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Machine learning-based Predictive Model of Suicidal Thoughts among Korean Adolescents. (머신러닝 기반 한국 청소년의 자살 생각 예측 모델)

  • YeaJu JIN;HyunKi KIM
    • Journal of Korea Artificial Intelligence Association
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    • v.1 no.1
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    • pp.1-6
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    • 2023
  • This study developed models using decision forest, support vector machine, and logistic regression methods to predict and prevent suicidal ideation among Korean adolescents. The study sample consisted of 51,407 individuals after removing missing data from the raw data of the 18th (2022) Youth Health Behavior Survey conducted by the Korea Centers for Disease Control and Prevention. Analysis was performed using the MS Azure program with Two-Class Decision Forest, Two-Class Support Vector Machine, and Two-Class Logistic Regression. The results of the study showed that the decision forest model achieved an accuracy of 84.8% and an F1-score of 36.7%. The support vector machine model achieved an accuracy of 86.3% and an F1-score of 24.5%. The logistic regression model achieved an accuracy of 87.2% and an F1-score of 40.1%. Applying the logistic regression model with SMOTE to address data imbalance resulted in an accuracy of 81.7% and an F1-score of 57.7%. Although the accuracy slightly decreased, the recall, precision, and F1-score improved, demonstrating excellent performance. These findings have significant implications for the development of prediction models for suicidal ideation among Korean adolescents and can contribute to the prevention and improvement of youth suicide.

Thermal and Dielectric Properties of LiF-Doped MgO Ceramics (LiF첨가 MgO 세라믹스의 열적·유전적 특성)

  • Kim, Shin;Kim, So-Jung;Nam, Kyung-Jin;Cha, Hansol;Yoon, Sang-Ok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.7
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    • pp.419-423
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    • 2015
  • Sintering, microstructure, thermal conductivity and microwave dielectric properties of xLiF-(1-x)MgO ceramics (x=0.03~0.10 mol) were investigated. The high density was obtained in the specimens of $x{\geq}0.06$, i.e., 0.04 LiF-0.96 MgO in mol, whereas the amount of 0.03 mol LiF was insufficient to densify. From the result that the contact flattening in the sintered specimen was observed, the densification occurred through the liquid-phase sintering. The specimen of x=0.06 showed the highest room-temperature thermal conductivity. Relative density, thermal conductivity, dielectric constant, and quality factor ($Q{\times}f$) of the specimen for x=0.06 sintered at $900^{\circ}C$ for 4 h were 97.8%, $39.2Wm^{-1}K^{-1}$, 9.45, and 14,671 GHz, respectively.

Correlation between Depression and Spiritual Health in Women with Cancer (여성암 환자의 영적 건강과 우울의 관계)

  • Tae, Young-Sook;Kim, Mi-Yea
    • Asian Oncology Nursing
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    • v.7 no.2
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    • pp.169-178
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    • 2007
  • Purpose: This study was to identify the relationship between depression and spiritual health in patients suffering from female cancer. Methods: The study utilized a cross-sectional descriptive study design. Data was collected by questionnaires from 106 female patients who were diagnosed with cancer of female organs at three university hospitals and one general hospital. The instruments used in this study included, "the Depression Scale" developed by Zung(1965) and "Spirituality Health Inventory" developed by Highfield(1992) and amended by Kim. The collected data were analyzed using frequency, percentage, t-test, ANOVA, and Pearson's correlation coefficients. Results: There was significantly negative correlation between spiritual health and depression in female cancer patients (r= -.65, p< .0001). There were significant differences in spiritual health according to the monthly income (F=4.30, p= .016), the degree of pain (F=2.85, p= .041), the degree of fatigue (F=3.42, p= .020), the frequency of attendance at worship services (F=3.26, p= .014), the effect of religion on personal life (F=9.41, p= .000). There were significant differences in depression, according to the residence type (F= .75, p= .012), the cancer insurance (t=7.86, p= .006), the degree of pain (F=2.78, p= .045). Conclusions: There is a necessity to develop strategies to improve the spiritual health and to reduce depression in female cancer patients. The significant several characteristics related to depression and spiritual health should be considered in psychsocial nursing intervention of female cancer patients.

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Homology Modeling and Docking Studies of Streptomyces peucetius CYP147F1 as Limonene Hydroxylase

  • Bhattarai, Saurabh;Liou, Kwangkyoung;Oh, Tae-Jin
    • Journal of Microbiology and Biotechnology
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    • v.22 no.7
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    • pp.917-922
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    • 2012
  • Homology modeling of Streptomyces peucetius CYP147F1 was constructed using three cytochrome P450 structures, CYP107L1, CYPVdh, and CYPeryF, as templates. The lowest energy SPCYP147F1 model was then assessed for stereochemical quality and side-chain environment by Accelrys Discovery Studio 3.1 software. Further activesite optimization of the SPCYP147F1 was performed by molecular dynamics to generate the final SPCYP147F1 model. The substrate limonene was then docked into the model. The model-limonene complex was used to validate the active-site architecture, and functionally important residues within the substrate recognition site were identified by subsequent characterization of the secondary structure. The docking of limonene suggested that SPCYP147F1 would have broad specificity with the ligand based on the two different orientations of limonene within the active site facing to the heme. Limonene with C7 facing the heme with distance of $3.4{\AA}$ from the Fe was predominant.

Organometallic fluorine-18 bonds in 18F-radiochemistry

  • Joong-Hyun Chun;Minju Lee;Sungwon Jun;Jeongmin Son
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.1
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    • pp.22-32
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    • 2021
  • Fluorine-18 is by far the most widely exploited radionuclide in PET (positron emission tomography) radiochemistry. The physical half-life of fluorine-18 allows for chemical manipulation within a restricted timeframe, and cyclotron-produced fluoride ion has been widely applied in aliphatic and aromatic nucleophilic radiofluorinations to produce a variety of established radiotracers. Radiotracers have become more structurally complicated to address diverse targets in physiobiological systems. There is therefore an unmet need to complement traditional C-18F bond-forming radiofluorination with new and efficient radiolabeling techniques to tackle the myriad of possible chemical environments. This review discusses recent advances in organometallic fluorine-18 bond creation in 18F-radiochemistry. Although not widely employed, new radiolabeling strategies for constructing boron-18F, silicon-18F, aluminum-18F, and other metal-18F bonds are described in view of their potential use in the development of novel radiopharmaceuticals.

Antifungal Activity and Plant Growth Promotion by Rhizobacteria Inhibiting Growth of Plant Pathogenic Fungi (식물병원성 진균을 억제하는 근권세균의 항진균능과 식물생장촉진능)

  • Jung, Taeck-Kyung;Kim, Ji-Hyun;Song, Hong-Gyu
    • Korean Journal of Microbiology
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    • v.48 no.1
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    • pp.16-21
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    • 2012
  • Since many pesticides cause various health and environmental problems, alternative measures to replace them are needed, and the bacteria producing the antifungal substances can be one of them. In this study, several rhizobacteria were isolated and their antifungal activities against some important plant pathogenic fungi were examined. Pseudomonas otitidis TK1 and Paenibacillus peoriae RhAn32 inhibited the growth of Fusarium oxysporum f. sp. niveum and F. oxysporum f. sp. lycopersici by 49.8% and 45.6%, and 45.1% and 48.3%, respectively compared to those of the control. P. peoriae RhAn32 also decreased the growth of F. oxysporum f. sp. raphani by 37.5%. This growth inhibition might be due to the production of antifungal substances, such as siderophore, hydrogen cyanide and chitinase, which were produced by these rhizobacteria. P. otitidis TK1 also produced plant growth hormones indole acetic acid and indole butyric acid at $293.41{\mu}g/mg$ protein and $418.53{\mu}g/mg$ protein, respectively. When P. otitidis TK1 and B. cereus TK2 were inoculated together with F. oxysporum f. sp. lycopersici to the 4 weeks grown tomato seedlings and incubated additional 8 weeks, the stem lengths of tomato increased up to 45.7% and 55.3% and root lengths were raised to 64.9% and 60.8%, respectively than those of the control group. The wet weights increased by 118% and 182%, respectively compared to the control group.

Flux Melting Route to 2-and 3-dimensional Fibrous Potassium Titanates, K$_2Ti_{2n}O_{4n+1}$ (n = 2 and 3) (Flux 용융법에 의한 2차원 및 3 차원 구조의 티탄산칼륨 섬유의 합성)

  • Jin-Ho Choy;Yang Su Han;Seung Wan Song
    • Journal of the Korean Chemical Society
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    • v.37 no.8
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    • pp.765-772
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    • 1993
  • Two-dimensional potassium tetratitanate ($K_2Ti_4O_9$) and three-dimensional potassium hexatitanate ($K_2Ti_6O_{13}$) fibers have been prepared by the combined method consisting of the flux melting (1150$^{\circ}C$)-slow cooling (cooling rate = 5$^{\circ}C$/h) process from the starting raw materials of $K_2CO_3$, and $TiO_2$ with the flux of $K_2MoO_4$. It was found that the fiber growth reaction is strongly dependent upon the mole ratio of flux (F) to raw material (R), which is 7 : 3 (F : R) as for the optimum growth condition. Relatively long fibers (average length ${\thickapprox}$ 4 mm) with a mixture of $K_2Ti_4O_9$ (major) and $K_2Ti_6O_{13}$ (minor) could be obtained when the reaction was carried out for the $K_2MoO_4-$K_2O{\cdot}4TiO_2$ (F : R = 7 : 3) system, but for the $K_2$MoO_4$-$K_2O{\cdot}6TiO_2$ (F : R = 7: 3) one, only the short fibers with ${\thickapprox}$ 2 mm long could be grown as the mixed phase of $K_2Ti_6O_{13}$ and $K_2Ti_4O_9$.

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Analysis of Technology Association Rules Between CPC Codes of the 'Internet of Things(IoT)' Patent (CPC 코드 기반 사물인터넷(IoT) 특허의 기술 연관성 규칙 분석)

  • Shim, Jaeruen
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.12 no.5
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    • pp.493-498
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    • 2019
  • This study deals with the analysis of the technology association rules between CPC codes of the Internet of Things(IoT) patent, the core of the Fourth Industrial Revolution ICT-based technology. The association rules between CPC codes were extracted using R, an open source for data mining. To this end, we analyzed 369 of the 605 patents related to the Internet of Things filed with the Patent Office until July 2019, with a complex CPC code, up to the subclass-level. As a result of the technology association rules, CPC codes with high support were [H04W ${\rightarrow}$ H04L](18.2%), [H04L ${\rightarrow}$ H04W](18.2%), [G06Q ${\rightarrow}$ H04L](17.3%), [H04L ${\rightarrow}$ G06Q](17.3%), [H04W ${\rightarrow}$ G06Q](9.8%), [G06Q ${\rightarrow}$ H04W](9.8%), [G06F ${\rightarrow}$ H04L](7.9%), [H04L ${\rightarrow}$ G06F](7.9%), [G06F ${\rightarrow}$ G06Q](6.2%), [G06Q ${\rightarrow}$ G06F](6.2%). After analyzing the technology interconnection network, the core CPC codes related to technology association rules are G06Q and H04L. The results of this study can be used to predict future patent trends.

The Preparation of Alkenyl Fluorides form Organometallic Reagents

  • 이승한;Martin Riediker;Jeffrey Schwartz
    • Bulletin of the Korean Chemical Society
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    • v.19 no.7
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    • pp.760-766
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    • 1998
  • Fluorination of alkenyllithium reagents can be accomplished in acceptable yield under conditions which give rise to low competitive alkene formation. These reactions are abetted by the use of the low temperature soluble, mild fluorinating agent N-fluoro-N-tert-butylbenzenesulfonamide; "simpler" fluorinating reagents such as F2, XeF2 or FClO3 failed to give acceptable amounts of the fluoroolefin with these alkenyllithiums.

Influence of Nd2O3 Addition to 0.3CaTiO3-0.7(Li1/2Nb1/2)TiO3 on their Microwave Dielectric Properties (Nd2O3 첨가가 0.3CaTiO3-0.7(Li1/2Nb1/2)TiO3 세라믹스의 마이크로파 유전특성에 미치는 영향)

  • 김범수;박일환;윤상옥;김경용
    • Journal of the Korean Ceramic Society
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    • v.39 no.1
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    • pp.26-32
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    • 2002
  • The effects of $Nd_2O_3$ addition to $Q{\cdot}f_{0}(GHz)$ ceramics with ${\varepsilon}_r$ of 126, $Q{\cdot}f_{0}(GHz)$ of 2240 and of $68\;ppm/^{\circ}C$ on their microwave properties were investigated. For the addition of 5 wt% $Nd_2O_3$, the dielectric constant (${\varepsilon}_r$) showed maximum value of 131, then decreased with the further addition of $Nd_2O_3$. $Q{\cdot}f_{0}(GHz)$ value was still increased to 3533 with 9 wt% $Nd_2O_3$ addition, it is influenced by densification of grain boundary. With more addition of $Nd_2O_3$ up to 18 wt%, the abnormal grain growth have influence on the decreasing of $Q{\cdot}f_{0}(GHz)$ value. But with the further addition of $Nd_2O_3$ over 25 wt%, the $Q{\cdot}f_{0}(GHz)$ value was again increased by the effect of the second phase ($Nd_2Ti_2O_7$) forming. The temperature coefficient of resonant frequency (${\tau}_f$) was decreased from $+\;68\;ppm/^{\circ}C$ with the addition of $Nd_2O_3$, reached $0\;ppm/^{\circ}C$ at 12 wt% addition, and became negative with the further addition of $Nd_2O_3$. The optimum microwave dielectric properties were obtained for $0.3CaTiO_3-0.7(Li_{1/2}Nd_{1/2})TiO_3$ with 9 wt% $Nd_2O_3$ sintered at $1425^{\circ}C$ for 3 hrs. The dielectric constant (${\varepsilon}_r$), the $Q{\cdot}f_{0}(GHz)$ value, and the temperature coefficient of resonant frequency (${\tau}_f$) were 108, 3533, and $+\;6\;ppm/^{\circ}C$, respectively.