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http://dx.doi.org/10.17946/JRST.2015.38.2.05

Improved Focal Liver Lesion Detection by Increasing Flip Angle During Gadoxetic Acid-Enhancement in MRI  

Lee, SeJy (Department of Medical science Graduate school, Chonnam National University)
Kim, Young-Keun (Dept. of Radiotechnology, Gwang-ju Health university)
Publication Information
Journal of radiological science and technology / v.38, no.2, 2015 , pp. 115-120 More about this Journal
Abstract
To study the differences of focal liver lesion image detection at 3 minute, 10 minute and 15 minute time points on gadoxetic acid (GA)'s enhanced MR imaging with a flip angle (FA) of $30^{\circ}$ compared with a $11^{\circ}$. The subjects were 69 patients evaluated with GA enhanced MR imaging with 3.0T MR scanner. The patients are total 35(23 men and 7 women at the mean age of 60.4 years), hepatocellular carcinoma(23) and metastsis(12) except for normal, cyst and hemangioma. After GA was injected, FA $11^{\circ}$ and $30^{\circ}$ images were obtained at 3 minute, 10 minute and 15 minute time points respectively. After quantitative and qualitative assessment of each image was done, statistical analysis was performed by using the independent sample T-test. From both quantitative and qualitative assessment of 3 minute and 10 minute MR images after the injection of GA, FA $30^{\circ}$ images was found to be superior than FA $11^{\circ}$, but there were no statistical significance. However, at 15 minute time point, Statistically significant FA $30^{\circ}$ image(p<0.05) was better than FA $11^{\circ}$ therefore, the FA $30^{\circ}$ improves the focal liver lesion detection. FA $30^{\circ}$ of MR image can detect liver lesion more sensitively than the existing $FA11^{\circ}$ image after GA contrast enhancement at 15 minute time point.
Keywords
Magnetic resonance imaging (MRI); Gadoxetic acid (GA); Flip angle ( FA); Focal liver lesion;
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