• Biomedical Science Letters
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• v.29 no.4
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• pp.280-286
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• 2023

In humic substances, fulvic acid (FA) is a subclass of diverse compounds known as humic substances, which are by-products of organic degradation from microorganisms. FA can suppress the proliferation of tumor cells. Despite numerous studies, the exact mechanism for the various effects of FA is not clearly understood. Based on results demonstrating anti-proliferation effects on human cancer, we investigated whether FA has similar effects on lung cancer in this study. Firstly, the anti-cancer effect of FA in pulmonary epithelial tumor cell lines (TC-1 cells) was examined by confirming its inhibitory effect on the cell proliferation of TC-1 cells. TC-1 cell proliferation was reduced by FA on a dose-dependent and time-dependent manner. After 24 hours of FA treatment, cell morphological changes such as cell volume decrease, non-adherence and increased number of apoptotic cells were clearly observed. In addition, FA induced a DNA ladder pattern by increased of DNA fragments in TC-1 cells. In the intracellular regulatory pathway by FA, we confirmed that FA induced the reduction of the anti-apoptotic protein, Bcl-2 protein levels. These results indicate that FA has anticancer effect by inducing intracellular apoptotic pathway. Further research on the mechanism of anticancer effects will be basic data for the development of potential anticancer drugs.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.553-556
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• 2008

This study analyzed is to investigate the effect of the combined use of fly ash and coarse particle cement(RCC) collected in particle classification method during ordinary portland cement(OPC) on the fundamental properties of concrete. Totally 16 batches of the concrete was fabricated vary the contends of FA and RCC. As results of experiment, in the case of flow, the more the contents of RCC, the larger the flow. And the more the contents of FA displacement rate increased, the less the flow. As for simple adiabatic temperature rise due to the RCC and FA contents, it decreased with the increase of them. And particularly in the case of RCC 30% + FA 30%, temperature rise amount, was very low. Compressive strength decreased in proportion to increase of the contents of FA and RCC. And strength ratio of the concrete incorporating FA and RCC for plain concrete at 28 days was 88%${\sim}$98%, which was relatively good results.

• Journal of radiological science and technology
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• v.38 no.2
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• pp.115-120
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• 2015

To study the differences of focal liver lesion image detection at 3 minute, 10 minute and 15 minute time points on gadoxetic acid (GA)'s enhanced MR imaging with a flip angle (FA) of $30^{\circ}$ compared with a $11^{\circ}$. The subjects were 69 patients evaluated with GA enhanced MR imaging with 3.0T MR scanner. The patients are total 35(23 men and 7 women at the mean age of 60.4 years), hepatocellular carcinoma(23) and metastsis(12) except for normal, cyst and hemangioma. After GA was injected, FA $11^{\circ}$ and $30^{\circ}$ images were obtained at 3 minute, 10 minute and 15 minute time points respectively. After quantitative and qualitative assessment of each image was done, statistical analysis was performed by using the independent sample T-test. From both quantitative and qualitative assessment of 3 minute and 10 minute MR images after the injection of GA, FA $30^{\circ}$ images was found to be superior than FA $11^{\circ}$, but there were no statistical significance. However, at 15 minute time point, Statistically significant FA $30^{\circ}$ image(p<0.05) was better than FA $11^{\circ}$ therefore, the FA $30^{\circ}$ improves the focal liver lesion detection. FA $30^{\circ}$ of MR image can detect liver lesion more sensitively than the existing $FA11^{\circ}$ image after GA contrast enhancement at 15 minute time point.

• Proceedings of the Korean Nutrition Society Conference
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• 2000.06a
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• pp.118-118
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• 2000

• The Transactions of the Korea Information Processing Society
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• v.7 no.11
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• pp.3490-3499
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• 2000

There are two approaches, HA(Home Agent)-based and FA(Froegn Agent)-based mulicasting in mobile computing environments based on mobile IP. If we consider efficiency of routing and bandwidth the FA-based model is better than the HA-based model. But in the case of a MH(Mobile Host) moves frequently it shows bad connection durability because of join and graph delays. To overcome this and to support effective mobile multicasting we propose an extended FA-based multicast routing. In our model previous FA for wards multicast packets to MH. while new FA processes a jion request from MH. That is in general case our model supports FA-based multicasting for efficiency but it provides unicast-based mulicasting for connection durability when MH moves to new FN(Roreign Network). To evaluate our model, we analyze connecction durability, bandwidth, overheads and routing sosts in many situations and compare with previous works.

• Journal of Labour Economics
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• v.38 no.4
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• pp.83-107
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• 2015

Free Agent(FA) system allows a professional player to make a salary contract with the other clubs as well as the incumbent one after the player has played in one club for a fixed periods. Sometimes compared with the salary FA players performs very poorly, which leads to a debate about FA busts. We extend the model of Yang and Wang(2013) to the one with incomplete information about the productivity of the player to explain the possibility of FA busts. FA busts do not arise in the separating equilibrium where the private information is fully revealed. The FA busts do occur in the pooling equilibrium We show that the separating equilibrium does not exist. We also show that under some conditions, in particular with strong compensation rule, the unique pooling equilibrium exists.

• Korean Journal of Acupuncture
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• v.38 no.4
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• pp.209-221
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• 2021

Objectives : The aim of this study was to compare and analyze studies related to fire acupuncture (FA) published in South and North Korea. Methods : FA studies published in South Korea were searched through domestic and overseas databases (KISS, RISS, OASIS, and EMBASE). For North Korean studies, databases from the Information Center on North Korea and Korea Institute of Science and Technology Information were used. Among the searched literatures, clinical studies using FA as a treatment intervention were selected (i.e., randomized controlled trials, and case reports). Finally, information such as the disease for which FA was used, the characteristics of FA, and details of treatment methods for FA were extracted from the screened literatures and the results of South and North Korean studies were compared and analyzed. Results : This review included 28 South Korean studies and 9 North Korean studies. All studies in South Korea, except for the three articles that used traditional FA treatment, applied "warm needling"-like acupuncture (WA) in the form of heating the handle of the needle after inserting the needle into the skin, and most studies were conducted on diseases of the musculoskeletal system. Whereas in the North Korean studies, FA was applied to various diseases such as trigeminal neuralgia, skin diseases, and gastrointestinal diseases, and standardized FA tools were used. Conclusions : Studies on traditional FA treatment have rarely been reported in South Korea. The amount of information described in the FA studies in North Korea was limited. In this review, the characteristics of FA treatment tools in South and North Korean studies were mainly analyzed. In the future, FA studies from more diverse perspectives are needed.

• Journal of Korea Multimedia Society
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• v.6 no.1
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• pp.105-113
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• 2003

In CDMA cellular system, inefficient Channel assignment for high-speed mobile host increase call blocking probability For it has been method proposed to guarantee QoS upon tn the speed of hierarchical cell that is allocated Queues and dedicated channels of high speed mobile host's speed. In this paper, We allocated the dedicated channel of high-speed handoff In FA (Foreign Agent), only if the receive signal strength of mobile host in current cell that there is low traffic in HA (Home Agent). also, we created new Circular queue LiFA (Limited Foreign Agent) for high-speed handoff call that signal strength is weak in certain FA, and had this High-speed handoff call to be ready for Life time to the new Circular queue LiFA. Thus improve the rate of the forced call termination.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.11C
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• pp.1-9
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• 2001

The Mobile IP protocol allows IP hosts to move between different networks without changing their IP addresses. The Mobile IP systems supporting the local registration were introduced to reduce the number of times when a home registration with the remotely located Home Agent is needed. The local registration Mobile IP protocol enhanced the performance by processing the MN\`s registration requests at a local agent. However. the local registration approach may consider other aspects of the Mobile IP systems as the FA fault tolerance. In this paper, we will briefly review previous protocols to support the FA fault tolerance in hierarchical local registration Mobile If system and will propose a fault tolerance protocol with backup FA in hierarchical local registration mobile IP t() enhance the efficiency of such systems against Foreign Agent failures.

• Journal for History of Mathematics
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• v.31 no.6
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• pp.273-289
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• 2018

The KaiFangFa開方法 of traditional mathematics was completed in ${\ll}$JiuZhang SuanShu九章算術${\gg}$ originally, and further organized in Song宋 $Yu{\acute{a}}n$元 dinasities. The former is the ShiSuoKaiFangFa釋鎖開方法 using the coefficients of the polynomial expansion, and the latter is the ZengChengKaiFangFa增乘開方法 obtaining the solution only by some mechanical numerical manipulations. ${\ll}$SanHak JeongEui算學正義${\gg}$ basically used the latter and improved the estimate-value array by referring to the written-calculation in ${\ll}$ShuLi JingYun數理精蘊${\gg}$. As a result, ZengChengKaiFangFa was more refined so that the KaiFangFa algorithm is more consistent.