung-Jae Lee
    • The Journal of the Korea institute of electronic communication sciences
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    • v.19 no.1
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    • pp.309-316
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    • 2024
  • Facial recognition technology is widely used in various fields but faces challenges due to its vulnerability to fraudulent activities such as photo spoofing. Extensive research has been conducted to overcome this challenge. Most of them, however, require the use of specialized equipment like multi-modal cameras or operation in high-performance environments. In this paper, we introduce LH-FAS v2 (: Lightweight Head-pose-based Face Anti-Spoofing v2), a system designed to operate on a commercial webcam without any specialized equipment, to address the issue of facial recognition spoofing. LH-FAS v2 utilizes FSA-Net for head pose estimation and ArcFace for facial recognition, effectively assessing changes in head pose and verifying facial identity. We developed the VD4PS dataset, incorporating photo spoofing scenarios to evaluate the model's performance. The experimental results show the model's balanced accuracy and speed, indicating that head pose estimation-based facial anti-spoofing technology can be effectively used to counteract photo spoofing.

Trans Fatty Acids Intake of a Girls한 High School Students in Pusan by Food Frequency Questionnaire (식품섭취빈도조사법에 의한 부산지역 여자고등학생의 trans 지방산 섭취 수준)

  • 노경희;송영선;문정원
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.5
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    • pp.957-964
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    • 2000
  • To assess trans fatty acids (tFAs) intake of a girls' high school students in Pusan, dietary history and quantitative food frequency questionnaire (FFQ) were surveyed and analyzed with a total subjects of 274, 268 in summer and winter respectively. It was shown that 38.0% of subjects which was the highest percentage, had snack twice a day in frequency of snack intake. The most favorite snack of subjects was ice cream (46.4%), the preference for milk and dairy products was considerably high. 43.4% of subjects responded to once a month in frequency of dining out. They preferred grilled pork (39.1%), hamburger (36.9%), grilled beef (26.6%) in order. It was also appeared that they preferred fast food. In the case of eating bread, 8.0% of subjects ate bread and margarine, 7.1% butter. Generally, the subjects preferred margarine to butter. tFAs intake for each person per day was $4.24{\pm}0.18\;g$. There was significant difference in tFAs intake according to parents income (p<0.05), frequency of snack intake (p<0.001) and that of dining out (p<0.05). tFAs intake produced naturally (N-tFAs) was $0.86{\pm}0.00\;g$ which corresponded to 20.3% of total tFAs intake per day. tFAs intake produced artificially (H-tFAs) in the process of hardening oil was $3.38{\pm}0.14\;g$, equaled to 79.7% of total tFAs intake per day. There was significant difference between H-tFAs intake for each person per day (p=0.000)

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Expression of Apoptosis-Related Proteins on Germ Cells in Neonatal Mouse Ovary (생쥐 신생자 난소내 생식 세표에서 세포 사멸 관련 단백질의 발현)

  • Cho Dong-Jae;Park Cheol-Hong;Yang Hyunwon;Park Joo-Hyun;Yun Jeong-Mi;Kim Sei-Kwang;Yoon Yong-Dal
    • Development and Reproduction
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    • v.8 no.1
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    • pp.27-33
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    • 2004
  • To investigate the mechanism of germ cell death in postnatal stage of mouse, the involvement of apoptotic executioners, caspase-3 and caspase-activated DNase(CAD), and apoptotic initiators, Bax Fas and Fas ligand, in the germ cell death has been studied. Immune-labels of active caspase-3 and CAD were located in TUNEL-positive, apoptotic, oocytes as well as normal oocytes of primary or secondary follicles. CAD immune-labels were also detected in the nucleus of TUNEL-positive oocytes. Most of oocytes showing positive immune-labeling of active caspase-3 or CAD had vacuoles in their cytoplasm, which is the morphological characteristic of oocyte during folliclar atresia. Bax immune-stains were detected in the atretic oocytes which showed the vacuole in their cytoplasm. Positive immune-labels for Fas ligand was localized in TUNEL-positive or atretic oocytes. Presence of immunoreactivity of active caspase-3 and CAD in TUNEL-positive germ cells implicate that active raspase-3 and CAD might play a role in germ cell apoptosis during early development of mouse ovarian follicle. Immunohistochemical localization of Bax and Fas ligand in TUNEL-positive oocytes suggests that these might be the most plausible modulator of oocyte apoptosis.

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